GO:0042605

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Name peptide antigen binding
Categary Function
Go Slim No
Go Link GO:0042605
Unique Molecular Interactions 102
Total Molecular Interactions 124
Total Single Events 906
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for peptide antigen binding. They are ordered first by their pain relevance and then by number of times they were reported for peptide antigen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69057 H2-M3 Regulation of Klkb1 1 0.00 0.42 2.71
2 INT32586 H2-Ab1 Regulation of Pomc 1 0.03 0.14 2.19
3 INT32585 H2-Ab1 Negative_regulation of Pomc 1 0.03 0.13 2
4 INT29093 Binding of H2-Ab1 and Rbm39 1 0.06 0 1.5
5 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
6 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
7 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
8 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
9 INT145408 H2-Ab1 Negative_regulation of Gene_expression of Dbi 1 0.05 0 1.06
10 INT161520 H2-M3 Regulation of Positive_regulation of Mapk1 1 0.09 0.47 0.79
11 INT86657 TNF Regulation of H2-Ab1 1 0.02 0.84 0.74
12 INT14178 DHCR24 Positive_regulation of Localization of PDYN 1 0.05 0 0.72
13 INT14177 DHCR24 Positive_regulation of PDYN 1 0.05 0 0.71
14 INT112218 Ntsr2 Positive_regulation of H2-Ab1 1 0.06 0 0.64
15 INT49358 Binding of DHCR24 and Pdyn 1 0.00 0 0.53
16 INT119598 H2-Ab1 Regulation of Scn4a 1 0.00 0.09 0.46
17 INT161521 Negative_regulation of H2-M3 Positive_regulation of Mapk1 1 0.14 0.41 0.42
18 INT161522 H2-M3 Positive_regulation of Mapk1 1 0.15 0.41 0.41
19 INT353669 Binding of SNRNP70 and CD209 1 0.04 6.08 0.35
20 INT119603 H2-Ab1 Regulation of EDNRA 1 0.00 0.07 0.32
21 INT119602 EDNRA Regulation of H2-Ab1 1 0.00 0.07 0.32
22 INT143809 Negative_regulation of Abcc2 Positive_regulation of Positive_regulation of H2-M3 1 0.04 0 0.25
23 INT135463 Binding of DHCR24 and Fos 1 0.35 0.17 0.19
24 INT135462 Binding of DHCR24 and Cfp 1 0.00 0.17 0.18
25 INT132267 Binding of SGCG and Tap1 1 0.05 0.24 0.18
26 INT316769 Binding of H2-K1 and Hspa9 1 0.08 1.02 0.15
27 INT188700 Il6 Positive_regulation of H2-Eb1 1 0.01 0.18 0.14
28 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14
29 INT180715 Binding of SARS and CLEC4M 2 0.12 2.92 0.11
30 INT317243 Npy Positive_regulation of Tap2 1 0.08 0 0.1
31 INT317260 Pyy Positive_regulation of Tap2 1 0.09 0 0.1
32 INT149185 Regulation of H2-Ab1 Regulation of Trpv1 1 0.34 0.52 0.08
33 INT149184 H2-Ab1 Regulation of Trpv1 1 0.34 0.52 0.08
34 INT154716 Binding of MON1B and CD209 1 0.01 1.76 0.08
35 INT353666 Gene_expression of CD209 Negative_regulation of GOPC 1 0.06 0.67 0.08
36 INT262638 Binding of HLA-DQB1 and AICDA 1 0.03 1.34 0.06
37 INT317257 Binding of Tap2 and Pyy 1 0.06 0 0.05
38 INT317242 Binding of Tap2 and Npy 1 0.05 0 0.05
39 INT262643 Binding of HLA-DQB1 and HLA-DRB1 1 0.10 0.45 0.05
40 INT181168 Binding of CD79A and TAPBP 1 0.10 0.7 0.04
41 INT296712 Binding of H2-K1 and GOPC 1 0.00 0.41 0.04
42 INT225027 Binding of TAPBP and TRERF1 1 0.33 0 0.04
43 INT92381 Binding of HLA-B and Tap1 1 0.01 0 0
44 INT245701 CNOT1 Positive_regulation of H2-Q9 1 0.01 0.31 0
45 INT342363 Binding of H2-K1 and OSBPL1A 1 0.11 0 0
46 INT181169 TAPBP Negative_regulation of MALT1 1 0.00 0.48 0
47 INT189115 Binding of Esr1 and Tap1 1 0.07 0.05 0
48 INT181167 TAPBP Negative_regulation of CD79A 1 0.11 0.48 0
49 INT189117 TAP1 Positive_regulation of Tap1 1 0.44 0.45 0
50 INT228108 Il10 Negative_regulation of H2-Eb1 1 0.04 1.38 0
51 INT110162 Binding of HLA-B and HLA-DQB1 1 0.09 0 0
52 INT171757 Binding of MMP2 and SLC7A5 1 0.03 0.29 0
53 INT258910 Binding of HLA-DQA1 and HLA-DQB1 1 0.17 0.22 0
54 INT189112 Tap1 Positive_regulation of Gene_expression of Mthfd1 1 0.07 0.3 0
55 INT250952 Binding of TAP1 and USO1 1 0.02 0 0
56 INT181165 TAPBP Regulation of Gene_expression of CD79A 1 0.07 0.35 0
57 INT342360 Binding of H2-K1 and Irs1 1 0.10 0 0
58 INT189109 Tap1 Regulation of Tap2 1 0.27 0.29 0
59 INT353661 Binding of CD209 and SENP8 1 0.07 1.39 0
60 INT236079 Binding of AGER and HLA-DQB1 1 0.25 1.06 0
61 INT159710 Binding of Tap1 and ERAP1 1 0.04 0.11 0
62 INT353664 SNRNP70 Regulation of Gene_expression of CD209 1 0.05 1.62 0
63 INT189104 Negative_regulation of Binding of Esr1 and Tap1 1 0.08 0.06 0
64 INT236077 Binding of HLA-DQB1 and TNF 1 0.29 1.06 0
65 INT189107 Binding of Atp8a1 and Tap1 1 0.39 0 0
66 INT353668 Binding of ICAM3 and CD209 1 0.15 3.05 0
67 INT189113 Gene_expression of Tap1 Positive_regulation of Gene_expression of H2-D1 1 0.05 0.47 0
68 INT236076 Binding of HLA-DQB1 and LTA 1 0.25 1.06 0
69 INT185354 Binding of Egfr and H2-Ab1 1 0.42 0.69 0
70 INT189103 Binding of Tap1 and Tap2 1 0.21 0.08 0
71 INT323252 Binding of H2-Ab1 and Isl1 1 0.00 0.6 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for peptide antigen binding. They are ordered first by their pain relevance and then by number of times they were reported in peptide antigen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101140 Negative_regulation of Tap1 7 0.50 9.08 17.46
2 INT22516 Gene_expression of H2-M3 17 0.25 2.98 13.59
3 INT11766 Negative_regulation of H2-Ab1 15 0.43 5.27 12.32
4 INT3699 Gene_expression of H2-Ab1 24 0.74 12.06 11.82
5 INT2956 Binding of H2-Ab1 19 0.37 3.1 11.18
6 INT23229 Positive_regulation of H2-M3 11 0.04 1.87 8.56
7 INT28181 Regulation of H2-M3 7 0.07 0.82 8.38
8 INT10568 Regulation of H2-Ab1 9 0.20 1.86 6.79
9 INT14054 Positive_regulation of H2-Ab1 10 0.69 2.98 6.25
10 INT54257 Binding of H2-M3 5 0.03 0.71 4.68
11 INT69396 Gene_expression of H2-K1 72 0.65 38.16 4.56
12 INT55611 Negative_regulation of H2-M3 6 0.46 0.59 3.84
13 INT123908 Positive_regulation of HLA-DQB1 12 0.21 10.5 3.71
14 INT271447 Positive_regulation of Positive_regulation of HLA-DQB1 1 0.06 5.87 2.8
15 INT96273 Binding of TAP1 4 0.37 4.27 2.67
16 INT11476 Positive_regulation of H2-K1 17 0.26 9.48 2.23
17 INT93753 Positive_regulation of Tap2 1 0.57 1.31 2.21
18 INT8911 Regulation of DHCR24 1 0.05 1.91 1.71
19 INT58069 Transcription of H2-Ab1 2 0.50 1.06 1.59
