GO:0070947

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Name neutrophil mediated killing of fungus
Categary Process
Go Slim No
Go Link GO:0070947
Unique Molecular Interactions 125
Total Molecular Interactions 174
Total Single Events 1026
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neutrophil mediated killing of fungus. They are ordered first by their pain relevance and then by number of times they were reported for neutrophil mediated killing of fungus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
2 INT62019 CSF2 Regulation of ELANE 1 0.03 0.47 1.21
3 INT312097 ELANE Regulation of ALOX5 1 0.08 1.75 1.05
4 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04
5 INT62017 ELANE Positive_regulation of Localization of ACOT1 1 0.05 0.35 0.98
6 INT13193 FPR1 Positive_regulation of ELANE 3 0.44 1.22 0.92
7 INT32441 POMC Positive_regulation of ELANE 1 0.13 0.09 0.83
8 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
9 INT312101 ELANE Regulation of ALOX5AP 1 0.21 1.11 0.73
10 INT293010 ELANE Regulation of Localization of LTF 1 0.00 0.54 0.67
11 INT312105 ELANE Positive_regulation of Localization of PTGER2 4 0.03 1.3 0.64
12 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62
13 INT32782 Binding of Vip and Elane 1 0.17 0 0.61
14 INT57248 ELANE Regulation of Gene_expression of CGA 1 0.05 0 0.52
15 INT312118 ELANE Regulation of PTGES 1 0.22 0.92 0.49
16 INT65006 DAK Negative_regulation of ELANE 1 0.05 0.35 0.47
17 INT312112 ELANE Regulation of Transcription of ALOX5 1 0.09 0.82 0.47
18 INT221026 ELANE Positive_regulation of Gene_expression of CCL18 1 0.01 0.57 0.45
19 INT56631 Negative_regulation of FPR1 Positive_regulation of ELANE 1 0.38 0.54 0.44
20 INT353331 Elane Positive_regulation of F2r 1 0.08 0.78 0.44
21 INT293007 IRF6 Positive_regulation of ELANE 1 0.00 0 0.42
22 INT221027 ELANE Positive_regulation of IL8 2 0.14 1.3 0.4
23 INT312123 ELANE Positive_regulation of ALOX5 1 0.09 0.74 0.4
24 INT312122 ELANE Positive_regulation of Protein_catabolism of COL2A1 1 0.05 0.65 0.39
25 INT312086 ELANE Positive_regulation of MMP13 1 0.13 0.64 0.39
26 INT312750 Elane Positive_regulation of Positive_regulation of Ltp 1 0.01 0.38 0.34
27 INT312119 ELANE Positive_regulation of Gene_expression of PTGES 1 0.18 0.74 0.33
28 INT312099 ELANE Positive_regulation of Gene_expression of PTGER2 1 0.02 0.64 0.32
29 INT346286 ELANE Positive_regulation of MAPK1 1 0.06 0.65 0.32
30 INT346281 Binding of ELANE and MAPK1 1 0.04 0.65 0.32
31 INT312085 ELANE Regulation of Regulation of ALOX5 1 0.09 0.64 0.32
32 INT190826 ELANE Positive_regulation of Localization of MUC1 1 0.07 0 0.29
33 INT116358 Binding of C3 and ELANE 1 0.12 0 0.29
34 INT116356 Positive_regulation of Binding of C3 and ELANE 1 0.16 0 0.29
35 INT312115 ELANE Positive_regulation of Transcription of PTGES 1 0.25 0.53 0.25
36 INT312569 IL6 Positive_regulation of Localization of ELANE 1 0.11 1.05 0.24
37 INT15829 Ambp Regulation of Positive_regulation of ELANE 1 0.00 0 0.24
