GO:0060712

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Name spongiotrophoblast layer development
Categary Process
Go Slim No
Go Link GO:0060712
Unique Molecular Interactions 58
Total Molecular Interactions 71
Total Single Events 361
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for spongiotrophoblast layer development. They are ordered first by their pain relevance and then by number of times they were reported for spongiotrophoblast layer development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
2 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78
3 INT190211 Adm Regulation of MMP12 1 0.29 0 0.65
4 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
5 INT108441 Adm Positive_regulation of Sst 1 0.40 0 0.54
6 INT346146 ADM Positive_regulation of Gene_expression of PERP 1 0.02 1.54 0.51
7 INT141964 Binding of ADM and RAMP1 1 0.30 2.63 0.47
8 INT108440 Adm Regulation of Localization of Sst 1 0.41 0 0.45
9 INT48038 Adm Regulation of Calca 1 0.31 0.14 0.42
10 INT346151 Binding of ADM and GPER 1 0.01 0.99 0.41
11 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
12 INT346150 Binding of ADM and FN1 1 0.10 0.93 0.39
13 INT346140 Positive_regulation of Binding of ADM and MMRN1 1 0.04 0.93 0.39
14 INT346139 Binding of ADM and MMRN1 1 0.03 0.93 0.39
15 INT346135 Positive_regulation of Binding of ADM and FN1 1 0.13 0.93 0.39
16 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
17 INT346145 Binding of ADM and TPX2 1 0.01 1.05 0.35
18 INT78780 Binding of Calca and Adm 1 0.32 0.07 0.26
19 INT78781 Binding of Adm and Calca 1 0.01 0.07 0.26
20 INT85011 ADM Regulation of CALCRL 1 0.06 0 0.24
21 INT346134 ADM Regulation of Gene_expression of MMRN1 1 0.04 1.29 0.23
22 INT78782 Binding of Adm and Adm 1 0.01 0.07 0.23
23 INT346143 ADM Regulation of Gene_expression of TPX2 1 0.02 1.29 0.23
24 INT172254 Binding of ADM and TAS2R14 1 0.02 0 0.17
25 INT172245 Binding of ADM and NCOR2 1 0.01 0 0.15
26 INT172236 Binding of ADM and APLNR 1 0.06 0 0.14
27 INT105913 Adm Negative_regulation of Adm 1 0.01 0 0.14
28 INT72029 Binding of ADM and IAPP 1 0.12 0.26 0.13
29 INT206856 Binding of Adm and Calcrl 1 0.04 1.76 0.1
30 INT179343 Adm Positive_regulation of Pscs 1 0.33 0.51 0.1
31 INT346136 ADM Positive_regulation of ICAM1 1 0.20 0.92 0.08
32 INT100127 ADM Positive_regulation of PRL 1 0.28 0.51 0.08
33 INT346147 ADM Positive_regulation of Gene_expression of VCAM1 1 0.19 0.91 0.08
34 INT346149 ADM Positive_regulation of Gene_expression of SELE 1 0.22 0.85 0.07
35 INT116388 Binding of Adm and Cpox 1 0.14 0.2 0.05
36 INT206897 Binding of HTR1A and Adm 1 0.02 0.87 0.05
37 INT207700 ADM Regulation of MSMB 1 0.18 0.69 0.04
38 INT323623 Binding of Adm and Edn1 1 0.04 0.77 0.03
39 INT261036 Adm Regulation of Gmcl1 1 0.04 0.4 0
40 INT225085 Binding of ADM and Negative_regulation of LEP 1 0.16 1.04 0
41 INT261034 Adm Positive_regulation of Gmcl1 1 0.03 0.4 0
42 INT303004 Adm Positive_regulation of Gsk3b 1 0.04 0.97 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for spongiotrophoblast layer development. They are ordered first by their pain relevance and then by number of times they were reported in spongiotrophoblast layer development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
2 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13
3 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92
4 INT70756 Gene_expression of Adm 28 0.77 13.33 4.22
5 INT76875 Positive_regulation of Adm 12 0.58 3.36 2.72
6 INT250727 Negative_regulation of ADM 3 0.38 8.32 2.26
7 INT141968 Positive_regulation of ADM 12 0.65 11.19 2
8 INT102449 Binding of ADM 12 0.33 5.85 1.73
9 INT118988 Negative_regulation of Adm 3 0.10 1.05 1.41
10 INT102228 Localization of Adm 9 0.69 1.58 1.34
11 INT169743 Regulation of Positive_regulation of Adm 1 0.37 0.38 1.32
12 INT252389 Negative_regulation of Gene_expression of ADM 2 0.38 4.78 1.3
13 INT48037 Regulation of Adm 8 0.44 3.96 1.24
14 INT141969 Positive_regulation of Gene_expression of ADM 4 0.57 4.07 1.2
15 INT81757 Regulation of Gene_expression of Adm 6 0.44 2.86 1.16
16 INT150838 Positive_regulation of Gene_expression of Adm 4 0.06 1.98 1.11
17 INT108347 Regulation of Adm 5 0.26 2.55 1.04
18 INT225094 Localization of ADM 5 0.63 3.89 0.91
19 INT118987 Localization of Adm 4 0.50 0.34 0.84
20 INT116247 Positive_regulation of Localization of Adm 1 0.04 0.17 0.62
21 INT74101 Negative_regulation of Adm 3 0.06 1.2 0.53
22 INT346181 Regulation of Gene_expression of ADM 1 0.35 1.67 0.52
23 INT116387 Binding of Adm 6 0.47 1 0.46
24 INT71561 Positive_regulation of Gene_expression of Adm 4 0.61 2.67 0.43
25 INT207726 Regulation of ADM 4 0.40 2.14 0.42
26 INT346173 Negative_regulation of Positive_regulation of ADM 1 0.38 1.02 0.39
27 INT150839 Regulation of Gene_expression of Adm 1 0.04 0.89 0.35
28 INT102450 Positive_regulation of Binding of ADM 1 0.29 0 0.24
29 INT122601 Transcription of Adm 1 0.29 0.73 0.24
30 INT122603 Positive_regulation of Transcription of Adm 1 0.26 0.74 0.24
31 INT150837 Positive_regulation of Regulation of Adm 1 0.06 0.64 0.23
32 INT102227 Protein_catabolism of Adm 1 0.30 0 0.21
33 INT102229 Regulation of Localization of Adm 1 0.08 0 0.13
34 INT261031 Positive_regulation of Positive_regulation of Adm 1 0.05 1.14 0.07
35 INT112599 Regulation of Positive_regulation of Adm 1 0.22 0 0.06
36 INT252388 Transcription of ADM 1 0.03 0 0.04
37 INT323621 Binding of Adm 1 0.32 1.02 0.03
38 INT225092 Positive_regulation of Localization of ADM 1 0.29 0.06 0
39 INT303019 Negative_regulation of Gene_expression of Adm 1 0.28 1.09 0
40 INT151209 Transcription of Adm 1 0.26 0.17 0
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