GO:0048839

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Name inner ear development
Categary Process
Go Slim No
Go Link GO:0048839
Unique Molecular Interactions 858
Total Molecular Interactions 1200
Total Single Events 9216
Pain Genes Associated 50

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for inner ear development. They are ordered first by their pain relevance and then by number of times they were reported for inner ear development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
2 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
3 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
4 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
5 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
6 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
7 INT354207 Igfbp7 Positive_regulation of Accn3 1 0.52 6.55 3.24
8 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95
9 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
10 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
11 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
12 INT340117 Binding of Bdnf and Pain1 1 0.01 2.48 2.55
13 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
14 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
15 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
16 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
17 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
18 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
19 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
20 INT151889 Binding of Adarb1 and DLL1 1 0.00 0 1.66
21 INT354210 Binding of Igfbp7 and Accn3 1 0.27 3.91 1.64
22 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
23 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
24 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
25 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
26 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
27 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
28 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
29 INT326194 Bdnf Regulation of Slc12a5 1 0.05 0.85 1.35
30 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
31 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
32 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
33 INT96708 Bdnf Positive_regulation of Localization of SST 1 0.01 0 1.3
34 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
35 INT159655 Binding of BDNF and INSRR 2 0.00 1.25 1.26
36 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
37 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24
38 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23
39 INT311914 Il1 Negative_regulation of Gene_expression of Col2a1 1 0.01 1.94 1.23
40 INT105918 Binding of FUT1 and SLC9A3R2 1 0.00 0.14 1.2
41 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
42 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
43 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
44 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
45 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
46 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
47 INT349590 Aap Positive_regulation of Cytl1 1 0.13 1.31 1.15
48 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
49 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
50 INT87320 Ngf Regulation of Gene_expression of Bdnf 2 0.38 0.97 1.06
51 INT150787 ZNF398 Positive_regulation of Gene_expression of SPARC 1 0.13 1.02 1.05
52 INT134534 Binding of Bdnf and Psds1 1 0.01 0 1.05
53 INT204551 Binding of Col2a1 and Positive_regulation of Cia1 1 0.03 1.74 1.03
54 INT160541 Binding of BDNF and PSIP1 4 0.49 1.94 1.02
55 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02
56 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
57 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01
58 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
59 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
60 INT105668 Binding of AAVS1 and BDNF 1 0.08 0.94 0.95
61 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95
62 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
63 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93
64 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
65 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