38 INT202422 IL8 Positive_regulation of Localization of ELANE 1 0.02 0.91 0.24
39 INT222178 SERPINB1 Regulation of ELANE 1 0.00 1.04 0.23
40 INT259623 Binding of Eln and Elane 1 0.02 1.38 0.23
41 INT133166 ELANE Regulation of Tnf 1 0.01 0.98 0.22
42 INT57250 ELANE Positive_regulation of Localization of CGA 1 0.08 0 0.21
43 INT310939 Binding of ELANE and COPD 1 0.08 1.51 0.2
44 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2
45 INT310938 Binding of ELANE and HRCT1 1 0.02 1.5 0.2
46 INT259634 Elane Positive_regulation of Gene_expression of COPD 1 0.01 0.92 0.17
47 INT221025 TNF Positive_regulation of ELANE 1 0.01 0.13 0.17
48 INT346305 Binding of ELANE and Col2a1 1 0.00 0.98 0.17
49 INT215270 Binding of Ncf1 and Ncf4 1 0.05 0.38 0.17
50 INT312109 ELANE Positive_regulation of EGR1 1 0.15 0.23 0.16
51 INT312100 ELANE Positive_regulation of Binding of EGR1 1 0.16 0.23 0.16
52 INT312111 ELANE Regulation of Transcription of PTGES 1 0.22 0.23 0.16
53 INT116359 Positive_regulation of Binding of C4A and ELANE 1 0.14 0 0.15
54 INT221030 ELANE Positive_regulation of CXCL10 1 0.01 0.24 0.15
55 INT312126 ELANE Positive_regulation of ALOX5AP 1 0.20 0.25 0.15
56 INT22820 ADRA1D Regulation of ELANE 1 0.21 0 0.15
57 INT312092 ELANE Positive_regulation of Gene_expression of EGR1 1 0.19 0.21 0.15
58 INT221035 ELANE Positive_regulation of CCL18 1 0.01 0.24 0.15
59 INT21453 Ambp Regulation of ELANE 1 0.00 0 0.15
60 INT221019 ELANE Positive_regulation of CCL3 1 0.00 0.24 0.15
61 INT116357 Binding of C4A and ELANE 1 0.11 0 0.14
62 INT312096 ELANE Positive_regulation of Transcription of ALOX5 1 0.06 0.27 0.13
63 INT252785 ELANE Regulation of Gene_expression of FBRS 1 0.00 0.5 0.13
64 INT179234 Binding of SERPINA6 and ELANE 1 0.01 0.22 0.12
65 INT312570 AMBP Regulation of Negative_regulation of ELANE 1 0.06 0.95 0.12
66 INT215283 Tlr4 Positive_regulation of Localization of Ncf1 2 0.05 1.04 0.11
67 INT191759 NFASC Negative_regulation of ELANE 1 0.00 0.98 0.11
68 INT312094 ELANE Positive_regulation of PTGES 1 0.29 0.34 0.11
69 INT324828 ELANE Positive_regulation of Localization of Ecm1 1 0.00 0.61 0.09
70 INT312103 ELANE Regulation of Gene_expression of ALOX5 1 0.06 0.15 0.08
71 INT24660 Positive_regulation of Binding of ELANE and SERPINA1 1 0.17 0.73 0.08
72 INT259622 Elane Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.38 0.08
73 INT312093 ELANE Regulation of Gene_expression of ALOX5AP 1 0.13 0.15 0.08
74 INT21452 Ambp Regulation of Gene_expression of ELANE 1 0.00 0 0.08
75 INT56377 AMBP Negative_regulation of Elane 1 0.00 1.43 0.08
76 INT249166 Phosphorylation of NCF1 Positive_regulation of Localization of GOPC 1 0.03 0.06 0.08
77 INT24659 Binding of ELANE and SERPINA1 1 0.13 0.73 0.08
78 INT312113 ELANE Positive_regulation of Gene_expression of ALOX5AP 1 0.23 0.14 0.07
79 INT346302 ELANE Regulation of Col2a1 1 0.00 0.3 0.05
80 INT339020 SERPINA1 Negative_regulation of ELANE 1 0.07 0.59 0.05
81 INT257339 Lox Regulation of Ncf1 1 0.02 0.37 0.05
82 INT312110 ELANE Positive_regulation of Gene_expression of ALOX5 1 0.09 0.07 0.04
