GO:0045786

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Name negative regulation of cell cycle
Categary Process
Go Slim No
Go Link GO:0045786
Unique Molecular Interactions 749
Total Molecular Interactions 992
Total Single Events 8207
Pain Genes Associated 51

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
2 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
3 INT108473 Binding of ADCYAP1 and PNOC 1 0.32 0.64 3.41
4 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
5 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
6 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
7 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
8 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
9 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
10 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
11 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
12 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
13 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
14 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
15 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
16 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
17 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
18 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73
19 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
20 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
21 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
22 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 0.01 1.65 1.6
23 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
24 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
25 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
26 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
27 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
28 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
29 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
30 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
31 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
32 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43
33 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
34 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
35 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
36 INT181492 NGF Regulation of TRPV1 1 0.21 0.93 1.31
37 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
38 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
39 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
40 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
41 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
42 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
43 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
44 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
45 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
46 INT298260 Binding of Runx3 and Pou4f1 1 0.52 2.08 1.22
47 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
48 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
49 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
50 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
51 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
52 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
53 INT147446 ADCYAP1 Regulation of Localization of CP 1 0.02 1.12 1.16
54 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
55 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
56 INT147448 ADCYAP1 Regulation of Localization of NFKB1 1 0.47 1.12 1.15
57 INT160540 Binding of NGF and PSIP1 2 0.29 1.43 1.12
58 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
59 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
60 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
61 INT298292 Runx3 Positive_regulation of Gene_expression of Ntrk3 1 0.35 1.36 1.09
62 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
63 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
64 INT181494 TRPV3 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
65 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
66 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
67 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
68 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
69 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
70 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
71 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
72 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
73 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1
74 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
75 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
76 INT127672 Binding of NGFR and NTRK1 1 0.17 2.28 0.97
77 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
78 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
79 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
80 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
81 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
82 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
83 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
84 INT271409 NGF Positive_regulation of TRPV1 1 0.08 2.45 0.94
85 INT271410 NGF Positive_regulation of Gene_expression of TRPV1 1 0.07 2.45 0.94
86 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
87 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
88 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
89 INT127673 NGF Regulation of Gene_expression of NTRK1 1 0.48 2.12 0.92
90 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
91 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
92 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
93 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
94 INT165540 NGF Positive_regulation of GRIN1 1 0.07 0.17 0.88
95 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
96 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
97 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
98 INT120825 Adcyap1 Positive_regulation of Localization of Nos1 1 0.26 0.62 0.85
99 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85
