GO:0045604

Name regulation of epidermal cell differentiation Categary Process Go Slim No Go Link GO:0045604

Unique Molecular Interactions 34 Total Molecular Interactions 79 Total Single Events 250 Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of epidermal cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of epidermal cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT101810	Binding of NFE2L2 and KEAP1	7	0.53	4.12	0.29
2	INT101813	KEAP1 Negative_regulation of NFE2L2	3	0.47	1.63	0.28
3	INT101812	Binding of KEAP1 and Positive_regulation of Gene_expression of GCLC	1	0.54	0.1	0.19
4	INT319663	Binding of Nfe2l2 and Keap1	1	0.40	2.83	0.17
5	INT319680	Keap1 Negative_regulation of Positive_regulation of Nfe2l2	1	0.36	0.93	0.17
6	INT313308	Binding of SQSTM1 and KEAP1	1	0.46	1.16	0.1
7	INT313301	SQSTM1 Regulation of Protein_catabolism of KEAP1	1	0.43	0.58	0.1
8	INT319672	Nfe2l2 Regulation of Binding of Keap1	1	0.23	0.46	0.09
9	INT131598	Keap1 Negative_regulation of Nfe2l2	2	0.65	1.27	0.08
10	INT101807	Gene_expression of KEAP1 Negative_regulation of Positive_regulation of GCLC	1	0.46	0	0.08
11	INT197545	KEAP1 Regulation of NFE2L2	3	0.49	0.8	0
12	INT315265	Eri1 Negative_regulation of Keap1	1	0.01	0.26	0
13	INT319668	Keap1 Regulation of Nfe2l2	1	0.52	0.84	0
14	INT313293	Binding of KEAP1 and GOPC	1	0.04	0.24	0
15	INT313298	Negative_regulation of SQSTM1 Positive_regulation of KEAP1	1	0.39	0.39	0
16	INT315262	Negative_regulation of Keap1 Negative_regulation of Gene_expression of Nfe2l2	1	0.30	0.48	0
17	INT315260	Eri1 Regulation of Keap1	1	0.00	0.48	0
18	INT246061	KEAP1 Regulation of Positive_regulation of NFE2L2	1	0.34	0	0
19	INT246058	Binding of KEAP1 and Positive_regulation of NFE2L2	1	0.38	0	0
20	INT319692	Binding of Keap1 and Gadd45gip1	1	0.35	0.18	0
21	INT315270	Rela Positive_regulation of Negative_regulation of Keap1	1	0.10	0.63	0
22	INT319670	Negative_regulation of Binding of Nfe2l2 and Keap1	1	0.36	0.44	0
23	INT215414	KEAP1 Regulation of Regulation of NFE2L2	1	0.02	0.19	0
24	INT313299	Negative_regulation of Binding of NFE2L2 and KEAP1	1	0.24	0.14	0
25	INT197544	Binding of KEAP1 and KLHL2	1	0.02	0.43	0
26	INT319662	Gadd45gip1 Negative_regulation of Keap1	1	0.42	0.66	0
27	INT197547	Binding of PTS and KEAP1	1	0.08	1.23	0
28	INT313296	Binding of KEAP1 and PGAM5	1	0.11	0.15	0
29	INT319669	Binding of Keap1 and Gopc	1	0.08	0	0
30	INT319676	Gadd45gip1 Regulation of Keap1	1	0.27	0.36	0
31	INT313310	KEAP1 Regulation of Gene_expression of SQSTM1	1	0.43	0.35	0
32	INT313311	SQSTM1 Positive_regulation of Positive_regulation of KEAP1	1	0.45	0	0
33	INT313306	KEAP1 Positive_regulation of SPARC	1	0.02	0.37	0
34	INT313294	Negative_regulation of SQSTM1 Positive_regulation of Positive_regulation of KEAP1	1	0.39	0	0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of epidermal cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of epidermal cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT154654	Positive_regulation of Keap1	4	0.68	1.55	0.82
2	INT167742	Negative_regulation of Keap1	14	0.55	9.16	0.63
3	INT131597	Gene_expression of Keap1	17	0.76	6.65	0.55
4	INT101815	Binding of KEAP1	6	0.44	5.29	0.39
5	INT154653	Negative_regulation of Positive_regulation of Keap1	2	0.36	0.59	0.34
6	INT101821	Localization of KEAP1	4	0.71	0.93	0.28
7	INT167737	Positive_regulation of Negative_regulation of Keap1	2	0.47	1.6	0.27
8	INT154656	Regulation of Keap1	2	0.46	1.9	0.25
9	INT315230	Binding of Keap1	5	0.43	3.91	0.23
10	INT197575	Protein_catabolism of KEAP1	4	0.91	3.44	0.23
11	INT101820	Negative_regulation of KEAP1	20	0.58	18.79	0.19
12	INT131596	Positive_regulation of Gene_expression of Keap1	6	0.52	2.09	0.16
13	INT101831	Gene_expression of KEAP1	21	0.77	10.82	0.12
14	INT197563	Regulation of KEAP1	10	0.56	3.18	0.11
15	INT313329	Positive_regulation of Binding of KEAP1	1	0.46	0.44	0.11
16	INT167741	Localization of Keap1	3	0.70	1.35	0.1
17	INT101824	Positive_regulation of Localization of KEAP1	2	0.57	0	0.09
18	INT101830	Negative_regulation of Localization of KEAP1	1	0.48	0	0.09
19	INT319632	Regulation of Binding of Keap1	1	0.40	0.45	0.09
20	INT197562	Positive_regulation of KEAP1	16	0.63	6.78	0.08
21	INT101827	Positive_regulation of Gene_expression of KEAP1	5	0.69	2.67	0.08
22	INT319614	Protein_catabolism of Keap1	1	0.89	0.28	0.07
23	INT197560	Negative_regulation of Gene_expression of KEAP1	5	0.58	3.12	0
24	INT315237	Negative_regulation of Gene_expression of Keap1	4	0.38	1.55	0
25	INT315240	Regulation of Gene_expression of Keap1	3	0.40	1.03	0
26	INT315231	Negative_regulation of Binding of Keap1	2	0.38	0.42	0
27	INT315238	Negative_regulation of Regulation of Keap1	1	0.32	0.68	0
28	INT315222	Transcription of Keap1	1	0.52	0.6	0
29	INT315227	Regulation of Regulation of Keap1	1	0.34	0.61	0
30	INT313325	Regulation of Gene_expression of KEAP1	1	0.41	0	0
31	INT197556	Positive_regulation of Protein_catabolism of KEAP1	1	0.50	0.74	0
32	INT197574	Positive_regulation of Negative_regulation of KEAP1	1	0.50	1.15	0
33	INT315233	Regulation of Negative_regulation of Keap1	1	0.34	0.49	0
34	INT319639	Positive_regulation of Binding of Keap1	1	0.45	0.06	0
35	INT315234	Negative_regulation of Negative_regulation of Keap1	1	0.32	0.48	0
36	INT313316	Regulation of Positive_regulation of KEAP1	1	0.41	0	0
37	INT197555	Transcription of KEAP1	1	0.71	2.33	0
38	INT315225	Positive_regulation of Transcription of Keap1	1	0.38	0.26	0
39	INT197570	Negative_regulation of Transcription of KEAP1	1	0.58	1.19	0
40	INT313317	Positive_regulation of Positive_regulation of KEAP1	1	0.46	0	0