GO:0050790

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Name regulation of catalytic activity
Categary Process
Go Slim No
Go Link GO:0050790
Unique Molecular Interactions 1314
Total Molecular Interactions 1715
Total Single Events 14097
Pain Genes Associated 63

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of catalytic activity. They are ordered first by their pain relevance and then by number of times they were reported for regulation of catalytic activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
3 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
4 INT226118 Ghrl Regulation of Prkag1 1 0.08 0.72 2.72
5 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
6 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08
7 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76
8 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
9 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
10 INT211744 Binding of Gopc and Mors1 1 0.10 0.2 1.48
11 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
12 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43
13 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
14 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
15 INT229496 Binding of Ndel1 and Gopc 1 0.08 2.05 1.36
16 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
17 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
18 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
19 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
20 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
21 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
22 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
23 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17
24 INT336559 SLC6A3 Positive_regulation of GOPC 1 0.08 1 1.15
25 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
26 INT266742 GOPC Regulation of Positive_regulation of ACR 1 0.02 0.36 1.05
27 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
28 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
29 INT226128 Positive_regulation of Ghrl Regulation of Prkag1 1 0.06 0.28 0.97
30 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
31 INT264924 Binding of Pag1 and Gopc 1 0.06 0.19 0.94
32 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
33 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
34 INT306823 Binding of E2F4 and GOPC 1 0.06 0.23 0.91
35 INT151630 Il1rn Negative_regulation of Dock9 1 0.03 1.33 0.88
36 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
37 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
38 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
39 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
40 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
41 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
42 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
43 INT269455 Binding of RAB5A and GOPC 1 0.08 0 0.82
44 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
45 INT293011 GPM6A Regulation of GOPC 1 0.00 0 0.81
46 INT296786 Gopc Regulation of Positive_regulation of Il1 1 0.02 1.37 0.77
47 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77
48 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
49 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
50 INT269454 Positive_regulation of Binding of GOPC and HHIP 1 0.01 0 0.73
51 INT220746 EGF Positive_regulation of Gene_expression of GOPC 1 0.13 0 0.72
52 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
53 INT232613 Gopc Regulation of Cysltr1 1 0.02 0.58 0.68
54 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
55 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
56 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
57 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
58 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
59 INT264946 Binding of FPR1 and GOPC 1 0.08 0.21 0.64
60 INT206206 Binding of Mcf2l and Obfc1 1 0.02 1.11 0.64
61 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
62 INT264952 Binding of GOPC and BOC 1 0.05 0.22 0.64
63 INT112870 Aap Positive_regulation of Gene_expression of Ccnd1 1 0.24 0.34 0.63
64 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
65 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
66 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
67 INT36320 PDYN Negative_regulation of Ctsb 1 0.00 0 0.61
68 INT223864 Tbs1 Positive_regulation of Gopc 1 0.03 0 0.61
69 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
70 INT37555 FDX1 Positive_regulation of Regulation of Avp 1 0.04 0 0.61
71 INT271194 Binding of Bdnf and Gopc 1 0.03 0.49 0.6
72 INT271192 Binding of Gopc and Gtf3a 1 0.00 0.49 0.6
73 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6
74 INT336557 SLC6A3 Positive_regulation of Binding of GOPC 1 0.08 0.5 0.58
75 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
76 INT351581 Binding of ALB and GOPC 1 0.11 0 0.55
77 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55
