GO:0043569

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Name negative regulation of insulin-like growth factor receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0043569
Unique Molecular Interactions 17
Total Molecular Interactions 20
Total Single Events 186
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of insulin-like growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of insulin-like growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
2 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
3 INT160048 INPPL1 Regulation of Gene_expression of AKT1 1 0.28 0.6 0.42
4 INT339336 Binding of NKX3-1 and TAC4 1 0.03 0.08 0.18
5 INT275461 Binding of Atxn1 and Atxn2 1 0.39 1.1 0.17
6 INT354120 Binding of IGF2 and IGFBP5 1 0.01 0.45 0.09
7 INT165157 Gli1 Regulation of Igfbp5 1 0.24 0.07 0.09
8 INT208555 YWHAQ Positive_regulation of Atxn1 1 0.77 1.02 0.08
9 INT312219 Binding of IGF1 and IGFBP5 1 0.02 0.13 0.08
10 INT312226 INPP5K Positive_regulation of IGFBP5 1 0.12 0.07 0.05
11 INT235168 Binding of Crx and Atxn7 1 0.11 0.81 0.03
12 INT234978 Binding of Dsg3 and Positive_regulation of Inppl1 1 0.00 0.32 0.03
13 INT235166 Binding of Hdac3 and Atxn1 1 0.02 0.28 0
14 INT269947 Sox17 Positive_regulation of Gene_expression of Atxn1 1 0.08 0 0
15 INT235164 Binding of Atxn1 and Ncor2 1 0.15 0.42 0
16 INT235169 Gene_expression of Dnaja1 Negative_regulation of Binding of Atxn1 1 0.09 0.47 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of insulin-like growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of insulin-like growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181809 Gene_expression of Atxn1 81 0.77 28.66 1.42
2 INT84726 Gene_expression of NKX3-1 4 0.75 2.1 0.75
3 INT181281 Localization of NKX3-1 1 0.12 0.3 0.5
4 INT84724 Negative_regulation of Gene_expression of NKX3-1 1 0.41 0.43 0.44
5 INT160053 Gene_expression of INPPL1 1 0.55 0.6 0.42
6 INT181803 Binding of Atxn1 12 0.48 7 0.3
7 INT268478 Negative_regulation of Positive_regulation of Igfbp5 1 0.26 0.64 0.26
8 INT268477 Positive_regulation of Igfbp5 1 0.31 0.63 0.25
9 INT181806 Positive_regulation of Gene_expression of Atxn1 6 0.41 2.85 0.21
10 INT312242 Binding of IGFBP5 2 0.08 0.69 0.18
11 INT165152 Gene_expression of Igfbp5 1 0.70 0.13 0.18
12 INT339342 Binding of NKX3-1 1 0.04 0.08 0.18
13 INT181807 Positive_regulation of Atxn1 12 0.34 3.96 0.15
14 INT181813 Negative_regulation of Gene_expression of Atxn1 9 0.42 3.47 0.15
15 INT268476 Protein_catabolism of Igfbp5 1 0.40 0.25 0.13
16 INT165155 Regulation of Igfbp5 1 0.55 0.07 0.09
17 INT312250 Protein_catabolism of IGFBP5 1 0.22 0.24 0.08
18 INT181805 Transcription of Atxn1 4 0.69 1.78 0.06
19 INT200842 Negative_regulation of Binding of Atxn1 2 0.35 0.71 0.06
20 INT67340 Localization of IGFBP5 1 0.55 0.17 0.06
21 INT235160 Gene_expression of Atxn7 1 0.56 2 0.04
22 INT312249 Gene_expression of IGFBP5 1 0.18 0.07 0.04
23 INT235137 Positive_regulation of Atxn7 1 0.42 0.71 0.03
24 INT235139 Localization of Atxn7 1 0.67 0.7 0.03
25 INT181802 Localization of Atxn1 6 0.65 3.15 0
26 INT181801 Regulation of Atxn1 3 0.29 1.08 0
27 INT181810 Positive_regulation of Protein_catabolism of Atxn1 1 0.25 0 0
28 INT235141 Binding of Atxn7 1 0.40 0.81 0
29 INT181799 Protein_catabolism of Atxn1 1 0.44 0 0
30 INT235136 Positive_regulation of Localization of Atxn1 1 0.38 0.78 0
31 INT235148 Positive_regulation of Binding of Atxn1 1 0.38 0.74 0
32 INT330881 Regulation of Inppl1 1 0.13 0 0
33 INT67335 Transcription of IGFBP5 1 0.37 0 0
34 INT233573 Negative_regulation of NKX3-1 1 0.42 1.49 0
35 INT235156 Phosphorylation of Atxn1 1 0.66 0.85 0
36 INT230382 Negative_regulation of Atxn1 1 0.20 0 0
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