GO:0090004

Name positive regulation of establishment of protein localization in plasma membrane Categary Process Go Slim No Go Link GO:0090004

Unique Molecular Interactions 672 Total Molecular Interactions 912 Total Single Events 5842 Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of establishment of protein localization in plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of establishment of protein localization in plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT132225	Negative_regulation of Binding of Akt1 and Sh2d6	1	0.10	3.92	7.2
2	INT180813	Ngf Positive_regulation of Sorbs1	1	0.04	2.09	3.79
3	INT132231	Negative_regulation of Binding of Akt1 and Pik3cg	1	0.34	1.96	3.6
4	INT317522	Akt1 Positive_regulation of Phosphorylation of Nos1	1	0.43	0.4	3.13
5	INT168758	Hist1h1t Positive_regulation of Phosphorylation of Akt1	2	0.02	0.44	2.79
6	INT317551	Binding of Akt1 and Oprm1	1	0.19	0.21	2.74
7	INT121726	Ngf Positive_regulation of Phosphorylation of Akt1	1	0.37	1.4	2.34
8	INT114432	Oprl1 Positive_regulation of Akt1	1	0.18	0.08	2.2
9	INT151965	SORBS1 Positive_regulation of TRPV1	1	0.18	0	1.89
10	INT132229	Binding of Akt1 and Sh2d6	1	0.09	0.98	1.8
11	INT169464	Akt1 Positive_regulation of Egfr	1	0.28	1.63	1.7
12	INT122428	Binding of Ighm and Prkci	1	0.00	0	1.66
13	INT322412	PPBP Negative_regulation of Phosphorylation of Akt1	1	0.01	0	1.65
14	INT180812	Gdnf Positive_regulation of Gene_expression of Sorbs1	1	0.02	0.83	1.61
15	INT180811	Gdnf Positive_regulation of Regulation of Sorbs1	1	0.01	0.83	1.61
16	INT180804	Bdnf Positive_regulation of Gene_expression of Sorbs1	1	0.01	0	1.44
17	INT214372	Ptprq Positive_regulation of Akt1	1	0.04	0.88	1.43
18	INT214369	Pik3cb Positive_regulation of Akt1	1	0.56	0.87	1.41
19	INT180809	Ngf Positive_regulation of Positive_regulation of Sorbs1	1	0.03	0.84	1.4
20	INT180808	Ngf Positive_regulation of Gene_expression of Sorbs1	1	0.03	0.84	1.4
21	INT122430	Negative_regulation of Binding of Ighm and Prkci	1	0.00	0	1.36
22	INT180802	Gdnf Positive_regulation of Sorbs1	1	0.02	0.98	1.34
23	INT180807	Calca Regulation of Sorbs1	1	0.02	0	1.32
24	INT153589	Binding of PRKCI and Oprm1	1	0.06	0	1.17
25	INT68157	Alox5 Positive_regulation of Positive_regulation of Pdpk1	1	0.01	0.64	1.13
26	INT68154	Mthfs Positive_regulation of Pdpk1	1	0.01	0.63	1.12
27	INT68158	Pla2g1b Positive_regulation of Pdpk1	1	0.05	0.63	1.12
28	INT68159	Pla2g1b Positive_regulation of Positive_regulation of Pdpk1	1	0.05	0.64	1.12
29	INT68163	Mthfs Positive_regulation of Positive_regulation of Pdpk1	1	0.01	0.64	1.12
30	INT68165	Alox5 Positive_regulation of Pdpk1	1	0.01	0.63	1.12
31	INT317548	Positive_regulation of Akt1 Positive_regulation of Prkca	1	0.15	0	1.11
32	INT317516	Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1	1	0.17	0.1	1.11
33	INT99691	Pdpk1 Positive_regulation of Positive_regulation of VEGFA	1	0.01	0.72	1.11
34	INT323175	PRKCA Positive_regulation of Akt1	1	0.02	0	1.1
35	INT108547	AKT1 Regulation of MAPKAPK5	1	0.04	1.2	1.08
36	INT122432	Prkci Regulation of Negative_regulation of Oprd1	1	0.01	0	1.06
37	INT180806	Ngf Positive_regulation of Regulation of Sorbs1	1	0.03	0.28	1.04
