GO:0051988

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Name regulation of attachment of spindle microtubules to kinetochore
Categary Process
Go Slim No
Go Link GO:0051988
Unique Molecular Interactions 174
Total Molecular Interactions 207
Total Single Events 1481
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of attachment of spindle microtubules to kinetochore. They are ordered first by their pain relevance and then by number of times they were reported for regulation of attachment of spindle microtubules to kinetochore. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93781 Racgap1 Positive_regulation of Positive_regulation of Gnptab 1 0.02 0.07 1.49
2 INT93782 Racgap1 Positive_regulation of Rgs9 1 0.55 0.07 1.49
3 INT93783 Racgap1 Positive_regulation of Gnptab 1 0.02 0.07 1.49
4 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
5 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 0.02 0.3 1.19
6 INT70289 Atxn2l Positive_regulation of Racgap1 1 0.04 0.29 1.15
7 INT221747 Gtf3a Positive_regulation of Positive_regulation of Racgap1 1 0.00 0.33 1
8 INT65462 Bri3 Negative_regulation of Racgap1 1 0.02 0.39 0.93
9 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
10 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
11 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
12 INT330107 Racgap1 Regulation of Positive_regulation of Nox3 1 0.01 0.87 0.49
13 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
14 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
15 INT330108 Racgap1 Positive_regulation of Cybb 1 0.03 0.86 0.46
16 INT330110 Racgap1 Regulation of Gene_expression of Ros1 1 0.00 1.12 0.41
17 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
18 INT71925 Binding of Ptprs and Positive_regulation of Racgap1 1 0.10 0 0.35
19 INT71924 Ptprs Positive_regulation of Racgap1 1 0.10 0 0.35
20 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 0.01 1.32 0.35
21 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32
22 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
23 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
24 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
25 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31
26 INT63122 Binding of APC and Man2a2 1 0.01 0.15 0.3
27 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
28 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
29 INT269490 Binding of Racgap1 and HHIP 1 0.00 0 0.27
30 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24
31 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24
32 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
33 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
34 INT109408 Negative_regulation of APC Negative_regulation of Positive_regulation of RASGRP1 1 0.06 0.73 0.23
35 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
36 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23
37 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
38 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22
39 INT195663 APC Negative_regulation of Gene_expression of IL6 1 0.16 1.18 0.22
40 INT71923 Ptprs Regulation of Racgap1 1 0.09 0 0.21
41 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2
42 INT231836 Pcdh8 Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
43 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
44 INT334106 APC Negative_regulation of NFKB1 1 0.25 1.37 0.17
45 INT334108 APC Negative_regulation of TNF 1 0.13 1.36 0.17
46 INT354823 IFNA1 Positive_regulation of Racgap1 1 0.00 1.4 0.15
47 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13
48 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
49 INT184603 APC Negative_regulation of Gene_expression of TNF 1 0.09 0.97 0.13
50 INT269491 Racgap1 Negative_regulation of RAB5A 1 0.01 0 0.12
51 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 1 0.33 0.66 0.12
52 INT184608 APC Regulation of Gene_expression of Nppa 1 0.06 1.11 0.12
53 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11
54 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
55 INT262255 Binding of APC and F2R 1 0.05 3 0.1
56 INT202407 Binding of Osm and Racgap1 1 0.04 0.13 0.09
57 INT202399 Binding of Mapk14 and Racgap1 1 0.07 0.13 0.09
