GO:0045908

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Name negative regulation of vasodilation
Categary Process
Go Slim No
Go Link GO:0045908
Unique Molecular Interactions 292
Total Molecular Interactions 383
Total Single Events 6345
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of vasodilation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of vasodilation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
2 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
3 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
4 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
5 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16
6 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
7 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
8 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94
9 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
10 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
11 INT215646 Binding of Adora1 and P2rx2 1 0.13 0.51 0.85
12 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8
13 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
14 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79
15 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77
16 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
17 INT41165 Gtf3a Regulation of INS 1 0.00 0.15 0.74
18 INT41164 Binding of INS and SST 1 0.07 0.14 0.73
19 INT31643 POMC Regulation of INS 1 0.59 0.62 0.73
20 INT215647 Adora1 Positive_regulation of Kcnj5 1 0.00 0 0.62
21 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
22 INT29847 INS Regulation of Localization of AVP 1 0.23 0.24 0.59
23 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
24 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
25 INT103165 NGF Positive_regulation of Localization of INS 1 0.05 0 0.58
26 INT311256 Nt5e Positive_regulation of Positive_regulation of Adora1 1 0.49 0.19 0.54
27 INT29252 Regulation of INS Positive_regulation of GH1 1 0.26 0.08 0.54
28 INT29253 INS Positive_regulation of GH1 1 0.44 0.08 0.53
29 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
30 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49
31 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
32 INT101001 GHRH Regulation of Localization of INS 1 0.28 0 0.47
33 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43
34 INT215651 Binding of Adora1 and Cpa1 1 0.00 0 0.42
35 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4
36 INT285725 Binding of IGF1R and INS 1 0.27 0.07 0.4
37 INT29052 Binding of INS and INSRR 1 0.02 0.23 0.4
38 INT29053 Regulation of Binding of INS and INSRR 1 0.01 0.24 0.4
39 INT78621 PRL Positive_regulation of Localization of INS 2 0.06 0.5 0.39
40 INT291256 INS Negative_regulation of Positive_regulation of Mdk 1 0.01 1.65 0.39
41 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37
42 INT89386 INS Positive_regulation of Phosphorylation of AKT1 3 0.43 1.48 0.36
43 INT4382 RIPK2 Regulation of INS 1 0.12 0.58 0.36
44 INT183786 IL6 Negative_regulation of INS 1 0.09 1.61 0.35
45 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34
46 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34
47 INT183793 INS Negative_regulation of Binding of Ros1 1 0.16 1.66 0.34
48 INT183785 INS Positive_regulation of Gene_expression of NFKBIB 1 0.03 1.83 0.34
49 INT183780 INS Negative_regulation of Gene_expression of CYBB 1 0.02 1.74 0.34
50 INT4381 RIPK2 Positive_regulation of Localization of INS 1 0.13 0.53 0.34
51 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34
