GO:0048154

Name S100 beta binding Categary Function Go Slim No Go Link GO:0048154

Unique Molecular Interactions 96 Total Molecular Interactions 146 Total Single Events 1331 Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for S100 beta binding. They are ordered first by their pain relevance and then by number of times they were reported for S100 beta binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT266391	Binding of Ager and S100a1	1	0.01	5.63	1.69
2	INT266406	Binding of APP and Ager	1	0.00	2.34	1.57
3	INT130839	Gfap Positive_regulation of S100B	1	0.51	1.9	1.56
4	INT274785	S100B Positive_regulation of Ngf	1	0.05	0.61	0.8
5	INT266408	Binding of HMGB1 and Ager	1	0.01	2.57	0.76
6	INT152867	HTR1A Negative_regulation of Localization of S100b	1	0.46	0	0.75
7	INT274786	Ngf Positive_regulation of Gene_expression of S100B	1	0.05	0.63	0.71
8	INT2685	S100A6 Positive_regulation of Regulation of Thra	1	0.47	0.09	0.58
9	INT2684	S100A6 Regulation of Regulation of Thra	1	0.45	0.09	0.58
10	INT290594	BDNF Positive_regulation of Localization of S100B	1	0.08	0.6	0.57
11	INT266381	Positive_regulation of Ager Positive_regulation of Nfkb1	1	0.00	0.77	0.55
12	INT266376	Binding of Ager and Itgam	1	0.00	2.31	0.54
13	INT266393	Binding of Ager and Fn1	1	0.00	0.82	0.39
14	INT266397	Binding of Ager and Col4a1	1	0.00	0.81	0.38
15	INT175016	Binding of REN and S100A6	2	0.11	1.13	0.37
16	INT266419	HMGB1 Positive_regulation of Ager	1	0.01	1.37	0.37
17	INT129769	Binding of LYZ and S100B	1	0.33	0.86	0.37
18	INT266402	Binding of S100P and Ager	1	0.00	2.25	0.35
19	INT266383	Binding of Ager and S100b	1	0.01	3.48	0.33
20	INT266375	S100b Positive_regulation of Ager	1	0.02	1.8	0.31
21	INT175017	Negative_regulation of Binding of REN and S100A6	1	0.13	0.45	0.29
22	INT175018	Positive_regulation of Binding of REN and S100A6	1	0.15	0.45	0.29
23	INT238802	Binding of Ager and Renbp	6	0.02	6.46	0.22
24	INT344833	Binding of Ager and Hmgb1	1	0.08	0.72	0.22
25	INT266405	S100b Positive_regulation of Gene_expression of TFAM	1	0.00	1.02	0.21
26	INT266417	Binding of TGM2 and S100a11	1	0.01	0.86	0.16
27	INT266422	HMGB1 Positive_regulation of Binding of Ager	1	0.01	0.92	0.16
28	INT122529	Apoe Regulation of S100B	1	0.18	0.29	0.16
29	INT266412	Binding of S100A12 and Ager	1	0.01	1.03	0.15
30	INT266377	Binding of S100a11 and Trp53	1	0.02	0.89	0.15
31	INT96590	Mog Regulation of S100B	1	0.32	0.97	0.13
32	INT261381	Nsdhl Regulation of Gene_expression of S100b	1	0.06	0.82	0.13
33	INT237442	Ass1 Positive_regulation of S100b	1	0.00	0.18	0.13
34	INT330800	Binding of S100A1 and S100B	1	0.32	0.5	0.13
35	INT266403	Negative_regulation of Binding of S100P and Ager	1	0.00	0.74	0.13
36	INT96589	Mbp Regulation of S100B	1	0.34	0.97	0.13
37	INT308659	Binding of Ager and ecs	1	0.01	1.14	0.12
38	INT308647	Ager Positive_regulation of Gene_expression of Bace1	1	0.09	1.01	0.12
39	INT308660	Binding of Ager and App	1	0.08	1.22	0.12
40	INT266384	Binding of Ager and S100a6	1	0.01	1.32	0.11
41	INT266386	Binding of S100a1 and Trp53	1	0.03	0.64	0.1
42	INT266385	S100a6 Positive_regulation of Ager	1	0.01	0.84	0.1
