GO:0045332

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Name phospholipid translocation
Categary Process
Go Slim No
Go Link GO:0045332
Unique Molecular Interactions 110
Total Molecular Interactions 131
Total Single Events 1167
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phospholipid translocation. They are ordered first by their pain relevance and then by number of times they were reported for phospholipid translocation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14
2 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
3 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
4 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
5 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
6 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
7 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
8 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
9 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
10 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
11 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
12 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
13 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
14 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
15 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
16 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
17 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
18 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
19 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
20 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
21 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
22 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
23 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
24 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
25 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
26 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
27 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
28 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24
29 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
30 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
31 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21
32 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
33 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21
34 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
35 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
36 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
37 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
38 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
39 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
40 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
41 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
42 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
43 INT115356 Binding of HLA-G and ATP8A1 1 0.00 0.52 0.15
44 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
45 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
46 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
47 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
48 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
49 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
50 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
51 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
52 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
53 INT74504 Binding of P2rx7 and Rp2 1 0.02 0.19 0.11
54 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
55 INT42224 ABCA1 Positive_regulation of CYBB 1 0.01 0 0.09
56 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
57 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
58 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09
59 INT42225 Binding of ABCA1 and DECR1 1 0.02 0 0.08
60 INT243156 Positive_regulation of P2rx7 Positive_regulation of NOS1 1 0.00 0.08 0.08
61 INT270829 P2rx7 Positive_regulation of Panx1 1 0.66 0.08 0.08
62 INT340420 Hmmr Regulation of P2rx7 1 0.01 1.12 0.08
63 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07
64 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07
65 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
66 INT293233 IDO1 Positive_regulation of ABCA1 1 0.01 0 0.06
67 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05
68 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05
69 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05
70 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05
71 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 1 0.01 1 0.05
72 INT270825 P2rx7 Positive_regulation of Slc37a4 1 0.01 0 0.04
73 INT230136 OSBPL8 Regulation of Binding of ABCA1 1 0.07 0.17 0.03
74 INT207343 Negative_regulation of CPOX Negative_regulation of Gene_expression of ABCA1 1 0.09 0 0.03
75 INT284392 Binding of ABCA1 and Vegfa 1 0.00 0.71 0
76 INT229927 CD59 Negative_regulation of Binding of ABCA1 1 0.01 0 0
77 INT229923 Binding of ABCA1 and C9 1 0.00 0.74 0
78 INT284372 Binding of ABCA1 and AMT 1 0.00 0 0
79 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0
80 INT217031 Binding of P2rx7 and Positive_regulation of Casp1 1 0.02 0 0
81 INT297056 Binding of ABCA1 and Oas1b 1 0.00 0.13 0
82 INT117795 ABCA1 Regulation of GHRL 1 0.00 0 0
83 INT284393 Positive_regulation of Binding of ABCA1 and Vegfa 1 0.00 0.36 0
84 INT326085 Prkaca Regulation of Phosphorylation of ABCA1 1 0.02 0.44 0
85 INT217032 Binding of P2rx7 and Positive_regulation of Il1 1 0.02 0 0
86 INT229981 Binding of ABCA1 and Cdca3 1 0.00 0.74 0
87 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0