52 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33
53 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32
54 INT238895 Binding of CRP and INS 1 0.00 0.93 0.32
55 INT191240 SAE1 Regulation of Localization of INS 1 0.08 1.15 0.3
56 INT51275 IGF1 Negative_regulation of INS 2 0.35 0.98 0.29
57 INT215645 Binding of Adora1 and Kcnj5 1 0.00 0.08 0.29
58 INT291202 Positive_regulation of INS Positive_regulation of AKT1 1 0.01 0.76 0.29
59 INT71550 GTPBP4 Regulation of Localization of INS 1 0.00 0.16 0.28
60 INT291201 Regulation of INS Positive_regulation of GOPC 1 0.00 0.35 0.28
61 INT291200 INS Positive_regulation of GOPC 1 0.01 0.3 0.28
62 INT215653 Binding of Adora1 and Adora3 1 0.39 0.07 0.27
63 INT242878 INS Negative_regulation of Gene_expression of SPI1 1 0.04 1.81 0.27
64 INT224406 INS Regulation of Localization of PYY 1 0.11 0.27 0.27
65 INT224405 INS Regulation of Localization of CCK 1 0.12 0.27 0.27
66 INT74433 Binding of INS and Cpe 2 0.03 0 0.25
67 INT291261 INS Positive_regulation of Phosphorylation of Mdk 1 0.01 0.28 0.25
68 INT309888 INS Positive_regulation of Gene_expression of FAAH 1 0.04 1.19 0.25
69 INT215652 Binding of Adora1 and Npy1r 1 0.39 0.22 0.24
70 INT242875 INS Negative_regulation of Gene_expression of TLR4 1 0.11 1.41 0.24
71 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23
72 INT87750 IGFBP3 Negative_regulation of INS 1 0.11 0.86 0.23
73 INT63196 INS Positive_regulation of IL2 1 0.10 0.3 0.23
74 INT183247 ADA Negative_regulation of ADORA1 1 0.01 0 0.23
75 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
76 INT63195 INS Positive_regulation of CD8A 1 0.19 0.3 0.23
77 INT63199 INS Positive_regulation of PGR 1 0.11 0.3 0.23
78 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23
79 INT108808 Binding of IAPP and INS 1 0.32 1.36 0.23
80 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22
81 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22
82 INT214481 ROS1 Negative_regulation of Gene_expression of INS 1 0.00 0.37 0.22
83 INT39263 POMC Negative_regulation of INS 1 0.23 0.6 0.22
84 INT257397 Binding of FGD1 and INS 1 0.07 0.27 0.21
85 INT74437 Negative_regulation of Cpe Positive_regulation of Localization of INS 1 0.06 0 0.2
86 INT78622 POMC Positive_regulation of Localization of INS 1 0.07 0 0.2
87 INT3592 INS Positive_regulation of AVP 1 0.05 0.28 0.2
88 INT339901 Binding of INS and SCN5A 1 0.01 0.18 0.2
89 INT3591 Negative_regulation of INS Positive_regulation of AVP 1 0.04 0.28 0.2
90 INT74439 Negative_regulation of Cpe Positive_regulation of INS 1 0.06 0 0.2
91 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
92 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19
93 INT110717 CGA Positive_regulation of Localization of INS 1 0.03 0.5 0.19
94 INT32395 POMC Positive_regulation of INS 1 0.41 0.52 0.19
95 INT15523 INS Negative_regulation of FFAR1 1 0.02 0.35 0.16
96 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16
97 INT311227 INS Negative_regulation of HBA1 1 0.01 0.52 0.16
98 INT71548 ADRA2C Negative_regulation of Localization of INS 1 0.04 0.13 0.16
99 INT240620 Binding of INS and SHBG 4 0.12 3.35 0.15
100 INT207253 INS Negative_regulation of TXNIP 1 0.45 1.2 0.15
101 INT194136 Binding of HLA-E and INS 1 0.01 0.95 0.15
102 INT31641 POMC Regulation of Gene_expression of INS 1 0.26 0.25 0.15
103 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
104 INT249322 Positive_regulation of Adora1 Regulation of Rit2 1 0.10 0 0.14
105 INT141001 Negative_regulation of CPOX Regulation of Localization of INS 1 0.17 0.07 0.14
