GO:0045835

Name negative regulation of meiosis Categary Process Go Slim No Go Link GO:0045835

Unique Molecular Interactions 91 Total Molecular Interactions 125 Total Single Events 346 Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of meiosis. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of meiosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT203149	Binding of Mif and Osm	1	0.02	2.93	1.78
2	INT8416	LIF Regulation of TAC1	1	0.13	0.36	1.04
3	INT8415	LIF Regulation of VIP	1	0.13	0.36	1.04
4	INT56743	LIF Positive_regulation of Cck	1	0.08	0.18	1.02
5	INT56742	LIF Positive_regulation of Chat	1	0.02	0.2	0.98
6	INT188196	LIF Regulation of MAPK1	1	0.21	2.26	0.87
7	INT188214	OSM Regulation of MAPK1	1	0.20	2.27	0.87
8	INT98479	Lif Regulation of Gene_expression of Grin1	1	0.04	0.35	0.82
9	INT149597	Lif Regulation of Regulation of Gal	1	0.30	0.69	0.73
10	INT149596	Lif Negative_regulation of Negative_regulation of Gal	1	0.10	0.5	0.7
11	INT82267	Lif Regulation of Gene_expression of Gal	1	0.40	2.76	0.62
12	INT149595	Lif Negative_regulation of Negative_regulation of Trpv1	1	0.34	0.44	0.61
13	INT333967	Binding of Osm and Sgp158	1	0.00	0.92	0.56
14	INT8440	Cntf Regulation of LIF	1	0.33	0.18	0.52
15	INT98480	Lif Positive_regulation of Pnoc	1	0.18	0.2	0.49
16	INT98484	Lif Regulation of Gene_expression of Gal	1	0.04	0.16	0.47
17	INT98482	Lif Positive_regulation of Gene_expression of Pnoc	1	0.16	0.17	0.46
18	INT98481	Lif Regulation of Regulation of Oprl1	1	0.04	0.16	0.45
19	INT188194	OSM Regulation of IL6	1	0.16	1.12	0.43
20	INT188205	OSM Regulation of LIF	1	0.09	1.12	0.43
21	INT188207	LIF Regulation of IL6	1	0.17	1.12	0.43
22	INT162043	F2 Positive_regulation of Gene_expression of OSM	1	0.44	1.13	0.41
23	INT91719	Binding of BDNF and LIF	1	0.09	1.65	0.38
24	INT354790	MMP3 Negative_regulation of Gene_expression of OSM	1	0.00	0.27	0.31
25	INT162042	F2 Regulation of OSM	1	0.17	1.17	0.31
26	INT162039	F2 Regulation of Gene_expression of OSM	1	0.29	0.94	0.29
27	INT188209	OSM Positive_regulation of MAPK1	1	0.35	0.47	0.27
28	INT188203	EGF Positive_regulation of Protein_catabolism of OSM	1	0.30	0.17	0.21
29	INT188201	OSM Positive_regulation of Phosphorylation of STAT3	1	0.40	0.24	0.21
30	INT82268	Lif Regulation of Gene_expression of Iapp	1	0.06	0.9	0.2
31	INT222426	Lif Positive_regulation of Localization of Pomc	1	0.02	0.75	0.17
32	INT32211	POMC Positive_regulation of Gene_expression of Lif	1	0.01	0.61	0.15
33	INT188197	LIF Positive_regulation of STAT3	1	0.35	0.27	0.12
34	INT188198	OSM Positive_regulation of STAT3	1	0.52	0.24	0.12
35	INT294440	KLK4 Negative_regulation of LIF	1	0.00	0	0.1
36	INT138028	Binding of Osm and Il31	1	0.25	0.08	0.1
37	INT202409	Binding of Osm and Map3k3	1	0.20	0.13	0.09
38	INT202392	Binding of Osm and Nexn	1	0.02	0.13	0.09
39	INT202406	Binding of Osm and Mapk14	1	0.21	0.13	0.09
40	INT202400	Binding of Akt1 and Osm	1	0.05	0.13	0.09
