GO:0045509

Name interleukin-27 receptor activity Categary Function Go Slim No Go Link GO:0045509

Unique Molecular Interactions 13 Total Molecular Interactions 23 Total Single Events 65 Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interleukin-27 receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for interleukin-27 receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT206074	Binding of IL6 and IL6ST	7	0.32	3.79	1.01
2	INT285562	Binding of Il27ra and Il27	1	0.10	2.19	0.67
3	INT172096	Binding of HLA-E and Il27ra	2	0.01	1.32	0.48
4	INT172094	Binding of Atp9a and Il27ra	1	0.01	0.98	0.4
5	INT94474	Binding of Cd3e and Il27ra	1	0.02	0	0.34
6	INT188200	IL6ST Positive_regulation of STAT3	1	0.25	0.38	0.23
7	INT226720	Binding of Prkca and Il27ra	1	0.00	0.52	0.2
8	INT226756	Positive_regulation of Binding of Prkca and Il27ra	1	0.00	0.52	0.2
9	INT258399	Binding of IL6R and IL6ST	1	0.06	0.61	0.18
10	INT128221	Binding of IL6ST and Il6	2	0.00	0.73	0.17
11	INT206081	IL6ST Negative_regulation of IL6	1	0.11	0.81	0.17
12	INT188470	Binding of Gpi1 and Il27ra	1	0.00	0.86	0.16
13	INT294316	IL6ST Positive_regulation of Gene_expression of IL11	1	0.22	0	0

Single Events

The table below shows the top 100 pain related interactions that have been reported for interleukin-27 receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in interleukin-27 receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT172186	Gene_expression of IL6ST	20	0.75	11.63	2.67
2	INT50994	Binding of Il27ra	5	0.11	1.77	2.15
3	INT133422	Binding of IL6ST	10	0.40	4.9	1.49
4	INT75923	Positive_regulation of IL6ST	5	0.45	2.49	1.21
5	INT231793	Negative_regulation of Il27ra	4	0.08	3.04	0.98
6	INT188230	Negative_regulation of IL6ST	3	0.33	0.49	0.45
7	INT239027	Regulation of Regulation of Il27ra	1	0.02	1.03	0.41
8	INT239031	Regulation of Il27ra	1	0.05	1.03	0.41
9	INT174433	Gene_expression of Il27ra	1	0.06	1.21	0.41
10	INT136518	Regulation of IL6ST	2	0.29	0.31	0.36
11	INT136520	Positive_regulation of Regulation of IL6ST	1	0.09	0.08	0.13
12	INT254238	Positive_regulation of Il27ra	3	0.06	0.93	0.12
13	INT206151	Positive_regulation of Gene_expression of IL6ST	2	0.24	0.35	0.06
14	INT294329	Regulation of Gene_expression of IL6ST	1	0.22	0	0.05
15	INT294344	Localization of IL6ST	1	0.39	0	0.04
16	INT206153	Phosphorylation of IL6ST	1	0.22	0.05	0
17	INT206156	Positive_regulation of Phosphorylation of IL6ST	1	0.14	0.05	0