GO:0070542

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Name response to fatty acid
Categary Process
Go Slim No
Go Link GO:0070542
Unique Molecular Interactions 626
Total Molecular Interactions 960
Total Single Events 4417
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to fatty acid. They are ordered first by their pain relevance and then by number of times they were reported for response to fatty acid. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
5 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
6 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
7 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
8 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
9 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
10 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
11 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
12 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
13 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
14 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
15 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
16 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
17 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
18 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
19 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
20 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
21 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
22 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
23 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
24 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
25 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
26 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
27 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
28 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
29 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
30 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
31 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
32 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
33 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
34 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
35 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
36 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
37 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
38 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89
39 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
40 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
41 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
42 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
43 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
44 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
45 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
46 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79
47 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
48 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
49 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
50 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
51 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
52 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
53 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
54 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
55 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
56 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
57 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
58 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
59 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
60 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
61 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64
62 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
63 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
64 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
65 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
66 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
67 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59
68 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
69 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
70 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
71 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
72 INT306330 Cd14 Positive_regulation of Gene_expression of Tlr4 1 0.48 0.54 0.57
73 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56
74 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
75 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
76 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
77 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56
78 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
79 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
80 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
81 INT310767 Tlr4 Regulation of Gene_expression of S100a8 1 0.02 0.7 0.54
82 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54
83 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