41	INT202407	Binding of Osm and Racgap1	1	0.04	0.13	0.09
42	INT322851	Binding of KRIT1 and OSM	1	0.04	1.42	0.09
43	INT355019	Lif Positive_regulation of JAK1	1	0.00	0.69	0.08
44	INT322846	Binding of OSM and PDCD10	1	0.10	1.06	0.08
45	INT299539	Lif Positive_regulation of Phosphorylation of Stat3	1	0.08	0	0.08
46	INT355020	Lif Positive_regulation of SOAT1	1	0.02	0.7	0.08
47	INT355010	Lif Positive_regulation of Il6st	1	0.02	0.69	0.08
48	INT188210	EGF Positive_regulation of OSM	1	0.28	0	0.07
49	INT299548	Binding of TGFB1 and Lif	1	0.02	0	0.07
50	INT12987	LIF Regulation of Localization of Prl	1	0.09	0	0.07
51	INT299535	Binding of Egf and Lif	1	0.07	0	0.07
52	INT268652	Binding of CLDN4 and LIF	1	0.35	0.44	0.04
53	INT261388	Nsdhl Regulation of Lif	1	0.08	0.67	0.04
54	INT261377	Nsdhl Positive_regulation of Lif	1	0.08	0.6	0.03
55	INT266075	LIF Regulation of Gene_expression of PAEP	1	0.19	0.43	0.03
56	INT266070	LIF Regulation of Gene_expression of PAPPA	1	0.35	0.49	0.03
57	INT266072	LGALS1 Regulation of Gene_expression of LIF	1	0.17	0.43	0.03
58	INT266067	PAPPA Regulation of Gene_expression of LIF	1	0.35	0.49	0.03
59	INT266076	LIF Regulation of Gene_expression of LGALS1	1	0.17	0.43	0.03
60	INT66341	LIF Positive_regulation of Gene_expression of FOS	1	0.11	1.07	0
61	INT66339	LIF Positive_regulation of Phosphorylation of CLIP2	1	0.45	1.57	0
62	INT268651	NUPL2 Positive_regulation of Gene_expression of LIF	1	0.66	0.07	0
63	INT322847	Regulation of Binding of OSM and PDCD10	1	0.06	0	0
64	INT322875	Binding of OSM and Lyz2	1	0.00	0	0
65	INT297852	Nanos2 Positive_regulation of Positive_regulation of Gopc	1	0.07	0.1	0
66	INT66342	LIF Positive_regulation of Phosphorylation of CLIP1	1	0.60	1.57	0
67	INT297851	Nanos2 Regulation of Stra8	1	0.35	0.6	0
68	INT236171	Binding of LIF and Hmgcr	1	0.02	0	0
69	INT297853	Nanos2 Positive_regulation of Positive_regulation of Snord116	1	0.49	0.1	0
70	INT66353	LIF Regulation of Ctf2p	1	0.02	0.47	0
71	INT297846	Nanos2 Regulation of Dnmt3l	1	0.34	0.6	0
72	INT66340	LIF Positive_regulation of C1orf61	1	0.12	0.52	0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of meiosis. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of meiosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT2111	Gene_expression of LIF	34	0.77	16.82	6.76
2	INT32208	Gene_expression of Lif	23	0.74	6.23	3.7
3	INT81695	Gene_expression of OSM	14	0.75	7.29	3.58
4	INT82265	Gene_expression of Lif	7	0.50	6.17	3.4
5	INT76240	Positive_regulation of Lif	6	0.69	6.04	3.13
6	INT116798	Gene_expression of Osm	8	0.77	4.74	3.01
7	INT33895	Positive_regulation of LIF	9	0.67	2.47	2.34
8	INT138021	Positive_regulation of Gene_expression of Osm	2	0.43	3.04	2
9	INT44027	Positive_regulation of Lif	7	0.40	2.76	1.9
10	INT203135	Negative_regulation of Gene_expression of Osm	1	0.12	3.08	1.73
11	INT203129	Binding of Osm	1	0.10	2.78	1.72
12	INT253751	Localization of Lif	3	0.73	3.94	1.58
13	INT50437	Regulation of LIF	6	0.44	2.12	1.53