66 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
67 INT180772 Bdnf Regulation of Trpv1 1 0.11 0.29 0.9
68 INT180777 Bdnf Regulation of Gene_expression of Trpv1 1 0.18 0.29 0.9
69 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
70 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
71 INT152700 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
72 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
73 INT152701 Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
74 INT326663 Bdnf Regulation of Positive_regulation of Arc 1 0.16 1.46 0.88
75 INT152694 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
76 INT48463 Bdnf Positive_regulation of Gene_expression of Sst 1 0.25 0 0.88
77 INT152695 Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
78 INT261783 Bdnf Regulation of Gene_expression of Slc12a5 1 0.09 0 0.87
79 INT337899 Positive_regulation of MC3R Positive_regulation of Gene_expression of Bdnf 1 0.31 0 0.87
80 INT215596 Bdnf Positive_regulation of Negative_regulation of Slc12a5 1 0.14 0.76 0.86
81 INT326664 Bdnf Positive_regulation of Arc 1 0.27 1.07 0.86
82 INT326661 Bdnf Positive_regulation of Gene_expression of Arc 1 0.27 1.96 0.86
83 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
84 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
85 INT261786 Bdnf Negative_regulation of Slc12a5 1 0.14 0.05 0.85
86 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84
87 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83
88 INT340113 Comt Regulation of Bdnf 1 0.21 0.74 0.82
89 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
90 INT128042 Bdnf Positive_regulation of Phosphorylation of Ephb1 1 0.22 0.2 0.8
91 INT56499 Neurod1 Positive_regulation of Maoa 1 0.47 0 0.8
92 INT180782 Bdnf Positive_regulation of Calca 1 0.16 0.77 0.8
93 INT151882 Binding of YY1 and DLL1 1 0.00 0 0.79
94 INT128041 Bdnf Positive_regulation of Trib3 1 0.10 0.29 0.79
95 INT151883 Negative_regulation of Binding of YY1 and DLL1 1 0.00 0 0.79
96 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
97 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
98 INT224281 Bdnf Regulation of Gene_expression of Gap43 1 0.36 0.4 0.77
99 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
100 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76
101 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
102 INT111194 Binding of NEUROD1 and Pck1 1 0.39 0 0.75
103 INT98770 Binding of Dll1 and Gt(pU21)50Imeg 1 0.05 0 0.74
104 INT75399 Regulation of Binding of Dll1 and Oprd1 1 0.08 0 0.74
105 INT98771 Binding of Dll1 and Oprm1 1 0.29 0 0.74
106 INT75398 Binding of Dll1 and Oprd1 1 0.11 0 0.74
107 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
108 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
109 INT180765 Calca Regulation of Binding of Bdnf 1 0.15 0.15 0.72
110 INT219035 Nkx1-1 Regulation of Gene_expression of Bdnf 1 0.13 0.88 0.7
111 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69
112 INT287099 Binding of Bdnf and T 1 0.10 1.1 0.69
113 INT250932 IL1B Regulation of Gene_expression of BDNF 1 0.06 0.24 0.69
114 INT224892 Bdnf Regulation of Localization of Ltp 1 0.03 0.17 0.69
115 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69
116 INT224893 Bdnf Regulation of Ltp 1 0.03 0.17 0.69
117 INT161186 Bdnf Regulation of Gene_expression of Ntrk2 1 0.44 1.05 0.68
118 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
119 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
120 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
121 INT180805 Bdnf Regulation of Sorbs1 1 0.01 0.14 0.67
122 INT161183 NMS Positive_regulation of Gene_expression of Bdnf 1 0.40 1.3 0.67
123 INT82306 Bdnf Positive_regulation of Gene_expression of Fos 1 0.68 0.64 0.65
124 INT242635 Binding of Bdnf and Ntrk3 3 0.25 0.98 0.64
125 INT148381 UFM1 Positive_regulation of JAG1 1 0.00 1.13 0.63
126 INT148379 UFM1 Positive_regulation of DLL1 1 0.00 1.13 0.63
127 INT154263 NEUROD1 Positive_regulation of Gene_expression of GAL 1 0.50 0.06 0.63
128 INT326193 Bdnf Positive_regulation of Car2 2 0.14 0.11 0.62
129 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
130 INT219277 Mapkapk2 Positive_regulation of Pla2g1b 1 0.03 0.46 0.61
131 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
