GO:0043237

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Latest revision as of 07:04, 22 January 2013

Name laminin-1 binding
Categary Function
Go Slim No
Go Link GO:0043237
Unique Molecular Interactions 60
Total Molecular Interactions 83
Total Single Events 444
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

[edit] Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for laminin-1 binding. They are ordered first by their pain relevance and then by number of times they were reported for laminin-1 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82
2 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7
3 INT179844 Nid1 Regulation of Negative_regulation of Il11 1 0.19 0 0.29
4 INT189670 CHKB Negative_regulation of Gene_expression of DAG1 1 0.11 0 0.24
5 INT335464 Binding of DAG1 and PRKCA 1 0.03 0 0.22
6 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
7 INT189563 Binding of SLIT2 and ROBO4 1 0.03 0.71 0.18
8 INT352763 Sms Regulation of Gene_expression of DAG1 1 0.08 0.64 0.11
9 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
10 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
11 INT352766 DAG1 Positive_regulation of Prkd1 1 0.15 0.38 0.07
12 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
13 INT140771 Binding of NTN4 and Unc5a 1 0.02 0.35 0.07
14 INT140770 Binding of NTN4 and Unc5a 1 0.01 0.35 0.07
15 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
16 INT352762 DAG1 Regulation of Sms 1 0.03 0.37 0.05
17 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
18 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
19 INT352764 DAG1 Positive_regulation of Sms 1 0.06 0.11 0.03
20 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
21 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
22 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
23 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
24 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
25 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
26 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
27 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
28 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
29 INT180854 Binding of FBLN2 and NID1 1 0.01 0.92 0
30 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
31 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
32 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
33 INT230762 Binding of DAG1 and Tbx15 1 0.00 0.21 0
34 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
35 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
36 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
37 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
38 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
39 INT180859 Binding of COL1A1 and NID1 1 0.01 0.9 0
40 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
41 INT180863 Binding of COL5A2 and NID1 1 0.00 0.91 0
42 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
43 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
44 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
45 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
46 INT352765 DAG1 Regulation of Localization of Prkd1 1 0.09 0.09 0
47 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
48 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
49 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0

[edit] Single Events

The table below shows the top 100 pain related interactions that have been reported for laminin-1 binding. They are ordered first by their pain relevance and then by number of times they were reported in laminin-1 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
2 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
3 INT173328 Positive_regulation of DAG1 6 0.31 1.74 1.36
4 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
5 INT189771 Gene_expression of DAG1 5 0.27 4.14 1.12
6 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
7 INT64044 Localization of DAG1 3 0.59 0.27 0.87
8 INT206484 Localization of Shh 2 0.75 1.14 0.46
9 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
10 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
11 INT284325 Positive_regulation of Gene_expression of DAG1 3 0.13 1.08 0.36
12 INT179813 Regulation of Nid1 1 0.33 0 0.29
13 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
14 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
15 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
16 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
17 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
18 INT196355 Protein_catabolism of NID1 1 0.11 0.39 0.16
19 INT196358 Positive_regulation of Localization of NID1 1 0.06 0.44 0.16
20 INT196356 Localization of NID1 1 0.09 0.44 0.16
21 INT196354 Negative_regulation of Localization of NID1 1 0.05 0.44 0.16
22 INT253190 Localization of Shh 2 0.77 1.06 0.13
23 INT140759 Binding of NTN4 1 0.19 1.57 0.13
24 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
25 INT189625 Binding of SLIT2 3 0.33 0.49 0.12
26 INT270442 Transcription of Shh 1 0.53 0.25 0.09
27 INT213515 Binding of Shh 8 0.37 1.92 0.08
28 INT270453 Regulation of Shh 1 0.27 0.83 0.08
29 INT205973 Binding of SHH 3 0.35 1.03 0.07
30 INT140758 Gene_expression of NTN4 1 0.31 0.29 0.07
31 INT179792 Gene_expression of Nid1 1 0.56 0.21 0.07
32 INT256862 Regulation of Shh 1 0.25 0 0.07
33 INT341884 Positive_regulation of Localization of DAG1 1 0.03 0.21 0.06
34 INT352747 Regulation of DAG1 1 0.16 0.99 0.05
35 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
36 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
37 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
38 INT179815 Positive_regulation of Gene_expression of Nid1 1 0.50 0 0.04
39 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
40 INT253181 Transcription of Shh 1 0.68 0.54 0.03
41 INT179829 Negative_regulation of Nid1 1 0.42 0 0.03
42 INT140751 Regulation of NTN4 1 0.11 0.32 0
43 INT352742 Regulation of Gene_expression of DAG1 1 0.12 0.14 0
44 INT213595 Localization of SLIT2 1 0.67 0.06 0
45 INT213593 Gene_expression of SLIT2 1 0.60 0 0
46 INT230759 Binding of DAG1 1 0.03 0.21 0
47 INT179801 Positive_regulation of Nid1 1 0.50 0.06 0
48 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
49 INT140748 Positive_regulation of NTN4 1 0.20 0.31 0
50 INT179825 Localization of Nid1 1 0.44 0 0
51 INT179804 Regulation of Transcription of Nid1 1 0.33 0 0
52 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
53 INT290929 Binding of Shh 1 0.31 0.1 0
54 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
55 INT179808 Transcription of Nid1 1 0.50 0 0
56 INT352733 Negative_regulation of Localization of DAG1 1 0.11 0.06 0
57 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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