GO:0055091

From wiki-pain
Revision as of 17:21, 22 January 2013 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Name phospholipid homeostasis
Categary Process
Go Slim No
Go Link GO:0055091
Unique Molecular Interactions 116
Total Molecular Interactions 145
Total Single Events 939
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phospholipid homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for phospholipid homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
2 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
3 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
4 INT206960 Lipg Regulation of Tnf 1 0.02 0.85 0.51
5 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
6 INT206961 Lipg Regulation of Ptger2 1 0.01 0.85 0.51
7 INT206958 Lipg Regulation of Gene_expression of Ptger2 1 0.01 0.85 0.51
8 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
9 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
10 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
11 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23
12 INT277072 Binding of PLA2G7 and Lipg 1 0.00 1.32 0.21
13 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
14 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
15 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
16 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
17 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
18 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
19 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
20 INT254497 GOPC Regulation of Transcription of HNF4A 1 0.02 0.72 0.16
21 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
22 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
23 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
24 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
25 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
26 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
27 INT239355 Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP 1 0.17 3.75 0.14
28 INT155388 Binding of LPA and Lipg 1 0.00 1.22 0.12
29 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
30 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12
31 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
32 INT313846 Olr407 Negative_regulation of Lipg 1 0.00 0.55 0.09
33 INT42224 ABCA1 Positive_regulation of CYBB 1 0.01 0 0.09
34 INT42225 Binding of ABCA1 and DECR1 1 0.02 0 0.08
35 INT254496 Binding of HNF4A and GOPC 1 0.10 0.34 0.08
36 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07
37 INT315969 Binding of Lipg and Msc 1 0.01 0.14 0.06
38 INT86448 Binding of Cnr1 and Lipg 1 0.28 0.64 0.06
39 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
40 INT262187 Nr1i2 Positive_regulation of Gene_expression of Abcg1 1 0.24 0.21 0.06
41 INT239354 CETP Positive_regulation of Lcat 1 0.28 1.09 0.06
42 INT293233 IDO1 Positive_regulation of ABCA1 1 0.01 0 0.06
43 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05
44 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05
45 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05
46 INT183302 Tchol1 Negative_regulation of Lipg 1 0.00 0.52 0.05
47 INT337386 Lipg Regulation of GK2 1 0.00 0.15 0.05
48 INT296024 Apoa2 Negative_regulation of CETP 1 0.39 0.35 0.05
49 INT290182 Binding of CETP and PLTP 1 0.26 3.31 0.05
50 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05
51 INT239438 Binding of OPA1 and LIPG 1 0.03 1.21 0.04
