GO:0045509

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Latest revision as of 00:21, 22 January 2013

Name interleukin-27 receptor activity
Categary Function
Go Slim No
Go Link GO:0045509
Unique Molecular Interactions 13
Total Molecular Interactions 23
Total Single Events 65
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

[edit] Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interleukin-27 receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for interleukin-27 receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
2 INT285562 Binding of Il27ra and Il27 1 0.10 2.19 0.67
3 INT172096 Binding of HLA-E and Il27ra 2 0.01 1.32 0.48
4 INT172094 Binding of Atp9a and Il27ra 1 0.01 0.98 0.4
5 INT94474 Binding of Cd3e and Il27ra 1 0.02 0 0.34
6 INT188200 IL6ST Positive_regulation of STAT3 1 0.25 0.38 0.23
7 INT226720 Binding of Prkca and Il27ra 1 0.00 0.52 0.2
8 INT226756 Positive_regulation of Binding of Prkca and Il27ra 1 0.00 0.52 0.2
9 INT258399 Binding of IL6R and IL6ST 1 0.06 0.61 0.18
10 INT128221 Binding of IL6ST and Il6 2 0.00 0.73 0.17
11 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17
12 INT188470 Binding of Gpi1 and Il27ra 1 0.00 0.86 0.16
13 INT294316 IL6ST Positive_regulation of Gene_expression of IL11 1 0.22 0 0

[edit] Single Events

The table below shows the top 100 pain related interactions that have been reported for interleukin-27 receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in interleukin-27 receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT172186 Gene_expression of IL6ST 20 0.75 11.63 2.67
2 INT50994 Binding of Il27ra 5 0.11 1.77 2.15
3 INT133422 Binding of IL6ST 10 0.40 4.9 1.49
4 INT75923 Positive_regulation of IL6ST 5 0.45 2.49 1.21
5 INT231793 Negative_regulation of Il27ra 4 0.08 3.04 0.98
6 INT188230 Negative_regulation of IL6ST 3 0.33 0.49 0.45
7 INT239027 Regulation of Regulation of Il27ra 1 0.02 1.03 0.41
8 INT239031 Regulation of Il27ra 1 0.05 1.03 0.41
9 INT174433 Gene_expression of Il27ra 1 0.06 1.21 0.41
10 INT136518 Regulation of IL6ST 2 0.29 0.31 0.36
11 INT136520 Positive_regulation of Regulation of IL6ST 1 0.09 0.08 0.13
12 INT254238 Positive_regulation of Il27ra 3 0.06 0.93 0.12
13 INT206151 Positive_regulation of Gene_expression of IL6ST 2 0.24 0.35 0.06
14 INT294329 Regulation of Gene_expression of IL6ST 1 0.22 0 0.05
15 INT294344 Localization of IL6ST 1 0.39 0 0.04
16 INT206153 Phosphorylation of IL6ST 1 0.22 0.05 0
17 INT206156 Positive_regulation of Phosphorylation of IL6ST 1 0.14 0.05 0
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