106 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
107 INT240909 Hmgcr Regulation of Gene_expression of Sod1 1 0.03 0.53 0.14
108 INT223084 Binding of Pdgfa and Pdgfb 2 0.17 0.83 0.13
109 INT321408 INS Positive_regulation of EGR1 1 0.03 2.36 0.13
110 INT117371 SUCLA2 Positive_regulation of Localization of INS 1 0.03 0 0.13
111 INT117372 SUCLA2 Regulation of Localization of INS 1 0.02 0 0.13
112 INT321414 INS Positive_regulation of Transcription of EGR1 1 0.03 2.36 0.13
113 INT255710 Binding of INS and LOC691138 1 0.00 0.51 0.12
114 INT352501 PRKAB1 Positive_regulation of INS 1 0.04 1.36 0.12
115 INT249321 Positive_regulation of Adora1 Regulation of Preb 1 0.20 0.09 0.12
116 INT263429 Pdgfb Positive_regulation of Localization of Abl1 1 0.01 0 0.12
117 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11
118 INT164923 INS Positive_regulation of GIP 1 0.43 0.18 0.11
119 INT267124 IGF1 Negative_regulation of Gene_expression of INS 2 0.14 0.18 0.1
120 INT26176 POMC Negative_regulation of Localization of INS 1 0.36 0.06 0.1
121 INT352500 Binding of FAT1 and INS 1 0.01 1.38 0.1
122 INT102248 INS Positive_regulation of Binding of HIF1A 1 0.13 0.96 0.1
123 INT346526 Binding of ADORA1 and PTH1R 1 0.01 0 0.1
124 INT350820 INS Regulation of SELS 1 0.13 1.11 0.1
125 INT27844 Binding of INS and Gh 1 0.03 0.1 0.1
126 INT262996 ADIPOQ Regulation of INS 1 0.13 1.25 0.1
127 INT102246 Binding of HIF1A and INS 1 0.07 0.96 0.1
128 INT27841 Binding of INS and GAL 1 0.04 0.1 0.1
129 INT267684 Binding of INS and ARID1B 3 0.10 6.08 0.09
130 INT164925 GIP Positive_regulation of Localization of INS 2 0.59 0.86 0.09
131 INT341235 Negative_regulation of INS Positive_regulation of Phosphorylation of Eif4ebp1 1 0.01 0.24 0.09
132 INT48194 Pdgfb Positive_regulation of Setd1a 1 0.23 0 0.09
133 INT114414 TF Regulation of INS 1 0.18 0.09 0.09
134 INT109959 INS Positive_regulation of FBF1 1 0.27 0.24 0.09
135 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08
136 INT173130 Binding of INS and PPARA 2 0.04 1.8 0.08
137 INT172836 Binding of INS and T2dm2 1 0.00 1.65 0.08
138 INT291040 Binding of CFH and INS 1 0.25 1.32 0.08
139 INT352517 Binding of INS and Adipoq 1 0.09 1.32 0.07
140 INT328306 GH1 Positive_regulation of Localization of INS 1 0.01 0.12 0.07
141 INT58648 Binding of HSD11B1 and INS 1 0.04 1.65 0.07
142 INT207824 KCNJ5 Regulation of Localization of INS 1 0.01 0 0.07
143 INT223085 Binding of Pdgfb and Insrr 1 0.01 0.91 0.07
144 INT58649 Binding of INS and Serpine1 1 0.01 1.64 0.07
145 INT207552 Binding of GH1 and INS 1 0.23 0.55 0.07
146 INT343477 Epo Positive_regulation of Pdgfb 1 0.11 0.31 0.06
147 INT311225 GLP1R Positive_regulation of Gene_expression of INS 1 0.49 0.33 0.06
148 INT202244 Igfbp1 Regulation of Localization of INS 1 0.06 0 0.06
149 INT329429 Binding of Col7a1 and Hmgcr 1 0.01 0.28 0.06
150 INT343471 Epo Positive_regulation of Gene_expression of Pdgfb 1 0.11 0.31 0.06
151 INT328305 GHS Positive_regulation of Localization of INS 1 0.02 0.07 0.05
152 INT218614 INS Positive_regulation of Binding of IGF1 1 0.39 0.79 0.05
153 INT298733 INS Regulation of ACSBG1 1 0.00 0.97 0.05
154 INT328387 INS Negative_regulation of Gene_expression of Ghrl 1 0.01 0.6 0.05
155 INT328371 Ghrl Negative_regulation of INS 1 0.03 0.13 0.05
156 INT258084 Binding of IL6 and Regulation of Gene_expression of INS 1 0.11 0.62 0.05
157 INT280057 Zglp1 Positive_regulation of Transcription of INS 1 0.04 0.52 0.05
158 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05