132 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
133 INT219278 Mapkapk2 Positive_regulation of Pla2g2a 1 0.05 0.46 0.61
134 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61
135 INT257717 Binding of Bdnf and Vgf 1 0.25 0.86 0.61
136 INT271194 Binding of Bdnf and Gopc 1 0.03 0.49 0.6
137 INT287096 Binding of Bdnf and FL 1 0.16 1.15 0.6
138 INT164455 Ngf Negative_regulation of Bdnf 1 0.05 0.59 0.59
139 INT86644 Binding of OPRD1 and DLL1 1 0.28 0.17 0.58
140 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
141 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
142 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
143 INT257715 Bdnf Positive_regulation of Transcription of Vgf 1 0.35 0.66 0.57
144 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
145 INT290594 BDNF Positive_regulation of Localization of S100B 1 0.08 0.6 0.57
146 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
147 INT145718 Positive_regulation of Plat Positive_regulation of Bdnf 1 0.20 0 0.56
148 INT147273 Bdnf Regulation of Syp 1 0.24 0 0.56
149 INT261481 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.02 0.21 0.56
150 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
151 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
152 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
153 INT147274 Bdnf Regulation of Gap43 1 0.37 0 0.55
154 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
155 INT150800 THBS3 Negative_regulation of SPARC 1 0.23 0.51 0.53
156 INT143854 Ngf Regulation of Transcription of Bdnf 1 0.09 0.61 0.53
157 INT119745 NEUROD1 Regulation of Gene_expression of BHLHE22 1 0.11 0.26 0.53
158 INT240192 RBX1 Negative_regulation of BDNF 1 0.08 0.13 0.52
159 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
160 INT143862 Bdnf Positive_regulation of Gene_expression of NUP214 1 0.27 0.61 0.52
161 INT143859 Bdnf Positive_regulation of Gene_expression of Nfatc1 1 0.00 0.61 0.52
162 INT95042 Binding of NEUROD1 and Olr1246 1 0.02 0.23 0.51
163 INT163481 Binding of Bdnf and Positive_regulation of Regulation of Helt 1 0.21 0 0.51
164 INT163480 Bdnf Positive_regulation of Regulation of Helt 1 0.22 0 0.51
165 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
166 INT250933 IL1B Positive_regulation of Gene_expression of BDNF 1 0.10 0.27 0.5
167 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5
168 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5
169 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
170 INT242638 Binding of BDNF and Gdnf 1 0.29 0 0.49
171 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
172 INT114543 Bdnf Positive_regulation of Prkcg 1 0.21 0 0.49
173 INT257720 Bdnf Regulation of Vgf 1 0.19 0.64 0.49
174 INT219038 Creb1 Regulation of Gene_expression of Bdnf 1 0.25 0.25 0.49
175 INT304578 Negative_regulation of HDAC9 Positive_regulation of Gene_expression of Bdnf 1 0.06 0.9 0.49
176 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
177 INT320451 ECT Positive_regulation of Gene_expression of BDNF 1 0.05 1.21 0.49
178 INT165582 Binding of Bdnf and Gdnf 1 0.36 0.47 0.49
179 INT108568 Calca Positive_regulation of Igf1 1 0.51 0.08 0.48
180 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48
181 INT273110 Bdnf Regulation of Positive_regulation of Gria1 1 0.43 0 0.47
182 INT305735 Binding of Bdnf and Creb1 1 0.08 0.49 0.47
183 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47
184 INT309127 Edc4 Positive_regulation of Bdnf 1 0.04 0.37 0.47
185 INT305746 Positive_regulation of Creb1 Positive_regulation of BDNF 1 0.32 0.41 0.47
186 INT305743 Binding of Bdnf and Positive_regulation of Positive_regulation of Creb1 1 0.11 0.49 0.47
187 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47
188 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
189 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
190 INT233668 Cebpd Negative_regulation of Cebpg 1 0.43 0.66 0.46
191 INT305736 Positive_regulation of Creb1 Positive_regulation of Bdnf 1 0.10 0.41 0.46
192 INT96710 Ntf3 Regulation of BDNF 1 0.02 0 0.45
193 INT224282 Binding of Bdnf and Il6 1 0.08 0.26 0.45
194 INT169478 TGFB3 Positive_regulation of Tgfa 1 0.01 0.9 0.44
195 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 0.12 0.54 0.44
196 INT305745 Binding of Bdnf and Positive_regulation of BDNF 1 0.17 0.44 0.44
