GO:0060585

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Latest revision as of 15:15, 22 January 2013

Name positive regulation of prostaglandin-endoperoxide synthase activity
Categary Process
Go Slim No
Go Link GO:0060585
Unique Molecular Interactions 274
Total Molecular Interactions 389
Total Single Events 2771
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

[edit] Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of prostaglandin-endoperoxide synthase activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of prostaglandin-endoperoxide synthase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
2 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
3 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
4 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
5 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
6 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
7 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
8 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
9 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
10 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
11 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
12 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
13 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
14 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
15 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
16 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
17 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
18 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
19 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
20 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
21 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
22 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
23 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
24 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
25 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
26 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
27 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
28 INT94020 Binding of EDN2 and INSRR 1 0.03 0 0.65
29 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
30 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
31 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
32 INT131642 Edn1 Positive_regulation of Positive_regulation of Insrr 1 0.01 0.44 0.6
33 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
34 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
35 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
36 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
37 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
38 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
39 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
40 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
41 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
42 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
43 INT94018 Binding of EDN2 and EDN3 1 0.19 0 0.48
44 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
45 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
46 INT50497 Edn1 Positive_regulation of Pla2g1b 1 0.01 0.23 0.45
47 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
48 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
49 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
50 INT153766 Edn1 Positive_regulation of Gtf3a 1 0.04 1.25 0.41
51 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
52 INT99399 Penk Positive_regulation of Edn1 1 0.00 0 0.38
53 INT99400 Gast Positive_regulation of Edn1 1 0.00 0 0.38
54 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37
55 INT313701 Calca Negative_regulation of Binding of Edn1 1 0.30 0.14 0.37
56 INT152314 Il18 Regulation of Edn1 1 0.02 0.22 0.36
57 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
58 INT152316 Ifng Regulation of Edn1 1 0.01 0.22 0.35
59 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
60 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
61 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33
62 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