100 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
101 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
102 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
103 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
104 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
105 INT63594 Snai1 Negative_regulation of Binding of Ugt1a2 1 0.05 0.32 0.82
106 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
107 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
108 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
109 INT63596 Snai1 Negative_regulation of ITS 1 0.00 0.31 0.81
110 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
111 INT298279 Pou4f1 Positive_regulation of Gene_expression of Runx3 1 0.50 1.31 0.81
112 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79
113 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
114 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
115 INT142208 Adcyap1 Positive_regulation of Transcription of Gh 1 0.05 0 0.77
116 INT142210 Adcyap1 Positive_regulation of Gh 1 0.05 0 0.77
117 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
118 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
119 INT307044 Tmie Regulation of Casp3 1 0.01 0 0.75
120 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
121 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73
122 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
123 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
124 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71
125 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
126 INT118979 NGF Positive_regulation of Phosphorylation of NTRK1 1 0.56 0.67 0.67
127 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
128 INT74468 Adcyap1 Positive_regulation of Localization of Gnrhr 1 0.27 0 0.67
129 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
130 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
131 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
132 INT142209 Adcyap1 Positive_regulation of Gene_expression of Gh 1 0.05 0 0.63
133 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
134 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62
135 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
136 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
137 INT114505 Negative_regulation of Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
138 INT114506 Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
139 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
140 INT163376 RYBP Positive_regulation of Gene_expression of Casp3 2 0.01 0.57 0.59
141 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
142 INT137247 Slc6a14 Negative_regulation of Ptgs2 2 0.19 1.38 0.58
143 INT137248 Slc6a14 Negative_regulation of Gene_expression of Ptgs2 1 0.19 1.32 0.58
144 INT103165 NGF Positive_regulation of Localization of INS 1 0.05 0 0.58
145 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
146 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
147 INT59155 Binding of Adcyap1 and Vip 2 0.34 0.08 0.55
148 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
149 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
150 INT112399 Olr897-ps Regulation of Gene_expression of Casp3 1 0.03 0 0.54
151 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
152 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
153 INT142206 Negative_regulation of Adcyap1 Positive_regulation of Gh 1 0.04 0 0.54
154 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
155 INT245558 Runx3 Regulation of Ngfr 1 0.06 1 0.53
156 INT69882 Ptger2 Positive_regulation of Gene_expression of Ptgs2 1 0.19 0.6 0.52
157 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
158 INT116541 Binding of Ptgs2 and ZNF398 1 0.00 0.68 0.52
159 INT74517 Binding of Casp3 and Cnrip1 1 0.31 0 0.51
160 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
161 INT97483 ADCYAP1 Positive_regulation of Localization of SST 1 0.04 0 0.5
162 INT127677 NGF Regulation of Gene_expression of NGFR 1 0.20 1.11 0.5
163 INT230533 LILRB1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.5
164 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
165 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
166 INT106662 Adcyap1 Regulation of Penk 1 0.00 0 0.49
167 INT106664 Adcyap1 Regulation of Gene_expression of Vip 1 0.00 0 0.49
168 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
169 INT97482 ADCYAP1 Positive_regulation of Localization of VIP 1 0.50 0 0.49
170 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
171 INT106663 Adcyap1 Regulation of Vip 1 0.00 0 0.49
172 INT97484 Binding of ADCYAP1 and GRP 1 0.26 0 0.48
173 INT97487 ADCYAP1 Positive_regulation of Tac1 1 0.02 0 0.48
174 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48
175 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48
176 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47
177 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
178 INT307048 Cnr1 Positive_regulation of Casp3 1 0.08 0 0.47
179 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
180 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
181 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
182 INT20761 INHBA Regulation of Localization of GNRH1 1 0.02 0 0.46
183 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
184 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
185 INT298284 Runx3 Negative_regulation of Gene_expression of Ntrk1 1 0.26 0.39 0.43
186 INT201092 Binding of KNG1 and NGF 1 0.00 0.31 0.43
187 INT298291 Runx3 Negative_regulation of Gene_expression of Ntrk3 1 0.32 0.4 0.43
188 INT127676 NGF Regulation of TNFRSF1B 1 0.21 1.02 0.42
189 INT80824 NGF Positive_regulation of NTF3 1 0.47 0.26 0.42
190 INT127675 NGF Regulation of NTRK1 1 0.48 1.01 0.42
191 INT127674 NGF Regulation of Gene_expression of TNFRSF1B 1 0.48 1.02 0.42
192 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
193 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41
194 INT298286 Runx3 Regulation of Gene_expression of Runx1 1 0.47 0.36 0.41
195 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