83 INT346283 Binding of COL11A1 and ELANE 1 0.01 0.08 0.04
84 INT312117 Negative_regulation of ELANE Positive_regulation of ALOX5AP 1 0.17 0.08 0.04
85 INT179903 Binding of ELANE and SRI 1 0.17 1.07 0.03
86 INT312125 Binding of ELANE and PTGES 1 0.13 0.07 0.03
87 INT252820 ELANE Positive_regulation of Gene_expression of COL1A1 1 0.01 0.58 0
88 INT179904 Positive_regulation of ELANE Positive_regulation of NYS3 1 0.10 0.92 0
89 INT238402 ELANE Positive_regulation of Gene_expression of CDKN1A 1 0.03 0.48 0
90 INT238396 ELANE Regulation of PPARA 1 0.04 0.65 0
91 INT252796 ELANE Regulation of COL1A1 1 0.01 0.57 0
92 INT325997 Binding of Cybb and Ncf1 1 0.18 0.77 0
93 INT252798 ELANE Regulation of Gene_expression of ROS1 1 0.04 0.16 0
94 INT280845 Binding of ELANE and Avp 1 0.06 0 0
95 INT312107 ELANE Positive_regulation of Gene_expression of COX18 1 0.04 0 0
96 INT238406 Binding of ELANE and PPARA 1 0.07 0.43 0
97 INT252775 ELANE Regulation of Gene_expression of MMRN1 1 0.01 0.16 0
98 INT254512 Binding of CYBB and NCF1 1 0.07 0.14 0
99 INT346284 Binding of ELANE and MR1 1 0.00 0.31 0
100 INT324878 Ncf1 Positive_regulation of CYBB 1 0.01 0.25 0
101 INT179905 Positive_regulation of ELANE Positive_regulation of SRI 1 0.19 0.92 0
102 INT252771 ELANE Regulation of FBN1 1 0.00 0.57 0
103 INT311063 ELANE Positive_regulation of HSF1 1 0.18 0.54 0
104 INT238405 ELANE Positive_regulation of PPARA 1 0.08 0.46 0
105 INT252813 ELANE Positive_regulation of COL1A1 1 0.01 0.57 0
106 INT257345 Ncf1 Positive_regulation of Gene_expression of Ros1 1 0.08 0.58 0
107 INT252811 ELANE Regulation of FUT1 1 0.01 0.57 0
108 INT312120 ELANE Regulation of Localization of PTGER2 1 0.03 0 0
109 INT209391 Binding of ELANE and Cpox 1 0.01 0.25 0
110 INT238398 ELANE Positive_regulation of Gene_expression of BAX 1 0.05 0.47 0
111 INT311062 ELANE Positive_regulation of Localization of HSF1 1 0.22 0.91 0
112 INT312098 ELANE Regulation of Gene_expression of COX18 1 0.05 0 0
113 INT326002 Binding of Cyba and Ncf1 1 0.09 0.77 0
114 INT238399 ELANE Positive_regulation of SRA1 1 0.01 0.07 0
115 INT280847 Avp Regulation of Binding of ELANE 1 0.07 0 0
116 INT257347 Binding of Cyba and Ncf1 1 0.17 0.29 0
117 INT238390 ELANE Positive_regulation of Gene_expression of TP53 1 0.04 0.42 0
118 INT252776 ELANE Regulation of Gene_expression of COL1A1 1 0.01 0.58 0
119 INT252819 ELANE Positive_regulation of Localization of ROS1 1 0.04 0.05 0
120 INT238391 ELANE Positive_regulation of PCNA 1 0.01 0.07 0
121 INT269067 Nox4 Negative_regulation of Localization of Ncf1 1 0.17 0 0
122 INT311060 ELANE Regulation of Localization of HSF1 1 0.20 0.74 0
123 INT238403 PPARA Regulation of ELANE 1 0.04 0.65 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for neutrophil mediated killing of fungus. They are ordered first by their pain relevance and then by number of times they were reported in neutrophil mediated killing of fungus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94
2 INT2609 Localization of ELANE 111 0.81 50.22 26.63