63 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32
64 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
65 INT182262 EDN1 Positive_regulation of Gene_expression of NOS2 1 0.28 0.79 0.31
66 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31
67 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
68 INT54639 Edn3 Negative_regulation of Edn2 1 0.00 0 0.28
69 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26
70 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
71 INT178095 EDN1 Positive_regulation of MMP3 1 0.04 0.88 0.24
72 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
73 INT178085 EDN1 Positive_regulation of MMP7 1 0.06 0.89 0.24
74 INT178141 EDN1 Positive_regulation of Timp1 1 0.30 0.89 0.24
75 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
76 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24
77 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
78 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 0.28 0.89 0.24
79 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
80 INT290378 NOD2 Negative_regulation of TLR2 1 0.27 0.83 0.23
81 INT290377 NOD2 Negative_regulation of Positive_regulation of TLR2 1 0.24 0.95 0.23
82 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
83 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22
84 INT182265 EDN1 Positive_regulation of NOS2 1 0.24 0.56 0.22
85 INT182263 EDN1 Positive_regulation of MMP1 1 0.15 0.43 0.21
86 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
87 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
88 INT182258 EDN1 Positive_regulation of Positive_regulation of MMP1 1 0.15 0.47 0.19
89 INT182271 EDN1 Positive_regulation of Localization of MMP13 1 0.27 0.47 0.19
90 INT219915 Edn1 Regulation of Positive_regulation of Trpv1 1 0.33 0 0.18
91 INT140096 Gtf3a Positive_regulation of Gene_expression of Edn1 1 0.02 0.44 0.18
92 INT171386 Edn1 Positive_regulation of Mapk1 1 0.05 0.13 0.18
93 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
94 INT284450 Edn1 Positive_regulation of Gene_expression of MMP9 1 0.01 0.3 0.18
95 INT140094 Ifng Regulation of Gene_expression of Edn1 1 0.18 0.44 0.18
96 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
97 INT203759 Binding of EDN1 and TNF 1 0.16 0.71 0.16
98 INT324899 Edn1 Positive_regulation of Positive_regulation of Mmp9 1 0.10 0.66 0.16
99 INT94022 Positive_regulation of Binding of EDN1 and INSRR 1 0.06 0 0.16
100 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16
101 INT94021 Binding of EDN1 and EDN2 1 0.26 0 0.16
102 INT204791 Binding of Spg7 and Nod2 1 0.03 0.5 0.16
103 INT94013 Positive_regulation of Binding of EDN2 and INSRR 1 0.04 0 0.16
104 INT94014 Positive_regulation of Binding of EDN1 and EDN3 1 0.36 0 0.16
105 INT94023 Positive_regulation of Binding of EDN2 and EDN3 1 0.25 0 0.16
106 INT204789 Binding of Tlr2 and Nod2 1 0.23 0.44 0.16
107 INT324894 Edn1 Positive_regulation of Gene_expression of Mmp3 1 0.07 0.66 0.16
108 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15
109 INT21509 Agt Regulation of Edn1 1 0.53 0 0.15
110 INT182261 EDN1 Regulation of Gene_expression of MMP1 1 0.17 0.7 0.15
111 INT318305 Binding of NOD2 and NLRP3 1 0.08 1.76 0.15
112 INT50500 Edn1 Positive_regulation of PTGS1 1 0.00 0.07 0.14
113 INT324898 Ece1 Regulation of Gene_expression of Edn1 1 0.17 0.8 0.14
114 INT161799 Positive_regulation of Binding of ECE1 and EDN1 1 0.07 0.68 0.14
115 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14
116 INT161798 Positive_regulation of Binding of EDN1 and ING1 1 0.06 0.66 0.13
117 INT161800 Binding of EDN1 and ING1 1 0.05 0.65 0.13
118 INT145830 Mdp1 Positive_regulation of Nod2 1 0.34 0.52 0.13
119 INT178083 EDN1 Positive_regulation of Gene_expression of VEGFA 1 0.09 1.8 0.13
120 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12
121 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
122 INT77863 EDN1 Positive_regulation of POMC 1 0.50 0.34 0.12
123 INT182273 EDN1 Regulation of Gene_expression of BAD 1 0.11 0.73 0.12
124 INT180445 Edn1 Positive_regulation of Rhoa 1 0.08 0.57 0.11
125 INT182270 EDN1 Positive_regulation of Gene_expression of MMP1 1 0.18 0.55 0.1