38	INT151218	Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1	1	0.00	0.26	1.03
39	INT122429	Prkci Regulation of Gene_expression of Ighm	1	0.00	0	1.02
40	INT122431	Prkci Negative_regulation of Negative_regulation of Ighm	1	0.00	0	1.02
41	INT122433	Prkci Negative_regulation of Ighm	1	0.00	0	1.02
42	INT317554	Akt1 Regulation of Negative_regulation of Oprm1	1	0.21	0.07	1
43	INT317567	Binding of Akt1 and Nos1	1	0.22	0	0.96
44	INT180803	Sorbs1 Regulation of Gdnf	1	0.01	0.28	0.95
45	INT137923	VEGFA Positive_regulation of Phosphorylation of Akt1	1	0.05	0	0.93
46	INT107335	Pdpk1 Positive_regulation of Regulation of Sigmar1	1	0.02	0	0.93
47	INT114883	Akt1 Regulation of Pik3r1	2	0.16	0.65	0.92
48	INT317541	Oprd1 Negative_regulation of Akt1	1	0.06	0	0.91
49	INT249012	Binding of Akt1 and Gabrg1	1	0.01	0	0.9
50	INT132226	Binding of Akt1 and Pik3cg	1	0.30	0.49	0.9
51	INT54854	Sorbs1 Regulation of Ins1	1	0.34	0.23	0.9
52	INT199109	Binding of Akt1 and Arhgdia	1	0.02	2.73	0.87
53	INT69084	Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1	1	0.02	0.08	0.83
54	INT116106	VEGFA Positive_regulation of AKT1	1	0.12	0.3	0.83
55	INT317556	Phosphorylation of Gopc Positive_regulation of Akt1	1	0.10	0.08	0.82
56	INT317514	Akt1 Regulation of Localization of Oprm1	1	0.21	0.07	0.82
57	INT228255	Binding of Akt1 and Pten	2	0.43	1.78	0.8
58	INT111888	Akt1 Regulation of Regulation of Oprm1	1	0.04	0	0.77
59	INT134043	Jak2 Positive_regulation of Akt1	1	0.31	0.22	0.76
60	INT335592	Ltp Positive_regulation of Positive_regulation of Akt1	1	0.01	0.19	0.74
61	INT162164	ARF6 Regulation of Positive_regulation of PLD2	1	0.60	0	0.74
62	INT106527	Akt1 Positive_regulation of Jun	1	0.05	0.53	0.74
63	INT276213	Pten Regulation of Phosphorylation of Akt1	1	0.51	0.61	0.72
64	INT162162	ARF6 Regulation of OPRM1	1	0.19	0	0.71
65	INT180805	Bdnf Regulation of Sorbs1	1	0.01	0.14	0.67
66	INT298728	Akt1 Positive_regulation of Rela	1	0.01	1.03	0.67
67	INT289357	Ngfr Positive_regulation of Akt1	1	0.03	3.1	0.66
68	INT308668	Akt1 Positive_regulation of Nos3	3	0.05	4.61	0.65
69	INT296793	Akt1 Positive_regulation of Gene_expression of Bax	1	0.11	0.75	0.65
70	INT296791	Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax	1	0.11	0.8	0.65
71	INT317560	Binding of Pdpk1 and Pik3r1	1	0.13	0	0.65
72	INT169293	PTPLA Positive_regulation of AKT1	1	0.10	0.15	0.64
73	INT134047	Fitm1 Positive_regulation of Phosphorylation of Akt1	1	0.05	0.21	0.63
74	INT134044	Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1	1	0.05	0.21	0.63
75	INT278695	MTX1 Negative_regulation of Phosphorylation of AKT1	1	0.04	0.81	0.62
76	INT200808	Binding of Akt1 and Insrr	2	0.00	0.98	0.61
77	INT282286	Akt1 Positive_regulation of Pak1	1	0.15	0.24	0.61
78	INT139901	Ins1 Positive_regulation of Akt1	9	0.31	4.58	0.6
79	INT248994	Binding of Akt1 and Ptar1	1	0.00	0	0.58
80	INT323176	PRKCA Positive_regulation of Phosphorylation of Akt1	1	0.02	0	0.56
81	INT302832	Tnfsf10 Positive_regulation of Akt1	1	0.04	1.63	0.56
82	INT201944	CXCL10 Positive_regulation of Phosphorylation of AKT1	1	0.09	0.79	0.55
83	INT114064	Agtr2 Positive_regulation of Phosphorylation of Akt1	1	0.24	0.41	0.54
84	INT282284	Cpox Positive_regulation of Akt1	1	0.02	0.47	0.54