58 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08
59 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08
60 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08
61 INT221470 Binding of Racgap1 and Camkk2 1 0.00 0.06 0.05
62 INT221469 Binding of Racgap1 and Rrad 1 0.02 0.06 0.05
63 INT176095 Binding of Apc and EC 1 0.04 0.51 0.05
64 INT120574 Binding of Apc and Egfr 1 0.27 1.02 0.05
65 INT334107 Binding of APC and APCS 1 0.16 1.52 0.04
66 INT215240 Binding of Myo1f and Racgap1 1 0.01 0.77 0.04
67 INT215244 Binding of Racgap1 and Mlph 1 0.04 0.76 0.04
68 INT181083 Binding of Akt1 and Cdc42 1 0.00 0.79 0.03
69 INT241459 Gart Positive_regulation of Racgap1 1 0.01 0 0.03
70 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
71 INT295702 PTGER2 Positive_regulation of Racgap1 1 0.05 0.22 0
72 INT295701 Positive_regulation of Binding of RAC1 and Racgap1 1 0.28 0.16 0
73 INT213034 Hdl1 Positive_regulation of Apc 1 0.08 1.21 0
74 INT295704 Positive_regulation of Binding of RHOA and Racgap1 1 0.15 0.16 0
75 INT326163 Binding of Racgap1 and RAB12 1 0.00 0.68 0
76 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0
77 INT341502 Negative_regulation of Binding of Apc and Pdcd1 1 0.00 0.53 0
78 INT191096 Negative_regulation of Binding of Apc and Esr1 1 0.05 1.07 0
79 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0
80 INT301675 Binding of APC and HLA-E 1 0.01 1.48 0
81 INT194333 Binding of MFN2 and Racgap1 1 0.01 0.38 0
82 INT286112 Binding of Apc and Afap1 1 0.05 0.71 0
83 INT249148 Binding of Was and Racgap1 1 0.03 0.18 0
84 INT265233 Binding of APC and FKBP1A 1 0.08 0.41 0
85 INT295700 Binding of RAC1 and Racgap1 1 0.21 0.16 0
86 INT213007 Hdl1 Regulation of Regulation of Apc 1 0.08 1.24 0
87 INT301674 Binding of APC and CD80 1 0.01 0.53 0
88 INT183897 Binding of RHOC and Racgap1 1 0.01 0.2 0
89 INT249149 Binding of Cdc42 and Was 1 0.08 0.18 0
90 INT195661 Binding of APC and PROC 1 0.23 0.89 0
91 INT253019 APC Positive_regulation of Protein_catabolism of Pttg1 1 0.06 0 0
92 INT253012 APC Positive_regulation of Binding of Pttg1 1 0.06 0 0
93 INT268342 Binding of APC and ANKS1B 1 0.01 0.92 0
94 INT191095 Positive_regulation of Binding of Apc and Esr1 1 0.06 1.08 0
95 INT301677 Binding of APC and CD8A 1 0.03 1.48 0
96 INT265232 Regulation of Binding of APC and FKBP1A 1 0.08 0.41 0
97 INT268395 Binding of APC and Kras 1 0.04 1.21 0
98 INT213009 Hdl1 Positive_regulation of Positive_regulation of Apc 1 0.09 1.14 0
99 INT295703 Binding of RHOA and Racgap1 1 0.11 0.16 0
100 INT80660 INS Positive_regulation of APC 1 0.32 0.65 0
101 INT283362 AXIN2 Negative_regulation of APC 1 0.10 1.67 0
102 INT191098 Binding of Apc and Esr1 1 0.04 1.06 0
103 INT195659 APC Positive_regulation of Gene_expression of PROC 1 0.26 0.31 0
104 INT213025 Vtn Positive_regulation of Apc 1 0.01 1.19 0
105 INT213054 Hdl1 Regulation of Apc 1 0.05 1.24 0
106 INT80659 Positive_regulation of INS Positive_regulation of APC 1 0.32 0.65 0
107 INT236721 Binding of Apc and Ctnnd2 1 0.25 1.03 0
108 INT271978 Positive_regulation of Racgap1 Regulation of Mtor 1 0.00 0.54 0
109 INT181085 Binding of Cdc42 and Errfi1 1 0.08 0.67 0
110 INT252909 FZR1 Positive_regulation of APC 1 0.06 0.08 0
111 INT341501 Binding of Apc and Pdcd1 1 0.00 0.52 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of attachment of spindle microtubules to kinetochore. They are ordered first by their pain relevance and then by number of times they were reported in regulation of attachment of spindle microtubules to kinetochore. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29
2 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
3 INT60285 Negative_regulation of Racgap1 27 0.56 21.71 8.14
4 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
5 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
6 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
7 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
8 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
9 INT63121 Binding of APC 29 0.41 23.02 3.8
10 INT52839 Regulation of Racgap1 14 0.25 9.46 3.37
11 INT70286 Negative_regulation of Positive_regulation of Racgap1 2 0.43 3.78 2.42
12 INT54515 Positive_regulation of Positive_regulation of Racgap1 6 0.12 2.33 2.34
13 INT70283 Gene_expression of Racgap1 19 0.44 9.64 2.33
14 INT65459 Binding of Racgap1 9 0.07 4.57 2.28
15 INT3818 Regulation of Apc 13 0.39 12.52 1.68
16 INT220177 Binding of Apc 21 0.37 15.34 1.37
17 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
18 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
19 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15
20 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1
21 INT161682 Positive_regulation of Cdc42 8 0.53 4.55 0.9
22 INT242134 Localization of Apc 8 0.74 4.83 0.88
23 INT330076 Regulation of Positive_regulation of Racgap1 1 0.04 1.98 0.73
24 INT57062 Regulation of APC 24 0.58 14.3 0.7
25 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69
26 INT289327 Regulation of Negative_regulation of Racgap1 2 0.05 2.09 0.62
27 INT180107 Regulation of Cdc42 3 0.16 0.18 0.6
28 INT97956 Negative_regulation of CDC42 3 0.27 1.58 0.55
29 INT72869 Regulation of Negative_regulation of APC 2 0.36 1.7 0.54
30 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46
31 INT199077 Localization of Racgap1 7 0.73 2.43 0.42
32 INT152151 Regulation of Gene_expression of Apc 4 0.44 3.87 0.42
33 INT288080 Regulation of Gene_expression of Racgap1 3 0.04 3.42 0.41
34 INT220170 Regulation of Positive_regulation of Apc 1 0.10 0.46 0.35
35 INT330074 Negative_regulation of Binding of Racgap1 1 0.03 1.47 0.35
36 INT118243 Transcription of APC 4 0.45 3.33 0.33
37 INT184605 Positive_regulation of Transcription of APC 2 0.19 2.39 0.33
38 INT330075 Negative_regulation of Transcription of Racgap1 1 0.03 1.05 0.33
39 INT330077 Transcription of Racgap1 1 0.05 1.04 0.33
40 INT225667 Transcription of Apc 3 0.52 3.73 0.32
41 INT270418 Negative_regulation of Negative_regulation of Racgap1 1 0.02 0.53 0.31
42 INT195672 Localization of APC 7 0.74 3.76 0.3
43 INT183881 Localization of CDC42 3 0.49 1.92 0.23
44 INT225666 Regulation of Transcription of Apc 1 0.29 0.33 0.22
45 INT183876 Regulation of CDC42 3 0.30 1.94 0.19
46 INT173166 Negative_regulation of Binding of APC 3 0.40 3.01 0.19
47 INT57065 Negative_regulation of Positive_regulation of APC 3 0.22 2.43 0.17
48 INT228603 Positive_regulation of Positive_regulation of Apc 1 0.24 0.24 0.17
49 INT197290 Gene_expression of Cdc42 9 0.35 2.52 0.15
50 INT250790 Negative_regulation of Localization of APC 2 0.13 2.3 0.13
51 INT250792 Positive_regulation of Localization of APC 1 0.15 0.48 0.13
52 INT206133 Binding of CDC42 3 0.25 0.8 0.12
53 INT242140 Regulation of Localization of Apc 1 0.12 0.12 0.11
54 INT242819 Negative_regulation of Gene_expression of Apc 4 0.37 5.6 0.1
55 INT268372 Phosphorylation of APC 3 0.81 3.39 0.09
56 INT197282 Positive_regulation of Gene_expression of Cdc42 3 0.26 0.12 0.08
57 INT195679 Positive_regulation of Positive_regulation of APC 6 0.50 4.43 0.05
58 INT235057 Positive_regulation of Negative_regulation of Apc 2 0.30 0.66 0.05
59 INT206169 Gene_expression of CDC42 2 0.26 1.05 0.05
60 INT206167 Positive_regulation of Gene_expression of CDC42 1 0.08 0.05 0.05
61 INT288079 Positive_regulation of Gene_expression of Racgap1 1 0.06 0.74 0.04
62 INT206049 Negative_regulation of Localization of Racgap1 1 0.01 0.12 0.04
63 INT242139 Protein_catabolism of Apc 1 0.17 0.27 0.03
64 INT195681 Positive_regulation of Negative_regulation of APC 5 0.47 3.9 0
65 INT254795 Negative_regulation of Cdc42 2 0.12 1.53 0
66 INT270614 Localization of Cdc42 1 0.55 0.95 0
67 INT197294 Regulation of Gene_expression of Cdc42 1 0.13 0 0
68 INT337657 Negative_regulation of Negative_regulation of APC 1 0.37 0.99 0
69 INT104591 Negative_regulation of Negative_regulation of Apc 1 0.04 0.16 0
70 INT337673 Regulation of Positive_regulation of APC 1 0.38 1.44 0
71 INT282269 Binding of Cdc42 1 0.08 0.33 0
72 INT191087 Regulation of Regulation of Apc 1 0.06 1.02 0
73 INT287281 Positive_regulation of Positive_regulation of CDC42 1 0.26 0 0
74 INT282272 Positive_regulation of Binding of Cdc42 1 0.11 0.33 0
75 INT283365 Positive_regulation of Binding of APC 1 0.50 1.43 0
76 INT337667 Regulation of Transcription of APC 1 0.23 1 0
77 INT286093 Regulation of Binding of Apc 1 0.39 1.08 0
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