GO:0050702

From wiki-pain
Revision as of 06:55, 29 January 2013 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Name interleukin-1 beta secretion
Categary Process
Go Slim No
Go Link GO:0050702
Unique Molecular Interactions 112
Total Molecular Interactions 165
Total Single Events 1050
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interleukin-1 beta secretion. They are ordered first by their pain relevance and then by number of times they were reported for interleukin-1 beta secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
2 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
3 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14
4 INT107858 PRSS1 Positive_regulation of F2RL1 6 0.12 4.23 1.29
5 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21
6 INT156238 Binding of F2rl1 and Tnfsf14 1 0.08 2.85 1.08
7 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
8 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9
9 INT126268 Tpsab1 Positive_regulation of F2rl1 2 0.35 1.65 0.88
10 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
11 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84
12 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
13 INT156239 Tnfsf14 Positive_regulation of F2rl1 1 0.09 2.4 0.81
14 INT124292 Binding of Trpv1 and F2rl1 1 0.46 1.1 0.81
15 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
16 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77
17 INT224463 TPSAB1 Positive_regulation of F2RL1 2 0.03 1.49 0.76
18 INT341534 INSRR Positive_regulation of F2RL1 1 0.00 1.4 0.7
19 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
20 INT252857 Binding of F2rl1 and Trpa1 1 0.22 0.84 0.63
21 INT138332 Binding of P2rx3 and F2rl1 1 0.35 0.25 0.59
22 INT112312 tryptase Positive_regulation of F2rl1 2 0.08 0.23 0.57
23 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
24 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
25 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
26 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
27 INT100726 TNF Positive_regulation of Gene_expression of F2RL1 2 0.27 1.9 0.46
28 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
29 INT312813 Binding of F2rl1 and Tpsab1 1 0.01 0.26 0.46
30 INT156234 Tnfsf14 Positive_regulation of Transcription of F2rl1 1 0.09 1.26 0.42
31 INT156233 Positive_regulation of Tnfsf14 Positive_regulation of F2rl1 1 0.09 1.15 0.4
32 INT150333 4930519F16Rik Positive_regulation of F2rl1 1 0.00 0.67 0.38
33 INT224461 F2RL1 Positive_regulation of CALCRL 1 0.00 0.37 0.31
34 INT224462 Positive_regulation of F2RL1 Positive_regulation of MMP1 1 0.10 0.47 0.28
35 INT292570 Binding of F2RL1 and HTR1A 1 0.07 0.8 0.28
36 INT292568 Binding of F2RL1 and MRGPRX1 1 0.07 0.81 0.28
37 INT292571 Positive_regulation of F2RL1 Positive_regulation of Localization of IL6 1 0.07 0.8 0.27
38 INT292563 F2RL1 Negative_regulation of TNF 1 0.15 0.73 0.25
39 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
40 INT341538 F2 Positive_regulation of F2RL1 1 0.02 0.68 0.24
41 INT292556 Binding of F2RL1 and TLR4 1 0.05 0.52 0.22
42 INT292557 Binding of F2RL1 and MYD88 1 0.08 0.52 0.22
43 INT207151 PLA2G6 Positive_regulation of Localization of F2rl1 1 0.16 0.73 0.18
44 INT341531 F2RL1 Regulation of CD55 1 0.33 0.41 0.18
45 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
46 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
47 INT207147 Pla2g1b Positive_regulation of Localization of F2rl1 1 0.03 0.73 0.18
48 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
49 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
50 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
51 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
52 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
53 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
54 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
55 INT105253 Positive_regulation of Binding of Rnpep and F2rl1 1 0.02 0 0.15
56 INT105252 Binding of Rnpep and F2rl1 1 0.01 0 0.15
57 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
58 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
59 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
60 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
61 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
62 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
63 INT341529 PRSS1 Positive_regulation of Gene_expression of F2RL1 1 0.06 0 0.11
64 INT341543 PRSS1 Positive_regulation of Transcription of F2RL1 1 0.06 0 0.11
65 INT42224 ABCA1 Positive_regulation of CYBB 1 0.01 0 0.09
66 INT42225 Binding of ABCA1 and DECR1 1 0.02 0 0.08
67 INT292569 F2RL1 Positive_regulation of Negative_regulation of MAPK8 1 0.22 0 0.08
68 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07
69 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
70 INT293233 IDO1 Positive_regulation of ABCA1 1 0.01 0 0.06
71 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05
72 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05
73 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05
74 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05
75 INT341535 F2RL1 Positive_regulation of Gene_expression of THBS1 1 0.28 0.75 0.04
76 INT175631 F2RL1 Positive_regulation of Positive_regulation of MMP1 1 0.08 0.69 0.04
77 INT105260 4930519F16Rik Positive_regulation of F2rl1 1 0.00 0 0.03
78 INT175628 F2R Positive_regulation of F2RL1 1 0.04 1.46 0.03
79 INT230136 OSBPL8 Regulation of Binding of ABCA1 1 0.07 0.17 0.03
80 INT341537 F2RL1 Positive_regulation of TSC1 1 0.01 0.76 0.03
81 INT207343 Negative_regulation of CPOX Negative_regulation of Gene_expression of ABCA1 1 0.09 0 0.03
82 INT284392 Binding of ABCA1 and Vegfa 1 0.00 0.71 0
83 INT229927 CD59 Negative_regulation of Binding of ABCA1 1 0.01 0 0
84 INT229923 Binding of ABCA1 and C9 1 0.00 0.74 0
85 INT308542 Binding of AIM1 and AIM2 1 0.12 0 0
86 INT284372 Binding of ABCA1 and AMT 1 0.00 0 0
87 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0
88 INT297056 Binding of ABCA1 and Oas1b 1 0.00 0.13 0
89 INT117795 ABCA1 Regulation of GHRL 1 0.00 0 0
90 INT284393 Positive_regulation of Binding of ABCA1 and Vegfa 1 0.00 0.36 0
91 INT326085 Prkaca Regulation of Phosphorylation of ABCA1 1 0.02 0.44 0
92 INT229981 Binding of ABCA1 and Cdca3 1 0.00 0.74 0
93 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0
94 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0
95 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
96 INT307283 Binding of ABCA1 and PMP2 1 0.00 0 0
97 INT326084 Prkaca Positive_regulation of Phosphorylation of ABCA1 1 0.06 0.44 0
98 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
99 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0
100 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0
101 INT341540 Positive_regulation of F2RL1 Positive_regulation of Gene_expression of AREG 1 0.18 0.51 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for interleukin-1 beta secretion. They are ordered first by their pain relevance and then by number of times they were reported in interleukin-1 beta secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT100733 Positive_regulation of F2RL1 62 0.70 59.14 35.22
2 INT94658 Positive_regulation of F2rl1 51 0.70 33.65 27.46
3 INT90849 Gene_expression of F2rl1 55 0.78 31.31 20.65
4 INT100732 Gene_expression of F2RL1 55 0.78 38.89 19.45
5 INT104674 Positive_regulation of F2rl1 35 0.65 27.76 14.16
6 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
7 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
8 INT103791 Positive_regulation of Positive_regulation of F2rl1 10 0.50 11.24 7.41
9 INT118516 Positive_regulation of Positive_regulation of F2RL1 7 0.49 4.63 6.33
10 INT90848 Localization of F2rl1 23 0.80 3.15 5.2
11 INT105256 Positive_regulation of Gene_expression of F2rl1 6 0.68 10.09 4.83
12 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
13 INT107860 Positive_regulation of Gene_expression of F2RL1 10 0.68 6.36 3.88
14 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
15 INT100729 Localization of F2RL1 7 0.75 5.29 3.37
16 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
17 INT224481 Regulation of F2RL1 4 0.37 5.07 2.74
18 INT161942 Regulation of Gene_expression of F2RL1 12 0.62 4.84 2.73
19 INT111017 Regulation of F2rl1 3 0.22 0 2.61
20 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
21 INT111016 Gene_expression of F2rl1 11 0.73 3.58 2.37
22 INT138331 Binding of F2rl1 4 0.36 1.92 2.32
23 INT114433 Positive_regulation of Positive_regulation of F2rl1 4 0.49 3.5 2.29
24 INT224480 Binding of F2RL1 5 0.36 5.2 2.19
25 INT111018 Binding of F2rl1 5 0.30 3.11 2.02
26 INT224496 Negative_regulation of F2RL1 3 0.48 1.85 1.97
27 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
28 INT96651 Negative_regulation of F2rl1 4 0.37 2.26 1.4
29 INT119743 Negative_regulation of Positive_regulation of F2rl1 3 0.43 1.97 1.3
30 INT327936 Regulation of Gene_expression of F2rl1 1 0.61 2.62 1.26
31 INT224494 Regulation of Positive_regulation of F2RL1 4 0.37 1.67 1.11
32 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
33 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
34 INT159330 Positive_regulation of Localization of F2rl1 1 0.49 0.34 1.02
35 INT112311 Regulation of F2rl1 2 0.27 0.73 0.97
36 INT224489 Negative_regulation of Gene_expression of F2RL1 3 0.57 1.51 0.96
37 INT101495 Regulation of Positive_regulation of F2rl1 1 0.26 0.88 0.91
38 INT190089 Binding of Abca1 5 0.36 2.21 0.83
39 INT164627 Positive_regulation of Gene_expression of ABCA1 9 0.61 3.95 0.67
40 INT292595 Negative_regulation of Positive_regulation of F2RL1 3 0.40 1.29 0.63
41 INT100730 Positive_regulation of Localization of F2RL1 2 0.49 0.99 0.62
42 INT297831 Protein_catabolism of F2rl1 2 0.10 0.5 0.6
43 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56
44 INT124290 Negative_regulation of Gene_expression of F2rl1 3 0.42 1.48 0.52
45 INT111019 Negative_regulation of Binding of F2rl1 1 0.35 0 0.48
46 INT167468 Regulation of Gene_expression of ABCA1 5 0.52 0.08 0.43
47 INT156226 Transcription of F2rl1 1 0.23 1.25 0.41
48 INT166066 Negative_regulation of Localization of F2rl1 1 0.43 0.47 0.4
49 INT156230 Positive_regulation of Binding of F2rl1 1 0.21 1.11 0.4
50 INT209180 Transcription of ABCA1 4 0.47 1.09 0.39
51 INT345322 Regulation of Transcription of ABCA1 1 0.01 0 0.39
52 INT112310 Negative_regulation of Regulation of F2rl1 1 0.03 0 0.39
53 INT167122 Protein_catabolism of ABCA1 3 0.02 0.27 0.37
54 INT292591 Negative_regulation of Negative_regulation of F2RL1 1 0.35 0 0.36
55 INT239295 Positive_regulation of Abca1 3 0.30 2.18 0.32
56 INT239279 Regulation of Gene_expression of Abca1 2 0.44 2.42 0.26
57 INT344685 Positive_regulation of Binding of Abca1 1 0.12 0.76 0.26
58 INT224491 Transcription of F2RL1 1 0.68 0.31 0.26
59 INT94657 Transcription of F2rl1 1 0.69 0.5 0.26
60 INT105257 Regulation of Localization of F2rl1 1 0.23 0 0.26
61 INT284385 Positive_regulation of Localization of ABCA1 2 0.02 0.22 0.25
62 INT239287 Transcription of Abca1 1 0.32 1.87 0.21
63 INT300227 Positive_regulation of Binding of ABCA1 1 0.41 1.85 0.19
64 INT277709 Regulation of Binding of ABCA1 1 0.04 0.52 0.19
65 INT239308 Positive_regulation of Transcription of Abca1 1 0.28 0.67 0.18
66 INT207129 Localization of F2rl1 1 0.22 0.72 0.18
67 INT217387 Regulation of Abca1 3 0.27 2.01 0.15
68 INT292590 Positive_regulation of Negative_regulation of F2RL1 1 0.38 0 0.15
69 INT341581 Positive_regulation of Transcription of F2RL1 1 0.44 0 0.11
70 INT286451 Gene_expression of AIM2 2 0.43 0.1 0.1
71 INT42227 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0 0.09
72 INT42226 Positive_regulation of Positive_regulation of ABCA1 1 0.02 0 0.09
73 INT262061 Negative_regulation of Gene_expression of Abca1 1 0.19 0.68 0.08
74 INT292586 Phosphorylation of F2RL1 1 0.51 0 0.07
75 INT292582 Negative_regulation of Phosphorylation of F2RL1 1 0.35 0 0.07
76 INT239296 Negative_regulation of Abca1 3 0.26 3.83 0.04
77 INT253595 Localization of Abca1 2 0.37 0.35 0.03
78 INT336402 Transcription of AIM2 1 0.23 0.85 0.03
79 INT326077 Positive_regulation of Transcription of ABCA1 1 0.41 0.22 0
80 INT326076 Phosphorylation of ABCA1 1 0.73 0.66 0
81 INT149028 Positive_regulation of Gene_expression of F2rl1 1 0.43 0 0
82 INT149032 Regulation of Gene_expression of F2rl1 1 0.23 0 0
83 INT326083 Positive_regulation of Phosphorylation of ABCA1 1 0.61 0.66 0
84 INT292596 Positive_regulation of Binding of F2RL1 1 0.41 0 0
85 INT308544 Positive_regulation of Gene_expression of AIM2 1 0.32 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox