GO:0070141

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Name response to UV-A
Categary Process
Go Slim No
Go Link GO:0070141
Unique Molecular Interactions 791
Total Molecular Interactions 1126
Total Single Events 8536
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to UV-A. They are ordered first by their pain relevance and then by number of times they were reported for response to UV-A. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
3 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
4 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
5 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
6 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
7 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
8 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
9 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
10 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
11 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
12 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
13 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
14 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
15 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
16 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
17 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
18 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
19 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
20 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
21 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
22 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
23 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
24 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
25 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
26 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
27 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
28 INT169469 Binding of Egfr and Tgfa 1 0.19 1.87 0.91
29 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
30 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
31 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
32 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
33 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
34 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
35 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
36 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
37 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
38 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
39 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
40 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
41 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
42 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
43 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
44 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
45 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
46 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
47 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
48 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
49 INT169213 Binding of EGFR and CARTPT 1 0.00 0.22 0.67
50 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
51 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
52 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
53 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
54 INT169293 PTPLA Positive_regulation of AKT1 1 0.10 0.15 0.64
55 INT112870 Aap Positive_regulation of Gene_expression of Ccnd1 1 0.24 0.34 0.63
56 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
57 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
58 INT278695 MTX1 Negative_regulation of Phosphorylation of AKT1 1 0.04 0.81 0.62
59 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
60 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
61 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
62 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
63 INT169286 CNR1 Positive_regulation of Phosphorylation of EGFR 1 0.45 0.18 0.57
64 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
65 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
66 INT201944 CXCL10 Positive_regulation of Phosphorylation of AKT1 1 0.09 0.79 0.55
67 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
68 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
69 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
70 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
71 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
72 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
73 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
74 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
75 INT97952 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1 1 0.03 0.72 0.51
76 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
77 INT97951 ST3GAL3 Positive_regulation of AKT1 1 0.04 0.7 0.5
78 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
79 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49
80 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
81 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
82 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
83 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
84 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 0.14 1.01 0.47
85 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
86 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
87 INT162929 NQO1 Negative_regulation of Phosphorylation of AKT1 1 0.41 1 0.46
88 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
89 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
90 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
91 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
92 INT160048 INPPL1 Regulation of Gene_expression of AKT1 1 0.28 0.6 0.42
93 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
94 INT121851 AKT1 Regulation of ROS1 1 0.16 0.52 0.41
95 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
96 INT121848 AKT1 Regulation of CASP8 1 0.18 0.52 0.41
97 INT121854 AKT1 Regulation of BID 1 0.17 0.52 0.41
98 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
99 INT108197 AKT1 Regulation of JUN 1 0.29 0.25 0.4
100 INT231842 Pcdh8 Positive_regulation of Akt1 1 0.00 1.59 0.4
101 INT121853 Gene_expression of ROS1 Negative_regulation of AKT1 1 0.25 0.49 0.4
102 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
103 INT166155 Ccr9 Positive_regulation of Akt1 1 0.58 2.14 0.39
104 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
105 INT272751 EGFR Regulation of Negative_regulation of Prkca 1 0.01 0 0.38
106 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
107 INT89386 INS Positive_regulation of Phosphorylation of AKT1 3 0.43 1.48 0.36
108 INT299288 AKT1 Positive_regulation of RPTOR 1 0.34 0.05 0.36
109 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
110 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
111 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
112 INT176135 AKT1 Regulation of Localization of CYCS 1 0.43 2.16 0.35
113 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
114 INT309118 Dlat Positive_regulation of Positive_regulation of Akt1 1 0.03 0.32 0.34
115 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34
116 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34
117 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
118 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33
119 INT324525 PGE Positive_regulation of Positive_regulation of Egfr 1 0.41 1.05 0.33
120 INT324522 PGE Positive_regulation of Phosphorylation of Egfr 1 0.56 1.04 0.33
121 INT324524 PGE Positive_regulation of Egfr 1 0.38 1.05 0.33
122 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
123 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
124 INT337410 AKT3 Negative_regulation of AKT1 1 0.09 0.49 0.32
125 INT337414 AKT2 Negative_regulation of AKT1 1 0.10 0.5 0.32
126 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
127 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31
128 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
129 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
130 INT299307 AKT1 Positive_regulation of Positive_regulation of AKT1S1 1 0.10 0 0.3
131 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 0.17 0 0.3
132 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29
133 INT185799 Binding of EGFR and SPP1 1 0.19 0.64 0.29
134 INT291202 Positive_regulation of INS Positive_regulation of AKT1 1 0.01 0.76 0.29
135 INT166093 Negative_regulation of ROS1 Negative_regulation of Positive_regulation of EGFR 1 0.12 0.33 0.28
136 INT132367 Lgals1 Positive_regulation of Akt1 1 0.22 0.13 0.28
137 INT317533 Akt1 Positive_regulation of Nos1 1 0.43 0 0.28
138 INT166094 Negative_regulation of CSK Negative_regulation of Positive_regulation of EGFR 1 0.02 0.33 0.28
139 INT149322 Amph Positive_regulation of Akt1 1 0.39 0 0.27
140 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26
141 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26
142 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26
143 INT303082 Akt1 Negative_regulation of Gene_expression of Mafk 1 0.20 0.37 0.26
144 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25
145 INT314047 THL Negative_regulation of Phosphorylation of Akt1 1 0.14 0.71 0.25
146 INT258521 EGFR Positive_regulation of MMP2 1 0.39 0.91 0.24
147 INT326094 Akt1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.49 0.24
148 INT326092 Gene_expression of Akt1 Negative_regulation of Gopc 1 0.03 0.55 0.24
149 INT326093 Akt1 Positive_regulation of Gopc 1 0.03 0.43 0.23
150 INT258565 EGFR Positive_regulation of Meta 1 0.39 0.89 0.23
151 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23
152 INT272753 Positive_regulation of Prkaca Positive_regulation of EGFR 1 0.01 0 0.23
153 INT323173 THRA Positive_regulation of Phosphorylation of Akt1 1 0.00 0 0.22
154 INT260844 NRP2 Positive_regulation of Akt1 1 0.00 0.73 0.22
155 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
156 INT323174 DBT Positive_regulation of Phosphorylation of Akt1 1 0.01 0 0.21
157 INT120716 Binding of AKT1 and TEP1 1 0.05 0.46 0.21
158 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
159 INT289356 Binding of Akt1 and Fgf2 1 0.03 0.82 0.21
160 INT309661 C5 Positive_regulation of Phosphorylation of Akt1 1 0.51 0.45 0.21
161 INT221237 Prkca Regulation of Phosphorylation of Akt1 1 0.01 0.28 0.2
162 INT352355 Binding of CNR1 and EGFR 1 0.19 0.76 0.2
163 INT145152 Binding of EGF and EGFR 4 0.15 2.45 0.19
164 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
165 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18
166 INT303058 Akt1 Negative_regulation of Gene_expression of Syt1 1 0.21 0.43 0.18
167 INT221231 Pdpk1 Positive_regulation of Akt1 1 0.09 0.13 0.18
168 INT221244 Pdpk1 Positive_regulation of Phosphorylation of Akt1 1 0.09 0.13 0.18
169 INT298196 EGFR Positive_regulation of PIK3CD 1 0.04 0.65 0.18
170 INT298192 EGFR Positive_regulation of AKT1 1 0.10 0.65 0.18
171 INT121582 AKT1 Regulation of Gene_expression of GDF15 1 0.21 0.4 0.18
172 INT318324 Binding of AKT1 and PRKCA 1 0.03 0.63 0.18
173 INT253129 Ins1 Regulation of Phosphorylation of Akt1 3 0.11 1.66 0.17
174 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
175 INT179841 Il11 Regulation of Positive_regulation of Akt1 1 0.08 0.07 0.17
176 INT105334 PTGER1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.66 0.17
177 INT282858 Bpifa2 Negative_regulation of Akt1 1 0.05 0.91 0.17
178 INT176134 AKT1 Regulation of Gene_expression of BIRC3 1 0.08 1.09 0.17
179 INT226209 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.10 1.16 0.17
180 INT282861 Bpifa2 Negative_regulation of Phosphorylation of Akt1 1 0.05 0.91 0.17
181 INT352354 EGFR Regulation of Gene_expression of CNR1 1 0.23 1.16 0.17
182 INT327310 Binding of Ccnd1 and Elavl1 1 0.04 0.38 0.16
183 INT218937 Akt1 Positive_regulation of Parn 1 0.01 0.65 0.16
184 INT316484 Akt1 Positive_regulation of Positive_regulation of Stat3 1 0.01 0.87 0.16
185 INT343475 Epo Regulation of Akt1 1 0.18 0.41 0.16
186 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16
187 INT343478 Epo Regulation of Gene_expression of Akt1 1 0.40 0.41 0.16
188 INT112132 Gast Positive_regulation of Positive_regulation of Egfr 1 0.33 0.13 0.16
189 INT218930 Akt1 Positive_regulation of Xiap 1 0.06 0.64 0.16
190 INT327325 Binding of Hnrnpd and Ccnd1 1 0.03 0.38 0.16
191 INT224697 TNF Positive_regulation of Akt1 1 0.01 0 0.15
192 INT293698 Positive_regulation of Binding of Akt1 and Plek 1 0.05 0.12 0.15
193 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
194 INT293695 Binding of Akt1 and Plek 1 0.03 0.12 0.15
195 INT292749 Akt1 Positive_regulation of Ctnnd2 1 0.09 1.73 0.15
196 INT231844 Pcdh8 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.63 0.15
197 INT224694 Il1 Positive_regulation of Akt1 1 0.01 0 0.15
198 INT293699 Regulation of Binding of Akt1 and Plek 1 0.04 0.12 0.15
199 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
200 INT213005 Hdl1 Positive_regulation of Akt1 3 0.19 3.81 0.14

