GO:0047372

From wiki-pain
Revision as of 12:12, 29 January 2013 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Name acylglycerol lipase activity
Categary Function
Go Slim No
Go Link GO:0047372
Unique Molecular Interactions 76
Total Molecular Interactions 109
Total Single Events 1493
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for acylglycerol lipase activity. They are ordered first by their pain relevance and then by number of times they were reported for acylglycerol lipase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142437 Urb1 Negative_regulation of Faah 3 0.41 2.12 1.66
2 INT219686 Binding of CEL and COPD 1 0.12 11.35 1.26
3 INT310066 Negative_regulation of Pain1 Positive_regulation of Faah 1 0.03 1.32 1.23
4 INT310069 Negative_regulation of Pain1 Positive_regulation of Mgll 1 0.02 1.32 1.23
5 INT310068 Pain1 Positive_regulation of Faah 1 0.03 1.3 1.22
6 INT310067 Pain1 Positive_regulation of Mgll 1 0.02 1.29 1.21
7 INT76199 CASP1 Positive_regulation of CEL 1 0.06 0.32 1.14
8 INT285659 Binding of Faah and Mgll 1 0.15 0.99 1.11
9 INT141384 Urb1 Regulation of Faah 2 0.08 0.35 0.99
10 INT152490 Slc40a1 Negative_regulation of Faah 1 0.01 0.73 0.98
11 INT99578 Binding of CEL and Kit 1 0.04 1.07 0.81
12 INT278490 Negative_regulation of Faah Positive_regulation of Trpv1 1 0.38 0.6 0.76
13 INT160985 Urb1 Negative_regulation of Negative_regulation of Faah 1 0.41 1.36 0.74
14 INT95148 CEL Regulation of IL1B 1 0.24 0.88 0.7
15 INT26648 Binding of CEL and HP 1 0.04 0 0.58
16 INT156517 Binding of CNR1 and FAAH 3 0.38 1.53 0.53
17 INT328058 IL4 Positive_regulation of FAAH 1 0.29 4.29 0.53
18 INT160444 Tpsab1 Positive_regulation of Gene_expression of CEL 1 0.48 0.96 0.48
19 INT156521 Binding of CNR2 and FAAH 1 0.38 0.19 0.46
20 INT156518 Binding of FAAH and NAPEPLD 1 0.38 0.19 0.46
21 INT285661 Binding of Mgll and FAAH2 1 0.05 0.23 0.45
22 INT218783 Binding of Faah and Cfp 1 0.04 0.55 0.45
23 INT110744 Faah Positive_regulation of Positive_regulation of Aif1 1 0.10 0.36 0.4
24 INT219683 Binding of CEL and GOPC 1 0.04 3.11 0.38
25 INT137380 SLC46A2 Negative_regulation of Faah 1 0.00 0 0.32
26 INT17162 Binding of CEL and Lhb 1 0.06 0.38 0.3
27 INT328064 IL10 Positive_regulation of FAAH 1 0.05 1.48 0.26
28 INT309888 INS Positive_regulation of Gene_expression of FAAH 1 0.04 1.19 0.25
29 INT106993 CEL Positive_regulation of NR1I2 1 0.39 0.39 0.22
30 INT328059 IL4 Regulation of FAAH 1 0.25 4.57 0.21
31 INT59741 Faah Positive_regulation of Localization of Npy 1 0.01 0.16 0.21
32 INT59745 Faah Positive_regulation of Gene_expression of Npy 1 0.01 0.16 0.2
33 INT59743 Faah Positive_regulation of Transcription of Npy 1 0.01 0.16 0.2
34 INT49057 Positive_regulation of CEL Positive_regulation of Localization of LTC4S 1 0.41 0.28 0.18
35 INT147229 Positive_regulation of Ccdc80 Negative_regulation of Faah 1 0.02 0.06 0.16
36 INT147230 Ccdc80 Negative_regulation of Faah 1 0.02 0.06 0.16
37 INT231838 Pcdh8 Regulation of Cel 1 0.00 0.39 0.15
38 INT85816 Binding of CEL and TTR 1 0.39 0.77 0.14
39 INT231846 Pcdh8 Negative_regulation of Positive_regulation of Cel 1 0.00 0.91 0.14
40 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14
41 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13
42 INT92671 Binding of CEL and HLA-B 1 0.38 0.19 0.1
43 INT246535 Binding of Cel and Mag 1 0.01 7.26 0.1
44 INT32030 Binding of CEL and ERLEC1 1 0.08 0.42 0.1
45 INT152818 Faah Regulation of Trpc1 1 0.20 0.32 0.09
46 INT33808 IL36RN Regulation of Regulation of LIPE 1 0.13 0.09 0.09