20 INT152612 Positive_regulation of Binding of H2-M3 1 0.04 0.07 1.57
21 INT99861 Positive_regulation of Regulation of H2-Ab1 1 0.21 0.8 1.49
22 INT204181 Gene_expression of CD209 22 0.64 30.66 1.47
23 INT271448 Regulation of HLA-DQB1 1 0.06 2.73 1.4
24 INT189092 Gene_expression of Tap1 56 0.76 14.09 1.33
25 INT89426 Binding of HLA-DRB3 2 0.41 1.77 1.32
26 INT50761 Negative_regulation of H2-Q9 1 0.01 0.79 1.22
27 INT59029 Positive_regulation of DHCR24 2 0.22 0.51 1.18
28 INT108077 Regulation of Regulation of H2-Ab1 1 0.04 0 1.1
29 INT132531 Positive_regulation of TAPBP 8 0.49 2.84 1.09
30 INT56098 Gene_expression of HLA-DRB3 5 0.59 2.89 0.99
31 INT110163 Binding of HLA-DQB1 8 0.25 4.71 0.98
32 INT11765 Positive_regulation of Gene_expression of H2-Ab1 3 0.41 0.36 0.97
33 INT79115 Binding of Tap1 12 0.47 4.21 0.95
34 INT192496 Positive_regulation of Gene_expression of H2-K1 13 0.26 8.44 0.92
35 INT69397 Regulation of Gene_expression of H2-K1 9 0.23 6.32 0.91
36 INT122101 Negative_regulation of Tap2 4 0.25 0.36 0.82
37 INT4762 Negative_regulation of DHCR24 5 0.45 0.68 0.8
38 INT25173 Localization of H2-M3 3 0.17 0.59 0.8
39 INT140449 Positive_regulation of Tap1 5 0.68 1.84 0.74
40 INT132528 Gene_expression of TAPBP 17 0.65 5.93 0.69
41 INT44118 Binding of CD209 10 0.35 8.83 0.69
42 INT96840 Negative_regulation of H2-K1 7 0.33 1.35 0.67
43 INT27912 Regulation of H2-K1 9 0.35 2.83 0.65
44 INT77152 Positive_regulation of Positive_regulation of H2-K1 2 0.26 1.12 0.64
45 INT315355 Negative_regulation of Gene_expression of H2-K1 1 0.22 1.66 0.64
46 INT14053 Regulation of Positive_regulation of H2-Ab1 1 0.09 0.32 0.63
47 INT78257 Transcription of Tap2 1 0.28 0.59 0.62
48 INT50760 Negative_regulation of Negative_regulation of H2-Q9 1 0.01 0.4 0.61
49 INT14052 Positive_regulation of Positive_regulation of H2-Ab1 1 0.10 0.31 0.61
50 INT11458 Binding of Tap2 3 0.39 2.51 0.57
51 INT9688 Localization of Tap1 3 0.73 0.96 0.57
52 INT78254 Gene_expression of Tap2 4 0.54 2.59 0.56
53 INT11477 Negative_regulation of Positive_regulation of H2-K1 2 0.01 0.98 0.54
54 INT285551 Negative_regulation of HLA-DQB1 1 0.03 1.08 0.54
55 INT38704 Negative_regulation of HLA-DRB3 2 0.37 0.9 0.5
56 INT152682 Negative_regulation of Gene_expression of H2-Ab1 4 0.34 3.3 0.46
57 INT139674 Regulation of TAPBP 2 0.44 1.34 0.46
58 INT89425 Positive_regulation of HLA-DRB3 2 0.59 2.38 0.42
59 INT136443 Negative_regulation of Binding of H2-Ab1 1 0.30 0.65 0.39
60 INT144659 Phosphorylation of H2-Ab1 1 0.01 0 0.39
61 INT14181 Binding of DHCR24 1 0.04 0 0.34
62 INT78256 Regulation of Gene_expression of Tap2 2 0.28 0.38 0.32
63 INT315353 Localization of H2-K1 2 0.30 1.28 0.31
64 INT143502 Regulation of Tap1 2 0.40 0.75 0.29
65 INT222804 Positive_regulation of Gene_expression of CD209 6 0.48 6.44 0.28
66 INT247952 Binding of H2-K1 4 0.09 3.32 0.28
67 INT137615 Regulation of Gene_expression of H2-Ab1 2 0.59 1.32 0.28
68 INT143804 Negative_regulation of Localization of H2-M3 1 0.03 0 0.26
69 INT143808 Positive_regulation of Localization of H2-M3 1 0.03 0 0.26