43	INT266373	Itgam Positive_regulation of Ager	1	0.01	0.84	0.1
44	INT266396	Binding of Ager and S100a4	1	0.01	0.59	0.1
45	INT326126	Binding of S100A1 and TP53	1	0.04	1.34	0.09
46	INT137395	Binding of CD99 and S100B	1	0.17	1.04	0.09
47	INT316112	Binding of S100B and SAE1	1	0.05	1.5	0.08
48	INT266389	Binding of C2 and S100a6	1	0.04	0.5	0.07
49	INT266390	Binding of S100a6 and Trp53	1	0.04	0.51	0.07
50	INT266398	Binding of S100b and Trp53	1	0.06	0.92	0.07
51	INT266388	S100a6 Negative_regulation of Mapk8	1	0.03	0.49	0.06
52	INT197617	Binding of S100a6 and Rb1	1	0.03	0	0.06
53	INT266374	Binding of S100a1 and S100a9	1	0.09	0.17	0.05
54	INT266387	Binding of S100a1 and S100a8	1	0.09	0.17	0.05
55	INT316109	TEAD1 Regulation of S100B	1	0.00	1.16	0.04
56	INT238803	Ager Positive_regulation of Cbl	1	0.01	1.57	0.04
57	INT266379	S100a8 Positive_regulation of Ager	1	0.01	0.3	0.04
58	INT266372	Binding of S100a1 and S100a4	1	0.11	0.15	0.04
59	INT266392	S100a9 Positive_regulation of Ager	1	0.01	0.3	0.04
60	INT204247	S100B Regulation of CD68	1	0.03	1.05	0.04
61	INT244656	Binding of S100B and SLC4A1	1	0.14	1.72	0.03
62	INT266415	Binding of ROS1 and S100a6	1	0.02	0.82	0.03
63	INT262617	Ager Positive_regulation of Rpe	1	0.00	0.81	0
64	INT180294	Positive_regulation of Binding of CPB1 and S100B	1	0.09	0	0
65	INT249185	Binding of S100B and Positive_regulation of CYBB	1	0.11	0	0
66	INT249195	Binding of CA2 and S100B	1	0.07	0	0
67	INT197907	Dlst Regulation of S100a6	1	0.10	0	0
68	INT266407	Binding of ALB and Ager	1	0.00	1.42	0
69	INT197902	Regulation of Oxt Regulation of S100a6	1	0.08	0	0
70	INT180295	Binding of CPB1 and S100B	1	0.08	0	0
71	INT180302	Positive_regulation of Binding of S100B and Tg(EGFR)0Jlj	1	0.05	0	0
72	INT249180	Binding of NCF2 and S100B	1	0.05	0	0
73	INT180303	Binding of S100B and Tg(EGFR)0Jlj	1	0.03	0	0
74	INT266395	Renbp Positive_regulation of Ager	1	0.00	0.31	0
75	INT197913	Oxt Regulation of Gene_expression of S100a6	1	0.08	0	0
76	INT235486	S100B Positive_regulation of Binding of CA2	1	0.13	0.08	0
77	INT197904	Dlst Positive_regulation of Positive_regulation of S100a6	1	0.09	0	0
78	INT197898	Dlst Regulation of Gene_expression of S100a6	1	0.14	0	0
79	INT249155	Binding of CYBA and S100B	1	0.06	0	0
80	INT249174	Binding of AKT1 and S100B	1	0.02	0	0
81	INT197905	Oxt Regulation of S100a6	1	0.08	0	0
82	INT249194	S100B Positive_regulation of CYBA	1	0.06	0	0

Single Events

The table below shows the top 100 pain related interactions that have been reported for S100 beta binding. They are ordered first by their pain relevance and then by number of times they were reported in S100 beta binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT17739	Gene_expression of S100B	226	0.78	132.7	26.4
2	INT64346	Positive_regulation of S100B	95	0.70	63.11	9.17
3	INT224366	Gene_expression of Ager	111	0.77	125.37	8.49
4	INT112986	Positive_regulation of S100b	19	0.70	17.61	6.86
5	INT117299	Localization of S100b	19	0.78	1.58	6.8
6	INT23465	Gene_expression of S100b	31	0.76	15.09	6.2
7	INT17742	Localization of S100B	44	0.80	17.14	4.65
8	INT26368	Positive_regulation of S100A6	30	0.45	9.72	3.89
9	INT224369	Binding of Ager	43	0.42	40.57	3.86
10	INT73602	Positive_regulation of Ager	35	0.69	30.66	3.74
11	INT82168	Positive_regulation of S100b	20	0.68	9.72	3.08
12	INT131929	Positive_regulation of Gene_expression of S100B	25	0.67	12.61	2.83
13	INT23775	Regulation of S100B	24	0.62	16.75	2.57
14	INT152865	Positive_regulation of Localization of S100b	3	0.68	0	2.53
15	INT195085	Gene_expression of S100b	12	0.56	12.26	2.33
16	INT26369	Gene_expression of S100A6	19	0.65	5.39	1.81
17	INT58563	Negative_regulation of S100B	13	0.51	11.75	1.77
18	INT152864	Regulation of Localization of S100b	2	0.52	0	1.66
19	INT155153	Binding of S100a1	15	0.35	6.42	1.63
20	INT143850	Gene_expression of S100a1	19	0.73	9.52	1.54
21	INT125767	Positive_regulation of Gene_expression of S100b	6	0.49	4.08	1.52
22	INT112988	Positive_regulation of Transcription of S100b	2	0.47	1.62	1.36
23	INT112987	Transcription of S100b	2	0.53	1.61	1.35
24	INT51064	Regulation of Gene_expression of S100B	13	0.60	5.02	1.34
25	INT125766	Regulation of S100b	7	0.38	4.31	1.33
26	INT161706	Negative_regulation of Gene_expression of S100B	8	0.43	2.69	1.06
27	INT293678	Positive_regulation of Gene_expression of S100A6	1	0.34	2.42	1.04
28	INT224368	Negative_regulation of Gene_expression of Ager	8	0.39	13.94	1.03
29	INT51066	Binding of S100B	24	0.48	13.5	0.97
30	INT43919	Negative_regulation of S100A6	19	0.16	4.45	0.96
31	INT169759	Localization of S100a1	5	0.43	0.78	0.9
32	INT224365	Positive_regulation of Gene_expression of Ager	13	0.69	11.6	0.88
33	INT180300	Positive_regulation of Positive_regulation of S100B	3	0.50	2.07	0.79
34	INT128447	Positive_regulation of Localization of S100B	2	0.67	0.9	0.79
35	INT224367	Negative_regulation of Ager	15	0.46	25.57	0.78
36	INT169766	Negative_regulation of S100a1	1	0.15	0	0.77
37	INT73433	Gene_expression of S100a6	10	0.71	2.74	0.76
38	INT36200	Gene_expression of S100A1	9	0.77	9.56	0.75
39	INT152863	Negative_regulation of Localization of S100b	1	0.42	0	0.75
40	INT147008	Negative_regulation of Gene_expression of S100b	2	0.27	0.55	0.74
41	INT195107	Localization of S100b	3	0.51	2.63	0.73
42	INT195095	Positive_regulation of Gene_expression of S100b	4	0.36	5.37	0.61
43	INT195094	Binding of S100b	2	0.35	3.49	0.51
44	INT143162	Gene_expression of S100a6	7	0.78	5.86	0.49
45	INT110498	Localization of S100a6	1	0.31	1.57	0.44
46	INT224372	Regulation of Gene_expression of Ager	6	0.39	4.98	0.43
47	INT125765	Negative_regulation of Positive_regulation of S100b	2	0.42	0.06	0.4
48	INT43387	Regulation of S100A6	2	0.15	0.4	0.4
49	INT266330	Positive_regulation of S100a1	4	0.44	2.98	0.39
50	INT213648	Phosphorylation of S100A6	2	0.30	1.43	0.36
51	INT143165	Positive_regulation of S100a6	8	0.69	3.5	0.34
52	INT156723	Regulation of Localization of S100B	2	0.44	2.61	0.34
53	INT266343	Positive_regulation of Positive_regulation of Ager	1	0.02	0.7	0.33
54	INT266327	Negative_regulation of Binding of S100a1	1	0.16	1.23	0.33
55	INT224370	Localization of Ager	7	0.65	11.64	0.3
56	INT197585	Positive_regulation of S100a6	3	0.43	1.67	0.29
57	INT266318	Negative_regulation of Negative_regulation of Ager	1	0.02	0.66	0.29