197 INT261782 Bdnf Positive_regulation of Gene_expression of Slc12a5 1 0.18 0 0.44
198 INT180781 Bdnf Positive_regulation of Zbtb38 1 0.00 0.93 0.44
199 INT354218 Igfbp7 Positive_regulation of Accn1 1 0.04 0.74 0.44
200 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43

Single Events

The table below shows the top 100 pain related interactions that have been reported for inner ear development. They are ordered first by their pain relevance and then by number of times they were reported in inner ear development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1
2 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82
3 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68
4 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01
5 INT67682 Localization of Bdnf 204 0.81 72.36 88.92
6 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12
7 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5
8 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
9 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24
10 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81
11 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55
12 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64
13 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
14 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
15 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77
16 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78
17 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5
18 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99
19 INT47685 Positive_regulation of Positive_regulation of Bdnf 32 0.70 20.05 27.03
20 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83
21 INT96557 Binding of Bdnf 46 0.47 21.74 24.26
22 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
23 INT113925 Localization of Bdnf 59 0.79 24.03 22.76
24 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
25 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
26 INT102203 Transcription of Bdnf 35 0.71 18.26 20.59
27 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36
28 INT106556 Negative_regulation of Gene_expression of Bdnf 42 0.59 34.71 17.64
29 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
30 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42
31 INT96299 Positive_regulation of Localization of Bdnf 35 0.70 15.67 16.09
32 INT163479 Binding of Bdnf 36 0.48 25.77 14.83
33 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
34 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
35 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7
36 INT100655 Regulation of BDNF 51 0.60 21.49 13.14
37 INT47692 Negative_regulation of Positive_regulation of Bdnf 18 0.59 9.64 13.14
38 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
39 INT56883 Positive_regulation of Dll1 8 0.49 3.49 12.25
40 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
41 INT56048 Positive_regulation of Transcription of Bdnf 24 0.70 8.33 11.83
42 INT37618 Gene_expression of Col2a1 50 0.70 33.88 11.58
43 INT72579 Localization of BDNF 56 0.80 14.84 10.65
44 INT238920 Positive_regulation of SLC9A3R2 44 0.50 27.86 10.51
45 INT103474 Regulation of Gene_expression of BDNF 40 0.60 12.14 9.65
46 INT54834 Gene_expression of Col2a1 48 0.72 13.5 9.41
47 INT136012 Regulation of Transcription of Bdnf 6 0.45 2.76 9.2
48 INT56884 Gene_expression of Dll1 9 0.48 1.15 8.98
49 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89
50 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84
51 INT56019 Gene_expression of Dll1 11 0.78 3.38 8.71
52 INT75998 Transcription of BDNF 61 0.69 11.03 8.27
53 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
54 INT55859 Binding of Dll1 6 0.35 0 7.64
55 INT102207 Positive_regulation of Transcription of Bdnf 13 0.69 5.49 7.18
56 INT64370 Gene_expression of Neurod1 22 0.75 5.19 7.1
57 INT58607 Negative_regulation of Dll1 9 0.43 1.89 7.06
58 INT132860 Binding of BDNF 33 0.47 14.7 6.99
59 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
60 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
61 INT70287 Positive_regulation of Gene_expression of Dll1 6 0.70 3.58 6.55
62 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
63 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