78 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54
79 INT352891 Binding of ROS1 and GOPC 1 0.09 1.34 0.53
80 INT269449 Positive_regulation of Binding of RAB5A and GOPC 1 0.11 0 0.53
81 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
82 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
83 INT269442 Binding of GOPC and HHIP 1 0.01 0 0.52
84 INT338038 Gopc Regulation of Gene_expression of F2r 1 0.08 0 0.52
85 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
86 INT274945 Binding of Fcgr1 and Gopc 1 0.02 0 0.49
87 INT242600 Binding of Gdnf and Gopc 1 0.06 0 0.49
88 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
89 INT215543 Negative_regulation of Trim33 Negative_regulation of Gopc 1 0.15 0.35 0.48
90 INT342693 Binding of Prkaca and Gopc 1 0.01 0.23 0.48
91 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
92 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
93 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
94 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46
95 INT27064 Kndc1 Positive_regulation of Localization of Oxt 1 0.00 0 0.46
96 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
97 INT27065 Kndc1 Positive_regulation of Localization of Avp 1 0.00 0 0.46
98 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
99 INT341226 Gopc Regulation of Shc3 1 0.00 0.68 0.45
100 INT208910 Ubl4 Regulation of Regulation of FDX1 1 0.01 0.85 0.45
101 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
102 INT341211 Gopc Regulation of Shc1 1 0.02 0.68 0.45
103 INT226126 Negative_regulation of Ghrl Regulation of Prkag1 1 0.06 0.17 0.45
104 INT252425 Positive_regulation of AR Positive_regulation of Gene_expression of CXCL10 1 0.00 0.9 0.44
105 INT264945 GOPC Positive_regulation of Positive_regulation of FPR1 1 0.10 0.2 0.44
106 INT253145 Il6 Positive_regulation of Prkag1 1 0.11 0.73 0.44
107 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
108 INT257806 Binding of Car1 and Gopc 1 0.13 0 0.43
109 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
110 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
111 INT347563 Abat Positive_regulation of Gopc 1 0.04 0.2 0.43
112 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
113 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
114 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
115 INT226127 Regulation of Ghrl Regulation of Prkag1 1 0.05 0.07 0.42
116 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
117 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
118 INT288162 Igh-Dex Positive_regulation of Gopc 1 0.02 0.63 0.41
119 INT335643 CTSB Positive_regulation of PAR4 1 0.01 1.3 0.41
120 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
121 INT253482 H37 Positive_regulation of Gene_expression of Gopc 1 0.00 3.99 0.4
122 INT356199 GOPC Positive_regulation of Acot7 1 0.04 0.33 0.4
123 INT226129 Ghrl Regulation of Localization of Prkag1 1 0.05 0.07 0.4
124 INT316632 Dao Negative_regulation of Gopc 1 0.09 0 0.4
125 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4
126 INT338085 Binding of PYCARD and GOPC 1 0.05 0 0.39
127 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
128 INT219684 Binding of MMP12 and GOPC 1 0.09 3.11 0.38
129 INT183645 Ppp1r14b Positive_regulation of Macf1 1 0.00 1.23 0.38
130 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
131 INT219683 Binding of CEL and GOPC 1 0.04 3.11 0.38
132 INT183646 Negative_regulation of Ppp1r14b Positive_regulation of Macf1 1 0.00 1.29 0.38
133 INT187521 ATIC Positive_regulation of Prkag1 1 0.01 1.07 0.37
134 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
135 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
136 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
137 INT324819 Hmgb1 Positive_regulation of Gene_expression of Maob 1 0.09 0.44 0.37
138 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
139 INT293201 GOPC Positive_regulation of Gene_expression of IFN1@ 1 0.14 0.18 0.36
140 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
141 INT250252 Binding of SLC1A2 and GOPC 1 0.05 0.44 0.35
142 INT250242 Binding of AQP4 and GOPC 1 0.06 0.39 0.35
143 INT250254 Binding of SLC1A3 and GOPC 1 0.02 0.44 0.35
144 INT226120 Cnr1 Positive_regulation of Prkag1 1 0.09 0 0.35
145 INT252453 Binding of AR and Adora2b 1 0.05 0 0.35
146 INT306822 Binding of E2F2 and GOPC 1 0.05 0.53 0.35
147 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34
148 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34
149 INT224822 Binding of ENOX1 and GOPC 1 0.00 0.34 0.34
150 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
151 INT37554 Avp Regulation of FDX1 1 0.01 0 0.34
152 INT37553 Crh Regulation of FDX1 1 0.03 0 0.34
153 INT356366 S1pr1 Regulation of Gopc 1 0.19 1.22 0.33
154 INT88252 Binding of RAP1A and Krit1 1 0.36 2.25 0.33
155 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
156 INT75641 AR Positive_regulation of Positive_regulation of EIF2B3 1 0.02 0 0.33
157 INT326089 Gopc Positive_regulation of Mmp9 1 0.03 0.63 0.33
158 INT344923 Binding of CEBPZ and GOPC 1 0.06 0.24 0.33
159 INT226124 Ghrl Positive_regulation of Prkag1 1 0.06 0.24 0.33
160 INT263090 Negative_regulation of Binding of FDX1 and LH 1 0.02 0.95 0.32
161 INT263091 Binding of FDX1 and LH 1 0.02 0.95 0.32
162 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
163 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
164 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
165 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
166 INT315387 Adcyap1 Positive_regulation of Phosphorylation of Gopc 1 0.03 0.44 0.32
167 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
168 INT304277 CCNE1 Positive_regulation of IL1RN 1 0.00 1.93 0.31
169 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
170 INT253469 H37 Negative_regulation of Gene_expression of Gopc 1 0.00 1.5 0.31
171 INT304278 CCNE1 Positive_regulation of IL8 1 0.02 1.93 0.31
172 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
173 INT304280 CCNE1 Positive_regulation of IL6 1 0.00 1.93 0.31
174 INT272724 Ptger2 Positive_regulation of Positive_regulation of Gopc 1 0.01 0 0.3
175 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
176 INT272736 Ptger2 Positive_regulation of Gene_expression of Gopc 1 0.01 0 0.3
177 INT264804 Binding of CNNM2 and GOPC 1 0.00 0.18 0.3
178 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
179 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
180 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
181 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
182 INT50107 Ei24 Positive_regulation of Localization of CTSB 3 0.00 0.6 0.29
183 INT187110 Binding of TIMP2 and GOPC 1 0.07 0.64 0.29
184 INT334670 Gria2 Regulation of Gene_expression of Gopc 1 0.31 0.27 0.29
185 INT327706 Comt Regulation of Gopc 1 0.10 0 0.29
186 INT266766 Binding of PGR and GOPC 1 0.00 1.08 0.29
187 INT228530 Gopc Positive_regulation of Gene_expression of Nos2 2 0.22 0.67 0.28
188 INT187147 Positive_regulation of Binding of CXCL10 and GOPC 1 0.08 0.53 0.28
189 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
190 INT291201 Regulation of INS Positive_regulation of GOPC 1 0.00 0.35 0.28
191 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
192 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
193 INT352894 Negative_regulation of Binding of ROS1 and GOPC 1 0.08 0.67 0.28
194 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
195 INT174311 Binding of Krit1 and Rap1a 1 0.04 1.08 0.28
196 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
197 INT291200 INS Positive_regulation of GOPC 1 0.01 0.3 0.28
198 INT258858 CTSB Positive_regulation of Gene_expression of IL8 1 0.00 0.64 0.28
199 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
200 INT187143 Binding of CXCL10 and GOPC 1 0.06 0.53 0.28

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of catalytic activity. They are ordered first by their pain relevance and then by number of times they were reported in regulation of catalytic activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55
2 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6
3 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67
4 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
5 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75
6 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4
7 INT173693 Localization of Gopc 249 0.65 70.49 38.81
8 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
9 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
10 INT15610 Localization of GOPC 223 0.65 68.26 28.7
11 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
12 INT172458 Regulation of Gopc 155 0.53 62.57 24.86
13 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
14 INT170444 Binding of Gopc 172 0.39 45.05 20.71
15 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
16 INT105021 Binding of GOPC 187 0.40 60.39 20.38
17 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
18 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
19 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93
20 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
21 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
22 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
23 INT171666 Regulation of GOPC 117 0.39 40.41 15.47
24 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41
25 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
26 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
27 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
28 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
29 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68
30 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
31 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
32 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
33 INT178306 Negative_regulation of Gene_expression of Gopc 71 0.37 26.43 9.74
34 INT35366 Binding of AR 87 0.47 30.52 8.9
35 INT3622 Regulation of CTSB 34 0.58 16.08 8.76
36 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
37 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
38 INT175526 Phosphorylation of Gopc 73 0.53 21.08 7.86
39 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
40 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
41 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
42 INT7168 Positive_regulation of Ctsb 9 0.70 0.3 7.58
43 INT200874 Positive_regulation of Localization of Gopc 27 0.38 5.69 7.5
44 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
45 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
46 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
47 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34
48 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
49 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
50 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
51 INT127203 Positive_regulation of Mcf2l 14 0.43 9.84 7.03
52 INT170381 Transcription of Gopc 59 0.60 15.96 6.82
53 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
54 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
55 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
56 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
57 INT170296 Regulation of Gene_expression of Gopc 33 0.38 12.49 6
58 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
59 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
60 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
61 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
62 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
63 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
64 INT60585 Regulation of TP53 59 0.59 54.55 5.21
65 INT50105 Localization of CTSB 29 0.78 10.98 5.21
66 INT99091 Regulation of AR 70 0.45 31.68 5.05
67 INT20944 Gene_expression of Mcf2l 13 0.58 5.96 4.76
68 INT7170 Positive_regulation of Positive_regulation of Ctsb 1 0.40 0 4.76
69 INT178754 Positive_regulation of Localization of GOPC 32 0.43 10.1 4.73
70 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
71 INT121608 Positive_regulation of Prkag1 23 0.15 9.35 4.64
72 INT5205 Localization of AR 43 0.80 12.87 4.63
73 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
74 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
75 INT170604 Negative_regulation of Gene_expression of GOPC 50 0.35 12.71 4.51
76 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
77 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
78 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
79 INT105974 Positive_regulation of PRKAB1 43 0.67 23.47 4.16
80 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15
81 INT127202 Negative_regulation of Mcf2l 8 0.50 6.7 4.15
82 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13
83 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4
84 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92
85 INT146350 Phosphorylation of Rgs14 1 0.80 0.79 3.77
86 INT174277 Positive_regulation of Positive_regulation of Gopc 23 0.33 8.08 3.73
87 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
88 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71
89 INT170899 Negative_regulation of Positive_regulation of Gopc 16 0.19 5.46 3.71
90 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
91 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
92 INT137702 Binding of TTN 7 0.35 4.48 3.62
93 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6
94 INT175531 Positive_regulation of Phosphorylation of Gopc 11 0.33 2.53 3.54
95 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
96 INT20265 Gene_expression of Ctsb 3 0.47 1.01 3.52
97 INT151586 Positive_regulation of Prkag1 51 0.54 18.7 3.34
98 INT170606 Regulation of Gene_expression of GOPC 31 0.37 6.08 3.31
99 INT200872 Negative_regulation of Localization of Gopc 16 0.22 5.61 3.3
100 INT127200 Localization of Mcf2l 7 0.64 4.8 3.25
101 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
102 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
103 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
104 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
105 INT105884 Binding of Bcl2 19 0.35 15.67 3
106 INT180971 Protein_catabolism of GOPC 21 0.77 6.15 2.98
107 INT8103 Binding of TP53 46 0.44 40.2 2.96
108 INT175524 Negative_regulation of Phosphorylation of Gopc 14 0.20 2.74 2.96
109 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
110 INT110980 Gene_expression of CTSB 17 0.45 8.02 2.69
111 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
112 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66
113 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
114 INT169987 Transcription of GOPC 45 0.60 21.88 2.61
115 INT169798 Positive_regulation of Rapgef3 1 0.45 1.7 2.56
116 INT73028 Positive_regulation of Transcription of Ctsb 1 0.55 1.53 2.54
117 INT59135 Positive_regulation of CTSB 15 0.67 7.53 2.53
118 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
119 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5
120 INT208898 Gene_expression of FDX1 8 0.10 5.58 2.39
121 INT55952 Transcription of TP53 16 0.61 12.14 2.36
122 INT37427 Positive_regulation of Gene_expression of Ctsb 2 0.37 1.02 2.33
123 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
124 INT7173 Regulation of Positive_regulation of Ctsb 1 0.49 0 2.29
125 INT174979 Phosphorylation of GOPC 45 0.51 10.11 2.28
126 INT93396 Positive_regulation of Gene_expression of Ccnd1 13 0.52 8.59 2.26
127 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
128 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
129 INT109334 Regulation of SOD2 13 0.60 7.48 2.14
130 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
131 INT93398 Negative_regulation of Gene_expression of Ccnd1 5 0.44 2.61 2.12
132 INT162669 Regulation of Prkag1 4 0.09 3.77 2.1
133 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08
134 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
135 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
136 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
137 INT65855 Localization of TP53 18 0.76 17.08 1.89
138 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
139 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
140 INT148493 Regulation of Mnat1 2 0.23 0.8 1.86
141 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
142 INT253755 Regulation of Hmgb1 7 0.55 6.23 1.8
143 INT112867 Positive_regulation of Gene_expression of Ccnd1 15 0.56 13.22 1.77
144 INT162670 Gene_expression of Prkag1 5 0.22 4.45 1.73
145 INT207202 Positive_regulation of Transcription of Gopc 10 0.16 1.76 1.71
146 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69
147 INT50106 Positive_regulation of Localization of CTSB 9 0.33 3.15 1.69
148 INT73027 Transcription of Ctsb 1 0.56 1.01 1.68
149 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
150 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
151 INT106534 Gene_expression of Dock9 3 0.65 1.62 1.63
152 INT126276 Regulation of Rgs14 1 0.39 0.71 1.63
153 INT10598 Gene_expression of Ar 10 0.64 3.44 1.61
154 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59
155 INT200873 Positive_regulation of Negative_regulation of Gopc 4 0.36 0.81 1.59
156 INT230716 Regulation of Binding of GOPC 2 0.10 0.26 1.59
157 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
158 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
159 INT32040 Positive_regulation of CPN2 6 0.35 0.67 1.53
160 INT124299 Negative_regulation of Gene_expression of Sod2 15 0.53 13.8 1.51
161 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
162 INT178615 Binding of SOD2 12 0.48 6.93 1.51
163 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5
164 INT143443 Localization of HIF1A 14 0.78 10.93 1.49
165 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
166 INT169799 Binding of Rapgef3 1 0.30 1.04 1.43
167 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
168 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
169 INT172953 Binding of Trp53 33 0.37 20.76 1.41
170 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
171 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
172 INT151588 Phosphorylation of Prkag1 48 0.73 15.62 1.38
173 INT42335 Binding of CTSB 11 0.34 5.98 1.37
174 INT145221 Binding of Tp53 10 0.37 8.59 1.37
175 INT82932 Transcription of AR 14 0.67 5.75 1.34
176 INT32118 Regulation of Mcf2l 6 0.39 3.05 1.34
177 INT130998 Regulation of PRKAB1 11 0.45 5.7 1.33
178 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
179 INT68500 Regulation of Ar 6 0.27 4.16 1.32
180 INT108327 Negative_regulation of Gene_expression of Ccnd1 18 0.38 14.36 1.31
181 INT104636 Regulation of TTN 2 0.33 0 1.29
182 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
183 INT170900 Regulation of Positive_regulation of Gopc 10 0.20 3.44 1.24
184 INT146351 Positive_regulation of Phosphorylation of Rgs14 1 0.45 0.27 1.23
185 INT181003 Negative_regulation of Localization of GOPC 11 0.30 1.93 1.22
186 INT188396 Positive_regulation of Positive_regulation of GOPC 13 0.42 1.78 1.21
187 INT213379 Phosphorylation of AR 6 0.63 2.03 1.21
188 INT215091 Regulation of Localization of Gopc 6 0.27 1.18 1.2
189 INT134061 Transcription of Sod2 5 0.68 3.46 1.19
190 INT174156 Localization of Trp53 16 0.72 13.52 1.18
191 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
192 INT128987 Negative_regulation of Ccnd1 24 0.52 15.78 1.15
193 INT16157 Gene_expression of CPN2 4 0.26 0 1.14
194 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
195 INT20317 Localization of Ctsb 3 0.81 0.68 1.12
196 INT59136 Negative_regulation of Positive_regulation of CTSB 3 0.41 2.02 1.11
197 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
198 INT144427 Transcription of Ccnd1 10 0.41 7.89 1.07
199 INT226111 Gene_expression of Prkag1 24 0.45 9.76 1.05
200 INT215077 Negative_regulation of Positive_regulation of Hmgb1 3 0.42 5.09 1.05
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