70 INT316768 Regulation of Localization of H2-K1 1 0.11 0.95 0.25
71 INT117251 Positive_regulation of Localization of TAPBP 1 0.40 0.8 0.22
72 INT111912 Negative_regulation of TAP1 1 0.04 0.41 0.22
73 INT117250 Localization of TAPBP 1 0.61 0.8 0.22
74 INT245196 Negative_regulation of CD209 5 0.11 4.83 0.21
75 INT135460 Gene_expression of DHCR24 2 0.58 0.57 0.2
76 INT135459 Positive_regulation of Negative_regulation of DHCR24 1 0.38 0.18 0.19
77 INT132529 Binding of TAPBP 8 0.47 1.43 0.18
78 INT135461 Protein_catabolism of DHCR24 1 0.44 0.27 0.17
79 INT222810 Positive_regulation of CD209 4 0.48 3.14 0.16
80 INT258918 Negative_regulation of Gene_expression of HLA-DRB3 1 0.22 1.52 0.13
81 INT243261 Gene_expression of TAP1 1 0.05 0.1 0.1
82 INT243262 Localization of TAP1 1 0.06 0.09 0.09
83 INT257933 Negative_regulation of Positive_regulation of H2-Ab1 1 0.05 0.14 0.08
84 INT219617 Negative_regulation of Positive_regulation of Tap1 1 0.27 1.03 0.07
85 INT172369 Negative_regulation of Gene_expression of TAPBP 1 0.09 0.25 0.07
86 INT171766 Transcription of SLC7A5 1 0.06 0.43 0.05
87 INT181175 Negative_regulation of TAPBP 1 0.35 0.81 0.05
88 INT353675 Transcription of CD209 1 0.50 1.5 0.04
89 INT192495 Phosphorylation of H2-K1 1 0.01 1.38 0.04
90 INT354841 Regulation of HLA-DRB3 1 0.01 1.88 0.04
91 INT130485 Gene_expression of SLC7A5 2 0.65 0 0.03
92 INT326371 Localization of SLC7A5 1 0.73 0 0.03
93 INT353676 Regulation of Gene_expression of CD209 1 0.22 0.43 0.03
94 INT189097 Positive_regulation of Gene_expression of Tap1 18 0.68 2.67 0
95 INT204182 Localization of CD209 2 0.13 0.89 0
96 INT258915 Gene_expression of HLA-DQB1 2 0.44 0.72 0
97 INT189089 Regulation of Binding of Tap1 1 0.38 0 0
98 INT247117 Localization of HLA-DQB1 1 0.01 1.53 0
99 INT335230 Positive_regulation of TAP1 1 0.01 0.07 0
100 INT222793 Binding of CLEC4M 1 0.05 0.56 0
101 INT193182 Localization of DHCR24 1 0.10 0.22 0
102 INT293971 Regulation of Regulation of H2-K1 1 0.06 0.05 0
103 INT132530 Positive_regulation of Binding of TAPBP 1 0.67 0.08 0
104 INT353677 Regulation of CD209 1 0.26 0.82 0
105 INT222809 Positive_regulation of Gene_expression of CLEC4M 1 0.05 0.67 0
106 INT293970 Positive_regulation of Regulation of H2-K1 1 0.11 0.05 0
107 INT189094 Positive_regulation of Gene_expression of Tap2 1 0.37 0.14 0
108 INT187455 Gene_expression of H2-Eb1 1 0.27 0.21 0
109 INT353680 Positive_regulation of Transcription of CD209 1 0.44 1.09 0
110 INT189099 Localization of Tap2 1 0.39 0.33 0
111 INT189091 Regulation of Gene_expression of Tap1 1 0.44 0.18 0
112 INT189098 Transcription of Tap1 1 0.67 0.32 0
113 INT243348 Regulation of TAP1 1 0.05 0.08 0
114 INT245695 Gene_expression of H2-Q9 1 0.01 0.27 0
115 INT189095 Negative_regulation of Gene_expression of Tap1 1 0.36 0.22 0
116 INT189090 Negative_regulation of Localization of Tap1 1 0.42 0.38 0
117 INT132527 Positive_regulation of Gene_expression of TAPBP 1 0.49 0.84 0
118 INT222807 Gene_expression of CLEC4M 1 0.06 0.67 0
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