159 INT218616 Binding of IGFBP3 and INS 1 0.07 0.68 0.05
160 INT112644 INS Negative_regulation of OVGP1 1 0.43 0 0.05
161 INT89384 Negative_regulation of INS Positive_regulation of AKT1 2 0.36 1.37 0.04
162 INT213263 INS Positive_regulation of EDN1 1 0.12 0.54 0.04
163 INT207846 Hypism Regulation of INS 1 0.06 1.14 0.04
164 INT350015 ARID1B Regulation of Localization of INS 1 0.03 2.6 0.04
165 INT341231 INS Positive_regulation of Phosphorylation of Eif4ebp1 1 0.01 0.13 0.04
166 INT239320 Eef1a2 Negative_regulation of Hmgcr 1 0.06 0.89 0.04
167 INT314622 Binding of INS and Ex 1 0.08 0.44 0.04
168 INT263427 Pdgfb Positive_regulation of Phosphorylation of Rock1 1 0.00 0 0.04
169 INT223086 Binding of Pdgfb and Pdgfrb 1 0.33 0.46 0.04
170 INT267155 Binding of INS and SUGT1 1 0.02 0.81 0.04
171 INT350121 INS Negative_regulation of Positive_regulation of SHBG 1 0.09 1.48 0.04
172 INT199212 Binding of IGFBP1 and INS 1 0.05 1.77 0.04
173 INT350118 INS Negative_regulation of SHBG 1 0.09 1.42 0.04
174 INT311909 Gene_expression of Smad6 Negative_regulation of Gene_expression of Col10a1 1 0.02 0.54 0.04
175 INT89385 INS Positive_regulation of Phosphorylation of PTK2B 1 0.15 0.59 0.04
176 INT202231 Binding of IGF1 and INS 2 0.28 1.38 0.03
177 INT352519 INS Positive_regulation of Localization of Slc2a4 1 0.07 0.97 0.03
178 INT207554 GH1 Negative_regulation of Phosphorylation of INS 1 0.26 0.28 0.03
179 INT230854 INS Regulation of Positive_regulation of SNAP47 1 0.09 1.03 0.03
180 INT230851 INS Regulation of VCAM1 1 0.07 1.02 0.03
181 INT217648 Binding of fa and Hmgcr 1 0.00 0.89 0.03
182 INT230423 INS Negative_regulation of Lipg 1 0.03 0.74 0.03
183 INT328408 Nlrp1a Positive_regulation of Pdgfb 1 0.07 0.74 0.03
184 INT181618 NOS3 Positive_regulation of INS 1 0.02 0.59 0.03
185 INT285726 Binding of ALB and INS 1 0.22 0.61 0.03
186 INT242884 INS Regulation of SPI1 1 0.03 0.3 0.03
187 INT337728 ADAMTS2 Positive_regulation of Gene_expression of INS 1 0.02 0 0.03
188 INT228522 Tmem170b Positive_regulation of Localization of INS 1 0.01 0.66 0.03
189 INT207553 GH1 Negative_regulation of INS 1 0.27 0.28 0.03
190 INT235626 Binding of IARS and INS 1 0.08 0.15 0
191 INT246152 INS Regulation of S1PR2 1 0.02 0 0
192 INT246151 INS Negative_regulation of TXLNB 1 0.01 0 0
193 INT253085 NPPA Positive_regulation of INS 1 0.32 0 0
194 INT235623 Binding of INS and INSR 1 0.14 0.47 0
195 INT306947 NAMPT Regulation of INS 1 0.13 1.41 0
196 INT291106 INS Regulation of Gene_expression of PDK4 1 0.14 0 0
197 INT238871 Binding of INS and ARMC9 1 0.10 0.31 0
198 INT207260 INS Negative_regulation of Gene_expression of TXNIP 1 0.39 1.71 0
199 INT246148 INS Regulation of TXLNB 1 0.00 0 0
200 INT172759 INS Positive_regulation of Localization of REN 1 0.03 0.64 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of vasodilation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of vasodilation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT812 Localization of INS 1026 0.81 515.6 145.31
2 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
3 INT251 Regulation of INS 398 0.62 232.47 55.04
4 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
5 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
6 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
7 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
8 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
9 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
10 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01