85	INT282282	Ptger2 Positive_regulation of Akt1	1	0.03	0.47	0.54
86	INT162994	Binding of Akt1 and Trib3	1	0.04	0.09	0.54
87	INT127320	Gpx3 Regulation of Akt1	2	0.00	3.11	0.53
88	INT317523	Oprm1 Positive_regulation of Gene_expression of Akt1	1	0.32	0.05	0.53
89	INT5631	Ubqln1 Positive_regulation of Pdpk1	1	0.05	0	0.53
90	INT109307	Pik3r1 Positive_regulation of Phosphorylation of Akt1	1	0.29	0.4	0.53
91	INT317574	Oprm1 Positive_regulation of Akt1	1	0.22	0.05	0.52
92	INT97952	Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1	1	0.03	0.72	0.51
93	INT151221	Negative_regulation of SIGMAR1 Negative_regulation of Akt1	1	0.00	0.13	0.51
94	INT97951	ST3GAL3 Positive_regulation of AKT1	1	0.04	0.7	0.5
95	INT102844	Pdc Regulation of Akt1	1	0.03	0	0.49
96	INT259180	Pdpk1 Positive_regulation of Gene_expression of Gria1	1	0.02	0.4	0.49
97	INT259181	Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1	1	0.02	0.4	0.49
98	INT134042	Jak2 Regulation of Akt1	1	0.18	0.13	0.47
99	INT309126	Edc4 Positive_regulation of Akt1	1	0.02	0.99	0.47
100	INT309144	Dlat Positive_regulation of Akt1	1	0.03	0.99	0.47
101	INT276207	Binding of Akt1 and Myo1f	1	0.11	0.05	0.47
102	INT162932	TXNRD1 Negative_regulation of Phosphorylation of AKT1	1	0.14	1.01	0.47
103	INT114065	Akt1 Regulation of Gene_expression of Insr	1	0.13	0.28	0.46
104	INT276218	Binding of Akt1 and Pten	1	0.26	0.08	0.46
105	INT95469	P2ry6 Positive_regulation of Positive_regulation of Pdpk1	1	0.15	0	0.46
106	INT162929	NQO1 Negative_regulation of Phosphorylation of AKT1	1	0.41	1	0.46
107	INT139900	Kcne2 Positive_regulation of Akt1	1	0.06	2.95	0.44
108	INT15024	Prkcg Regulation of Pdpk1	1	0.09	0	0.43
109	INT151184	Pdpk1 Positive_regulation of Trpv1	1	0.08	0	0.42
110	INT151183	Pdpk1 Positive_regulation of Phosphorylation of Trpv1	1	0.08	0	0.42
111	INT160047	PTEN Regulation of Gene_expression of AKT1	1	0.33	0.6	0.42
112	INT348785	Ins1 Positive_regulation of Phosphorylation of Akt1	1	0.17	3.5	0.42
113	INT322396	Hist1h1t Positive_regulation of Akt1	1	0.01	0	0.42
114	INT160048	INPPL1 Regulation of Gene_expression of AKT1	1	0.28	0.6	0.42
115	INT322395	Akt1 Regulation of Pik3cb	1	0.08	0	0.42
116	INT121851	AKT1 Regulation of ROS1	1	0.16	0.52	0.41
117	INT122749	Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1	1	0.07	0.24	0.41
118	INT121848	AKT1 Regulation of CASP8	1	0.18	0.52	0.41
119	INT121854	AKT1 Regulation of BID	1	0.17	0.52	0.41
120	INT276216	Binding of Akt1 and Ins1	2	0.03	2.61	0.4
121	INT108197	AKT1 Regulation of JUN	1	0.29	0.25	0.4
122	INT231842	Pcdh8 Positive_regulation of Akt1	1	0.00	1.59	0.4
123	INT121853	Gene_expression of ROS1 Negative_regulation of AKT1	1	0.25	0.49	0.4
124	INT322409	Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1	1	0.04	0	0.4
125	INT166155	Ccr9 Positive_regulation of Akt1	1	0.58	2.14	0.39
126	INT236111	Binding of Pdpk1 and Ppara	1	0.26	1.21	0.39
127	INT146611	Ins1 Positive_regulation of Phosphorylation of Akt1	9	0.23	4.34	0.37
128	INT89386	INS Positive_regulation of Phosphorylation of AKT1	3	0.43	1.48	0.36
129	INT299288	AKT1 Positive_regulation of RPTOR	1	0.34	0.05	0.36
130	INT112617	Pdpk1 Regulation of Il1b	1	0.03	1.11	0.36
131	INT112618	Pdpk1 Regulation of Tnf	1	0.03	1.11	0.36