88 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0
89 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
90 INT307283 Binding of ABCA1 and PMP2 1 0.00 0 0
91 INT326084 Prkaca Positive_regulation of Phosphorylation of ABCA1 1 0.06 0.44 0
92 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
93 INT216942 Positive_regulation of P2rx7 Positive_regulation of Casp1 1 0.14 0 0
94 INT307460 P2rx7 Positive_regulation of Phosphorylation of Gsk3a 1 0.02 0 0
95 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0
96 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phospholipid translocation. They are ordered first by their pain relevance and then by number of times they were reported in phospholipid translocation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
2 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
3 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
4 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
5 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
6 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
7 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
8 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
9 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
10 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
11 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
12 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
13 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
14 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
15 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
16 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
17 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
18 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
19 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
20 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
21 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
22 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
23 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
24 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
25 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
26 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
27 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
28 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
29 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
30 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
31 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
32 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
33 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
34 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
35 INT190089 Binding of Abca1 5 0.36 2.21 0.83
36 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
37 INT164627 Positive_regulation of Gene_expression of ABCA1 9 0.61 3.95 0.67
38 INT125734 Negative_regulation of Transcription of P2rx7 1 0.38 0.81 0.67
39 INT185485 Negative_regulation of Localization of P2rx7 1 0.26 0.95 0.62
40 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56
41 INT153099 Negative_regulation of Positive_regulation of P2rx7 1 0.42 0.25 0.5
42 INT215732 Negative_regulation of Binding of P2rx7 1 0.11 0.74 0.49
43 INT278114 Negative_regulation of Negative_regulation of P2rx7 1 0.21 0 0.45
44 INT167468 Regulation of Gene_expression of ABCA1 5 0.52 0.08 0.43
45 INT215741 Positive_regulation of Transcription of P2rx7 1 0.15 1.15 0.43
46 INT209180 Transcription of ABCA1 4 0.47 1.09 0.39
47 INT345322 Regulation of Transcription of ABCA1 1 0.01 0 0.39
48 INT167122 Protein_catabolism of ABCA1 3 0.02 0.27 0.37
49 INT239295 Positive_regulation of Abca1 3 0.30 2.18 0.32
50 INT121239 Regulation of Positive_regulation of P2rx7 2 0.61 1.32 0.32
51 INT216937 Regulation of Binding of P2rx7 1 0.44 0.08 0.29
52 INT239279 Regulation of Gene_expression of Abca1 2 0.44 2.42 0.26
53 INT344685 Positive_regulation of Binding of Abca1 1 0.12 0.76 0.26
54 INT284385 Positive_regulation of Localization of ABCA1 2 0.02 0.22 0.25
55 INT216938 Negative_regulation of Localization of P2rx7 1 0.37 0.25 0.24
56 INT239287 Transcription of Abca1 1 0.32 1.87 0.21
57 INT216940 Negative_regulation of Binding of P2rx7 1 0.37 0.15 0.2
58 INT300227 Positive_regulation of Binding of ABCA1 1 0.41 1.85 0.19
59 INT277709 Regulation of Binding of ABCA1 1 0.04 0.52 0.19
60 INT239308 Positive_regulation of Transcription of Abca1 1 0.28 0.67 0.18
61 INT216889 Phosphorylation of P2rx7 1 0.23 0 0.18
62 INT307467 Regulation of Binding of P2rx7 1 0.08 0 0.16
63 INT276766 Negative_regulation of ATP8A1 1 0.01 1.76 0.16
64 INT217387 Regulation of Abca1 3 0.27 2.01 0.15
65 INT270813 Positive_regulation of Localization of P2rx7 1 0.46 0.24 0.15
66 INT115357 Positive_regulation of ATP8A1 1 0.01 0.55 0.1
67 INT114084 Binding of ATP8A1 1 0.01 0.42 0.1
68 INT42227 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0 0.09
69 INT42226 Positive_regulation of Positive_regulation of ABCA1 1 0.02 0 0.09
70 INT307481 Phosphorylation of P2rx7 1 0.15 0.35 0.08
71 INT307480 Positive_regulation of Phosphorylation of P2rx7 1 0.09 0.35 0.08
72 INT262061 Negative_regulation of Gene_expression of Abca1 1 0.19 0.68 0.08
73 INT239296 Negative_regulation of Abca1 3 0.26 3.83 0.04
74 INT253595 Localization of Abca1 2 0.37 0.35 0.03
75 INT326077 Positive_regulation of Transcription of ABCA1 1 0.41 0.22 0
76 INT326076 Phosphorylation of ABCA1 1 0.73 0.66 0
77 INT326083 Positive_regulation of Phosphorylation of ABCA1 1 0.61 0.66 0
78 INT83729 Gene_expression of ATP8A1 1 0.01 0 0
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