52 INT239333 Abcg1 Positive_regulation of RCT 1 0.06 1.29 0.03
53 INT230423 INS Negative_regulation of Lipg 1 0.03 0.74 0.03
54 INT230136 OSBPL8 Regulation of Binding of ABCA1 1 0.07 0.17 0.03
55 INT207343 Negative_regulation of CPOX Negative_regulation of Gene_expression of ABCA1 1 0.09 0 0.03
56 INT239351 Binding of CETP and Ldlr 1 0.15 1.01 0.03
57 INT170210 Binding of CETP and HSD11B1 1 0.17 2.58 0
58 INT284392 Binding of ABCA1 and Vegfa 1 0.00 0.71 0
59 INT229927 CD59 Negative_regulation of Binding of ABCA1 1 0.01 0 0
60 INT171598 Binding of APOB and Lipg 1 0.01 0.63 0
61 INT295980 Dap Positive_regulation of Lipg 1 0.17 0.48 0
62 INT229923 Binding of ABCA1 and C9 1 0.00 0.74 0
63 INT287892 PRDX2 Positive_regulation of HNF4A 1 0.00 0.52 0
64 INT219416 CCNA2 Regulation of HNF4A 1 0.00 0.11 0
65 INT235596 HNF4A Regulation of Gene_expression of TPI1 1 0.00 0.25 0
66 INT284372 Binding of ABCA1 and AMT 1 0.00 0 0
67 INT171600 INCENP Negative_regulation of Lipg 1 0.00 0.38 0
68 INT323571 Lipg Positive_regulation of Positive_regulation of Mag 1 0.00 0.15 0
69 INT182952 KCNIP3 Positive_regulation of HNF4A 1 0.02 0.45 0
70 INT287882 Binding of CREBBP and HNF4A 1 0.01 0.85 0
71 INT206959 Lipg Regulation of Cat 1 0.02 0.5 0
72 INT258725 Binding of GPD1 and Lipg 1 0.12 0.13 0
73 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0
74 INT182922 FRA8E Positive_regulation of HNF4A 1 0.00 0.2 0
75 INT297056 Binding of ABCA1 and Oas1b 1 0.00 0.13 0
76 INT307214 Hnf4a Regulation of Ppara 1 0.18 0.35 0
77 INT117795 ABCA1 Regulation of GHRL 1 0.00 0 0
78 INT182926 VDR Positive_regulation of HNF4A 1 0.02 0.09 0
79 INT326836 Binding of HNF4A and PLD2 1 0.03 0.35 0
80 INT197725 Negative_regulation of CETP Positive_regulation of Positive_regulation of HSD11B1 1 0.11 1.15 0
81 INT197726 Negative_regulation of CETP Positive_regulation of HSD11B1 1 0.11 0.76 0
82 INT170213 CETP Positive_regulation of Gene_expression of HSD11B1 1 0.21 1.49 0
83 INT284393 Positive_regulation of Binding of ABCA1 and Vegfa 1 0.00 0.36 0
84 INT219410 CCNF Regulation of HNF4A 1 0.01 0.11 0
85 INT326085 Prkaca Regulation of Phosphorylation of ABCA1 1 0.02 0.44 0
86 INT239353 CETP Regulation of Apoa1 1 0.16 0.65 0
87 INT182938 Binding of HNF4A and KCNIP3 1 0.01 0.2 0
88 INT219426 CDK2 Regulation of HNF4A 1 0.01 0.11 0
89 INT229981 Binding of ABCA1 and Cdca3 1 0.00 0.74 0
90 INT219420 CCNE2 Regulation of HNF4A 1 0.00 0.11 0
91 INT173123 Binding of HNF4A and PPARA 1 0.10 0.19 0
92 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0
93 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0
94 INT344711 Nr1h3 Regulation of Abcg1 1 0.03 1.67 0
95 INT183018 Dre Positive_regulation of HNF4A 1 0.00 0.09 0
96 INT170215 CETP Positive_regulation of HSD11B1 1 0.26 1.35 0
97 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
98 INT307283 Binding of ABCA1 and PMP2 1 0.00 0 0
99 INT182957 CDKN1A Negative_regulation of HNF4A 1 0.02 0.11 0
100 INT182927 Binding of HNF4A and HRES1 1 0.00 0 0
101 INT302594 Binding of CETP and Apoa5 1 0.26 0.63 0
102 INT326084 Prkaca Positive_regulation of Phosphorylation of ABCA1 1 0.06 0.44 0
103 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
104 INT258712 Binding of Gpd1 and Lipg 1 0.11 0.14 0
105 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0
106 INT326902 Binding of HNF4A and Tcf4 1 0.02 0.35 0
107 INT171602 APOC3 Negative_regulation of Lipg 1 0.04 0.38 0
108 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0
