GO:0043394

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Name proteoglycan binding
Categary Function
Go Slim No
Go Link GO:0043394
Unique Molecular Interactions 37
Total Molecular Interactions 66
Total Single Events 123
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for proteoglycan binding. They are ordered first by their pain relevance and then by number of times they were reported for proteoglycan binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
2 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
3 INT150791 THBS1 Negative_regulation of TIMP2 1 0.17 0.5 0.52
4 INT150796 ZNF398 Positive_regulation of THBS1 1 0.06 0.5 0.52
5 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
6 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24
7 INT115875 Col5a1 Positive_regulation of Localization of Gcg 1 0.08 0 0.23
8 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21
9 INT189563 Binding of SLIT2 and ROBO4 1 0.03 0.71 0.18
10 INT337260 ELL Positive_regulation of Gene_expression of THBS1 1 0.11 0.82 0.18
11 INT337263 ELL Regulation of Gene_expression of THBS1 1 0.10 0.82 0.18
12 INT231677 Binding of CD47 and THBS1 1 0.18 0 0.16
13 INT252352 Binding of THBS1 and Sirpa 1 0.00 0.26 0.15
14 INT294439 KLK4 Negative_regulation of THBS1 1 0.01 0 0.1
15 INT87037 Binding of FBXO6 and Col5a3 1 0.00 0.48 0.09
16 INT87038 Binding of ADRA1D and Col5a3 1 0.03 0.48 0.09
17 INT294608 Binding of Serpinh1 and Col5a1 1 0.03 0.45 0.09
18 INT341535 F2RL1 Positive_regulation of Gene_expression of THBS1 1 0.28 0.75 0.04
19 INT272528 THBS1 Positive_regulation of TGFB2 1 0.09 0.64 0.03
20 INT337270 E2F1 Positive_regulation of Transcription of THBS1 1 0.67 0.19 0
21 INT337268 E2F1 Regulation of Transcription of THBS1 1 0.44 0 0
22 INT337274 E2F1 Regulation of THBS1 1 0.44 0 0
23 INT337269 Binding of E2F1 and Positive_regulation of Gene_expression of THBS1 1 0.45 0.21 0
24 INT337262 PRB1 Negative_regulation of THBS1 1 0.18 0.61 0
25 INT262750 GLYR1 Positive_regulation of THBS1 1 0.01 0.99 0
26 INT99769 Thbs1 Regulation of THBS1 1 0.00 0 0
27 INT337264 Binding of E2F1 and THBS1 1 0.47 0.78 0
28 INT268524 MYC Regulation of THBS1 1 0.02 1.85 0
29 INT337273 E2F1 Regulation of Gene_expression of THBS1 1 0.60 0 0
30 INT337266 E2F1 Positive_regulation of Gene_expression of THBS1 1 0.67 0.21 0
31 INT99772 Pgr Regulation of THBS1 1 0.00 0 0
32 INT253020 Pttg1 Negative_regulation of THBS1 1 0.03 0.16 0
33 INT337265 Negative_regulation of E2F1 Positive_regulation of THBS1 1 0.42 0 0
34 INT337272 E2F1 Positive_regulation of THBS1 1 0.49 1.27 0
35 INT337267 THBS1 Positive_regulation of E2F1 1 0.49 0.05 0
36 INT99771 Oxtr Regulation of THBS1 1 0.01 0 0
37 INT268511 MIR19B1 Regulation of THBS1 1 0.20 0.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for proteoglycan binding. They are ordered first by their pain relevance and then by number of times they were reported in proteoglycan binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45
2 INT124862 Gene_expression of Col5a1 4 0.17 2.05 2.32
3 INT60337 Positive_regulation of THBS1 8 0.46 4.69 1.83
4 INT124861 Positive_regulation of Col5a1 2 0.09 0.75 1.27
5 INT288546 Regulation of Positive_regulation of THBS1 1 0.36 2.65 1.27
6 INT150805 Localization of THBS1 4 0.46 2.88 1.23
7 INT63014 Gene_expression of Col5a3 1 0.00 2.13 1.13
8 INT99767 Regulation of THBS1 18 0.42 11.51 1.03
9 INT124858 Negative_regulation of Positive_regulation of Col5a1 1 0.01 0.75 0.64
10 INT252993 Negative_regulation of THBS1 8 0.55 6.93 0.59
11 INT150808 Negative_regulation of Localization of THBS1 1 0.25 0.5 0.53
12 INT63013 Positive_regulation of Gene_expression of Col5a3 1 0.00 1.01 0.53
13 INT268576 Positive_regulation of Gene_expression of THBS1 2 0.64 2.26 0.47
14 INT236948 Positive_regulation of Gene_expression of Col5a1 1 0.10 1.15 0.41
15 INT131134 Regulation of Col5a1 1 0.06 0 0.32
16 INT115873 Negative_regulation of Col5a1 1 0.06 0 0.22
17 INT178504 Positive_regulation of Localization of THBS1 2 0.05 1.9 0.19
18 INT231474 Binding of THBS1 4 0.34 2.04 0.16
19 INT189625 Binding of SLIT2 3 0.33 0.49 0.12
20 INT294469 Transcription of THBS1 2 0.66 0.46 0.03
21 INT231690 Negative_regulation of Binding of THBS1 1 0.16 0.37 0.03
22 INT337281 Regulation of Gene_expression of THBS1 1 0.57 0.48 0
23 INT252974 Positive_regulation of Negative_regulation of THBS1 1 0.03 0.09 0
24 INT213595 Localization of SLIT2 1 0.67 0.06 0
25 INT213593 Gene_expression of SLIT2 1 0.60 0 0
26 INT252970 Negative_regulation of Positive_regulation of THBS1 1 0.04 0.2 0
27 INT207312 Phosphorylation of THBS1 1 0.43 0.28 0
28 INT337279 Positive_regulation of Binding of THBS1 1 0.46 0 0
29 INT320827 Negative_regulation of Gene_expression of THBS1 1 0.03 1.52 0
30 INT337283 Positive_regulation of Regulation of THBS1 1 0.46 0 0
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