14	INT50436	Negative_regulation of Positive_regulation of LIF	1	0.37	0.33	1.42
15	INT34933	Positive_regulation of Gene_expression of LIF	6	0.67	3.41	1.38
16	INT173589	Localization of OSM	4	0.58	1.65	1.07
17	INT149594	Positive_regulation of Gene_expression of Lif	2	0.47	0.89	1
18	INT188232	Positive_regulation of OSM	7	0.41	1.57	0.94
19	INT162048	Regulation of OSM	4	0.43	3.3	0.94
20	INT102819	Regulation of Lif	8	0.53	2.05	0.87
21	INT98478	Negative_regulation of Lif	3	0.42	1.29	0.84
22	INT82262	Regulation of Lif	3	0.31	1.67	0.83
23	INT354449	Positive_regulation of Localization of Lif	1	0.33	1.24	0.83
24	INT68794	Negative_regulation of LIF	6	0.41	1.38	0.7
25	INT2109	Negative_regulation of Gene_expression of LIF	4	0.41	0.89	0.66
26	INT323909	Positive_regulation of Gene_expression of OSM	2	0.29	0.67	0.61
27	INT184456	Positive_regulation of Osm	3	0.24	1.41	0.54
28	INT216834	Localization of Lif	2	0.34	0.23	0.46
29	INT299516	Phosphorylation of Lif	1	0.26	0.56	0.46
30	INT2110	Localization of LIF	5	0.73	1.59	0.44
31	INT32207	Regulation of Gene_expression of Lif	3	0.19	1.01	0.42
32	INT162046	Negative_regulation of OSM	2	0.41	1.12	0.31
33	INT299519	Binding of Lif	2	0.21	0.67	0.29
34	INT264094	Localization of Osm	1	0.07	0.72	0.28
35	INT184437	Regulation of Osm	2	0.19	0.61	0.27
36	INT188220	Phosphorylation of OSM	6	0.59	0.69	0.24
37	INT188235	Phosphorylation of LIF	1	0.53	0.48	0.23
38	INT188236	Protein_catabolism of OSM	1	0.63	0.17	0.21
39	INT318610	Positive_regulation of Binding of Lif	1	0.28	0.67	0.19
40	INT188224	Regulation of Gene_expression of LIF	1	0.23	0.53	0.18
41	INT188216	Positive_regulation of Regulation of LIF	1	0.39	1.13	0.17
42	INT338147	Negative_regulation of Gene_expression of Lif	1	0.38	0.29	0.15
43	INT216451	Negative_regulation of Lif	1	0.36	0.77	0.15
44	INT333440	Protein_catabolism of Lif	1	0.23	0.2	0.08
45	INT216454	Binding of Lif	2	0.27	0.85	0.07
46	INT188233	Negative_regulation of Phosphorylation of OSM	1	0.31	0	0.07
47	INT299524	Positive_regulation of Localization of Lif	1	0.21	0	0.06
48	INT333439	Positive_regulation of Gene_expression of Lif	1	0.18	0.18	0.04
49	INT260819	Binding of OSM	2	0.12	0.66	0.03
50	INT266088	Positive_regulation of Localization of LIF	1	0.34	0.45	0.03
51	INT66346	Binding of LIF	7	0.47	0.9	0
52	INT322856	Regulation of Binding of OSM	1	0.10	0	0
53	INT297808	Regulation of Gene_expression of Nanos2	1	0.21	0.58	0
54	INT159329	Transcription of Lif	1	0.36	0.15	0
55	INT297800	Positive_regulation of Nanos2	1	0.41	1.22	0
56	INT300189	Negative_regulation of Localization of Lif	1	0.41	0.47	0
57	INT268657	Regulation of Localization of LIF	1	0.38	0.07	0
58	INT297794	Transcription of Nanos2	1	0.61	0.37	0
59	INT297818	Negative_regulation of Nanos2	1	0.38	0.99	0
60	INT297788	Gene_expression of Nanos2	1	0.59	4.02	0
61	INT216151	Transcription of OSM	1	0.19	0	0
62	INT297762	Positive_regulation of Gene_expression of Nanos2	1	0.41	1	0