196 INT350698 Mir326 Regulation of Ets1 1 0.01 1.27 0.4
197 INT298259 Pou4f1 Negative_regulation of Gene_expression of Runx3 1 0.46 0.58 0.4
198 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4
199 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
200 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
3 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
4 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
5 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
6 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
7 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
8 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
9 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
10 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
11 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
12 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
13 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
14 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11
15 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
16 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
17 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
18 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
19 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
20 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
21 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
22 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38
23 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
24 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
25 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
26 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
27 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
28 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
29 INT54077 Gene_expression of Adcyap1 62 0.78 23.17 16.75
30 INT20216 Localization of NGF 40 0.80 18.16 16.61
31 INT84924 Positive_regulation of Gene_expression of NGF 29 0.68 17.91 16.46
32 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
33 INT71150 Binding of NGF 22 0.46 13.67 14.81
34 INT58896 Localization of Adcyap1 35 0.81 4.57 14.77
35 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
36 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44
37 INT48259 Positive_regulation of Adcyap1 33 0.67 10.94 14.39
38 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14
39 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
40 INT203490 Gene_expression of Runx3 19 0.76 27.56 12.57
41 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
42 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39
43 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
44 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
45 INT85048 Regulation of NGF 19 0.62 11.61 10.5
46 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
47 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
48 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39
49 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
50 INT147452 Gene_expression of ADCYAP1 14 0.77 12.54 9.28
51 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
52 INT106199 Positive_regulation of Adcyap1 32 0.68 13.68 9.14
53 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
54 INT1223 Negative_regulation of Snai1 15 0.38 2.05 8.46
55 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
56 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37
57 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
58 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
59 INT52116 Regulation of Adcyap1 20 0.53 6.1 8.14
60 INT98178 Localization of Casp3 32 0.65 21.01 7.77
61 INT20914 Positive_regulation of Snai1 13 0.41 3.41 7.69
62 INT65964 Regulation of Adcyap1 13 0.45 10.1 7.54
63 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
64 INT63373 Negative_regulation of Gene_expression of NGF 14 0.57 8.9 7.1
65 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
66 INT63374 Regulation of Gene_expression of NGF 12 0.45 5.6 6.4
67 INT57232 Binding of Casp3 22 0.36 9.42 6.2
68 INT43224 Negative_regulation of Adcyap1 17 0.54 3.69 6.19
69 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
70 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
71 INT333909 Positive_regulation of Gene_expression of HDAC1 1 0.44 14.15 5.9
72 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86
73 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71
74 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
75 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
76 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
77 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
78 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
79 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
80 INT152742 Positive_regulation of Localization of NGF 7 0.50 4.44 5.02
81 INT96492 Gene_expression of NGFR 24 0.00 12.3 4.59
82 INT66048 Positive_regulation of Gene_expression of Adcyap1 5 0.49 8.21 4.52
83 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
84 INT106548 Localization of Adcyap1 14 0.80 5.05 4.33
85 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
86 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
87 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
88 INT138209 Positive_regulation of Localization of Adcyap1 2 0.41 2.07 4.08
89 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
90 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
91 INT115773 Negative_regulation of Localization of Ptgs2 6 0.43 2.99 3.81
92 INT115877 Negative_regulation of Adcyap1 14 0.59 5.31 3.74
93 INT59154 Binding of Adcyap1 12 0.48 4.16 3.71
94 INT84925 Transcription of NGF 11 0.65 4.13 3.65
95 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
96 INT53200 Binding of Ptgs2 11 0.48 5.08 3.54
97 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
98 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
99 INT58897 Regulation of Localization of Adcyap1 4 0.45 1.82 3.48
100 INT12385 Localization of NGFR 6 0.81 3.05 3.47
101 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
102 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
103 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
104 INT127111 Regulation of Inhba 5 0.60 2.85 3.28
105 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
106 INT120823 Positive_regulation of Gene_expression of Adcyap1 10 0.68 6.71 3.22
107 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
108 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
109 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
110 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
111 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
112 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
113 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
114 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
115 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
116 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
117 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
118 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
119 INT1225 Regulation of Snai1 10 0.30 1.05 2.72
120 INT54938 Regulation of Rb1 6 0.44 4.41 2.69
121 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
122 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
123 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
124 INT127176 Transcription of Ptgs2 8 0.58 4.68 2.58
125 INT203441 Positive_regulation of Gene_expression of Runx3 4 0.66 4.35 2.49
126 INT127108 Gene_expression of Inhba 12 0.65 3.21 2.48
127 INT59119 Positive_regulation of ADCYAP1 9 0.69 4.68 2.48
128 INT17846 Binding of Ptgs2 8 0.32 4.66 2.48
129 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
130 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
131 INT86147 Positive_regulation of Inhba 8 0.63 1.94 2.39
132 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
133 INT97485 Localization of ADCYAP1 4 0.78 0.24 2.35
134 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
135 INT31118 Localization of Casp3 17 0.73 11.55 2.3
136 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
137 INT78958 Regulation of Negative_regulation of Ptgs2 6 0.42 2.61 2.3
138 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
139 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
140 INT147453 Positive_regulation of Gene_expression of ADCYAP1 3 0.69 3.49 2.1
141 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
142 INT63375 Positive_regulation of Positive_regulation of NGF 2 0.48 1.17 2.08
143 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04
144 INT147451 Regulation of Gene_expression of ADCYAP1 3 0.61 1.88 2.04
145 INT54076 Transcription of Adcyap1 4 0.67 1.65 1.98
146 INT99970 Regulation of Binding of NGF 2 0.27 2.35 1.93
147 INT77805 Regulation of Gene_expression of Ptgs2 6 0.51 2.7 1.92
148 INT52691 Positive_regulation of Transcription of Ptgs2 5 0.44 3 1.9
149 INT77300 Negative_regulation of Positive_regulation of Adcyap1 3 0.35 0 1.88
150 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
151 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
152 INT66047 Regulation of Gene_expression of Adcyap1 2 0.58 3.36 1.84
153 INT240058 Gene_expression of RHOB 2 0.55 4.29 1.84
154 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
155 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
156 INT32024 Positive_regulation of Positive_regulation of Snai1 2 0.25 0.32 1.7
157 INT57971 Regulation of Rb1 5 0.41 2.36 1.66
158 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
159 INT102532 Protein_catabolism of Casp3 24 0.64 16.78 1.64
160 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
161 INT55302 Binding of Snai1 2 0.31 1.94 1.63
162 INT240059 Binding of RHOB 7 0.48 3.96 1.59
163 INT127110 Transcription of Inhba 3 0.58 1.44 1.59
164 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
165 INT245537 Negative_regulation of Runx3 4 0.56 4 1.53
166 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
167 INT8707 Localization of LILRB1 2 0.60 1.5 1.5
168 INT106749 Negative_regulation of Negative_regulation of Casp3 6 0.34 5.12 1.48
169 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
170 INT149622 Positive_regulation of Transcription of Ptgs2 3 0.28 2.48 1.46
171 INT298250 Negative_regulation of Gene_expression of Runx3 1 0.56 1.92 1.45
172 INT140843 Regulation of Phosphorylation of Casp3 1 0.25 0.37 1.44
173 INT127679 Positive_regulation of Gene_expression of NGFR 7 0.67 4.98 1.43
174 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
175 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
176 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
177 INT202035 Gene_expression of LILRB1 5 0.75 4.78 1.41
178 INT116008 Binding of Gata3 2 0.34 1.37 1.41
179 INT190768 Regulation of Positive_regulation of Ptgs2 1 0.04 1.2 1.41
180 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
181 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
182 INT109222 Positive_regulation of Negative_regulation of Cdk5 2 0.50 0.23 1.39
183 INT159303 Regulation of Negative_regulation of NGF 1 0.44 0.96 1.39
184 INT220073 Negative_regulation of Binding of NGF 1 0.23 1.1 1.39
185 INT158709 Negative_regulation of Phosphorylation of Cdk5 1 0.40 0 1.39
186 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38
187 INT59153 Positive_regulation of Binding of Adcyap1 3 0.43 0.56 1.37
188 INT333914 Transcription of HDAC1 1 0.34 3.04 1.37
189 INT171690 Transcription of Casp3 8 0.55 2.62 1.36
190 INT97943 Positive_regulation of Protein_catabolism of Casp3 7 0.28 7.4 1.35
191 INT135658 Phosphorylation of Ptgs2 2 0.23 1.39 1.34
192 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32
193 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
194 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
195 INT137811 Negative_regulation of NGFR 4 0.50 2.22 1.28
196 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
197 INT56127 Positive_regulation of NGFR 8 0.49 5.3 1.27
198 INT101026 Positive_regulation of Negative_regulation of Ptgs2 2 0.35 1.01 1.23
199 INT41124 Negative_regulation of Rb1 11 0.44 3.17 1.22
200 INT12386 Binding of NGFR 6 0.48 2.15 1.22
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