126 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1
127 INT181570 Binding of Edn1 and Mapk1 1 0.13 2.72 0.1
128 INT6674 Edn1 Positive_regulation of Gene_expression of FOS 1 0.08 0.19 0.1
129 INT139476 Edn1 Positive_regulation of Ednra 1 0.00 1.07 0.1
130 INT10904 Edn1 Regulation of Localization of Nppb 1 0.22 0.54 0.1
131 INT92956 Edn1 Regulation of Positive_regulation of Nos2 1 0.18 0.17 0.09
132 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09
133 INT230750 Crp Positive_regulation of Edn1 1 0.10 0.27 0.09
134 INT92957 Edn1 Regulation of Gene_expression of Nos2 1 0.18 0.17 0.09
135 INT242257 Binding of EDN1 and ELF3 1 0.17 0.21 0.08
136 INT181584 Binding of EDNRB and Edn1 1 0.46 0.85 0.08
137 INT181583 Binding of Edn1 and Positive_regulation of NOS1 1 0.02 0.86 0.08
138 INT178100 Gene_expression of EDNRB Positive_regulation of EDN1 1 0.17 1.11 0.08
139 INT113369 Edn1 Regulation of Adarb1 1 0.02 0.14 0.08
140 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 0.04 1.18 0.08
141 INT178080 EDN1 Positive_regulation of HIF1A 1 0.05 1.05 0.08
142 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07
143 INT182269 EDN1 Positive_regulation of Localization of MMP1 1 0.17 0.31 0.07
144 INT192908 Edn1 Positive_regulation of Ednra 1 0.21 0.35 0.07
145 INT242258 ELF3 Negative_regulation of EDN1 1 0.15 0.09 0.07
146 INT309941 Edn1 Positive_regulation of Tlr2 1 0.02 1.31 0.07
147 INT172382 AGT Positive_regulation of Localization of EDN1 1 0.03 0.34 0.07
148 INT182268 Negative_regulation of MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
149 INT192907 Edn1 Positive_regulation of Ednrb 1 0.10 0.35 0.07
150 INT182274 MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
151 INT191219 Edn1 Positive_regulation of Amigo2 1 0.06 1.26 0.07
152 INT324896 Ece1 Positive_regulation of Negative_regulation of Edn1 1 0.19 0.42 0.07
153 INT172381 AVP Positive_regulation of Localization of EDN1 1 0.01 0.34 0.07
154 INT178096 EDN1 Positive_regulation of Gene_expression of EDNRB 1 0.17 1.01 0.07
155 INT181645 Edn1 Positive_regulation of NOS3 1 0.02 0.21 0.07
156 INT178090 EDN1 Positive_regulation of Phosphorylation of GJA1 1 0.09 0.88 0.06
157 INT191216 Binding of Edn1 and Cotl1 1 0.14 0.63 0.05
158 INT182259 EDN1 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.27 0.05
159 INT180668 Edn1 Positive_regulation of Gene_expression of Col1a1 1 0.02 0 0.05
160 INT182264 EDN1 Positive_regulation of Positive_regulation of MAPK14 1 0.26 0.1 0.05
161 INT180667 Edn1 Regulation of Ecm1 1 0.04 0 0.05
162 INT213263 INS Positive_regulation of EDN1 1 0.12 0.54 0.04
163 INT178091 EDN1 Positive_regulation of Gene_expression of PTGER2 1 0.01 0.74 0.04
164 INT353314 Edn1 Positive_regulation of Kalrn 1 0.03 0.21 0.04
165 INT229371 Positive_regulation of Pparg Negative_regulation of Gene_expression of Edn1 1 0.01 0.92 0.04
166 INT178098 EDN1 Positive_regulation of Transcription of VEGFA 1 0.08 0.76 0.04
167 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04
168 INT306514 EDN1 Positive_regulation of EDNRB 1 0.11 0.98 0.04
169 INT353317 Edn1 Positive_regulation of RHOA 1 0.19 0.16 0.04
170 INT178082 EDN1 Positive_regulation of VEGFA 1 0.08 0.77 0.04
171 INT323623 Binding of Adm and Edn1 1 0.04 0.77 0.03
172 INT239229 Regulation of Binding of Edn1 and Ednra 1 0.01 0.37 0.03
173 INT321407 EDN1 Positive_regulation of Phosphorylation of IRS1 1 0.06 1.07 0.03
174 INT345298 NLRP3 Positive_regulation of Localization of Edn1 1 0.01 0.94 0.03
175 INT256228 EDNRB Positive_regulation of EDN1 1 0.26 0.62 0.03
176 INT239225 Binding of Edn1 and Ednrb 1 0.02 0.36 0.03
177 INT292081 Binding of EDN1 and NCOR2 1 0.00 0.98 0.03
178 INT239228 Regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03
179 INT239224 Positive_regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03
180 INT222259 EIF4E Regulation of Negative_regulation of NOD2 1 0.13 0.1 0
181 INT213030 Hdl1 Regulation of Gene_expression of Edn1 1 0.06 0.88 0
182 INT10901 Edn1 Positive_regulation of Localization of Nppb 1 0.39 0.68 0
183 INT6676 Binding of Edn1 and Regulation of Gene_expression of CREB1 1 0.04 0.15 0
184 INT10909 Edn1 Positive_regulation of Nppb 1 0.39 0.16 0
185 INT186689 Binding of ACHE and Edn1 1 0.28 0 0
186 INT186685 Edn1 Regulation of Gene_expression of Il6 1 0.11 1.1 0
187 INT284143 EDN1 Positive_regulation of CA2 1 0.03 0.37 0
188 INT192910 Edn1 Regulation of Col4a1 1 0.16 0.49 0
189 INT10902 Edn1 Regulation of Avp 1 0.27 0.35 0
190 INT182267 EDN1 Regulation of Gene_expression of NOS2 1 0.36 0 0
191 INT111394 Binding of Edn1 and Pscs 1 0.25 0 0
192 INT191220 Cotl1 Positive_regulation of Edn1 1 0.19 0.69 0
193 INT191218 Edn1 Regulation of Positive_regulation of Prkcg 1 0.14 0.32 0
194 INT280620 Fig4 Regulation of Gene_expression of Edn1 1 0.03 0 0
195 INT356497 CGA Regulation of Edn1 1 0.02 0 0
196 INT6662 Edn1 Positive_regulation of Positive_regulation of Fos 1 0.00 0.17 0
197 INT182257 EDN1 Positive_regulation of Phosphorylation of AKT1 1 0.21 0.05 0
198 INT192911 Edn1 Positive_regulation of Positive_regulation of Col4a1 1 0.24 0.13 0
199 INT10905 Edn1 Regulation of Agt 1 0.11 0.35 0
200 INT230723 ERVW-1 Positive_regulation of Gene_expression of EDN1 1 0.00 1.95 0

[edit] Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of prostaglandin-endoperoxide synthase activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of prostaglandin-endoperoxide synthase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
2 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
3 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
4 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
5 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
6 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
7 INT5048 Binding of Edn1 55 0.47 18.86 19.16
8 INT9191 Localization of EDN1 94 0.81 57.01 14.78
9 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
10 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
11 INT6365 Localization of Edn1 56 0.81 18.84 13.83
12 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
13 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
14 INT6361 Localization of Edn1 30 0.81 19.09 9.7
15 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
16 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
17 INT10237 Binding of EDN1 40 0.48 16 8.48
18 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
19 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
20 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
21 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
22 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
23 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
24 INT53374 Binding of Edn1 17 0.43 11.66 2.98
25 INT103910 Binding of NOD2 19 0.47 12.24 2.93
26 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
27 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
28 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
29 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
30 INT76834 Negative_regulation of Gene_expression of Edn1 4 0.43 1.76 1.88
31 INT117221 Positive_regulation of Gene_expression of NOD2 7 0.65 4.39 1.83
32 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
33 INT162793 Regulation of NOD2 6 0.45 7.61 1.78
34 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
35 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
36 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
37 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
38 INT15407 Positive_regulation of Positive_regulation of Edn1 5 0.62 3.69 1.49
39 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
40 INT65640 Positive_regulation of Localization of Edn1 2 0.42 2.16 1.48
41 INT117219 Positive_regulation of NOD2 9 0.69 4.66 1.31
42 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
43 INT17802 Transcription of Edn1 6 0.24 6.31 1.18
44 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
45 INT61123 Localization of Edn2 1 0.55 0.27 1.05
46 INT154227 Regulation of Gene_expression of NOD2 3 0.44 3.38 0.99
47 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
48 INT49255 Protein_catabolism of EDN1 5 0.99 2.66 0.95
49 INT69422 Positive_regulation of Negative_regulation of EDN1 2 0.43 0.96 0.95
50 INT49254 Transcription of EDN1 5 0.69 2.42 0.94
51 INT152081 Phosphorylation of Edn1 1 0.53 0.39 0.9
52 INT61591 Negative_regulation of Localization of EDN1 11 0.59 2.09 0.85
53 INT57433 Positive_regulation of Binding of EDN1 3 0.49 0.62 0.82
54 INT186681 Gene_expression of Edn2 2 0.09 1.01 0.76
55 INT61121 Regulation of Regulation of Edn1 1 0.43 0.2 0.75
56 INT8614 Negative_regulation of Edn2 3 0.06 0.07 0.73
57 INT59970 Positive_regulation of Binding of Edn1 2 0.40 1.11 0.71
58 INT21957 Negative_regulation of Negative_regulation of Edn1 5 0.43 1.34 0.69
59 INT49252 Positive_regulation of Localization of EDN1 17 0.69 6.55 0.66
60 INT100396 Transcription of Edn1 7 0.69 2.48 0.66
61 INT49256 Regulation of Positive_regulation of EDN1 2 0.45 2.5 0.65
62 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57
63 INT135715 Negative_regulation of Localization of Edn1 5 0.42 1.7 0.56
64 INT63910 Regulation of Positive_regulation of Edn1 2 0.43 0.64 0.54
65 INT131641 Negative_regulation of Negative_regulation of Edn1 1 0.37 0.31 0.52
66 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51
67 INT8663 Positive_regulation of EDN2 3 0.38 0.65 0.5
68 INT204781 Positive_regulation of Nod2 6 0.45 2.79 0.46
69 INT55372 Regulation of Localization of Edn1 2 0.38 0.64 0.46
70 INT57434 Regulation of Regulation of EDN1 1 0.40 0.47 0.44
71 INT222266 Transcription of NOD2 5 0.68 0.76 0.43
72 INT81433 Negative_regulation of Positive_regulation of Edn1 4 0.39 0.81 0.38
73 INT171764 Localization of NOD2 2 0.74 0.86 0.37
74 INT113368 Regulation of Negative_regulation of Edn1 1 0.45 0.71 0.35
75 INT141013 Regulation of Gene_expression of Edn1 2 0.24 0.55 0.34
76 INT183240 Negative_regulation of NOD2 6 0.43 1.52 0.33
77 INT16368 Protein_catabolism of Edn1 2 0.72 0.18 0.31
78 INT244148 Positive_regulation of Positive_regulation of NOD2 1 0.47 0.68 0.31
79 INT222270 Regulation of Localization of NOD2 1 0.45 0.63 0.28
80 INT346895 Positive_regulation of Gene_expression of Nod2 1 0.33 0.74 0.28
81 INT84038 Protein_catabolism of Edn1 2 0.86 0.69 0.26
82 INT346896 Binding of Nod2 1 0.21 0.72 0.26
83 INT8660 Positive_regulation of Positive_regulation of EDN2 2 0.38 0.23 0.22
84 INT346899 Regulation of Positive_regulation of Nod2 1 0.18 0.75 0.22
85 INT67265 Positive_regulation of Negative_regulation of Edn1 1 0.61 0.05 0.21
86 INT156920 Phosphorylation of EDN1 4 0.61 0.66 0.19
87 INT53372 Positive_regulation of Regulation of Edn1 1 0.50 0 0.19
88 INT100397 Regulation of Transcription of Edn1 1 0.00 0.1 0.19
89 INT26353 Binding of Edn2 1 0.01 0 0.17
90 INT323040 Gene_expression of EDN2 1 0.32 0.13 0.13
91 INT222274 Regulation of Regulation of NOD2 1 0.27 0.45 0.13
92 INT284152 Regulation of Transcription of EDN1 1 0.32 0.44 0.13
93 INT6362 Negative_regulation of Localization of Edn1 3 0.16 1.92 0.12
94 INT15391 Negative_regulation of Positive_regulation of Edn1 2 0.07 0.1 0.1
95 INT170744 Positive_regulation of Transcription of Edn1 2 0.20 1.3 0.1
96 INT323038 Regulation of Positive_regulation of EDN2 1 0.21 0 0.1
97 INT204777 Negative_regulation of Localization of Nod2 1 0.28 0.61 0.09
98 INT49257 Positive_regulation of Transcription of EDN1 2 0.46 1.1 0.08
99 INT126441 Negative_regulation of Transcription of Edn1 1 0.40 0.17 0.08
100 INT204779 Localization of Nod2 1 0.48 0.6 0.08
101 INT204770 Regulation of Nod2 1 0.29 0.66 0.07
102 INT222267 Regulation of Transcription of NOD2 1 0.45 0 0.05
103 INT346893 Negative_regulation of Gene_expression of Nod2 1 0.28 0.13 0.04
104 INT323037 Negative_regulation of EDN2 1 0.20 0.23 0
105 INT284053 Positive_regulation of Positive_regulation of Nod2 1 0.25 0.08 0
106 INT280682 Positive_regulation of Transcription of Edn1 1 0.34 0 0
107 INT49261 Negative_regulation of Protein_catabolism of EDN1 1 0.58 0 0
108 INT323036 Regulation of EDN2 1 0.13 0 0
109 INT323041 Binding of EDN2 1 0.18 0.12 0
110 INT222273 Positive_regulation of Regulation of NOD2 1 0.46 0.09 0
111 INT323039 Regulation of Binding of EDN2 1 0.21 0.12 0
112 INT181578 Negative_regulation of Phosphorylation of Edn1 1 0.37 0.1 0
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