GO:0050820

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Name positive regulation of coagulation
Categary Process
Go Slim No
Go Link GO:0050820
Unique Molecular Interactions 83
Total Molecular Interactions 119
Total Single Events 1414
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of coagulation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of coagulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
2 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
3 INT130355 spc Regulation of Serpine1 1 0.14 0.2 0.66
4 INT130354 Adcy10 Regulation of Serpine1 1 0.17 0.2 0.66
5 INT92803 Binding of CYP1A2 and VKORC1 1 0.31 0.12 0.48
6 INT92804 Positive_regulation of Binding of CYP1A2 and VKORC1 1 0.41 0.12 0.48
7 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
8 INT126531 Adra1a Positive_regulation of Serpine1 1 0.03 0.31 0.34
9 INT15685 Binding of PLAT and Serpine1 3 0.36 1.01 0.31
10 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
11 INT230751 Agtr2 Positive_regulation of Gene_expression of Serpine1 1 0.03 1.3 0.23
12 INT255257 Binding of Serpine1 and Tsp1 1 0.07 0.85 0.2
13 INT115006 Binding of Serpine1 and Cpb2 1 0.09 1.53 0.2
14 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
15 INT97820 Serpine1 Negative_regulation of TIMP1 1 0.00 0.29 0.17
16 INT158613 Binding of Serpine1 and Vtn 1 0.02 0.95 0.16
17 INT294207 Serpine1 Regulation of Gene_expression of Plat 1 0.50 0.92 0.16
18 INT180671 Binding of Plat and Regulation of Serpine1 1 0.16 0.06 0.14
19 INT94763 PSEN2 Regulation of Positive_regulation of App 1 0.11 0.72 0.14
20 INT300513 Binding of Serpine1 and Vtn 1 0.17 2.27 0.13
21 INT294208 Gene_expression of Serpine1 Negative_regulation of Plat 1 0.47 0.94 0.12
22 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
23 INT158615 Binding of Serpine1 and Plaur 1 0.04 0.38 0.1
24 INT158614 Negative_regulation of Binding of Serpine1 and Vtn 1 0.03 0.48 0.09
25 INT230746 Crp Positive_regulation of Localization of Serpine1 1 0.16 0.27 0.09
26 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
27 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
28 INT239237 TCN2 Positive_regulation of Gene_expression of Serpine1 1 0.00 0.68 0.08
29 INT294220 INCENP Positive_regulation of Gene_expression of Serpine1 1 0.00 0.41 0.08
30 INT58649 Binding of INS and Serpine1 1 0.01 1.64 0.07
31 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
32 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
33 INT344703 Hdl1 Negative_regulation of Gene_expression of Serpine1 1 0.07 1.26 0.05
34 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05
35 INT193970 Binding of PSEN1 and Psen2 1 0.36 2.06 0.05
36 INT213037 Hdl1 Positive_regulation of Gene_expression of Serpine1 1 0.19 1.19 0.04
37 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04
38 INT331477 PSEN2 Regulation of Gene_expression of Psen1 1 0.00 0.15 0.03
39 INT348694 Atp9a Negative_regulation of Serpine1 1 0.00 0.24 0.03
40 INT354896 Binding of Psen2 and Fancd2 1 0.04 0.75 0.03
41 INT331478 Psen1 Regulation of Gene_expression of PSEN2 1 0.00 0.15 0.03
42 INT254867 Ctgf Negative_regulation of Serpine1 1 0.04 0.51 0.03
43 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
44 INT120661 Positive_regulation of Plg Positive_regulation of Serpine1 1 0.00 0 0
45 INT143067 Mthfd1 Positive_regulation of Serpine1 1 0.00 0 0
46 INT193962 Binding of Psen1 and Ncstn 1 0.13 0.08 0
47 INT334644 Binding of PSEN1 and TTN 1 0.01 0 0
48 INT350098 Gene_expression of PSEN2 Positive_regulation of Gene_expression of Hmox1 1 0.39 0 0
49 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0
50 INT294205 Serpine1 Negative_regulation of Plat 1 0.47 0.51 0
51 INT223283 Binding of CYP2C9 and VKORC1 1 0.31 0.16 0
52 INT217398 Binding of Psen2 and Bace1 1 0.12 1.44 0
53 INT294204 Binding of Serpine1 and Plat 1 0.46 0.2 0
54 INT193955 Binding of Psen1 and Psen2 1 0.37 1.64 0
55 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
56 INT286331 Binding of Psen1 and Ror1 1 0.27 0 0
57 INT251893 Serpine1 Negative_regulation of Plau 1 0.39 0.6 0
58 INT193968 Binding of PSEN1 and Ps 1 0.07 0.66 0
59 INT78416 Binding of Serpine1 and Vwf 1 0.00 0.11 0
60 INT262712 Psen1 Regulation of Gene_expression of Bace1 1 0.22 0.07 0
61 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0
62 INT286337 PSENEN Regulation of Psen1 1 0.07 0.37 0