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to UV-A. They are ordered first by their pain relevance and then by number of times they were reported in response to UV-A. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
2 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
3 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
4 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
5 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
6 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
7 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
8 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
9 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
10 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
11 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
12 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
13 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
14 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
15 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
16 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
17 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
18 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55
19 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
20 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
21 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
22 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
23 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59
24 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
25 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34
26 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33
27 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
28 INT11154 Binding of EGFR 149 0.48 96.23 6.29
29 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
30 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
31 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
32 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61
33 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93
34 INT105336 Regulation of AKT1 52 0.56 32.53 4.89
35 INT134657 Localization of Akt1 37 0.68 11.58 4.62
36 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
37 INT103914 Phosphorylation of Egfr 35 0.82 16.98 4.31
38 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21
39 INT75136 Binding of Akt1 27 0.27 8.81 4.15
40 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
41 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
42 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
43 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
44 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
45 INT136692 Localization of Akt1 12 0.78 2.14 3.65
46 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45
47 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
48 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
49 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19
50 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
51 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11
52 INT117348 Regulation of EGFR 75 0.61 47.73 3.09
53 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
54 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02
55 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8
56 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
57 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66
58 INT214355 Binding of Akt1 13 0.36 3.72 2.59
59 INT93396 Positive_regulation of Gene_expression of Ccnd1 13 0.52 8.59 2.26
60 INT118791 Binding of AKT1 32 0.48 15.51 2.25
61 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22
62 INT103917 Positive_regulation of Phosphorylation of Egfr 12 0.68 7.23 2.18
63 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14
64 INT93398 Negative_regulation of Gene_expression of Ccnd1 5 0.44 2.61 2.12
65 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08
66 INT65545 Localization of EGFR 35 0.79 20.8 1.88
67 INT112131 Positive_regulation of Positive_regulation of Egfr 10 0.49 9.95 1.85
68 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83
69 INT120563 Positive_regulation of Gene_expression of Egfr 56 0.70 46.19 1.82
70 INT112867 Positive_regulation of Gene_expression of Ccnd1 15 0.56 13.22 1.77
71 INT142236 Regulation of Phosphorylation of Akt1 13 0.61 5.02 1.75
72 INT124953 Negative_regulation of Gene_expression of Egfr 6 0.42 1.97 1.75
73 INT165332 Negative_regulation of Negative_regulation of Akt1 5 0.42 3.27 1.7
74 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
75 INT118292 Negative_regulation of Phosphorylation of EGFR 27 0.59 13.62 1.54
76 INT96993 Positive_regulation of Phosphorylation of EGFR 15 0.59 5.44 1.37
77 INT108327 Negative_regulation of Gene_expression of Ccnd1 18 0.38 14.36 1.31
78 INT127725 Negative_regulation of Positive_regulation of EGFR 6 0.57 2.69 1.3
79 INT167409 Regulation of Gene_expression of AKT1 8 0.56 4.86 1.23
80 INT135556 Localization of AKT1 38 0.69 12.78 1.17
81 INT128987 Negative_regulation of Ccnd1 24 0.52 15.78 1.15
82 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15
83 INT176147 Regulation of Phosphorylation of AKT1 14 0.41 6.41 1.13
84 INT207203 Transcription of Akt1 6 0.67 3.73 1.1
85 INT118293 Regulation of Phosphorylation of EGFR 2 0.61 1.01 1.1
86 INT144427 Transcription of Ccnd1 10 0.41 7.89 1.07
87 INT191050 Positive_regulation of Negative_regulation of Akt1 6 0.31 1.82 1.03
88 INT86384 Negative_regulation of Localization of EGFR 4 0.43 2.5 0.97
89 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96
90 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94
91 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
92 INT59198 Regulation of Ccnd1 11 0.47 6.54 0.9
93 INT163280 Negative_regulation of Phosphorylation of CCND1 6 0.19 3.92 0.87
94 INT109007 Positive_regulation of Ccnd1 23 0.53 9.5 0.86
95 INT144415 Regulation of Positive_regulation of Egfr 2 0.27 0.42 0.86
96 INT117347 Positive_regulation of Positive_regulation of EGFR 15 0.69 11.17 0.84
97 INT144416 Regulation of Egfr 5 0.57 4.97 0.83
98 INT171361 Regulation of Egfr 16 0.62 8.36 0.81
99 INT163289 Phosphorylation of CCND1 7 0.36 4.81 0.81
100 INT144414 Positive_regulation of Positive_regulation of Egfr 1 0.49 0.65 0.8
101 INT131286 Binding of Egfr 26 0.44 13.58 0.78
102 INT138955 Transcription of EGFR 18 0.71 11.39 0.78
103 INT186119 Protein_catabolism of EGFR 6 0.98 3.68 0.76
104 INT151170 Regulation of Regulation of Akt1 2 0.45 3.28 0.73
105 INT114246 Positive_regulation of Negative_regulation of EGFR 13 0.49 8.67 0.7
106 INT299338 Negative_regulation of Regulation of AKT1 2 0.31 2.32 0.68
107 INT186117 Negative_regulation of Protein_catabolism of EGFR 1 0.42 0.67 0.68
108 INT186118 Positive_regulation of Protein_catabolism of EGFR 1 0.68 0.66 0.68
109 INT207204 Regulation of Transcription of Akt1 3 0.35 1.41 0.66
110 INT166024 Protein_catabolism of AKT1 5 0.46 2.6 0.64
111 INT144432 Positive_regulation of Transcription of Ccnd1 4 0.36 2.36 0.63
112 INT281466 Negative_regulation of Regulation of Akt1 1 0.33 0.31 0.63
113 INT128498 Regulation of CCND1 17 0.39 12.51 0.58
114 INT123131 Negative_regulation of Negative_regulation of AKT1 6 0.42 3.23 0.58
115 INT320644 Binding of Egfr 7 0.34 5.9 0.56
116 INT146802 Positive_regulation of Ccnd1 4 0.38 1.37 0.53
117 INT218900 Regulation of Negative_regulation of Akt1 3 0.15 1.73 0.53
118 INT75498 Positive_regulation of Gene_expression of CCND1 21 0.68 19.4 0.51
119 INT258835 Localization of Ccnd1 3 0.53 2.7 0.5
120 INT276189 Regulation of Localization of Akt1 1 0.43 0.2 0.5
121 INT146522 Negative_regulation of Positive_regulation of CCND1 3 0.30 2.04 0.48
122 INT103916 Negative_regulation of Phosphorylation of Egfr 12 0.59 7.03 0.47
123 INT196424 Binding of Ccnd1 5 0.29 3.34 0.47
124 INT93400 Negative_regulation of Ccnd1 4 0.33 0.77 0.47
125 INT142943 Phosphorylation of Egfr 5 0.81 1.56 0.45
126 INT142942 Positive_regulation of Phosphorylation of Egfr 4 0.68 1.52 0.45
127 INT158643 Negative_regulation of Negative_regulation of CCND1 2 0.31 2.43 0.45
128 INT169355 Localization of Egfr 6 0.75 3.24 0.43
129 INT185350 Negative_regulation of Gene_expression of Egfr 24 0.59 13.21 0.35
130 INT138954 Regulation of Transcription of EGFR 2 0.27 0.82 0.35
131 INT145155 Regulation of Positive_regulation of EGFR 6 0.38 4.54 0.33
132 INT186115 Negative_regulation of Negative_regulation of EGFR 5 0.57 3.42 0.33
133 INT321348 Positive_regulation of Localization of Akt1 1 0.30 0.08 0.32
134 INT186057 Binding of CCND1 8 0.31 5.92 0.26
135 INT239464 Regulation of Negative_regulation of Akt1 3 0.31 0.37 0.25
136 INT113989 Regulation of Gene_expression of CCND1 11 0.44 7.57 0.24
137 INT223597 Negative_regulation of Binding of EGFR 12 0.43 7.97 0.23
138 INT200666 Transcription of AKT1 8 0.66 4.23 0.2