132	INT148243	Binding of Akt1 and Kit	1	0.03	0.44	0.35
133	INT122758	Positive_regulation of Helt Positive_regulation of Akt1	1	0.00	0.2	0.35
134	INT288208	Binding of Mapk14 and Positive_regulation of Akt1	1	0.01	0.42	0.35
135	INT176135	AKT1 Regulation of Localization of CYCS	1	0.43	2.16	0.35
136	INT122756	Helt Positive_regulation of Akt1	1	0.00	0.2	0.35
137	INT309118	Dlat Positive_regulation of Positive_regulation of Akt1	1	0.03	0.32	0.34
138	INT249019	Gabrg1 Positive_regulation of Akt1	1	0.02	0	0.34
139	INT196820	Negative_regulation of Ppp1cc Positive_regulation of Akt1	1	0.00	0	0.34
140	INT89381	INS Positive_regulation of AKT1	6	0.43	3.06	0.33
141	INT222721	Binding of HTR1A and Pdpk1	1	0.00	0.35	0.33
142	INT214377	Akt1 Regulation of Amph	1	0.15	0	0.33
143	INT165580	Binding of Akt1 and Grin2b	1	0.02	0.2	0.32
144	INT337410	AKT3 Negative_regulation of AKT1	1	0.09	0.49	0.32
145	INT337414	AKT2 Negative_regulation of AKT1	1	0.10	0.5	0.32
146	INT255740	Pik3r1 Positive_regulation of Akt1	5	0.24	2.42	0.31
147	INT303063	Akt1 Negative_regulation of Gene_expression of Syn1	1	0.09	0.45	0.31
148	INT165921	Tlr4 Positive_regulation of Akt1	1	0.16	0.75	0.31
149	INT165920	Negative_regulation of Tlr4 Positive_regulation of Akt1	1	0.13	0.75	0.31
150	INT299307	AKT1 Positive_regulation of Positive_regulation of AKT1S1	1	0.10	0	0.3
151	INT299289	AKT1 Positive_regulation of Positive_regulation of TSC2	1	0.17	0	0.3
152	INT122575	Akt1 Positive_regulation of Phosphorylation of Nos3	4	0.37	3.89	0.29
153	INT291202	Positive_regulation of INS Positive_regulation of AKT1	1	0.01	0.76	0.29
154	INT132367	Lgals1 Positive_regulation of Akt1	1	0.22	0.13	0.28
155	INT317533	Akt1 Positive_regulation of Nos1	1	0.43	0	0.28
156	INT149322	Amph Positive_regulation of Akt1	1	0.39	0	0.27
157	INT18994	Negative_regulation of Pdpk1 Negative_regulation of Regulation of Cck	1	0.10	0	0.26
158	INT223930	Binding of Akt1 and Pik3cb	1	0.07	0.35	0.26
159	INT223929	Negative_regulation of Binding of Akt1 and Pik3cb	1	0.08	0.36	0.26
160	INT303082	Akt1 Negative_regulation of Gene_expression of Mafk	1	0.20	0.37	0.26
161	INT308661	Akt1 Positive_regulation of Chuk	1	0.02	0.6	0.25
162	INT314047	THL Negative_regulation of Phosphorylation of Akt1	1	0.14	0.71	0.25
163	INT326094	Akt1 Positive_regulation of Gene_expression of Gopc	1	0.03	0.49	0.24
164	INT326092	Gene_expression of Akt1 Negative_regulation of Gopc	1	0.03	0.55	0.24
165	INT326093	Akt1 Positive_regulation of Gopc	1	0.03	0.43	0.23
166	INT265886	IGF1 Positive_regulation of AKT1	1	0.11	3.06	0.23
167	INT323173	THRA Positive_regulation of Phosphorylation of Akt1	1	0.00	0	0.22
168	INT260844	NRP2 Positive_regulation of Akt1	1	0.00	0.73	0.22
169	INT116467	Vegfa Positive_regulation of Akt1	1	0.33	1.41	0.21
170	INT323174	DBT Positive_regulation of Phosphorylation of Akt1	1	0.01	0	0.21
171	INT120716	Binding of AKT1 and TEP1	1	0.05	0.46	0.21
172	INT116468	VEGFA Positive_regulation of Akt1	1	0.04	1.39	0.21
173	INT289356	Binding of Akt1 and Fgf2	1	0.03	0.82	0.21
174	INT309661	C5 Positive_regulation of Phosphorylation of Akt1	1	0.51	0.45	0.21
175	INT221237	Prkca Regulation of Phosphorylation of Akt1	1	0.01	0.28	0.2
176	INT224688	Pten Regulation of Akt1	1	0.04	1.12	0.19
177	INT58006	DYT10 Positive_regulation of Positive_regulation of Pdpk1	1	0.02	0.14	0.18
178	INT334631	Igf1r Positive_regulation of Phosphorylation of Akt1	1	0.19	0.5	0.18
179	INT303058	Akt1 Negative_regulation of Gene_expression of Syt1	1	0.21	0.43	0.18
180	INT221231	Pdpk1 Positive_regulation of Akt1	1	0.09	0.13	0.18
181	INT221244	Pdpk1 Positive_regulation of Phosphorylation of Akt1	1	0.09	0.13	0.18
182	INT298192	EGFR Positive_regulation of AKT1	1	0.10	0.65	0.18
183	INT121582	AKT1 Regulation of Gene_expression of GDF15	1	0.21	0.4	0.18
184	INT318324	Binding of AKT1 and PRKCA	1	0.03	0.63	0.18
185	INT253129	Ins1 Regulation of Phosphorylation of Akt1	3	0.11	1.66	0.17
186	INT176133	AKT1 Regulation of BCL2	2	0.12	1.84	0.17
187	INT179841	Il11 Regulation of Positive_regulation of Akt1	1	0.08	0.07	0.17
188	INT105334	PTGER1 Positive_regulation of Positive_regulation of AKT1	1	0.05	0.66	0.17
189	INT282858	Bpifa2 Negative_regulation of Akt1	1	0.05	0.91	0.17
190	INT176134	AKT1 Regulation of Gene_expression of BIRC3	1	0.08	1.09	0.17
191	INT179849	Il11 Regulation of Positive_regulation of Pdpk1	1	0.05	0.07	0.17
192	INT226209	Pik3cb Positive_regulation of Phosphorylation of Akt1	1	0.10	1.16	0.17
193	INT282861	Bpifa2 Negative_regulation of Phosphorylation of Akt1	1	0.05	0.91	0.17
194	INT161547	Trpv1 Regulation of Sorbs1	1	0.03	0.25	0.17
195	INT218937	Akt1 Positive_regulation of Parn	1	0.01	0.65	0.16
196	INT316484	Akt1 Positive_regulation of Positive_regulation of Stat3	1	0.01	0.87	0.16
197	INT343475	Epo Regulation of Akt1	1	0.18	0.41	0.16
198	INT178079	EDN1 Positive_regulation of Positive_regulation of AKT1	1	0.05	0.91	0.16
199	INT343478	Epo Regulation of Gene_expression of Akt1	1	0.40	0.41	0.16
200	INT218930	Akt1 Positive_regulation of Xiap	1	0.06	0.64	0.16

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of establishment of protein localization in plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of establishment of protein localization in plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT103924	Positive_regulation of Akt1	359	0.69	158.94	60.34
2	INT117713	Phosphorylation of Akt1	275	0.82	95.82	54.34
3	INT1232	Positive_regulation of Pdpk1	78	0.42	24.33	50.17
4	INT40777	Positive_regulation of Akt1	163	0.69	59.41	49.43
5	INT106525	Phosphorylation of Akt1	436	0.82	183.81	47.82
6	INT18992	Negative_regulation of Pdpk1	53	0.42	19.02	40.95
7	INT114881	Gene_expression of Akt1	227	0.78	102.49	31.81
8	INT112707	Negative_regulation of Akt1	89	0.59	28.85	27.76
9	INT122570	Negative_regulation of Akt1	173	0.59	91.44	25.53
10	INT40776	Gene_expression of Akt1	99	0.77	34.91	24.39
11	INT117718	Positive_regulation of Phosphorylation of Akt1	112	0.69	39.26	24.09
12	INT48769	Regulation of Pdpk1	20	0.35	9.78	20.36
13	INT89396	Phosphorylation of AKT1	225	0.82	111.66	19.61
14	INT86187	Positive_regulation of AKT1	199	0.69	122.13	19.44
15	INT97245	Gene_expression of AKT1	217	0.77	119.63	15.59
16	INT26733	Gene_expression of Pdpk1	17	0.48	5.74	13.91
17	INT109304	Positive_regulation of Phosphorylation of Akt1	113	0.69	40.92	13.49
18	INT74838	Positive_regulation of Sorbs1	18	0.34	6.93	12.63