63 INT143065 Mthfd1 Positive_regulation of Gene_expression of Serpine1 1 0.00 0 0
64 INT193958 Binding of Pld1 and Psen1 1 0.17 0 0
65 INT251891 Serpine1 Negative_regulation of Plg 1 0.12 3.13 0
66 INT193953 Binding of Bcl2l1 and Psen1 1 0.07 0.66 0
67 INT130223 Binding of Serpinc1 and Serpine1 1 0.00 0.13 0
68 INT193956 Binding of Psen1 and Rab6a 1 0.15 0 0
69 INT115465 Binding of Serpine1 and Plau 1 0.00 0.05 0
70 INT294428 PSEN2 Regulation of Gene_expression of Tp53 1 0.49 0.86 0
71 INT294429 PSEN2 Negative_regulation of Tp53 1 0.46 1.03 0
72 INT193957 Binding of Bcl2l1 and Psen2 1 0.07 0.66 0
73 INT331479 Binding of PSEN2 and Psen1 1 0.00 0.07 0
74 INT120660 Plg Positive_regulation of Serpine1 1 0.00 0 0
75 INT57791 Binding of Serpine1 and Plat 1 0.00 0.07 0
76 INT234221 Negative_regulation of PSEN1 Negative_regulation of Gene_expression of APP 1 0.33 0.32 0
77 INT334645 Binding of PSEN1 and HM13 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of coagulation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of coagulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
2 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67
3 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4
4 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61
5 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
6 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72
7 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
8 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
9 INT15941 Negative_regulation of Serpine1 42 0.58 21.07 4.95
10 INT15920 Regulation of Serpine1 34 0.42 17.36 4.89
11 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
12 INT17548 Negative_regulation of Serpine1 30 0.57 24.69 3.93
13 INT16263 Regulation of Serpine1 13 0.45 5.24 3.6
14 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
15 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
16 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
17 INT163544 Binding of Psen1 40 0.36 15.28 2.42
18 INT15922 Positive_regulation of Positive_regulation of Serpine1 6 0.31 8.34 2.16
19 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
20 INT60723 Localization of Psen2 5 0.68 2.11 2.02
21 INT71115 Positive_regulation of Gene_expression of Serpine1 20 0.70 15.32 1.97
22 INT23188 Localization of Serpine1 22 0.79 16.06 1.96
23 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
24 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
25 INT122058 Negative_regulation of VKORC1 1 0.39 0.18 1.63
26 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
27 INT78646 Regulation of Psen2 4 0.20 1.78 1.42
28 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
29 INT24685 Localization of Serpine1 12 0.59 7.76 1.32
30 INT128061 Negative_regulation of Gene_expression of Serpine1 16 0.43 13.13 1.29
31 INT20100 Binding of Serpine1 16 0.29 6.78 1.18
32 INT15919 Positive_regulation of Gene_expression of Serpine1 6 0.41 4.5 1.15
33 INT54137 Positive_regulation of Positive_regulation of Serpine1 4 0.70 0.79 1.06
34 INT78645 Negative_regulation of Gene_expression of Psen2 1 0.14 0.13 1.01
35 INT20156 Positive_regulation of Negative_regulation of Serpine1 4 0.49 2.89 0.97
36 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
37 INT78647 Positive_regulation of Localization of Psen2 1 0.16 0.14 0.83
38 INT122057 Regulation of VKORC1 1 0.18 0.05 0.83
39 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
40 INT112336 Binding of Serpine1 8 0.41 4.62 0.78
41 INT94756 Positive_regulation of PSEN2 8 0.49 4.59 0.77
42 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
43 INT193849 Positive_regulation of Gene_expression of Psen2 5 0.44 4.92 0.76
44 INT78649 Binding of Psen2 7 0.36 5.9 0.73
45 INT78648 Regulation of Binding of Psen2 1 0.14 0.2 0.73
46 INT91765 Positive_regulation of Gene_expression of PSEN2 8 0.49 4.57 0.63
47 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
48 INT20099 Regulation of Positive_regulation of Serpine1 2 0.40 1.75 0.52
49 INT58015 Regulation of Gene_expression of Serpine1 3 0.41 2.61 0.47
50 INT35435 Negative_regulation of Positive_regulation of Serpine1 5 0.42 2.26 0.46
51 INT316041 Transcription of Psen2 1 0.64 1.1 0.45
52 INT20101 Regulation of Positive_regulation of Serpine1 1 0.10 0.94 0.44
53 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
54 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
55 INT193856 Localization of Psen1 19 0.73 9.79 0.41
56 INT36396 Positive_regulation of Psen2 6 0.44 4.57 0.39
57 INT126530 Negative_regulation of Positive_regulation of Serpine1 3 0.43 2.62 0.38
58 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
59 INT187606 Negative_regulation of Gene_expression of Serpine1 3 0.05 1.78 0.36
60 INT200606 Regulation of Gene_expression of Serpine1 4 0.38 2.07 0.35
61 INT261682 Positive_regulation of Positive_regulation of PSEN2 1 0.21 0.55 0.33
62 INT172783 Regulation of Localization of Serpine1 3 0.30 3.83 0.32
63 INT99739 Protein_catabolism of Serpine1 4 0.87 1.71 0.29
64 INT224298 Negative_regulation of PSEN2 6 0.57 2.29 0.28
65 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
66 INT261676 Negative_regulation of Positive_regulation of PSEN1 1 0.36 1.59 0.25
67 INT172525 Localization of PSEN2 5 0.73 4.17 0.24
68 INT125772 Positive_regulation of Negative_regulation of Serpine1 1 0.42 0.4 0.22
69 INT181508 Regulation of Regulation of Psen1 2 0.33 0.51 0.2
70 INT125773 Transcription of Serpine1 4 0.53 2.35 0.19
71 INT25009 Regulation of Localization of Serpine1 2 0.36 0.15 0.17
72 INT286317 Positive_regulation of Transcription of Psen1 1 0.37 0.32 0.17
73 INT82636 Negative_regulation of Localization of Serpine1 1 0.29 1.01 0.16
74 INT212989 Negative_regulation of Localization of Serpine1 1 0.26 2.2 0.16
75 INT212957 Positive_regulation of Localization of Serpine1 2 0.50 1.89 0.15
76 INT336359 Positive_regulation of Phosphorylation of Psen1 1 0.33 0.4 0.13
77 INT336361 Phosphorylation of Psen1 1 0.54 0.34 0.13
78 INT176595 Negative_regulation of Gene_expression of PSEN2 1 0.24 1.01 0.11
79 INT193841 Regulation of Gene_expression of Psen2 1 0.40 1.66 0.11
80 INT201694 Negative_regulation of Gene_expression of PSEN1 3 0.41 2.31 0.1
81 INT51990 Transcription of Serpine1 3 0.45 2.01 0.09
82 INT273285 Negative_regulation of Localization of Psen1 1 0.36 0.99 0.09
83 INT245881 Negative_regulation of Negative_regulation of Serpine1 1 0.04 1.66 0.09
84 INT109131 Regulation of PSEN2 3 0.44 0.55 0.08
85 INT193862 Positive_regulation of Positive_regulation of Psen1 3 0.49 0.9 0.08
86 INT193872 Positive_regulation of Localization of Psen1 3 0.49 1.39 0.08
87 INT261678 Positive_regulation of Positive_regulation of PSEN1 1 0.42 0.62 0.08
88 INT193890 Regulation of Positive_regulation of Psen1 1 0.44 0.66 0.08
89 INT193938 Phosphorylation of PSEN1 5 0.79 1.6 0.07
90 INT176592 Transcription of PSEN2 5 0.33 0.41 0.05
91 INT193859 Negative_regulation of Binding of Psen1 3 0.42 1.85 0.05
92 INT331406 Negative_regulation of Regulation of Psen1 1 0.04 0.09 0.05
93 INT193865 Protein_catabolism of Psen1 10 0.97 0.37 0.04
94 INT254810 Negative_regulation of Protein_catabolism of Serpine1 1 0.08 0.51 0.03
95 INT254787 Positive_regulation of Protein_catabolism of Serpine1 1 0.10 0.52 0.03
96 INT224302 Negative_regulation of Transcription of PSEN2 3 0.26 0.08 0
97 INT265229 Binding of PSEN2 2 0.16 1.37 0
98 INT286327 Regulation of Binding of Psen1 1 0.33 0.16 0
99 INT234250 Positive_regulation of Negative_regulation of PSEN1 1 0.41 0 0
100 INT254802 Phosphorylation of Serpine1 1 0.05 0 0
101 INT193886 Regulation of Protein_catabolism of Psen1 1 0.44 0.06 0
102 INT193934 Positive_regulation of Binding of PSEN1 1 0.49 0.92 0
103 INT224297 Regulation of Transcription of PSEN2 1 0.20 0.06 0
104 INT331407 Negative_regulation of Transcription of Psen1 1 0.04 0.08 0
105 INT66115 Regulation of Binding of Serpine1 1 0.09 0.12 0
106 INT177774 Transcription of PSEN1 1 0.33 0.09 0
107 INT200607 Positive_regulation of Regulation of Serpine1 1 0.42 0.97 0
108 INT353031 Negative_regulation of Transcription of Serpine1 1 0.02 0.69 0
109 INT310172 Positive_regulation of Transcription of Serpine1 1 0.18 1.99 0
110 INT223290 Binding of VKORC1 1 0.39 0.16 0
111 INT310178 Negative_regulation of Transcription of Serpine1 1 0.15 0.98 0
112 INT354892 Negative_regulation of Psen2 1 0.37 0.95 0
113 INT209319 Gene_expression of VKORC1 1 0.01 1.95 0
114 INT193844 Positive_regulation of Protein_catabolism of Psen1 1 0.49 0.05 0
115 INT331463 Regulation of Gene_expression of PSEN2 1 0.04 0 0
116 INT234258 Negative_regulation of Phosphorylation of PSEN1 1 0.35 0.49 0
117 INT143064 Positive_regulation of Localization of Serpine1 1 0.13 0 0
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