11 INT14572 Binding of INS 205 0.48 175.43 13.38
12 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
13 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
14 INT19155 Binding of Adora1 25 0.47 6.41 10.72
15 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13
16 INT9350 Regulation of ADORA1 9 0.12 1.53 7.79
17 INT101699 Regulation of Adora1 14 0.61 3.7 7.59
18 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
19 INT182750 Gene_expression of Hmgcr 61 0.58 17.23 7.4
20 INT40159 Negative_regulation of Adora1 13 0.51 3.51 7.13
21 INT76197 Positive_regulation of ADORA1 7 0.59 5.06 7
22 INT9167 Binding of Adora1 6 0.40 0.53 6.9
23 INT76255 Gene_expression of ADORA1 11 0.78 2.51 6.85
24 INT70801 Gene_expression of Hmgcr 12 0.42 3.08 4.1
25 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9
26 INT65527 Positive_regulation of Positive_regulation of Adora1 4 0.46 0.67 3.71
27 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54
28 INT215604 Localization of Adora1 10 0.78 1.47 3.49
29 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
30 INT101477 Binding of ADORA1 8 0.31 0.42 3.07
31 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91
32 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9
33 INT54178 Regulation of Adora1 5 0.39 0.29 2.85
34 INT215608 Negative_regulation of Binding of Adora1 5 0.41 1.35 2.73
35 INT215601 Regulation of Positive_regulation of Adora1 9 0.60 1.74 2.66
36 INT215599 Positive_regulation of Positive_regulation of Adora1 7 0.47 2.29 2.58
37 INT114020 Gene_expression of Adora1 2 0.33 4.24 2.55
38 INT3315 Negative_regulation of Positive_regulation of INS 31 0.57 14.73 2.27
39 INT26177 Regulation of Regulation of INS 19 0.44 11.32 2.18
40 INT215611 Negative_regulation of Positive_regulation of Adora1 6 0.43 1.18 2.16
41 INT3866 Positive_regulation of Positive_regulation of INS 30 0.59 21.58 1.86
42 INT32558 Negative_regulation of ADORA1 5 0.12 2.77 1.86
43 INT124556 Negative_regulation of Positive_regulation of Adora1 3 0.51 1.2 1.81
44 INT168519 Positive_regulation of Gene_expression of Adora1 4 0.61 0.75 1.75
45 INT29763 Negative_regulation of Adora1 3 0.42 0 1.64
46 INT241721 Positive_regulation of Transcription of Adora1 3 0.50 1.39 1.41
47 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
48 INT113777 Binding of Hmgcr 3 0.09 2.29 1.35
49 INT241737 Transcription of Adora1 3 0.72 0.89 1.32
50 INT116903 Negative_regulation of Hmgcr 32 0.43 10.71 1.3
51 INT109104 Positive_regulation of Protein_catabolism of INS 4 0.50 4.44 1.24
52 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
53 INT3486 Positive_regulation of Regulation of INS 9 0.47 5.65 1.15
54 INT76254 Positive_regulation of Positive_regulation of ADORA1 2 0.43 1.27 1.14
55 INT183046 Transcription of INS 25 0.70 11.14 1.13
56 INT236163 Localization of Hmgcr 6 0.64 0.66 1.12
57 INT98975 Positive_regulation of Hmgcr 7 0.16 3.4 1.06
58 INT58470 Negative_regulation of Binding of INS 14 0.43 7.2 1.01
59 INT215606 Positive_regulation of Localization of Adora1 3 0.49 0.44 0.87
60 INT92880 Localization of ADORA1 2 0.80 0.09 0.84
61 INT12057 Regulation of Negative_regulation of INS 7 0.40 3.92 0.76
62 INT113512 Regulation of Gene_expression of ADORA1 1 0.11 0.19 0.73
63 INT54183 Regulation of Positive_regulation of Adora1 1 0.17 0 0.65
64 INT183789 Positive_regulation of Phosphorylation of INS 5 0.50 4.87 0.64
65 INT215607 Positive_regulation of Negative_regulation of Adora1 1 0.45 0 0.63
66 INT14570 Regulation of Positive_regulation of INS 8 0.45 4.97 0.62