64 INT103477 Negative_regulation of Gene_expression of BDNF 23 0.52 10.63 6.26
65 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24
66 INT91065 Regulation of Transcription of Bdnf 13 0.62 12.48 6.13
67 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
68 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
69 INT6098 Binding of NEUROD1 17 0.47 3.4 5.99
70 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
71 INT151032 Localization of Igf1 49 0.76 26.32 5.71
72 INT56047 Negative_regulation of Transcription of Bdnf 16 0.59 8.02 5.67
73 INT354202 Gene_expression of Igfbp7 1 0.45 8.29 5.58
74 INT110666 Phosphorylation of Bdnf 12 0.69 5.67 5.21
75 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
76 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
77 INT67681 Negative_regulation of Localization of Bdnf 12 0.50 4.37 5.07
78 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
79 INT69396 Gene_expression of H2-K1 72 0.65 38.16 4.56
80 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
81 INT71406 Regulation of Dll1 3 0.35 0.79 4.44
82 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
83 INT49360 Localization of Igf1 22 0.76 6.96 4.26
84 INT113926 Positive_regulation of Localization of Bdnf 7 0.56 3.15 4.25
85 INT10542 Gene_expression of DLL1 16 0.71 3.7 4.21
86 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
87 INT106553 Positive_regulation of Positive_regulation of Bdnf 11 0.43 5.35 4.07
88 INT40036 Binding of DLL1 10 0.36 2.88 3.95
89 INT124815 Binding of Col2a1 9 0.37 10.27 3.93
90 INT72179 Negative_regulation of Dll1 5 0.33 4.09 3.84
91 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
92 INT152743 Positive_regulation of Localization of BDNF 7 0.56 4.04 3.74
93 INT82305 Regulation of Localization of Bdnf 10 0.40 3 3.62
94 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
95 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
96 INT20011 Regulation of NEUROD1 10 0.44 3.83 3.53
97 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
98 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5
99 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
100 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
101 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
102 INT49190 Regulation of Dll1 3 0.44 0.26 3.24
103 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23
104 INT48462 Positive_regulation of Negative_regulation of Bdnf 8 0.70 1 3.2
105 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
106 INT39867 Binding of Col2a1 9 0.35 7.65 3.18
107 INT54832 Negative_regulation of Gene_expression of Col2a1 6 0.50 2.53 3.16
108 INT183212 Positive_regulation of Regulation of Bdnf 4 0.45 1.57 3.14
109 INT126567 Positive_regulation of Positive_regulation of BDNF 8 0.59 6.16 3.06
110 INT171884 Positive_regulation of Gene_expression of Col2a1 11 0.23 8.04 3.02
111 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
112 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
113 INT55148 Binding of Dll1 5 0.48 0.66 2.97
114 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
115 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
116 INT280461 Negative_regulation of Localization of Bdnf 3 0.37 2.63 2.9
117 INT39856 Binding of Neurod1 8 0.47 1.44 2.88
118 INT354201 Positive_regulation of Igfbp7 1 0.40 5.32 2.87
119 INT354205 Positive_regulation of Gene_expression of Igfbp7 1 0.40 4.02 2.87
120 INT90094 Gene_expression of Cytl1 14 0.75 12.75 2.81
121 INT66891 Negative_regulation of Positive_regulation of Dll1 1 0.41 0 2.72
122 INT119516 Positive_regulation of Phosphorylation of Bdnf 3 0.21 2.81 2.68
123 INT201646 Negative_regulation of Transcription of Bdnf 8 0.58 7.14 2.59
124 INT67329 Positive_regulation of Positive_regulation of Dll1 2 0.32 0 2.56
125 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
126 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5
127 INT139735 Positive_regulation of Transcription of Igf1 4 0.53 1.93 2.49
128 INT354204 Binding of Igfbp7 1 0.32 4.44 2.49
129 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
130 INT132315 Positive_regulation of DLL1 6 0.67 3.4 2.45
131 INT66544 Binding of Igf1 23 0.46 8.33 2.44
132 INT11476 Positive_regulation of H2-K1 17 0.26 9.48 2.23
133 INT111038 Gene_expression of Cdkn1b 23 0.75 25.35 2.22