47 INT33809 IL2 Regulation of Regulation of LIPE 1 0.23 0.09 0.09
48 INT152817 Faah Regulation of Trpv1 1 0.29 0.32 0.09
49 INT146842 Tnf Regulation of Lipe 1 0.19 0.4 0.08
50 INT33807 IL2 Negative_regulation of Negative_regulation of LIPE 1 0.16 0.06 0.07
51 INT231834 Trip12 Positive_regulation of Positive_regulation of Cel 1 0.00 0.75 0.05
52 INT133047 TNF Positive_regulation of Gene_expression of CEL 1 0.47 0.61 0.05
53 INT177350 Binding of CEL and PLA2G2A 1 0.06 0.08 0.04
54 INT328057 IL4 Regulation of Binding of FAAH 1 0.19 1.1 0.04
55 INT328065 IL4 Regulation of Gene_expression of FAAH 1 0.19 0.82 0.03
56 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
57 INT177352 Binding of CEL and PTN 1 0.01 0 0.03
58 INT328066 FAAH Regulation of IL4 1 0.16 0.97 0.03
59 INT319700 Ins1 Negative_regulation of Lipe 1 0.04 1.22 0.03
60 INT104540 FOXG1 Regulation of Lipc 1 0.02 0 0
61 INT323572 Negative_regulation of Lipe Positive_regulation of Positive_regulation of Ly6 1 0.00 0.1 0
62 INT239325 Eef1a2 Negative_regulation of Lipc 1 0.11 0.84 0
63 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0
64 INT304135 Binding of CEL and Positive_regulation of CASP8 1 0.00 0.52 0
65 INT44885 Binding of CEL and MET 1 0.39 0.15 0
66 INT326165 Binding of ABHD12 and Scrib 1 0.00 1.01 0
67 INT246536 Mag Regulation of Gene_expression of Cel 1 0.01 1.28 0
68 INT302586 Binding of Lipc and Apoa5 1 0.26 0.63 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for acylglycerol lipase activity. They are ordered first by their pain relevance and then by number of times they were reported in acylglycerol lipase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73340 Negative_regulation of Faah 134 0.59 38.67 85.03
2 INT95646 Negative_regulation of Faah 63 0.59 25.61 36.78
3 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58
4 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87
5 INT88365 Regulation of Faah 18 0.45 6.63 12.54
6 INT107524 Gene_expression of Faah 17 0.78 7.93 11.91
7 INT73338 Gene_expression of Faah 21 0.77 6.72 10.73
8 INT108405 Gene_expression of FAAH 48 0.78 28.22 9.97
9 INT133118 Negative_regulation of FAAH 25 0.59 13.05 9.37
10 INT73342 Protein_catabolism of Faah 19 0.97 5.11 8.99
11 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83
12 INT115733 Positive_regulation of Negative_regulation of Faah 8 0.50 3.62 7.26
13 INT169653 Negative_regulation of Mgll 6 0.42 3.75 6.16
14 INT110515 Regulation of Negative_regulation of Faah 5 0.43 2.84 5.2
15 INT23245 Positive_regulation of Gene_expression of CEL 19 0.69 14.81 4.92
16 INT18995 Binding of CEL 23 0.47 14.46 4.5
17 INT73341 Positive_regulation of Faah 12 0.65 4.94 4.28
18 INT73339 Localization of Faah 7 0.75 4.47 4.24
19 INT4464 Localization of CEL 21 0.80 8.09 3.88
20 INT102573 Protein_catabolism of Faah 8 0.80 2.89 3.52
21 INT175442 Gene_expression of Cel 22 0.34 21.36 3.33
22 INT104671 Binding of Faah 7 0.37 1.75 3.25
23 INT92151 Regulation of Faah 5 0.62 6.31 3.06
24 INT53813 Positive_regulation of Cel 20 0.58 19.39 3.05
25 INT153616 Gene_expression of Mgll 5 0.50 2.72 3.03
26 INT150870 Regulation of Gene_expression of Faah 3 0.45 2.65 2.87
27 INT107525 Positive_regulation of Faah 5 0.60 1.54 2.78
28 INT108403 Protein_catabolism of FAAH 9 0.89 2.5 2.75
29 INT150869 Positive_regulation of Gene_expression of Faah 4 0.70 3.78 2.2
30 INT153611 Protein_catabolism of Mgll 3 0.86 1 2.09
31 INT94673 Positive_regulation of FAAH 5 0.50 7.77 2.08
