GO:0048168

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Name regulation of neuronal synaptic plasticity
Categary Process
Go Slim No
Go Link GO:0048168
Unique Molecular Interactions 463
Total Molecular Interactions 662
Total Single Events 6159
Pain Genes Associated 29

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of neuronal synaptic plasticity. They are ordered first by their pain relevance and then by number of times they were reported for regulation of neuronal synaptic plasticity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
2 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
3 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
4 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
5 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
6 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
7 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
8 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
9 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
10 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
11 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
12 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
13 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
14 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
15 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
16 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
17 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
18 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
19 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
20 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
21 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
22 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
23 INT130839 Gfap Positive_regulation of S100B 1 0.51 1.9 1.56
24 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
25 INT136843 Binding of Camk2a and Nrgn 1 0.47 0 1.47
26 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
27 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
28 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
29 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
30 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
31 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
32 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
33 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
34 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
35 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
36 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14
37 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
38 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
39 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
40 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
41 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
42 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
43 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
44 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
45 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
46 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
47 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
48 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
49 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 0.02 0.3 1.02
50 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
51 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
52 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
53 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
54 INT317544 Camk2a Regulation of Negative_regulation of Oprm1 1 0.20 0.07 1
55 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
56 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
57 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
58 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98
59 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
60 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
61 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
62 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
63 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
64 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
65 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
66 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
67 INT142129 Nrgn Regulation of Camk2a 1 0.48 0.25 0.89
68 INT223867 Camk2a Positive_regulation of Positive_regulation of Ltp 1 0.25 0 0.87
69 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87
70 INT120820 Binding of ASIC3 and Dlg4 3 0.02 0.11 0.84
71 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
72 INT150681 Pomc Positive_regulation of Camk2a 1 0.47 0.07 0.8
73 INT274785 S100B Positive_regulation of Ngf 1 0.05 0.61 0.8
74 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8
75 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
76 INT150679 Pomc Regulation of Gene_expression of Camk2a 1 0.30 0.07 0.79
77 INT147913 Phosphorylation of Camk2a Positive_regulation of Binding of Lpl 1 0.10 0 0.77
78 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
79 INT152947 Dlg4 Regulation of Sgk1 1 0.09 0.18 0.76
80 INT152945 Dlg4 Regulation of Cap1 1 0.11 0.18 0.76
81 INT116805 Phosphorylation of Camk2b Positive_regulation of Camk2a 1 0.07 0 0.76
82 INT178576 CNTN2 Positive_regulation of DPYD 1 0.05 2.18 0.76
83 INT178581 CNTN2 Positive_regulation of PTHLH 1 0.24 2.16 0.75
84 INT178577 CNTN2 Positive_regulation of IL2RA 1 0.03 2.16 0.75
85 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
86 INT152867 HTR1A Negative_regulation of Localization of S100b 1 0.46 0 0.75
87 INT152944 Dlg4 Regulation of Gpr88 1 0.12 0.18 0.75
88 INT329119 Binding of CNTN2 and CNTNAP2 1 0.08 2.41 0.73
89 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72
90 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
91 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
92 INT296290 Binding of Car1 and Grin1 1 0.11 0.32 0.72
93 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
94 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
95 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
96 INT274786 Ngf Positive_regulation of Gene_expression of S100B 1 0.05 0.63 0.71
97 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
98 INT71595 Camk2a Regulation of Negative_regulation of Oprm1 1 0.04 0 0.69
99 INT102344 Grin1 Regulation of Localization of C3orf52 1 0.00 0 0.68
100 INT114036 Binding of Grin1 and Psd 1 0.24 0.45 0.68
101 INT132696 Binding of Arc and Pag1 1 0.00 0.5 0.67
102 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
103 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
104 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66
105 INT168205 Binding of Dlg4 and Pik3cd 1 0.11 0.37 0.65
106 INT236003 Binding of HTR1A and Grin1 1 0.01 0.7 0.63
107 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
108 INT257717 Binding of Bdnf and Vgf 1 0.25 0.86 0.61
109 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
110 INT157141 Cpox Positive_regulation of Gene_expression of Camk2a 1 0.19 0.13 0.58
111 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
112 INT257715 Bdnf Positive_regulation of Transcription of Vgf 1 0.35 0.66 0.57
113 INT296472 Camk2a Positive_regulation of Prkaca 1 0.09 0.32 0.57
114 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
115 INT290594 BDNF Positive_regulation of Localization of S100B 1 0.08 0.6 0.57
116 INT257713 Ngf Positive_regulation of Transcription of Vgf 1 0.41 0.66 0.57
117 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
118 INT147273 Bdnf Regulation of Syp 1 0.24 0 0.56
119 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
120 INT251143 Binding of Grin2b and Dlg3 1 0.22 0.32 0.55
121 INT263776 Grin1 Positive_regulation of Ltp 2 0.17 0.17 0.54
122 INT69389 CNTN2 Positive_regulation of PENK 1 0.20 0.53 0.54
123 INT240808 Arc Regulation of Ins1 1 0.09 1.41 0.54
124 INT330553 Bcl2l11 Negative_regulation of Camk2a 1 0.01 0.38 0.52
125 INT274938 Ltp Positive_regulation of Localization of Ephb2 1 0.25 0 0.52
126 INT208121 Binding of Grin2a and Grin2b 3 0.35 0.06 0.51
127 INT76068 Gal Positive_regulation of Grin1 1 0.34 0 0.51
128 INT257720 Bdnf Regulation of Vgf 1 0.19 0.64 0.49
129 INT208119 Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
130 INT296457 Camk2a Positive_regulation of Phosphorylation of Gria1 1 0.19 0.28 0.49
131 INT250082 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Grin1 1 0.03 0.08 0.49
132 INT283736 Tbs1 Positive_regulation of Grin1 1 0.04 0 0.48