84 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52
85 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
86 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51
87 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51
88 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
89 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
90 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
91 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
92 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
93 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49
94 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49
95 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49
96 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
97 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48
98 INT322264 Binding of MPZ and TLR4 1 0.18 1.68 0.47
99 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
100 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47
101 INT284300 Tlr4 Positive_regulation of Gene_expression of Mir155 1 0.18 0.91 0.47
102 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46
103 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46
104 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46
105 INT310769 Pam Regulation of Tlr4 1 0.01 0.69 0.46
106 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
107 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43
108 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
109 INT308696 Binding of Tlr4 and Tlr4 1 0.00 0.34 0.42
110 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41
111 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
112 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
113 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39
114 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39
115 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
116 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
117 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
118 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39
119 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38
120 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38
121 INT204893 Regulation of Tlr4 Positive_regulation of gr 1 0.11 0.9 0.38
122 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
123 INT147969 Binding of Ly86 and Tlr4 1 0.30 0.37 0.38
124 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38
125 INT215275 Tlr4 Positive_regulation of Gene_expression of Ros1 1 0.01 1.37 0.38
126 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
127 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
128 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38
129 INT204905 Tlr4 Positive_regulation of gr 1 0.18 0.9 0.38
130 INT324821 Tlr4 Positive_regulation of Gene_expression of Maob 1 0.07 0.44 0.37
131 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
132 INT100091 Tlr4 Regulation of Localization of Tnf 1 0.01 0.42 0.37
133 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
134 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
135 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
136 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
137 INT110135 Tlr4 Regulation of Localization of Gnrh1 1 0.01 0.2 0.36
138 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
139 INT337304 PTAFR Positive_regulation of Gene_expression of TLR4 1 0.62 1.99 0.36
140 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36
141 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35
142 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
143 INT118743 Tlr4 Positive_regulation of Itgam 1 0.39 0.41 0.35
144 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
145 INT110132 Tlr4 Regulation of Localization of LH 1 0.01 0.2 0.35
146 INT310765 Binding of Pam and Tlr2 1 0.01 0.57 0.35
147 INT244324 Csf2 Positive_regulation of Tlr4 1 0.23 0.95 0.34
148 INT288200 Tlr2 Positive_regulation of Pik3r1 1 0.05 0.24 0.33
149 INT110134 Tlr4 Regulation of Regulation of Gnrh1 1 0.01 0.15 0.33
150 INT224691 Positive_regulation of Tlr4 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
151 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
152 INT224681 Tlr2 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
153 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32
154 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32
155 INT295198 Tlr4 Positive_regulation of Gene_expression of Ptger2 1 0.01 0.15 0.32
156 INT322016 Binding of IL1B and TLR4 1 0.05 0.18 0.32
157 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32
158 INT276604 Tlr4 Positive_regulation of Gene_expression of Paf 1 0.22 0.37 0.31
159 INT276605 Tlr4 Positive_regulation of Gene_expression of Mthfd1 1 0.06 0.37 0.31
160 INT249480 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Src 1 0.22 0.23 0.31
161 INT288198 Binding of Tlr4 and Mapk14 1 0.01 0.63 0.31
162 INT185319 Il6 Positive_regulation of Gene_expression of Tlr4 1 0.11 0.36 0.31
163 INT185322 TNF Positive_regulation of Gene_expression of Tlr4 1 0.01 0.36 0.31
164 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
165 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
166 INT306323 Tlr4 Positive_regulation of Ticam1 3 0.25 0.55 0.3
167 INT324832 Tlr4 Positive_regulation of IFNA1 1 0.05 0.46 0.3
168 INT229600 Tlr4 Positive_regulation of Il1a 1 0.00 0.41 0.3
169 INT223752 Tlr4 Positive_regulation of Il1 1 0.12 0.64 0.3
170 INT178342 Positive_regulation of Tlr4 Positive_regulation of Il6 1 0.13 0.25 0.3
171 INT306319 Cd14 Positive_regulation of Tlr4 1 0.48 0.29 0.3
172 INT168616 Tlr4 Negative_regulation of Localization of Tnf 1 0.33 0.44 0.3
173 INT163903 Binding of EFNB1 and Src 1 0.03 0.56 0.29
174 INT354368 FGFR1 Positive_regulation of Tlr4 1 0.01 0.16 0.29
175 INT144862 Tlr4 Positive_regulation of PGE 2 0.13 0.35 0.28
176 INT215274 Tlr4 Positive_regulation of Ros1 2 0.02 1.48 0.28
177 INT310696 Tlr4 Positive_regulation of Positive_regulation of Cftr 1 0.16 0.74 0.28
178 INT337293 PTAFR Positive_regulation of Positive_regulation of TLR4 1 0.62 1.43 0.28
179 INT339494 Eif2ak2 Positive_regulation of Tlr4 1 0.13 0.18 0.28
180 INT310255 Tlr4 Positive_regulation of Gene_expression of Cd86 2 0.18 0.06 0.27
181 INT276953 Positive_regulation of Tlr2 Positive_regulation of Phosphorylation of Stat3 1 0.38 0.93 0.27
182 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27
183 INT276979 Positive_regulation of Tlr2 Positive_regulation of Gene_expression of Stat3 1 0.38 0.93 0.27
184 INT295197 Tlr4 Positive_regulation of Ptger2 1 0.01 0.05 0.27
185 INT306018 Binding of Tlr4 and Tlr9 1 0.15 0.92 0.27
186 INT222428 Negative_regulation of Tlr4 Positive_regulation of Il6 1 0.01 0.26 0.27
187 INT222412 Cd14 Negative_regulation of Binding of Tlr4 1 0.02 0.26 0.27
188 INT222440 Tlr4 Positive_regulation of Localization of Pomc 1 0.01 0.35 0.27
189 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
190 INT268766 Tlr4 Positive_regulation of Gene_expression of Ccr1 1 0.04 0.4 0.26
191 INT78067 Tlr4 Positive_regulation of Localization of Ptger2 1 0.01 0.07 0.26
192 INT296794 Positive_regulation of Tlr2 Positive_regulation of Pik3r1 1 0.10 1.02 0.26
193 INT290707 Binding of Tlr4 and Cd200r1 1 0.01 0.7 0.26
194 INT222422 Tlr4 Positive_regulation of Il6 1 0.01 0.25 0.26
195 INT310766 Tlr4 Positive_regulation of Cxcl2 1 0.29 0.28 0.26
196 INT306325 Tlr4 Positive_regulation of Localization of Cd14 1 0.39 0.37 0.26
197 INT295200 Hspg2 Positive_regulation of Tlr4 1 0.00 0 0.25
198 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 0.23 0.2 0.25
199 INT323610 Tlr4 Positive_regulation of Hmgb1 1 0.25 0.2 0.25
200 INT350074 Binding of Tlr4 and Myadm 1 0.00 0.5 0.25

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to fatty acid. They are ordered first by their pain relevance and then by number of times they were reported in response to fatty acid. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
2 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
3 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
4 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
5 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
6 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
7 INT134651 Binding of TLR4 89 0.48 66.96 23.19
8 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
9 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
10 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
11 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
12 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
13 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
14 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
15 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
16 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
17 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
18 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
19 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
20 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
21 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
22 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
23 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
24 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
25 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67
26 INT97797 Localization of TLR4 18 0.77 13.78 6
27 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
28 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
29 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
30 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43
31 INT100222 Binding of Src 9 0.26 5.41 5.37
32 INT174688 Binding of Tlr2 45 0.42 36.65 5.25
33 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
34 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18
35 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
36 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
37 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
38 INT2213 Regulation of EP300 10 0.54 4.72 4.5
39 INT28734 Gene_expression of Reln 7 0.74 5.76 4.33