19	INT89395	Negative_regulation of AKT1	127	0.58	70.27	12.54
20	INT8533	Regulation of Sorbs1	9	0.27	3.01	11.98
21	INT26534	Regulation of Akt1	34	0.61	14.47	11.86
22	INT5630	Localization of Pdpk1	10	0.45	5.21	11.36
23	INT75137	Regulation of Akt1	74	0.48	37.89	9.7
24	INT8535	Localization of Sorbs1	9	0.80	2.71	9.07
25	INT120967	Negative_regulation of Phosphorylation of Akt1	47	0.57	23.67	8.98
26	INT104396	Positive_regulation of Positive_regulation of Akt1	44	0.55	14.78	8.69
27	INT72539	Gene_expression of Sorbs1	10	0.78	4.98	8.14
28	INT104013	Negative_regulation of Gene_expression of Pdpk1	4	0.31	2.36	7.89
29	INT106522	Negative_regulation of Phosphorylation of Akt1	65	0.58	34.44	7.83
30	INT103925	Negative_regulation of Positive_regulation of Akt1	32	0.58	15.19	7.39
31	INT126748	Positive_regulation of Positive_regulation of Akt1	26	0.55	11.15	7.08
32	INT71824	Phosphorylation of Pdpk1	14	0.38	4.9	6.86
33	INT117721	Positive_regulation of Gene_expression of Akt1	22	0.69	6.26	6.08
34	INT114882	Positive_regulation of Gene_expression of Akt1	45	0.69	21.29	6.06
35	INT55077	Positive_regulation of Positive_regulation of Pdpk1	6	0.26	1.77	5.78
36	INT68465	Positive_regulation of Gene_expression of Pdpk1	7	0.19	2.35	5.49
37	INT105336	Regulation of AKT1	52	0.56	32.53	4.89
38	INT134657	Localization of Akt1	37	0.68	11.58	4.62
39	INT72538	Negative_regulation of Sorbs1	7	0.59	4.49	4.61
40	INT122569	Negative_regulation of Gene_expression of Akt1	34	0.54	17.15	4.44
41	INT109450	Positive_regulation of Phosphorylation of AKT1	62	0.64	25.18	4.21
42	INT75136	Binding of Akt1	27	0.27	8.81	4.15
43	INT1231	Negative_regulation of Positive_regulation of Pdpk1	6	0.35	1.88	4.13
44	INT139898	Negative_regulation of Positive_regulation of Akt1	15	0.42	4.66	4.06
45	INT132223	Negative_regulation of Negative_regulation of Akt1	6	0.42	2.75	3.66
46	INT136692	Localization of Akt1	12	0.78	2.14	3.65
47	INT8536	Binding of Sorbs1	2	0.14	1.24	3.64
48	INT157687	Regulation of Gene_expression of Akt1	9	0.62	4.96	3.27
49	INT108203	Negative_regulation of Gene_expression of AKT1	28	0.54	16.38	3.19
50	INT117720	Negative_regulation of Gene_expression of Akt1	11	0.37	2.33	3.08
51	INT89392	Negative_regulation of Positive_regulation of AKT1	23	0.50	15.69	3.02
52	INT89401	Negative_regulation of Phosphorylation of AKT1	68	0.58	35.61	2.8
53	INT117715	Regulation of Phosphorylation of Akt1	15	0.51	3.23	2.78
54	INT47846	Negative_regulation of Localization of Pdpk1	2	0.33	1.12	2.75
55	INT96763	Positive_regulation of Localization of Pdpk1	1	0.39	2.08	2.65
56	INT214355	Binding of Akt1	13	0.36	3.72	2.59
57	INT122060	Positive_regulation of Positive_regulation of Sorbs1	2	0.34	0.06	2.57
58	INT122424	Gene_expression of Prkci	1	0.58	0	2.56
59	INT118791	Binding of AKT1	32	0.48	15.51	2.25
60	INT138286	Regulation of Positive_regulation of Akt1	13	0.45	4.93	2.22
61	INT8537	Negative_regulation of Regulation of Sorbs1	1	0.18	0	2.17
62	INT101866	Positive_regulation of Gene_expression of AKT1	49	0.52	17.47	2.14
63	INT122423	Negative_regulation of Gene_expression of Prkci	1	0.43	0	2.04
64	INT26735	Regulation of Gene_expression of Pdpk1	2	0.24	0.56	1.84
65	INT123130	Positive_regulation of Positive_regulation of AKT1	22	0.49	11.77	1.83
66	INT142236	Regulation of Phosphorylation of Akt1	13	0.61	5.02	1.75
67	INT104014	Negative_regulation of Phosphorylation of Pdpk1	2	0.23	0.59	1.72
68	INT165332	Negative_regulation of Negative_regulation of Akt1	5	0.42	3.27	1.7
69	INT117714	Regulation of Positive_regulation of Akt1	3	0.61	0.44	1.61
70	INT67464	Positive_regulation of Negative_regulation of Pdpk1	1	0.19	0.15	1.41
71	INT118927	Positive_regulation of Phosphorylation of Pdpk1	2	0.04	0.76	1.38
72	INT180763	Positive_regulation of Binding of Sorbs1	1	0.02	1.25	1.26
73	INT180762	Negative_regulation of Binding of Sorbs1	1	0.02	1.24	1.26
74	INT221206	Phosphorylation of Pdpk1	3	0.53	0.13	1.25
75	INT167409	Regulation of Gene_expression of AKT1	8	0.56	4.86	1.23
76	INT104011	Transcription of Pdpk1	1	0.28	0	1.2
77	INT104012	Regulation of Transcription of Pdpk1	1	0.14	0	1.2
78	INT26734	Binding of Pdpk1	4	0.29	1.01	1.19
79	INT135556	Localization of AKT1	38	0.69	12.78	1.17
80	INT118792	Regulation of Positive_regulation of AKT1	8	0.61	3.73	1.15
81	INT176147	Regulation of Phosphorylation of AKT1	14	0.41	6.41	1.13
82	INT207203	Transcription of Akt1	6	0.67	3.73	1.1
83	INT191050	Positive_regulation of Negative_regulation of Akt1	6	0.31	1.82	1.03
84	INT122421	Phosphorylation of Prkci	1	0.47	0	1.02
85	INT68467	Regulation of Regulation of Pdpk1	1	0.05	0.09	0.96
86	INT134660	Positive_regulation of Localization of Akt1	10	0.32	6.33	0.94
87	INT162167	Negative_regulation of Gene_expression of ARF6	1	0.38	0	0.94
88	INT163508	Regulation of Gene_expression of Akt1	3	0.45	1.65	0.92
89	INT162168	Gene_expression of ARF6	1	0.68	0	0.92
90	INT266561	Negative_regulation of Positive_regulation of Sorbs1	1	0.01	1.01	0.88
91	INT151170	Regulation of Regulation of Akt1	2	0.45	3.28	0.73
92	INT153565	Gene_expression of PRKCI	1	0.75	0	0.72
93	INT299338	Negative_regulation of Regulation of AKT1	2	0.31	2.32	0.68
94	INT207204	Regulation of Transcription of Akt1	3	0.35	1.41	0.66
95	INT166024	Protein_catabolism of AKT1	5	0.46	2.6	0.64
96	INT281466	Negative_regulation of Regulation of Akt1	1	0.33	0.31	0.63
97	INT153568	Binding of PRKCI	1	0.36	0	0.6
98	INT123131	Negative_regulation of Negative_regulation of AKT1	6	0.42	3.23	0.58
99	INT122420	Regulation of Prkci	1	0.44	0	0.58
100	INT79249	Regulation of Negative_regulation of Pdpk1	1	0.03	0.09	0.57
101	INT218900	Regulation of Negative_regulation of Akt1	3	0.15	1.73	0.53
102	INT98037	Negative_regulation of Negative_regulation of Pdpk1	1	0.05	0.26	0.52
103	INT276189	Regulation of Localization of Akt1	1	0.43	0.2	0.5
104	INT323479	Phosphorylation of Sorbs1	1	0.06	1.8	0.49
105	INT30080	Binding of Arhgef16	1	0.11	0.54	0.45
106	INT34037	Regulation of Arhgef16	1	0.15	0.6	0.45
107	INT235660	Gene_expression of EPHA2	27	0.75	23.46	0.4
108	INT102722	Phosphorylation of PDPK1	3	0.82	1.39	0.4
109	INT236107	Binding of Pdpk1	2	0.26	1.38	0.39
110	INT236105	Negative_regulation of Binding of Pdpk1	1	0.30	1.22	0.39
111	INT254484	Positive_regulation of Gene_expression of Sorbs1	4	0.12	1.9	0.37
112	INT235655	Positive_regulation of Gene_expression of EPHA2	14	0.67	13.48	0.35
113	INT179816	Positive_regulation of Pdpk1	4	0.31	0.36	0.35
114	INT235658	Positive_regulation of EPHA2	4	0.67	3.42	0.32
115	INT321348	Positive_regulation of Localization of Akt1	1	0.30	0.08	0.32
116	INT238439	Positive_regulation of PDPK1	2	0.20	1.3	0.31
117	INT239464	Regulation of Negative_regulation of Akt1	3	0.31	0.37	0.25
118	INT102717	Gene_expression of PDPK1	1	0.77	3.11	0.25
119	INT102719	Negative_regulation of PDPK1	1	0.58	3	0.21
120	INT200666	Transcription of AKT1	8	0.66	4.23	0.2
121	INT230483	Protein_catabolism of Akt1	2	0.10	1.11	0.2
122	INT352913	Regulation of EPHA2	1	0.05	0.74	0.2
123	INT276192	Transcription of Akt1	1	0.66	0.47	0.18
124	INT176153	Regulation of Negative_regulation of AKT1	3	0.39	2.13	0.16
125	INT135557	Positive_regulation of Localization of AKT1	3	0.46	0.49	0.15
126	INT226185	Protein_catabolism of Akt1	7	0.53	2.43	0.14
127	INT302248	Negative_regulation of Binding of AKT1	2	0.25	1	0.14
128	INT285902	Positive_regulation of Transcription of AKT1	1	0.06	0.6	0.13
129	INT102720	Positive_regulation of Gene_expression of PDPK1	1	0.69	1.61	0.13
130	INT214360	Negative_regulation of Binding of Akt1	2	0.41	0.09	0.12
131	INT236109	Localization of Pdpk1	1	0.49	0.75	0.12
132	INT355216	Positive_regulation of Binding of Akt1	1	0.37	0.35	0.12
133	INT199082	Positive_regulation of Binding of Akt1	4	0.17	1.25	0.11
134	INT192239	Positive_regulation of Binding of AKT1	2	0.26	0.91	0.08
135	INT102718	Negative_regulation of Phosphorylation of PDPK1	1	0.43	0.83	0.08
136	INT302629	Positive_regulation of Rhog	1	0.33	0.07	0.07
137	INT104656	Regulation of Phosphorylation of Pdpk1	1	0.05	1.74	0.07
138	INT307475	Positive_regulation of Negative_regulation of Akt1	1	0.12	0.12	0.07
139	INT243988	Binding of Nrxn1	1	0.01	0.21	0.07
140	INT182302	Negative_regulation of Localization of AKT1	5	0.39	3.52	0.06
141	INT120564	Gene_expression of Pdpk1	2	0.62	1.54	0.06
142	INT209184	Regulation of PRKCI	1	0.02	0.06	0.06
143	INT243932	Gene_expression of Nrxn1	1	0.02	0.28	0.06
144	INT120565	Positive_regulation of Gene_expression of Pdpk1	1	0.40	1.26	0.06
145	INT302628	Gene_expression of Rhog	1	0.45	0.2	0.05
146	INT236706	Regulation of Pdpk1	1	0.12	0.38	0.04
147	INT300989	Positive_regulation of Negative_regulation of AKT1	2	0.41	1.27	0.03
148	INT288183	Positive_regulation of Regulation of Akt1	1	0.05	0.06	0.03
149	INT336399	Transcription of EPHA2	1	0.24	2.21	0.03
150	INT235654	Binding of EPHA2	5	0.36	4.26	0
151	INT268244	Negative_regulation of Localization of Akt1	2	0.28	2	0
152	INT173193	Binding of SORBS1	2	0.14	1.29	0
153	INT293479	Positive_regulation of Protein_catabolism of Akt1	1	0.26	0.53	0
154	INT331203	Positive_regulation of Binding of Pdpk1	1	0.15	0.17	0
155	INT273545	Negative_regulation of Epha2	1	0.28	0.08	0
156	INT340543	Regulation of Binding of Akt1	1	0.23	0.18	0
157	INT230480	Positive_regulation of Protein_catabolism of Akt1	1	0.06	0.75	0
158	INT198028	Regulation of Regulation of AKT1	1	0.22	1.08	0
159	INT189989	Negative_regulation of Pdpk1	1	0.08	1.48	0
160	INT223603	Regulation of Localization of AKT1	1	0.23	0.65	0
161	INT339743	Positive_regulation of SORBS1	1	0.06	0.39	0
162	INT235652	Localization of EPHA2	1	0.72	0.89	0
163	INT300629	Transcription of Epha2	1	0.22	1.11	0
164	INT200688	Negative_regulation of Transcription of AKT1	1	0.54	1.53	0