32 INT133621 Positive_regulation of Gene_expression of Faah 5 0.65 2.07 1.93
33 INT217691 Gene_expression of LIPE 24 0.70 29.84 1.87
34 INT47628 Regulation of CEL 9 0.60 4.5 1.85
35 INT168271 Regulation of Binding of Faah 1 0.45 0.91 1.81
36 INT115737 Regulation of Protein_catabolism of Faah 3 0.44 1 1.77
37 INT310063 Binding of Faah 1 0.32 1.36 1.76
38 INT143744 Regulation of FAAH 6 0.61 8.42 1.55
39 INT75694 Regulation of Gene_expression of CEL 9 0.60 6.08 1.53
40 INT143743 Positive_regulation of Gene_expression of FAAH 8 0.60 6.42 1.46
41 INT141272 Binding of FAAH 7 0.48 8.27 1.46
42 INT108402 Negative_regulation of Gene_expression of FAAH 6 0.43 5.99 1.39
43 INT133619 Negative_regulation of Gene_expression of Faah 4 0.47 1.21 1.32
44 INT11415 Negative_regulation of Cel 5 0.38 5.67 1.29
45 INT194489 Positive_regulation of LIPE 13 0.63 5.88 1.22
46 INT238854 Phosphorylation of LIPE 39 0.73 21.89 1.13
47 INT339387 Gene_expression of Lipe 1 0.20 2.39 1
48 INT158944 Regulation of Localization of Faah 1 0.39 0.85 0.96
49 INT322101 Localization of Cel 2 0.29 1.11 0.76
50 INT81622 Positive_regulation of Positive_regulation of CEL 4 0.49 3.94 0.73
51 INT169651 Positive_regulation of Protein_catabolism of Mgll 1 0.49 0.07 0.72
52 INT76127 Transcription of CEL 5 0.71 2.02 0.7
53 INT175450 Positive_regulation of Gene_expression of Cel 4 0.25 2.69 0.68
54 INT169654 Positive_regulation of Mgll 2 0.49 0.26 0.66
55 INT133620 Regulation of Gene_expression of Faah 1 0.37 0 0.65
56 INT108328 Negative_regulation of Gene_expression of CEL 6 0.57 2.56 0.63
57 INT183163 Positive_regulation of Positive_regulation of Cel 9 0.31 11.55 0.58
58 INT45724 Positive_regulation of Lipc 2 0.08 0.84 0.58
59 INT35135 Positive_regulation of Lipe 2 0.45 1.25 0.58
60 INT169489 Positive_regulation of Localization of CEL 1 0.45 0.34 0.58
61 INT33810 Regulation of LIPE 5 0.55 3.99 0.56
62 INT231823 Negative_regulation of Positive_regulation of Cel 2 0.17 2.34 0.56
63 INT147248 Positive_regulation of Positive_regulation of Faah 1 0.50 0.46 0.52
64 INT133576 Negative_regulation of Protein_catabolism of Faah 1 0.30 0.25 0.46
65 INT139690 Positive_regulation of Protein_catabolism of FAAH 1 0.50 0.52 0.44
66 INT53811 Regulation of Cel 4 0.23 2.1 0.43
67 INT161690 Localization of FAAH 2 0.61 0.38 0.43
68 INT228731 Negative_regulation of Gene_expression of Cel 2 0.17 1.12 0.41
69 INT108404 Negative_regulation of Protein_catabolism of FAAH 1 0.33 0.25 0.41
70 INT60601 Negative_regulation of Negative_regulation of CEL 1 0.41 0.34 0.4
71 INT131998 Positive_regulation of Protein_catabolism of Faah 1 0.40 0 0.36
72 INT135069 Regulation of Localization of CEL 1 0.44 0 0.34
73 INT238855 Negative_regulation of Gene_expression of LIPE 8 0.39 7 0.31
74 INT352167 Negative_regulation of Positive_regulation of CEL 1 0.04 1.07 0.31
75 INT59862 Phosphorylation of CEL 2 0.70 0.53 0.3
76 INT53814 Regulation of Positive_regulation of Cel 2 0.23 0.45 0.29
77 INT281746 Negative_regulation of Localization of CEL 1 0.03 0.6 0.29
78 INT310065 Positive_regulation of Localization of Faah 1 0.38 0.26 0.29
79 INT150868 Negative_regulation of Gene_expression of Faah 1 0.43 0.72 0.29
80 INT137377 Positive_regulation of Positive_regulation of Faah 1 0.34 0 0.28
81 INT339381 Positive_regulation of Gene_expression of Lipe 1 0.13 0.65 0.26
82 INT310064 Localization of Faah 1 0.56 0.21 0.26
83 INT238866 Positive_regulation of Gene_expression of LIPE 2 0.28 0.37 0.24
84 INT175459 Binding of Cel 2 0.11 6.62 0.24
85 INT110743 Negative_regulation of Binding of Faah 1 0.42 0.18 0.24
86 INT16158 Protein_catabolism of CEL 1 0.64 0 0.24
87 INT280226 Regulation of Protein_catabolism of FAAH 1 0.22 0.18 0.23
88 INT238865 Positive_regulation of Phosphorylation of LIPE 9 0.45 4.64 0.21
89 INT202425 Negative_regulation of Transcription of CEL 1 0.03 0.49 0.21
90 INT238869 Negative_regulation of Positive_regulation of LIPE 2 0.39 0.81 0.2
91 INT136107 Negative_regulation of Negative_regulation of Faah 1 0.39 0.38 0.19
92 INT292027 Localization of LIPE 1 0.72 1.73 0.18
93 INT161923 Positive_regulation of Binding of Faah 1 0.39 0.18 0.17
94 INT328073 Regulation of Binding of FAAH 1 0.42 1.01 0.16
95 INT280229 Regulation of Gene_expression of FAAH 3 0.57 2.06 0.15
96 INT95647 Negative_regulation of Negative_regulation of Faah 1 0.42 0.12 0.15
97 INT164729 Binding of Mgll 3 0.48 0.2 0.14
98 INT175454 Positive_regulation of Binding of Cel 1 0.15 0.92 0.14
99 INT292025 Transcription of LIPE 1 0.62 3.46 0.13
100 INT326145 Gene_expression of ABHD12 1 0.16 1.33 0.12
101 INT238862 Positive_regulation of Regulation of LIPE 1 0.30 0.12 0.12
102 INT93878 Positive_regulation of Lipc 4 0.47 3.09 0.11
103 INT292036 Binding of LIPE 1 0.34 1.96 0.1
104 INT261198 Phosphorylation of Lipe 1 0.07 0.92 0.1
105 INT33811 Negative_regulation of LIPE 4 0.39 3.97 0.09
106 INT328069 Regulation of Transcription of FAAH 1 0.25 2.28 0.07
107 INT103704 Transcription of Faah 1 0.71 0.07 0.07
108 INT328075 Transcription of FAAH 1 0.50 2.26 0.07
109 INT46943 Binding of Lipc 2 0.31 1.92 0.06
110 INT339380 Regulation of Gene_expression of Lipe 1 0.11 0.26 0.06
111 INT211537 Localization of Lipc 1 0.61 0.15 0.05
112 INT211555 Gene_expression of Lipc 1 0.52 0.16 0.05
113 INT328071 Positive_regulation of Binding of FAAH 1 0.47 1.09 0.04
114 INT292035 Regulation of Regulation of LIPE 1 0.48 0.51 0.04
115 INT292032 Positive_regulation of Localization of LIPE 1 0.45 0.63 0.04
116 INT292043 Regulation of Transcription of LIPE 1 0.24 1.03 0.04
117 INT238790 Regulation of Gene_expression of Cel 1 0.07 1.27 0
118 INT323511 Positive_regulation of Gene_expression of Mgll 1 0.15 0.52 0
119 INT144917 Negative_regulation of Positive_regulation of Faah 1 0.40 0 0
120 INT109291 Positive_regulation of Regulation of Faah 1 0.47 0.14 0
121 INT328072 Phosphorylation of FAAH 1 0.66 0.86 0
122 INT326143 Localization of ABHD12 1 0.18 0.95 0
123 INT323522 Regulation of Mgll 1 0.03 0.09 0
124 INT174763 Gene_expression of Lipc 1 0.56 0.72 0
125 INT323525 Regulation of Lipe 1 0.01 0.09 0
126 INT238860 Negative_regulation of Phosphorylation of LIPE 1 0.38 3.5 0
127 INT323518 Regulation of Gene_expression of Mgll 1 0.11 0.1 0
128 INT174765 Transcription of Lipc 1 0.57 0.61 0
129 INT238863 Regulation of Gene_expression of LIPE 1 0.29 2.61 0
130 INT238859 Regulation of Phosphorylation of LIPE 1 0.29 1.05 0
131 INT174764 Negative_regulation of Lipc 1 0.35 0.5 0
132 INT352610 Regulation of Regulation of CEL 1 0.00 0.55 0
133 INT97442 Positive_regulation of Binding of CEL 1 0.67 0 0
134 INT280225 Positive_regulation of Regulation of FAAH 1 0.38 0.64 0
135 INT323515 Positive_regulation of Positive_regulation of Mgll 1 0.11 0.1 0
136 INT323524 Negative_regulation of Binding of Mgll 1 0.09 0.2 0
137 INT323514 Negative_regulation of Lipe 1 0.02 0.1 0
138 INT323510 Negative_regulation of Gene_expression of Mgll 1 0.11 0.06 0
139 INT211559 Regulation of Lipc 1 0.20 0.22 0
140 INT323516 Localization of Mgll 1 0.19 0.19 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox