GO:0048146

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Name positive regulation of fibroblast proliferation
Categary Process
Go Slim No
Go Link GO:0048146
Unique Molecular Interactions 1829
Total Molecular Interactions 2643
Total Single Events 20755
Pain Genes Associated 79

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of fibroblast proliferation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of fibroblast proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
3 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
4 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
5 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
6 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
7 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
8 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
9 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
10 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
11 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
12 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
13 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
14 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
15 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
16 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
17 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
18 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
19 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
20 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
21 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
22 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
23 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
24 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
25 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
26 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
27 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
28 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
29 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
30 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
31 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
32 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
33 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
34 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
35 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
36 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
37 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
38 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
39 INT204558 Tens1 Negative_regulation of Pdgfc 1 0.01 0.25 1.2
40 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
41 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
42 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
43 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
44 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
45 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05
46 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
47 INT76001 Ngf Positive_regulation of Ngfr 1 0.16 0.93 1.05
48 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
49 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
50 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
51 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
52 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
53 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01
54 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
55 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
56 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
57 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
58 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
59 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
60 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
61 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
62 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
63 INT127672 Binding of NGFR and NTRK1 1 0.17 2.28 0.97
64 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
65 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
66 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
67 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
68 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
69 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
70 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
71 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
72 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
73 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
74 INT169469 Binding of Egfr and Tgfa 1 0.19 1.87 0.91
75 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
76 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91
77 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
78 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
79 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
80 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
81 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
82 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
83 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
84 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
85 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
86 INT116107 CDK4 Positive_regulation of Phosphorylation of EID1 1 0.01 0.32 0.86
87 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86
88 INT73538 Ngf Positive_regulation of Ngfr 2 0.41 1.05 0.85
89 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
90 INT69424 Binding of Agt and Oprd1 1 0.14 0 0.84
91 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
92 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
93 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
94 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
95 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8
96 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
97 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
98 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
99 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77
100 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
101 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76
102 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
103 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76
104 INT117412 RYBP Negative_regulation of LIG4 1 0.00 0.42 0.76
105 INT90123 Jun Positive_regulation of Gene_expression of Fos 1 0.47 0.39 0.76
106 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
107 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
108 INT190169 Regulation of JUN Positive_regulation of Localization of MMP12 1 0.30 0.07 0.74
109 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
110 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
111 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73
112 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
113 INT213726 Binding of Ngfr and Ntrk1 1 0.14 0.96 0.72
114 INT289333 Binding of Ngfr and Rtn4r 1 0.03 2.35 0.72
115 INT289332 Binding of Ngfr and Lingo1 1 0.04 2.36 0.72
116 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
117 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7
118 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
119 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
120 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
121 INT66581 Binding of JUN and Rare2 1 0.00 0.07 0.69
122 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 0.29 0.32 0.69
123 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
124 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
125 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
126 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
127 INT314560 RYBP Positive_regulation of Gene_expression of MYC 1 0.02 0.06 0.67
128 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
129 INT169213 Binding of EGFR and CARTPT 1 0.00 0.22 0.67
130 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
131 INT47145 Penk Negative_regulation of Agt 1 0.06 0 0.66
132 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
133 INT162878 Agt Regulation of Ang 1 0.21 1.15 0.66
134 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
135 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
136 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
137 INT57421 Oprd1 Regulation of Agt 1 0.29 0 0.62
138 INT128869 Gabrg1 Positive_regulation of Transcription of Jun 1 0.09 0.55 0.62
139 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
140 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
141 INT54487 Rabep2 Regulation of Gene_expression of Jun 1 0.06 0 0.61
142 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
143 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
144 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
145 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
146 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
147 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
148 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6
149 INT120206 Binding of UTS2R and Il1 1 0.17 1.28 0.59
150 INT120207 Binding of UTS2R and Il1f5 1 0.09 1.28 0.59
151 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
152 INT120348 Negative_regulation of Binding of DES and MYC 1 0.06 0.18 0.58
153 INT73654 Binding of Jun and Pim3 1 0.02 0.99 0.58
154 INT56116 Agt Positive_regulation of Lhb 1 0.15 0 0.58
155 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
156 INT120350 Binding of DES and MYC 1 0.05 0.17 0.58
157 INT2685 S100A6 Positive_regulation of Regulation of Thra 1 0.47 0.09 0.58
158 INT2684 S100A6 Regulation of Regulation of Thra 1 0.45 0.09 0.58
159 INT120347 Binding of KNG1 and MYC 1 0.21 0.17 0.58
160 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
161 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57
162 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
163 INT169286 CNR1 Positive_regulation of Phosphorylation of EGFR 1 0.45 0.18 0.57
164 INT90115 Ntrk2 Regulation of Jun 1 0.01 0.27 0.57
165 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
166 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
167 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
168 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
169 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
170 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
171 INT56117 Agt Positive_regulation of Positive_regulation of CGA 1 0.00 0 0.56
172 INT260845 Binding of Flt1 and Positive_regulation of Gene_expression of TNF 1 0.36 1.5 0.56
173 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
174 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
175 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
176 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
177 INT105422 Fosl2 Positive_regulation of Gene_expression of Penk 1 0.31 0 0.55
178 INT73367 Agt Negative_regulation of Localization of Calca 1 0.43 0.26 0.54
179 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
180 INT76002 Ngf Positive_regulation of Ngfr 1 0.05 0.48 0.53
181 INT245558 Runx3 Regulation of Ngfr 1 0.06 1 0.53
182 INT164262 TGM7 Negative_regulation of E2F1 1 0.16 1.08 0.53
183 INT271902 Binding of KCNK1 and Jun 1 0.12 0.08 0.53
184 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
185 INT256019 Agt Negative_regulation of Lnpep 1 0.23 1.76 0.53
186 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
187 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52
188 INT346205 Binding of CD74 and TPPP 1 0.02 0.87 0.51
189 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
190 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
191 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
192 INT127677 NGF Regulation of Gene_expression of NGFR 1 0.20 1.11 0.5
193 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
194 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
195 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49
196 INT161227 Binding of Ngfr and Tnf 1 0.06 0.41 0.49
197 INT108568 Calca Positive_regulation of Igf1 1 0.51 0.08 0.48
198 INT39078 Binding of Agt and Penk 1 0.24 0.42 0.48
199 INT47144 Negative_regulation of Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
200 INT47146 Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of fibroblast proliferation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of fibroblast proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
2 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
3 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
4 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
5 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
6 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
7 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
8 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
9 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
10 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
11 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
12 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
13 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
14 INT47764 Binding of Jun 106 0.48 22.62 31.39
15 INT1158 Regulation of Agt 106 0.61 29.4 30.29
16 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
17 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
18 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
19 INT116737 Localization of Mif 63 0.81 52.97 28.11
20 INT37296 Binding of Esr1 117 0.43 62.51 27.33
21 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
22 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
23 INT20462 Binding of ESR1 210 0.44 102.7 26.34
24 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
25 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
26 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
27 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
28 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
29 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
30 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8
31 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
32 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
33 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
34 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
35 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
36 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
37 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
38 INT2066 Localization of Agt 56 0.80 9.95 16.25
39 INT92354 Localization of ESR1 77 0.75 33.04 15.51
40 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
41 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
42 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
43 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
44 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
45 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
46 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36
47 INT17593 Regulation of Jun 37 0.60 5.5 14.35
48 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
49 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
50 INT2038 Localization of Esr1 104 0.79 40.12 13.27
51 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
52 INT3962 Regulation of AGT 50 0.62 20.96 13.01
53 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78
54 INT4199 Binding of Agt 76 0.48 21.06 12.66
55 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
56 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
57 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
58 INT66038 Positive_regulation of Ngfr 32 0.69 26.07 11.75
59 INT72949 Binding of Mif 31 0.46 23.12 11.65
60 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55
61 INT398 Localization of AGT 45 0.78 16.97 11.54
62 INT171253 Positive_regulation of BMI1 23 0.53 39.41 11.23
63 INT52233 Transcription of Jun 37 0.66 6.39 11.15
64 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
65 INT8065 Binding of AGT 54 0.48 20.54 10.85
66 INT60198 Binding of JUN 54 0.48 11.56 10.27
67 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
68 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
69 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
70 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
71 INT61264 Regulation of Jun 36 0.61 18.42 8.71
72 INT117553 Regulation of MIF 10 0.56 12.76 8.67
73 INT34777 Localization of IGF1 82 0.80 42.68 8.62
74 INT64815 Binding of Jun 49 0.48 21.47 8.59
75 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
76 INT75921 Negative_regulation of Ngfr 13 0.59 8.58 8.35
77 INT4021 Positive_regulation of PLA2G1B 35 0.70 23.27 8.2
78 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
79 INT48310 Binding of Ngfr 25 0.48 9.72 8.16
80 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
81 INT165228 Binding of BMI1 13 0.47 25.36 7.97
82 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
83 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
84 INT64816 Transcription of Jun 31 0.69 16.01 7.64
85 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
86 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59
87 INT4022 Negative_regulation of PLA2G1B 30 0.59 10.41 7.58
88 INT10344 Localization of Jun 23 0.73 6.36 7.46
89 INT61542 Positive_regulation of Ngfr 15 0.70 6.35 7.34
90 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33
91 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27
92 INT75497 Regulation of JUN 28 0.61 11.04 7.09
93 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
94 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9
95 INT47817 Positive_regulation of Positive_regulation of Jun 21 0.66 3.7 6.83
96 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
97 INT78713 Negative_regulation of Ngfr 9 0.54 7.07 6.73
98 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
99 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
100 INT517 Regulation of Mif 16 0.62 5.43 6.55
101 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38
102 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
103 INT11154 Binding of EGFR 149 0.48 96.23 6.29
104 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
105 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
106 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
107 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
108 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
109 INT121370 Positive_regulation of MIF 22 0.70 17.79 6.08
110 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
111 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
112 INT73649 Phosphorylation of Jun 28 0.80 11.01 5.87
113 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
114 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
115 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
116 INT151032 Localization of Igf1 49 0.76 26.32 5.71
117 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
118 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
119 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61
120 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
121 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31
122 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
123 INT93484 Negative_regulation of Positive_regulation of Jun 30 0.58 9.31 5.18
124 INT80038 Positive_regulation of Gene_expression of MYC 24 0.67 13.93 5.17
125 INT83442 Negative_regulation of MIF 18 0.57 9.51 5.12
126 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
127 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
128 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93
129 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
130 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
131 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78
132 INT121372 Positive_regulation of Gene_expression of MIF 17 0.60 14.78 4.73
133 INT124375 Gene_expression of Wnt2 67 0.56 38.03 4.67
134 INT96492 Gene_expression of NGFR 24 0.00 12.3 4.59
135 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
136 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
137 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
138 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
139 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
140 INT64711 Regulation of Ngfr 10 0.45 3.12 4.33
141 INT103914 Phosphorylation of Egfr 35 0.82 16.98 4.31
142 INT49360 Localization of Igf1 22 0.76 6.96 4.26
143 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
144 INT67936 Transcription of JUN 18 0.52 9.52 4.13
145 INT171252 Gene_expression of BMI1 21 0.70 26.98 4.11
146 INT100372 Gene_expression of Flt1 47 0.71 24.33 4.09
147 INT253970 Positive_regulation of Cd74 3 0.48 8.16 4.09
148 INT64163 Negative_regulation of Gene_expression of Jun 13 0.58 3.86 4.03
149 INT57157 Gene_expression of TDGF1 5 0.75 3.97 4.02
150 INT121170 Positive_regulation of Gene_expression of Ngfr 10 0.64 9.32 3.94
151 INT96776 Positive_regulation of Gene_expression of Pdgfa 8 0.40 7.79 3.93
152 INT6661 Positive_regulation of Positive_regulation of Jun 31 0.50 7.12 3.89
153 INT26368 Positive_regulation of S100A6 30 0.45 9.72 3.89
154 INT121171 Negative_regulation of Gene_expression of Ngfr 6 0.58 3.46 3.89
155 INT110180 Phosphorylation of JUN 23 0.80 11.21 3.83
156 INT64817 Positive_regulation of Binding of Jun 16 0.69 6.78 3.81
157 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
158 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
159 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
160 INT55907 Binding of Ngfr 13 0.47 5.79 3.75
161 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
162 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
163 INT15776 Localization of Jun 10 0.74 3.9 3.69
164 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
165 INT20461 Binding of Esr1 34 0.48 9.58 3.66
166 INT14837 Gene_expression of PLA2G1B 12 0.60 10.69 3.58
167 INT27466 Negative_regulation of Kng1 7 0.10 7.79 3.56
168 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
169 INT96777 Localization of Pdgfa 12 0.79 5.86 3.52
170 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
171 INT12385 Localization of NGFR 6 0.81 3.05 3.47
172 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45
173 INT61570 Positive_regulation of Transcription of Jun 10 0.35 1.62 3.45
174 INT187168 Binding of Cd74 13 0.27 11.2 3.44
175 INT61540 Negative_regulation of Gene_expression of Ngfr 11 0.59 6.36 3.43
176 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
177 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
178 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
179 INT20419 Negative_regulation of Gene_expression of MYC 19 0.57 9.7 3.29
180 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26
181 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
182 INT81453 Positive_regulation of Gene_expression of JUN 18 0.50 9.39 3.23
183 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23
184 INT70387 Negative_regulation of Positive_regulation of Jun 14 0.37 3.76 3.23
185 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
186 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
187 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
188 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11
189 INT117348 Regulation of EGFR 75 0.61 47.73 3.09
190 INT49659 Positive_regulation of Fosl2 11 0.43 1.71 3.08
191 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
192 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
193 INT68651 Negative_regulation of Positive_regulation of JUN 11 0.58 4.28 3.04
194 INT130226 Positive_regulation of Gene_expression of Mif 4 0.58 15.75 3.03
195 INT43948 Localization of PLA2G1B 17 0.78 6.92 2.99
196 INT16130 Binding of IGF1 67 0.48 27.43 2.95
197 INT73263 Negative_regulation of MYC 20 0.57 12.86 2.95
198 INT188047 Positive_regulation of Wnt2 51 0.58 31.41 2.94
199 INT36886 Transcription of Myc 6 0.69 3.16 2.86
200 INT167039 Gene_expression of Cd74 24 0.40 17.12 2.84
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