134 INT168945 Positive_regulation of Binding of Bdnf 4 0.50 1.7 2.14
135 INT82048 Positive_regulation of Neurod1 7 0.49 2.39 2.13
136 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
137 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
138 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96
139 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
140 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95
141 INT142341 Positive_regulation of Transcription of Igf1 8 0.49 2.44 1.95
142 INT102205 Negative_regulation of Positive_regulation of Bdnf 6 0.50 3.77 1.91
143 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9
144 INT303352 Gene_expression of Jag1 19 0.73 7.68 1.89
145 INT13999 Positive_regulation of Positive_regulation of NEUROD1 5 0.67 4.07 1.86
146 INT96703 Negative_regulation of Localization of BDNF 4 0.41 0.42 1.86
147 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
148 INT92622 Regulation of Positive_regulation of Bdnf 4 0.39 2.16 1.81
149 INT85337 Negative_regulation of Slc9a3r2 5 0.34 2.32 1.8
150 INT164407 Negative_regulation of Gene_expression of Col2a1 6 0.39 4 1.78
151 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
152 INT159099 Negative_regulation of Positive_regulation of Dll1 1 0.25 0.74 1.76
153 INT105920 Binding of SLC9A3R2 5 0.36 1.99 1.75
154 INT159100 Regulation of Positive_regulation of Dll1 1 0.26 0.7 1.73
155 INT44637 Positive_regulation of Slc9a3r2 18 0.55 7.27 1.72
156 INT102204 Positive_regulation of Regulation of Bdnf 3 0.43 1.74 1.67
157 INT240201 Regulation of Transcription of BDNF 5 0.45 1.09 1.66
158 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
159 INT159098 Negative_regulation of Gene_expression of Dll1 1 0.18 0.62 1.65
160 INT220992 Protein_catabolism of Col2a1 8 0.40 5.55 1.64
161 INT204277 Positive_regulation of Cytl1 3 0.67 2.56 1.64
162 INT103471 Positive_regulation of Transcription of BDNF 4 0.44 4.25 1.63
163 INT52757 Localization of Dll1 1 0.20 0 1.6
164 INT97318 Gene_expression of SPARC 11 0.67 5.07 1.59
165 INT65602 Negative_regulation of Neurod1 7 0.42 2.52 1.55
166 INT137505 Positive_regulation of Cdkn1b 18 0.67 10.55 1.54
167 INT164410 Negative_regulation of Col2a1 4 0.39 3.75 1.53
168 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52
169 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
170 INT118311 Binding of Slc9a3r2 5 0.45 2.03 1.49
171 INT49361 Regulation of Positive_regulation of Igf1 2 0.45 2.15 1.49
172 INT140245 Binding of Gli3 3 0.36 2.65 1.46
173 INT207005 Regulation of Localization of Bdnf 6 0.45 3.85 1.45
174 INT64371 Positive_regulation of Gene_expression of Neurod1 4 0.64 1.56 1.45
175 INT32184 Negative_regulation of Col2a1 9 0.42 3.05 1.43
176 INT105296 Regulation of DLL1 3 0.11 0.77 1.43
177 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41
178 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
179 INT27356 Localization of NEUROD1 8 0.78 3.44 1.39
180 INT155699 Phosphorylation of Bdnf 5 0.81 1.49 1.37
181 INT90491 Binding of Igf1 25 0.44 9.75 1.36
182 INT240207 Regulation of Positive_regulation of BDNF 1 0.45 0.32 1.36
183 INT112314 Regulation of Binding of Bdnf 3 0.38 0.61 1.34
184 INT54831 Regulation of Gene_expression of Col2a1 4 0.39 2.3 1.31
185 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
186 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29
187 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
188 INT160009 Transcription of CDKN1B 2 0.67 1.43 1.29
189 INT143759 Gene_expression of SOX2 46 0.55 11.12 1.24
190 INT128714 Transcription of Col2a1 6 0.52 2.13 1.24
191 INT18971 Positive_regulation of Gene_expression of NEUROD1 8 0.67 1.91 1.23
192 INT114220 Negative_regulation of Gene_expression of Cdkn1b 4 0.33 4.11 1.23
193 INT303362 Regulation of Jag1 2 0.22 2.91 1.22
194 INT133371 Negative_regulation of Binding of Dll1 1 0.41 0.5 1.22
195 INT176463 Protein_catabolism of Col2a1 4 0.35 1.94 1.2
196 INT169251 Gene_expression of Phox2b 9 0.70 3.88 1.17
197 INT142616 Negative_regulation of Positive_regulation of Igf1 5 0.43 1.56 1.16
198 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
199 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12
200 INT97369 Regulation of Gene_expression of NEUROD1 1 0.26 0.25 1.12
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