3 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09
4 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79
5 INT2605 Regulation of ELANE 39 0.61 18.22 7.11
6 INT116420 Localization of Elane 16 0.14 7.8 6
7 INT10100 Binding of ELANE 22 0.47 15.32 5.19
8 INT17582 Negative_regulation of Localization of ELANE 17 0.53 6.11 4.89
9 INT179656 Gene_expression of Elane 12 0.32 9.44 3.53
10 INT22891 Positive_regulation of Localization of ELANE 16 0.69 11.52 3.42
11 INT42581 Regulation of Gene_expression of ELANE 11 0.38 9.25 3.38
12 INT22823 Positive_regulation of Positive_regulation of ELANE 12 0.45 6.89 3.35
13 INT25674 Positive_regulation of Gene_expression of ELANE 16 0.60 7.46 3.12
14 INT28731 Negative_regulation of Elane 14 0.14 8.97 3.01
15 INT197030 Gene_expression of Ncf1 16 0.78 11.5 2.58
16 INT124583 Negative_regulation of Elane 8 0.29 5.26 2.14
17 INT42583 Protein_catabolism of ELANE 8 0.89 4.33 2.11
18 INT51502 Positive_regulation of Elane 5 0.22 2.3 1.94
19 INT36245 Negative_regulation of Gene_expression of ELANE 11 0.40 5.32 1.88
20 INT83358 Positive_regulation of Elane 8 0.21 8.14 1.83
21 INT174656 Binding of NCF1 5 0.37 6.46 1.65
22 INT242902 Gene_expression of NCF1 12 0.78 9.34 1.36
23 INT21167 Regulation of NCF1 3 0.15 0.75 1.24
24 INT5652 Negative_regulation of Positive_regulation of ELANE 7 0.37 2.46 1.21
25 INT199090 Localization of Ncf1 14 0.41 5.14 1.18
26 INT128970 Localization of Ncf1 6 0.68 4.25 1.1
27 INT17805 Regulation of Localization of ELANE 7 0.59 1.88 1.08
28 INT32443 Negative_regulation of Binding of ELANE 2 0.11 0.54 0.89
29 INT203132 Negative_regulation of Gene_expression of Elane 1 0.20 1.5 0.86
30 INT116419 Negative_regulation of Localization of Elane 2 0.01 0.58 0.82
31 INT203739 Negative_regulation of NCF1 2 0.27 1.22 0.82
32 INT197032 Regulation of Ncf1 3 0.45 2.84 0.79
33 INT142422 Regulation of Positive_regulation of ELANE 1 0.02 0.65 0.78
34 INT46295 Regulation of Negative_regulation of ELANE 4 0.39 2.34 0.76
35 INT215261 Negative_regulation of Localization of Ncf1 6 0.30 3.51 0.74
36 INT260352 Positive_regulation of Gene_expression of NCF1 1 0.50 3.34 0.69
37 INT153008 Gene_expression of Elane 3 0.66 1.66 0.67
38 INT51501 Positive_regulation of Positive_regulation of Elane 1 0.09 0.5 0.59
39 INT199096 Phosphorylation of Ncf1 8 0.42 1.55 0.53
40 INT179665 Protein_catabolism of Elane 3 0.15 3.19 0.52
41 INT179666 Positive_regulation of Gene_expression of Elane 3 0.21 1.84 0.5
42 INT197037 Negative_regulation of Ncf1 1 0.43 1.49 0.49
43 INT153430 Binding of Elane 2 0.47 1.92 0.48
44 INT235200 Positive_regulation of Negative_regulation of ELANE 3 0.38 1.68 0.46
45 INT142324 Gene_expression of Ncf1 19 0.75 10.8 0.41
46 INT252736 Transcription of ELANE 2 0.25 0.94 0.39
47 INT52071 Negative_regulation of Negative_regulation of ELANE 2 0.13 0.78 0.36
48 INT21451 Regulation of Regulation of ELANE 2 0.07 0.06 0.35
49 INT199073 Positive_regulation of Ncf1 7 0.27 3.64 0.31
50 INT273175 Negative_regulation of Gene_expression of Elane 1 0.04 0.71 0.29
51 INT260350 Negative_regulation of Gene_expression of NCF1 1 0.43 1.47 0.27
52 INT185122 Regulation of Localization of Elane 1 0.01 0.12 0.27
53 INT199094 Positive_regulation of Phosphorylation of Ncf1 2 0.36 0.55 0.26
54 INT273176 Positive_regulation of Gene_expression of Elane 1 0.04 0.63 0.26
55 INT272891 Positive_regulation of Positive_regulation of Elane 1 0.08 1.01 0.25
56 INT199092 Binding of Ncf1 3 0.19 0.43 0.24
57 INT272872 Positive_regulation of Protein_catabolism of Elane 1 0.08 1 0.24
58 INT259604 Positive_regulation of Binding of Elane 1 0.09 0.81 0.23
59 INT179450 Positive_regulation of NCF1 5 0.50 1.04 0.17
60 INT199069 Positive_regulation of Transcription of Ncf1 2 0.19 0.37 0.17
61 INT259617 Negative_regulation of Binding of Elane 1 0.08 0.67 0.16
62 INT111240 Localization of Elane 1 0.78 0.59 0.15
63 INT111241 Negative_regulation of Localization of Elane 1 0.57 0.59 0.15
64 INT257331 Positive_regulation of Gene_expression of Ncf1 6 0.33 2.39 0.14
65 INT249250 Phosphorylation of NCF1 1 0.24 0.14 0.14
66 INT249269 Positive_regulation of Phosphorylation of NCF1 1 0.15 0.14 0.14
67 INT272869 Negative_regulation of Negative_regulation of Elane 1 0.06 1.02 0.14
68 INT257322 Transcription of Ncf1 3 0.33 1.13 0.13
69 INT312139 Regulation of Transcription of ELANE 1 0.16 0.18 0.13
70 INT322980 Positive_regulation of Localization of Ncf1 2 0.33 0.37 0.09
71 INT249267 Positive_regulation of Localization of NCF1 2 0.14 0.53 0.09
72 INT199062 Transcription of Ncf1 2 0.19 0.18 0.08
73 INT249265 Localization of NCF1 3 0.21 1.12 0.07
74 INT249243 Negative_regulation of Positive_regulation of NCF1 1 0.13 0.08 0.07
75 INT249253 Negative_regulation of Phosphorylation of NCF1 1 0.13 0.08 0.07
76 INT83359 Regulation of Elane 2 0.11 3.61 0.05
77 INT179651 Negative_regulation of Protein_catabolism of Elane 1 0.04 0.75 0.05
78 INT336597 Regulation of Ncf1 1 0.12 0.52 0.04
79 INT260351 Regulation of Gene_expression of NCF1 1 0.27 0.84 0.04
80 INT257326 Positive_regulation of Ncf1 3 0.33 1.21 0.03
81 INT199100 Positive_regulation of Gene_expression of Ncf1 2 0.19 0.83 0.03
82 INT287710 Regulation of Regulation of Elane 1 0.11 1.38 0.03
83 INT354470 Negative_regulation of Localization of Ncf1 1 0.28 0.77 0.03
84 INT257324 Negative_regulation of Gene_expression of Ncf1 1 0.26 0.13 0.03
85 INT199091 Negative_regulation of Gene_expression of Ncf1 1 0.12 0.09 0.03
86 INT70328 Phosphorylation of ELANE 2 0.29 0.15 0
87 INT197033 Binding of Ncf1 1 0.32 0.06 0
88 INT254549 Negative_regulation of Localization of NCF1 1 0.12 0.69 0
89 INT197029 Protein_catabolism of Ncf1 1 0.77 0.08 0
90 INT249256 Positive_regulation of Positive_regulation of NCF1 1 0.15 0 0
91 INT322979 Positive_regulation of Phosphorylation of Ncf1 1 0.33 0.7 0
92 INT235206 Positive_regulation of Localization of Ncf1 1 0.22 0.25 0
93 INT322978 Phosphorylation of Ncf1 1 0.39 0.35 0
94 INT257332 Regulation of Localization of Ncf1 1 0.17 0.54 0
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