133 INT263746 Binding of Dlg4 and Neto1 1 0.27 0 0.48
134 INT257719 Ngf Regulation of Vgf 1 0.22 0.64 0.48
135 INT296471 Camk2a Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
136 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
137 INT117888 Gfap Regulation of Arc 1 0.05 0.37 0.46
138 INT117887 Glul Regulation of Arc 1 0.02 0.37 0.46
139 INT198931 Binding of Dlg4 and Lrp8 1 0.06 0.23 0.46
140 INT127392 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin1 1 0.08 0.71 0.45
141 INT127397 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin1 1 0.01 0.71 0.45
142 INT250083 Positive_regulation of Ltp Positive_regulation of Grin1 1 0.03 0 0.45
143 INT13247 Binding of Arc and Helt 1 0.00 0.37 0.45
144 INT317521 Camk2a Negative_regulation of Binding of Calm3 1 0.11 0 0.43
145 INT291963 Phex Negative_regulation of Gene_expression of Grin1 1 0.06 0.81 0.43
146 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
147 INT63372 Grin1 Regulation of Localization of Abat 1 0.20 0 0.43
148 INT296477 Binding of Cacng2 and Dlg4 1 0.04 0.22 0.42
149 INT135426 Binding of APBB1 and Dlg4 1 0.00 0.17 0.42
150 INT139654 Ntf3 Regulation of Gene_expression of Grin1 1 0.56 0.11 0.41
151 INT296296 Binding of Grin2b and Kcnip3 1 0.24 0 0.4
152 INT296300 Binding of Grin1 and Kcnip3 1 0.18 0 0.4
153 INT131180 Binding of Grin1 and Oprd1 1 0.24 0 0.39
154 INT138938 Agrp Regulation of Pmch 1 0.35 0.1 0.38
155 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
156 INT71596 Binding of Camk2a and Mpv17l 1 0.00 0 0.38
157 INT129769 Binding of LYZ and S100B 1 0.33 0.86 0.37
158 INT300608 Arc Regulation of Dnm2 1 0.15 0.27 0.37
159 INT274936 Ephb2 Regulation of Gene_expression of Fos 1 0.15 0 0.36
160 INT150196 Grm5 Regulation of Grin2b 1 0.45 0 0.36
161 INT274941 Ephb2 Regulation of Phosphorylation of Mapk1 1 0.19 0 0.36
162 INT120821 Dlg4 Positive_regulation of ASIC3 1 0.02 0 0.36
163 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36
164 INT274937 Ephb2 Regulation of Phosphorylation of Creb1 1 0.21 0 0.36
165 INT274933 Ephb2 Regulation of Phosphorylation of Camk2a 1 0.29 0 0.36
166 INT121757 Grin1 Regulation of Gene_expression of Fos 1 0.44 0.44 0.35
167 INT13374 Binding of Grin1 and Ltp 1 0.20 0 0.35
168 INT121758 Grin1 Regulation of Positive_regulation of Fos 1 0.44 0.44 0.35
169 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
170 INT272602 Binding of Dlg4 and Gria2 3 0.09 0.19 0.34
171 INT120817 Binding of Dlg4 and Lin7b 1 0.00 0 0.34
172 INT296465 Binding of Dlg4 and Rbm39 1 0.00 0.05 0.34
173 INT266383 Binding of Ager and S100b 1 0.01 3.48 0.33
174 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
175 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
176 INT283841 Dlg4 Negative_regulation of Insrr 1 0.01 0.95 0.33
177 INT317566 Car2 Positive_regulation of Camk2a 2 0.19 0.58 0.32
178 INT16382 Binding of Grin1 and Gnmt 1 0.04 0.17 0.32
179 INT198779 Binding of Dlg4 and Psd 10 0.25 0.09 0.31
180 INT231306 Prnp Regulation of Grin1 1 0.60 0.35 0.31
181 INT317545 Calm3 Positive_regulation of Camk2a 1 0.17 0 0.31
182 INT266375 S100b Positive_regulation of Ager 1 0.02 1.8 0.31
183 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
184 INT263749 Binding of Grin2b and Neto1 1 0.38 0 0.3
185 INT317571 Grin1 Regulation of Trpv1 1 0.00 0 0.29
186 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
187 INT317562 Binding of Grin1 and Gnptab 1 0.00 0 0.29
188 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
189 INT135425 Binding of Dlg4 and Dlg3 1 0.29 0.07 0.28
190 INT235874 Camk2a Positive_regulation of Slc6a4 1 0.11 0.14 0.28
191 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
192 INT240807 Arc Regulation of Gene_expression of Lepr 1 0.05 0.72 0.28
193 INT274944 Binding of Dlg4 and Pick1 1 0.04 0 0.28
194 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
195 INT334666 Slc9a1 Positive_regulation of Grin1 1 0.09 0.09 0.27
196 INT231035 Arc Regulation of Gene_expression of Fos 1 0.17 0.31 0.27
197 INT274940 Ephb2 Negative_regulation of Gene_expression of Fos 1 0.15 0.07 0.27
198 INT290957 Lsd Positive_regulation of Gene_expression of Egr2 1 0.11 0.1 0.26
199 INT310402 Binding of CALM1 and Grin1 1 0.00 0 0.26
200 INT274939 Binding of Dlg4 and Ephb6 1 0.12 0 0.25

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of neuronal synaptic plasticity. They are ordered first by their pain relevance and then by number of times they were reported in regulation of neuronal synaptic plasticity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
2 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
3 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
4 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
5 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
6 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
7 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7
8 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
9 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
10 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
11 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
12 INT115649 Gene_expression of Camk2a 95 0.78 33.22 38
13 INT11246 Binding of Grin1 65 0.48 14.53 36.93
14 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
15 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
16 INT114729 Phosphorylation of Camk2a 110 0.82 15.49 33.19
17 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
18 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
19 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
20 INT4459 Positive_regulation of Arc 74 0.69 33.61 28.29
21 INT73314 Gene_expression of Arc 133 0.78 67.78 27.44
22 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
23 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4
24 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
25 INT123386 Negative_regulation of Camk2a 48 0.58 12.57 23.78
26 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
27 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
28 INT16624 Localization of Grin1 38 0.79 8.46 17.15
29 INT62564 Gene_expression of Syp 40 0.76 15.56 17
30 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
31 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
32 INT115650 Positive_regulation of Gene_expression of Camk2a 37 0.70 17.68 15.73
33 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
34 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
35 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
36 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
37 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
38 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
39 INT112103 Binding of Grin1 28 0.48 4.21 12.08
40 INT86544 Positive_regulation of Camk2a 20 0.47 4.59 11.37
41 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
42 INT106477 Positive_regulation of Syp 21 0.68 8.69 10.3
43 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
44 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
45 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17
46 INT119527 Regulation of Camk2a 26 0.60 5.55 9.01
47 INT119529 Positive_regulation of Phosphorylation of Camk2a 16 0.60 1.49 8.94
48 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
49 INT71590 Gene_expression of Camk2a 17 0.78 2.3 8.63
50 INT108643 Gene_expression of Dlg4 61 0.76 8.63 8.58
51 INT119525 Negative_regulation of Positive_regulation of Camk2a 14 0.43 5.15 8.45
52 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
53 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
54 INT119940 Positive_regulation of Gene_expression of Arc 36 0.70 18.87 7.85
55 INT4457 Regulation of Arc 27 0.60 14.96 7.83
56 INT135113 Localization of Grin1 18 0.73 3.73 7.69
57 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
58 INT90715 Gene_expression of Egr2 12 0.73 1.64 7.17
59 INT150287 Positive_regulation of Ephb2 5 0.33 5.54 6.9
60 INT112986 Positive_regulation of S100b 19 0.70 17.61 6.86
61 INT117299 Localization of S100b 19 0.78 1.58 6.8
62 INT132468 Positive_regulation of Positive_regulation of Camk2a 20 0.70 2.76 6.7
63 INT50328 Positive_regulation of Vgf 8 0.70 13.98 6.37
64 INT115677 Positive_regulation of Gene_expression of Syp 15 0.63 4.69 6.25
65 INT23465 Gene_expression of S100b 31 0.76 15.09 6.2
66 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
67 INT121988 Negative_regulation of Gene_expression of Camk2a 8 0.59 4.76 5.72
68 INT80344 Regulation of Camk2a 9 0.56 0.99 5.66
69 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
70 INT135473 Negative_regulation of Gene_expression of Grin1 14 0.47 5.47 5.36
71 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
72 INT147898 Binding of Camk2a 16 0.37 4.01 4.87
73 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
74 INT49060 Negative_regulation of Camk2a 10 0.45 2.59 4.67
75 INT17742 Localization of S100B 44 0.80 17.14 4.65
76 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
77 INT151350 Regulation of Gene_expression of Camk2a 1 0.62 0.79 4.57
78 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
79 INT94277 Positive_regulation of Gene_expression of Egr2 7 0.49 0.69 4.4
80 INT93035 Negative_regulation of Transcription of Grin1 6 0.41 2.29 4.39
81 INT69395 Gene_expression of CNTN2 28 0.68 13.29 4.37
82 INT145532 Localization of Dlg4 25 0.79 1.97 4.36
83 INT71594 Positive_regulation of Gene_expression of Camk2a 8 0.47 1.07 4.35
84 INT111404 Regulation of Positive_regulation of Grin1 5 0.56 2.49 4.31
85 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
86 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
87 INT112100 Negative_regulation of Gene_expression of Grin2b 6 0.42 3.71 4.24
88 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
89 INT115354 Regulation of Binding of Grin1 2 0.43 1.15 4.08
90 INT120810 Binding of Dlg4 38 0.41 3.55 4.03
91 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
92 INT163500 Transcription of Grin2b 3 0.67 3.63 3.8
93 INT92516 Positive_regulation of Gene_expression of Grin1 8 0.45 2.53 3.77
94 INT106095 Localization of Arc 17 0.80 7.61 3.74
95 INT139646 Positive_regulation of Positive_regulation of Grin2b 4 0.42 3.89 3.74
96 INT84593 Positive_regulation of Binding of Grin1 6 0.48 2.74 3.72
97 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
98 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
99 INT257727 Transcription of Vgf 1 0.72 7.38 3.52
100 INT132888 Negative_regulation of Phosphorylation of Grin1 3 0.57 1.18 3.43
101 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
102 INT50326 Gene_expression of Vgf 11 0.78 4.41 3.2
103 INT82168 Positive_regulation of S100b 20 0.68 9.72 3.08
104 INT132887 Positive_regulation of Phosphorylation of Grin1 3 0.49 1.73 3.08
105 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
106 INT81734 Regulation of Gene_expression of Arc 12 0.43 7.77 3.06
107 INT123595 Regulation of Snca 7 0.62 4.3 3.06
108 INT71588 Phosphorylation of Camk2a 7 0.65 0.32 3.03
109 INT101779 Positive_regulation of Positive_regulation of Camk2a 5 0.31 1.57 3.02
110 INT137907 Phosphorylation of Ephb2 2 0.61 2.78 2.96
111 INT121759 Localization of Syp 8 0.73 1.78 2.84
112 INT131929 Positive_regulation of Gene_expression of S100B 25 0.67 12.61 2.83
113 INT150286 Gene_expression of Ephb2 3 0.39 2.57 2.74
114 INT50080 Binding of APOE 38 0.45 29.61 2.67
115 INT125998 Binding of Camk2a 3 0.36 0.89 2.67
116 INT5863 Positive_regulation of Egr2 7 0.40 1.44 2.64
117 INT101401 Positive_regulation of Transcription of Grin1 6 0.67 2.45 2.6
118 INT82284 Negative_regulation of Gene_expression of Arc 10 0.41 4.26 2.58
119 INT50325 Regulation of Vgf 2 0.62 4.4 2.58
120 INT23775 Regulation of S100B 24 0.62 16.75 2.57
121 INT152865 Positive_regulation of Localization of S100b 3 0.68 0 2.53
122 INT114026 Transcription of Grin1 7 0.67 3.13 2.45
123 INT218822 Negative_regulation of Phosphorylation of Camk2a 5 0.50 0.91 2.41
124 INT114024 Positive_regulation of Transcription of Grin1 1 0.49 1.69 2.37
125 INT195085 Gene_expression of S100b 12 0.56 12.26 2.33
126 INT106476 Regulation of Gene_expression of Syp 3 0.60 2.32 2.3
127 INT264600 Negative_regulation of Gene_expression of Syp 8 0.31 2.88 2.23
128 INT123588 Localization of Vgf 3 0.81 2.35 2.07
129 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
130 INT246518 Regulation of Negative_regulation of Grin2b 1 0.38 0.07 1.99
131 INT110242 Regulation of Syp 4 0.32 1.72 1.96
132 INT22021 Positive_regulation of Negative_regulation of Grin1 3 0.49 0.69 1.89
133 INT127125 Localization of Snca 6 0.81 8.24 1.88
134 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87
135 INT198748 Regulation of Gene_expression of Dlg4 10 0.44 2.16 1.85
136 INT111405 Negative_regulation of Regulation of Grin1 1 0.54 0.09 1.81