58	INT161705	Positive_regulation of Negative_regulation of S100B	1	0.50	0.56	0.28
59	INT224363	Regulation of Ager	3	0.36	4.62	0.26
60	INT143164	Positive_regulation of Gene_expression of S100a6	3	0.69	2.33	0.25
61	INT165392	Positive_regulation of Regulation of S100B	2	0.50	0.56	0.23
62	INT93077	Negative_regulation of Localization of S100B	3	0.57	0.58	0.2
63	INT73435	Negative_regulation of S100a6	1	0.21	0.26	0.2
64	INT143163	Regulation of S100a6	2	0.45	1.47	0.18
65	INT195111	Negative_regulation of Positive_regulation of S100b	1	0.06	1.06	0.18
66	INT51065	Transcription of S100B	3	0.60	0.83	0.17
67	INT293679	Positive_regulation of Positive_regulation of S100A6	2	0.24	1.19	0.14
68	INT347326	Regulation of S100a1	1	0.26	0.79	0.14
69	INT237441	Positive_regulation of Positive_regulation of S100b	2	0.36	3	0.12
70	INT266345	Binding of S100a11	1	0.13	0.76	0.12
71	INT266329	Localization of S100a11	1	0.26	0.82	0.11
72	INT266317	Phosphorylation of S100a11	1	0.24	0.81	0.11
73	INT147009	Regulation of Gene_expression of S100b	2	0.07	0.34	0.1
74	INT237438	Regulation of Gene_expression of S100b	2	0.31	2.45	0.1
75	INT266337	Protein_catabolism of Ager	1	0.02	0.26	0.1
76	INT197584	Binding of S100a6	2	0.14	0.81	0.09
77	INT152469	Binding of S100A1	2	0.36	1.55	0.08
78	INT82169	Negative_regulation of S100b	2	0.31	0.69	0.08
79	INT311813	Binding of S100A6	1	0.14	0.13	0.07
80	INT266338	Negative_regulation of Binding of Ager	1	0.02	1.37	0.05
81	INT266346	Gene_expression of S100a11	1	0.23	0.74	0.05
82	INT266336	Positive_regulation of Gene_expression of S100a11	1	0.18	0.74	0.05
83	INT180298	Regulation of Positive_regulation of S100B	3	0.39	1.09	0.04
84	INT238794	Positive_regulation of Localization of Ager	1	0.40	1.2	0.03
85	INT293673	Transcription of S100A6	1	0.38	0.15	0.03
86	INT222338	Positive_regulation of Gene_expression of S100a1	2	0.44	0.09	0
87	INT197866	Binding of S100a6	2	0.41	0	0
88	INT200568	Negative_regulation of Regulation of S100b	1	0.01	1.03	0
89	INT197879	Positive_regulation of Binding of S100a6	1	0.42	0	0
90	INT235488	Negative_regulation of Transcription of S100B	1	0.37	0.09	0
91	INT235487	Regulation of Transcription of S100B	1	0.39	0.09	0
92	INT77428	Negative_regulation of Positive_regulation of S100A6	1	0.15	0	0
93	INT266331	Transcription of S100a1	1	0.30	0.76	0
94	INT327450	Negative_regulation of Gene_expression of S100A6	1	0.12	0.19	0
95	INT163587	Positive_regulation of Positive_regulation of S100b	1	0.40	0	0
96	INT347327	Regulation of Gene_expression of S100a1	1	0.43	0.09	0
97	INT82588	Regulation of Gene_expression of S100A6	1	0.44	0.05	0
98	INT224371	Phosphorylation of Ager	1	0.70	0	0
99	INT238789	Regulation of Regulation of Ager	1	0.36	1.1	0
100	INT224364	Negative_regulation of Phosphorylation of Ager	1	0.37	0	0
101	INT315909	Positive_regulation of S100A1	1	0.49	0.71	0
102	INT197884	Transcription of S100a6	1	0.45	0	0
103	INT266323	Negative_regulation of S100a11	1	0.16	0.2	0
104	INT238786	Positive_regulation of Binding of Ager	1	0.40	6.84	0
105	INT293674	Positive_regulation of Transcription of S100A6	1	0.28	0.15	0