67 INT14571 Regulation of Binding of INS 2 0.23 2.44 0.53
68 INT216748 Regulation of Localization of ADORA1 1 0.07 0.09 0.53
69 INT203688 Positive_regulation of Hmgcr 10 0.17 6.08 0.52
70 INT279525 Negative_regulation of Transcription of Adora1 1 0.43 0.26 0.51
71 INT249309 Regulation of Gene_expression of Adora1 6 0.39 0.51 0.49
72 INT215600 Regulation of Binding of Adora1 1 0.08 0.09 0.48
73 INT223081 Negative_regulation of Gene_expression of Pdgfb 2 0.37 3.07 0.47
74 INT213286 Positive_regulation of Binding of INS 6 0.50 4.85 0.45
75 INT213272 Negative_regulation of Phosphorylation of INS 7 0.40 9.13 0.44
76 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42
77 INT279524 Protein_catabolism of Adora1 1 0.88 0.34 0.38
78 INT279523 Positive_regulation of Protein_catabolism of Adora1 1 0.50 0.34 0.38
79 INT14569 Positive_regulation of Negative_regulation of INS 4 0.36 3.52 0.37
80 INT317875 Binding of Pdgfb 3 0.10 1.15 0.36
81 INT183066 Positive_regulation of Transcription of INS 8 0.49 5.31 0.34
82 INT232236 Negative_regulation of Gene_expression of Hmgcr 3 0.35 1.36 0.31
83 INT92881 Transcription of ADORA1 1 0.69 0 0.31
84 INT224100 Regulation of Negative_regulation of ADORA1 1 0.01 0.05 0.3
85 INT322907 Positive_regulation of Gene_expression of Hmgcr 4 0.03 1.45 0.28
86 INT224441 Negative_regulation of Pdgfb 2 0.33 1.61 0.27
87 INT207293 Negative_regulation of Negative_regulation of INS 12 0.49 6 0.26
88 INT250545 Regulation of Hmgcr 5 0.11 4.94 0.23
89 INT186700 Localization of Adora1 1 0.23 0 0.23
90 INT182749 Binding of Hmgcr 3 0.32 0.55 0.22
91 INT272889 Negative_regulation of Smad6 2 0.20 1.31 0.19
92 INT87196 Regulation of Hmgcr 3 0.45 0.7 0.14
93 INT249313 Negative_regulation of Gene_expression of Adora1 1 0.37 0 0.14
94 INT127623 Protein_catabolism of ADORA1 1 0.49 0.19 0.14
95 INT142342 Regulation of Negative_regulation of Hmgcr 1 0.20 0.48 0.1
96 INT228554 Negative_regulation of Negative_regulation of Hmgcr 1 0.24 0.44 0.08
97 INT228295 Negative_regulation of Transcription of INS 2 0.43 1.1 0.07
98 INT241720 Regulation of Transcription of Adora1 1 0.40 0.27 0.07
99 INT153688 Negative_regulation of Negative_regulation of Hmgcr 1 0.42 1.21 0.06
100 INT153690 Localization of Hmgcr 1 0.74 1.21 0.06
101 INT153689 Negative_regulation of Localization of Hmgcr 1 0.42 1.21 0.06
102 INT172971 Gene_expression of Smad6 2 0.37 1.77 0.04
103 INT311898 Positive_regulation of Gene_expression of Smad6 1 0.33 0.53 0.04
104 INT282271 Positive_regulation of Regulation of Hmgcr 1 0.12 1.44 0.04
105 INT295501 Negative_regulation of Gene_expression of Hmgcr 1 0.26 0.21 0.04
106 INT311758 Regulation of Gene_expression of Hmgcr 1 0.08 0 0.04
107 INT183060 Regulation of Transcription of INS 2 0.44 0.34 0
108 INT176185 Transcription of Hmgcr 2 0.31 0.56 0
109 INT223077 Regulation of Pdgfb 1 0.23 0.34 0
110 INT343453 Phosphorylation of Pdgfb 1 0.13 0.1 0
111 INT277696 Regulation of Positive_regulation of Pdgfb 1 0.03 0.52 0
112 INT247129 Positive_regulation of Protein_catabolism of Hmgcr 1 0.06 0.38 0
113 INT176209 Negative_regulation of Transcription of Hmgcr 1 0.25 0.3 0
114 INT173493 Regulation of Gene_expression of Hmgcr 1 0.33 0 0
115 INT247134 Protein_catabolism of Hmgcr 1 0.14 0.38 0
116 INT203686 Negative_regulation of Positive_regulation of Hmgcr 1 0.02 0.4 0
117 INT223079 Regulation of Gene_expression of Pdgfb 1 0.23 1.17 0
118 INT310173 Binding of Smad6 1 0.05 0 0
119 INT295506 Transcription of Hmgcr 1 0.43 0.19 0
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