137 INT323912 Regulation of ARC 1 0.01 1.06 1.78
138 INT58563 Negative_regulation of S100B 13 0.51 11.75 1.77
139 INT154515 Localization of Ephb2 2 0.73 0.17 1.77
140 INT100135 Negative_regulation of Syp 6 0.57 2.76 1.74
141 INT138660 Positive_regulation of Regulation of Grin1 2 0.24 1.59 1.71
142 INT152864 Regulation of Localization of S100b 2 0.52 0 1.66
143 INT86539 Positive_regulation of Phosphorylation of Camk2a 3 0.55 0.18 1.65
144 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
145 INT119526 Regulation of Gene_expression of Camk2a 4 0.45 1.39 1.58
146 INT135112 Regulation of Phosphorylation of Grin1 2 0.44 0.3 1.58
147 INT4458 Positive_regulation of Positive_regulation of Arc 5 0.49 2.19 1.55
148 INT125767 Positive_regulation of Gene_expression of S100b 6 0.49 4.08 1.52
149 INT72329 Transcription of Arc 20 0.67 12.52 1.51
150 INT74592 Regulation of Transcription of Grin1 2 0.60 1.05 1.51
151 INT152939 Regulation of Dlg4 9 0.60 1.09 1.49
152 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
153 INT115355 Regulation of Negative_regulation of Grin1 2 0.23 0.23 1.44
154 INT162811 Localization of Camk2a 4 0.71 0.61 1.42
155 INT59040 Regulation of Positive_regulation of Grin1 3 0.27 1.61 1.42
156 INT296265 Regulation of Phosphorylation of Grin2b 2 0.44 1.06 1.4
157 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
158 INT112988 Positive_regulation of Transcription of S100b 2 0.47 1.62 1.36
159 INT112987 Transcription of S100b 2 0.53 1.61 1.35
160 INT51064 Regulation of Gene_expression of S100B 13 0.60 5.02 1.34
161 INT251602 Regulation of Binding of Grin1 2 0.25 0.05 1.34
162 INT125766 Regulation of S100b 7 0.38 4.31 1.33
163 INT92976 Localization of Camk2a 1 0.61 0.21 1.23
164 INT96330 Regulation of Regulation of Grin1 2 0.14 0.83 1.2
165 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16
166 INT105326 Regulation of Localization of Grin1 3 0.44 0.76 1.16
167 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
168 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
169 INT151753 Transcription of Snca 6 0.69 1.99 1.11
170 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11
171 INT143091 Positive_regulation of Negative_regulation of Grin2b 2 0.44 0.9 1.09
172 INT291961 Negative_regulation of Regulation of Grin2b 1 0.30 1.65 1.09
173 INT136284 Binding of Syp 3 0.36 0.73 1.08
174 INT317484 Positive_regulation of Localization of Grin1 1 0.28 0.11 1.07
175 INT161706 Negative_regulation of Gene_expression of S100B 8 0.43 2.69 1.06
176 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05
177 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
178 INT198750 Positive_regulation of Gene_expression of Dlg4 5 0.68 0.6 1.02
179 INT93296 Gene_expression of Pmch 6 0.64 0.48 1
180 INT135114 Negative_regulation of Localization of Grin1 1 0.41 0.17 1
181 INT116646 Regulation of Negative_regulation of Gsk3b 2 0.44 0.39 0.99
182 INT51066 Binding of S100B 24 0.48 13.5 0.97
183 INT3131 Binding of Arc 5 0.34 2.68 0.94
184 INT151752 Positive_regulation of Transcription of Snca 2 0.50 0.99 0.92
185 INT124246 Binding of Snca 10 0.37 6.53 0.9
186 INT261360 Binding of Gsk3b 5 0.36 2.85 0.9
187 INT80348 Regulation of Regulation of Camk2a 1 0.24 0.06 0.9
188 INT123589 Positive_regulation of Positive_regulation of Vgf 7 0.50 2.92 0.88
189 INT107970 Positive_regulation of Protein_catabolism of CNTN2 1 0.20 1.22 0.88
190 INT287686 Positive_regulation of Positive_regulation of Syp 2 0.36 1.08 0.86
191 INT125993 Negative_regulation of Binding of Camk2a 1 0.08 0.07 0.85
192 INT143092 Negative_regulation of Negative_regulation of Grin2b 1 0.27 0.33 0.83
193 INT167285 Positive_regulation of Phosphorylation of Gsk3b 17 0.50 5.92 0.82
194 INT156945 Positive_regulation of Negative_regulation of Gsk3b 6 0.38 4.58 0.82
195 INT66365 Positive_regulation of Gene_expression of Gsk3b 2 0.07 0.95 0.81
196 INT151349 Transcription of Camk2a 1 0.72 0.09 0.8
197 INT180300 Positive_regulation of Positive_regulation of S100B 3 0.50 2.07 0.79
198 INT128447 Positive_regulation of Localization of S100B 2 0.67 0.9 0.79
199 INT116644 Phosphorylation of Gsk3b 4 0.61 0.68 0.78
200 INT204002 Negative_regulation of Gene_expression of Gsk3b 15 0.55 8.57 0.77
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