109 INT206963 Lipg Regulation of Gpx1 1 0.00 0.5 0
110 INT170237 Lpl Regulation of CETP 1 0.02 0.99 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phospholipid homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in phospholipid homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
2 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
3 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24
4 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
5 INT10923 Positive_regulation of Lipg 30 0.50 22.87 4.26
6 INT156416 Gene_expression of Lipg 38 0.67 18.35 4.07
7 INT18515 Gene_expression of Lipg 18 0.66 9.3 3.72
8 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
9 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
10 INT17562 Negative_regulation of Lipg 32 0.51 16.91 3.17
11 INT12237 Positive_regulation of Lipg 19 0.60 11.09 2.92
12 INT49759 Negative_regulation of CETP 43 0.58 52 2.68
13 INT60750 Gene_expression of HNF4A 12 0.65 8.29 2.68
14 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
15 INT22843 Localization of Lipg 5 0.33 1.95 2.12
16 INT4691 Regulation of Lipg 10 0.61 4.7 1.99
17 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
18 INT86446 Protein_catabolism of Lipg 9 0.50 3.52 1.25
19 INT172630 Binding of HNF4A 16 0.05 7.78 1.22
20 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
21 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
22 INT142914 Negative_regulation of Localization of Lipg 1 0.14 0.49 1.04
23 INT172616 Regulation of HNF4A 9 0.06 4.25 1.02
24 INT52113 Gene_expression of CETP 25 0.69 25.71 0.99
25 INT190089 Binding of Abca1 5 0.36 2.21 0.83
26 INT207565 Negative_regulation of LIPG 8 0.10 7.83 0.76
27 INT169652 Positive_regulation of Protein_catabolism of Lipg 1 0.28 0.07 0.72
28 INT164627 Positive_regulation of Gene_expression of ABCA1 9 0.61 3.95 0.67
29 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56
30 INT174813 Localization of LIPG 3 0.05 1.18 0.55
31 INT21871 Binding of Lipg 4 0.14 0.78 0.53
32 INT48694 Regulation of Gene_expression of Lipg 2 0.21 1.5 0.51
33 INT21339 Phosphorylation of Lipg 1 0.19 0.66 0.51
34 INT239289 Gene_expression of Abcg1 3 0.31 2.27 0.5
35 INT126683 Localization of Lipg 7 0.70 3.87 0.46
36 INT275642 Negative_regulation of HNF4A 4 0.05 2.08 0.44
37 INT167468 Regulation of Gene_expression of ABCA1 5 0.52 0.08 0.43
38 INT18514 Positive_regulation of Positive_regulation of Lipg 1 0.13 0.15 0.43
39 INT209180 Transcription of ABCA1 4 0.47 1.09 0.39
40 INT345322 Regulation of Transcription of ABCA1 1 0.01 0 0.39
41 INT344684 Positive_regulation of Gene_expression of Abcg1 1 0.10 0.95 0.38
42 INT167122 Protein_catabolism of ABCA1 3 0.02 0.27 0.37
43 INT116725 Positive_regulation of CETP 19 0.49 16.33 0.36
44 INT106253 Positive_regulation of HNF4A 14 0.29 3.88 0.34
45 INT199121 Positive_regulation of Gene_expression of Lipg 4 0.13 2.44 0.32
46 INT239295 Positive_regulation of Abca1 3 0.30 2.18 0.32
47 INT3959 Regulation of Lipg 6 0.27 2.48 0.29
48 INT183208 Transcription of HNF4A 7 0.11 3.15 0.28
49 INT77031 Gene_expression of LIPG 4 0.51 4.32 0.26
50 INT239279 Regulation of Gene_expression of Abca1 2 0.44 2.42 0.26
51 INT344685 Positive_regulation of Binding of Abca1 1 0.12 0.76 0.26
52 INT86447 Binding of Lipg 3 0.18 1.51 0.25
53 INT284385 Positive_regulation of Localization of ABCA1 2 0.02 0.22 0.25
54 INT21340 Regulation of Phosphorylation of Lipg 1 0.14 0.35 0.24