40 INT57642 Gene_expression of PCSK1 26 0.76 5.09 4.28
41 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
42 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
43 INT122327 Regulation of Src 6 0.59 0.59 3.6
44 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
45 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
46 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
47 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
48 INT156148 Gene_expression of CTGF 16 0.78 9.98 2.87
49 INT106286 Gene_expression of UCP2 15 0.77 7.24 2.78
50 INT140476 Regulation of FABP3 5 0.27 5.86 2.49
51 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47
52 INT140091 Gene_expression of Ctgf 26 0.78 14.21 2.39
53 INT29402 Gene_expression of Src 16 0.74 4.57 2.29
54 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
55 INT121543 Positive_regulation of Gene_expression of PCSK1 4 0.29 1.63 2.21
56 INT204775 Regulation of Tlr2 21 0.41 13.6 2.18
57 INT171514 Binding of EP300 13 0.32 4.32 2.01
58 INT136860 Positive_regulation of Fabp3 5 0.60 4.53 1.99
59 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
60 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
61 INT249530 Positive_regulation of Positive_regulation of Src 3 0.28 1.32 1.9
62 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
63 INT265064 Binding of Reln 1 0.02 2.7 1.83
64 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
65 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
66 INT89614 Positive_regulation of FABP3 12 0.50 10.16 1.75
67 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74
68 INT228195 Negative_regulation of Gene_expression of Tlr2 14 0.40 12.17 1.74
69 INT172622 Localization of EP300 8 0.65 2.56 1.72
70 INT265066 Positive_regulation of Reln 1 0.02 1.59 1.72
71 INT28735 Localization of Reln 2 0.12 1.49 1.7
72 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
73 INT112612 Gene_expression of Fabp3 14 0.59 6.35 1.47
74 INT174683 Transcription of Tlr2 12 0.58 5.95 1.4
75 INT159312 Regulation of Reln 4 0.43 1.79 1.4
76 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
77 INT221131 Localization of Tlr2 17 0.80 13.82 1.28
78 INT179497 Positive_regulation of Binding of Tlr4 12 0.50 6.49 1.27
79 INT190804 Positive_regulation of Tlr2 6 0.66 3.7 1.16
80 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12
81 INT249522 Positive_regulation of Binding of Src 1 0.22 0.68 1.12
82 INT124167 Regulation of Positive_regulation of Src 2 0.13 0.47 1.1
83 INT131318 Binding of Fabp3 4 0.35 3.33 1.05
84 INT118738 Transcription of Tlr4 4 0.70 1.39 1
85 INT167650 Binding of Ep300 1 0.09 0.14 1
86 INT122347 Transcription of Hsd3b1 1 0.52 0 0.99
87 INT288493 Positive_regulation of Gene_expression of Tlr2 4 0.66 4.38 0.94
88 INT100221 Negative_regulation of Phosphorylation of Src 2 0.24 0.74 0.93
89 INT88032 Negative_regulation of PCSK1 4 0.32 1.27 0.92
90 INT164079 Regulation of Gene_expression of CTGF 4 0.44 2 0.9
91 INT145760 Binding of Tlr2 5 0.46 3.59 0.89
92 INT72944 Positive_regulation of PCSK1 3 0.49 0 0.89
93 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
94 INT153828 Phosphorylation of Fabp3 4 0.44 2.69 0.88
95 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
96 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
97 INT165345 Localization of PCSK1 2 0.48 0.39 0.87
98 INT208243 Positive_regulation of Phosphorylation of Tlr4 5 0.31 3.74 0.86
99 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
100 INT249506 Regulation of Phosphorylation of Src 1 0.13 0.48 0.77
101 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
102 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
103 INT224630 Positive_regulation of Positive_regulation of Tlr2 6 0.46 4.14 0.73
104 INT254115 Negative_regulation of Phosphorylation of Tlr4 5 0.27 3.91 0.71
105 INT228188 Regulation of Gene_expression of Tlr2 5 0.45 6.96 0.71
106 INT161529 Regulation of Gene_expression of Tlr4 3 0.45 2.7 0.69
107 INT186800 Positive_regulation of Binding of TLR4 2 0.47 1.31 0.67
108 INT236785 Regulation of Positive_regulation of TLR4 1 0.32 1.28 0.66
109 INT89616 Gene_expression of FABP3 9 0.78 5.35 0.62
110 INT121076 Regulation of Fabp3 8 0.26 3.66 0.62
111 INT235996 Negative_regulation of Gene_expression of Src 3 0.09 1.29 0.58
112 INT236786 Positive_regulation of Localization of TLR4 2 0.45 1.89 0.57
113 INT204864 Negative_regulation of Negative_regulation of Tlr4 3 0.30 2.05 0.56
114 INT234597 Negative_regulation of Positive_regulation of Tlr2 2 0.30 2.25 0.52
115 INT117998 Positive_regulation of Gene_expression of Src 4 0.36 1.45 0.51
116 INT234587 Positive_regulation of Transcription of Tlr2 3 0.36 1.84 0.51
117 INT62104 Localization of INSIG2 1 0.01 0 0.5
118 INT246926 Negative_regulation of Transcription of Tlr4 3 0.41 1.78 0.49
119 INT343888 Regulation of Regulation of TLR4 1 0.25 1.34 0.49
120 INT158296 Positive_regulation of Gene_expression of Ctgf 5 0.47 4.82 0.47
121 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47
122 INT152229 Positive_regulation of Regulation of Tlr4 2 0.40 0.29 0.46
123 INT122348 Regulation of Hsd3b1 1 0.60 0 0.46
124 INT249504 Localization of Src 1 0.36 0.32 0.46
125 INT140090 Negative_regulation of Gene_expression of Ctgf 5 0.58 1.77 0.44
126 INT89615 Localization of FABP3 5 0.79 3.5 0.42
127 INT185313 Regulation of Transcription of Tlr4 3 0.20 0.49 0.39
128 INT178182 Negative_regulation of Binding of Tlr4 3 0.33 2.13 0.38
129 INT268558 Regulation of CTGF 5 0.23 4.7 0.37
130 INT118736 Positive_regulation of Transcription of Tlr4 1 0.49 0.42 0.35
131 INT119248 Binding of Ctgf 1 0.35 1.5 0.35
132 INT153465 Regulation of Gene_expression of Ctgf 3 0.61 2.5 0.33
133 INT156399 Regulation of Pdx1 1 0.00 0.96 0.33
134 INT249533 Regulation of Localization of Src 1 0.22 0.22 0.32
135 INT230494 Regulation of Binding of Tlr4 3 0.45 2.97 0.31
136 INT168140 Regulation of Ctgf 2 0.60 2.15 0.29
137 INT219162 Localization of CTGF 1 0.50 2.62 0.29
138 INT294476 Negative_regulation of CTGF 1 0.27 1.86 0.29
139 INT164080 Negative_regulation of Gene_expression of CTGF 1 0.41 0.51 0.29
140 INT288189 Negative_regulation of Negative_regulation of Tlr2 1 0.26 0.43 0.28
141 INT136840 Positive_regulation of Ctgf 2 0.35 1.34 0.27
142 INT157768 Negative_regulation of Binding of TLR4 1 0.43 0.29 0.27
143 INT49942 Positive_regulation of Pdx1 5 0.02 1.24 0.26
144 INT288186 Regulation of Binding of Tlr2 2 0.32 1.72 0.26
145 INT224614 Regulation of Positive_regulation of Tlr2 1 0.13 0.56 0.26
146 INT204866 Regulation of Localization of Tlr4 3 0.37 0.66 0.25
147 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
148 INT145758 Regulation of Tlr2 3 0.43 0.94 0.23
149 INT145761 Negative_regulation of Tlr2 2 0.41 1.97 0.23
150 INT215080 Positive_regulation of Negative_regulation of Tlr4 1 0.31 0.05 0.23
151 INT301950 Regulation of Regulation of Tlr4 1 0.40 0.32 0.23
152 INT348772 Positive_regulation of Positive_regulation of Tlr4 1 0.61 0.72 0.21
153 INT115158 Gene_expression of INSIG2 1 0.01 0.33 0.21
154 INT132459 Binding of FABP3 4 0.35 2.19 0.2
155 INT159314 Positive_regulation of Gene_expression of Reln 1 0.44 0.47 0.2
156 INT212787 Negative_regulation of Binding of EP300 1 0.13 0.53 0.2
157 INT256666 Regulation of Gene_expression of EP300 1 0.14 0.07 0.2
158 INT256661 Regulation of Positive_regulation of EP300 1 0.23 0.07 0.2
159 INT325490 Positive_regulation of Ep300 1 0.03 0.22 0.19
160 INT216426 Regulation of UCP2 4 0.09 2.68 0.18
161 INT36325 Negative_regulation of Hmgcl 2 0.05 0.73 0.18
162 INT334246 Positive_regulation of Protein_catabolism of Tlr4 1 0.07 0.18 0.18
163 INT280689 Regulation of Srebf1 1 0.29 0.42 0.17
164 INT306008 Positive_regulation of Transcription of Tlr4 2 0.50 1.41 0.16
165 INT294633 Positive_regulation of Binding of Tlr2 1 0.44 0.42 0.16
166 INT249526 Positive_regulation of Localization of Src 1 0.24 0.1 0.16
167 INT219160 Positive_regulation of CTGF 2 0.29 2.95 0.15
168 INT298653 Positive_regulation of Binding of EP300 1 0.11 0.8 0.15
169 INT289593 Negative_regulation of Ucp2 1 0.44 0.83 0.15
170 INT164161 Regulation of PCSK1 3 0.30 2.09 0.14
171 INT145759 Regulation of Gene_expression of Tlr2 3 0.43 0.98 0.14
172 INT285435 Protein_catabolism of TLR4 2 0.62 0.9 0.14
173 INT246424 Negative_regulation of Transcription of TLR4 2 0.41 0.52 0.14
174 INT301958 Positive_regulation of Regulation of Tlr2 1 0.21 0.32 0.13
175 INT153463 Localization of Ctgf 1 0.65 0.97 0.13
176 INT285441 Regulation of Localization of TLR4 2 0.38 0.15 0.12
177 INT93878 Positive_regulation of Lipc 4 0.47 3.09 0.11
178 INT329058 Positive_regulation of Transcription of Tlr2 1 0.48 0.62 0.11
179 INT329049 Transcription of Tlr2 1 0.68 0.62 0.11
180 INT129082 Positive_regulation of Pik3r1 1 0.00 0.47 0.11
181 INT353249 Positive_regulation of Gene_expression of FABP3 1 0.21 0.73 0.1
182 INT151191 Localization of Fabp3 2 0.32 0.99 0.09
183 INT123875 Localization of Pdx1 1 0.80 0.28 0.09
184 INT265068 Transcription of Reln 1 0.03 0.07 0.09
185 INT70606 Positive_regulation of Positive_regulation of Pdx1 1 0.02 0.4 0.09
186 INT255976 Regulation of Transcription of Tlr2 1 0.22 0.89 0.09
187 INT338740 Transcription of Src 1 0.43 1.24 0.07
188 INT269821 Regulation of Localization of Tlr2 1 0.27 1.04 0.07
189 INT156147 Positive_regulation of Gene_expression of CTGF 1 0.70 0.14 0.07
190 INT46943 Binding of Lipc 2 0.31 1.92 0.06
191 INT276930 Regulation of Regulation of Tlr4 1 0.17 0.45 0.05
192 INT242899 Negative_regulation of Negative_regulation of TLR4 1 0.20 0.09 0.05
193 INT292252 Phosphorylation of EP300 1 0.20 0.55 0.05
194 INT184726 Negative_regulation of Protein_catabolism of Tlr4 2 0.36 0.21 0.04
195 INT228578 Transcription of Ucp2 2 0.29 1.19 0.04
196 INT271818 Negative_regulation of Ctgf 1 0.21 0.41 0.04
197 INT301189 Binding of UCP2 1 0.37 1.39 0.04
198 INT245910 Regulation of Ucp2 1 0.12 0.93 0.04
199 INT245906 Regulation of Transcription of Ucp2 1 0.12 0.93 0.04
200 INT246930 Negative_regulation of Transcription of Tlr2 1 0.36 0.92 0.04
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