139 INT230483 Protein_catabolism of Akt1 2 0.10 1.11 0.2
140 INT146801 Regulation of Ccnd1 5 0.34 2.4 0.19
141 INT276192 Transcription of Akt1 1 0.66 0.47 0.18
142 INT185352 Regulation of Gene_expression of Egfr 5 0.62 2.33 0.16
143 INT176153 Regulation of Negative_regulation of AKT1 3 0.39 2.13 0.16
144 INT171378 Negative_regulation of Binding of Egfr 3 0.43 1.48 0.16
145 INT171365 Negative_regulation of Regulation of Egfr 1 0.33 0.06 0.16
146 INT135557 Positive_regulation of Localization of AKT1 3 0.46 0.49 0.15
147 INT144682 Negative_regulation of Regulation of Egfr 1 0.43 0.41 0.15
148 INT226185 Protein_catabolism of Akt1 7 0.53 2.43 0.14
149 INT175416 Regulation of Negative_regulation of EGFR 4 0.60 3.94 0.14
150 INT302248 Negative_regulation of Binding of AKT1 2 0.25 1 0.14
151 INT299514 Localization of Egfr 2 0.37 0.38 0.14
152 INT145248 Negative_regulation of Negative_regulation of Ccnd1 1 0.23 0.47 0.13
153 INT285902 Positive_regulation of Transcription of AKT1 1 0.06 0.6 0.13
154 INT196428 Negative_regulation of Binding of Ccnd1 1 0.14 1.17 0.13
155 INT233419 Negative_regulation of Positive_regulation of Egfr 2 0.40 0.97 0.12
156 INT214360 Negative_regulation of Binding of Akt1 2 0.41 0.09 0.12
157 INT196427 Negative_regulation of Transcription of Ccnd1 1 0.14 1.17 0.12
158 INT355216 Positive_regulation of Binding of Akt1 1 0.37 0.35 0.12
159 INT169908 Localization of Ccnd1 7 0.57 2.68 0.11
160 INT199082 Positive_regulation of Binding of Akt1 4 0.17 1.25 0.11
161 INT184473 Regulation of Gene_expression of Ccnd1 5 0.40 2.73 0.1
162 INT219647 Negative_regulation of Negative_regulation of Egfr 1 0.19 0.13 0.1
163 INT215750 Transcription of Ccnd1 2 0.14 2.23 0.09
164 INT192239 Positive_regulation of Binding of AKT1 2 0.26 0.91 0.08
165 INT226648 Negative_regulation of Positive_regulation of Egfr 1 0.10 0 0.08
166 INT211211 Positive_regulation of Negative_regulation of Egfr 1 0.50 1.36 0.08
167 INT229184 Regulation of Protein_catabolism of EGFR 1 0.25 1.11 0.08
168 INT145375 Transcription of CCND1 7 0.52 3.86 0.07
169 INT266934 Regulation of Binding of EGFR 3 0.45 1.16 0.07
170 INT307475 Positive_regulation of Negative_regulation of Akt1 1 0.12 0.12 0.07
171 INT182302 Negative_regulation of Localization of AKT1 5 0.39 3.52 0.06
172 INT299512 Regulation of Localization of Egfr 1 0.13 0.11 0.06
173 INT215731 Positive_regulation of Transcription of Ccnd1 1 0.13 0.1 0.06
174 INT205021 Positive_regulation of Gene_expression of Egfr 3 0.64 4.15 0.05
175 INT279191 Regulation of Negative_regulation of Egfr 2 0.45 1.44 0.05
176 INT176590 Positive_regulation of Transcription of CCND1 1 0.17 0.27 0.05
177 INT183275 Positive_regulation of Regulation of EGFR 1 0.36 0.21 0.05
178 INT185349 Transcription of Egfr 8 0.72 4.01 0.04
179 INT185347 Negative_regulation of Transcription of Egfr 1 0.59 1.1 0.04
180 INT221830 Negative_regulation of Transcription of CCND1 3 0.18 2.15 0.03
181 INT300989 Positive_regulation of Negative_regulation of AKT1 2 0.41 1.27 0.03
182 INT225226 Positive_regulation of Negative_regulation of Ccnd1 1 0.14 1.18 0.03
183 INT258832 Regulation of Transcription of Ccnd1 1 0.16 1.57 0.03
184 INT145156 Regulation of Regulation of EGFR 1 0.24 1.31 0.03
185 INT288183 Positive_regulation of Regulation of Akt1 1 0.05 0.06 0.03
186 INT266931 Positive_regulation of Binding of EGFR 6 0.50 5.44 0
187 INT268244 Negative_regulation of Localization of Akt1 2 0.28 2 0
188 INT226657 Negative_regulation of Negative_regulation of Egfr 2 0.43 1.39 0
189 INT315831 Positive_regulation of Localization of EGFR 2 0.49 0.6 0
190 INT319331 Regulation of Localization of EGFR 2 0.32 1.85 0
191 INT215727 Regulation of Gene_expression of Ccnd1 2 0.12 0.49 0
192 INT225215 Negative_regulation of Positive_regulation of Ccnd1 2 0.13 1.33 0
193 INT236700 Phosphorylation of Ccnd1 2 0.18 1.89 0
194 INT225220 Positive_regulation of Positive_regulation of Ccnd1 1 0.14 1.2 0
195 INT305634 Localization of CCND1 1 0.07 2.69 0
196 INT231270 Positive_regulation of Localization of Egfr 1 0.15 0 0
197 INT293479 Positive_regulation of Protein_catabolism of Akt1 1 0.26 0.53 0
198 INT276362 Protein_catabolism of CCND1 1 0.10 0.66 0
199 INT226635 Negative_regulation of Protein_catabolism of Egfr 1 0.10 0.48 0
200 INT226703 Protein_catabolism of Egfr 1 0.22 0.61 0
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