55 INT116724 Positive_regulation of Gene_expression of CETP 3 0.41 7.92 0.23
56 INT70647 Regulation of CETP 7 0.61 4.53 0.21
57 INT275639 Positive_regulation of Binding of HNF4A 2 0.04 0.87 0.21
58 INT239287 Transcription of Abca1 1 0.32 1.87 0.21
59 INT60751 Positive_regulation of Gene_expression of HNF4A 2 0.49 3.5 0.19
60 INT300227 Positive_regulation of Binding of ABCA1 1 0.41 1.85 0.19
61 INT277709 Regulation of Binding of ABCA1 1 0.04 0.52 0.19
62 INT42014 Regulation of Localization of Lipg 1 0.16 0.19 0.19
63 INT239308 Positive_regulation of Transcription of Abca1 1 0.28 0.67 0.18
64 INT239307 Positive_regulation of Abcg1 1 0.24 0.73 0.17
65 INT164022 Regulation of Gene_expression of HNF4A 1 0.03 0.82 0.16
66 INT217387 Regulation of Abca1 3 0.27 2.01 0.15
67 INT111337 Protein_catabolism of Lipg 2 0.66 0.43 0.13
68 INT287917 Phosphorylation of HNF4A 1 0.08 0.07 0.13
69 INT217684 Positive_regulation of LIPG 3 0.04 1.9 0.12
70 INT187880 Binding of Abcg1 3 0.33 2.07 0.1
71 INT117686 Regulation of LIPG 2 0.04 0.49 0.1
72 INT212876 Negative_regulation of Gene_expression of Lipg 1 0.06 0.37 0.1
73 INT42227 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0 0.09
74 INT42226 Positive_regulation of Positive_regulation of ABCA1 1 0.02 0 0.09
75 INT229152 Negative_regulation of Abcg1 2 0.19 1.35 0.08
76 INT126667 Localization of HNF4A 2 0.06 0.45 0.08
77 INT262061 Negative_regulation of Gene_expression of Abca1 1 0.19 0.68 0.08
78 INT41694 Transcription of Lipg 1 0.53 0.85 0.08
79 INT239311 Transcription of CETP 1 0.49 1.02 0.06
80 INT239313 Positive_regulation of Transcription of CETP 1 0.35 1.02 0.06
81 INT287925 Regulation of Binding of HNF4A 1 0.06 1.1 0.05
82 INT239296 Negative_regulation of Abca1 3 0.26 3.83 0.04
83 INT312770 Positive_regulation of Negative_regulation of CETP 2 0.12 2.12 0.04
84 INT292414 Regulation of Negative_regulation of Lipg 2 0.09 0.7 0.04
85 INT239315 Negative_regulation of Gene_expression of CETP 1 0.30 1.09 0.04
86 INT206957 Negative_regulation of Gene_expression of Lipg 3 0.08 1.01 0.03
87 INT187421 Binding of CETP 2 0.23 1.34 0.03
88 INT253595 Localization of Abca1 2 0.37 0.35 0.03
89 INT258794 Positive_regulation of Positive_regulation of LIPG 1 0.03 0.57 0.03
90 INT239270 Transcription of Abcg1 1 0.27 1.21 0.03
91 INT237344 Negative_regulation of Phosphorylation of Lipg 3 0.14 0.49 0
92 INT237349 Phosphorylation of Lipg 2 0.26 0.82 0
93 INT102264 Positive_regulation of Gene_expression of Lipg 2 0.35 0.3 0
94 INT197740 Localization of CETP 2 0.53 2.42 0
95 INT326077 Positive_regulation of Transcription of ABCA1 1 0.41 0.22 0
96 INT326076 Phosphorylation of ABCA1 1 0.73 0.66 0
97 INT281264 Positive_regulation of Negative_regulation of Lipg 1 0.07 0.5 0
98 INT326868 Positive_regulation of Transcription of HNF4A 1 0.04 0.08 0
99 INT292412 Negative_regulation of Positive_regulation of Lipg 1 0.05 0.07 0
100 INT326083 Positive_regulation of Phosphorylation of ABCA1 1 0.61 0.66 0
101 INT63321 Positive_regulation of Binding of Lipg 1 0.02 0 0
102 INT179190 Negative_regulation of Positive_regulation of Lipg 1 0.51 0.62 0
103 INT312771 Negative_regulation of Positive_regulation of CETP 1 0.13 1.76 0
104 INT326878 Negative_regulation of Gene_expression of HNF4A 1 0.03 0.43 0
105 INT312772 Regulation of Gene_expression of CETP 1 0.12 0.88 0
106 INT287915 Positive_regulation of Positive_regulation of HNF4A 1 0.06 0.37 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox