GO:2000251

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Name positive regulation of actin cytoskeleton reorganization
Categary Process
Go Slim No
Go Link GO:2000251
Unique Molecular Interactions 39
Total Molecular Interactions 53
Total Single Events 231
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of actin cytoskeleton reorganization. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of actin cytoskeleton reorganization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221630 Binding of Fes and Plxna1 1 0.01 1.02 0.5
2 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48
3 INT181896 TNF Regulation of TEK 1 0.03 1.21 0.33
4 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22
5 INT303029 Binding of TEK and Angpt1 1 0.26 1.82 0.22
6 INT221642 Binding of Fes and Fer 1 0.32 0.27 0.2
7 INT221641 Binding of Dpysl2 and Fes 1 0.23 0.27 0.2
8 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
9 INT221632 Plxna1 Negative_regulation of Fes 1 0.02 0.58 0.15
10 INT221662 Fes Positive_regulation of Phosphorylation of Dpysl2 1 0.24 0.14 0.14
11 INT221615 Dpysl2 Positive_regulation of Gene_expression of Fes 1 0.21 0.14 0.13
12 INT221620 Fes Regulation of Gh 1 0.01 0.39 0.12
13 INT221634 Fes Regulation of Ngf 1 0.28 0.33 0.12
14 INT221659 Binding of Fes and Dpysl5 1 0.16 0.58 0.11
15 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1
16 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1
17 INT221954 Binding of CDK5 and CDK5R2 1 0.02 0.36 0.09
18 INT221655 Plxna1 Negative_regulation of Phosphorylation of Fes 1 0.02 0.17 0.08
19 INT221631 Dpysl2 Negative_regulation of Fes 1 0.21 0.42 0.07
20 INT298699 Kdr Regulation of Tek 1 0.11 0.28 0.06
21 INT298701 Manea Regulation of Tek 1 0.03 0.28 0.06
22 INT221663 Fes Positive_regulation of Binding of Plxna1 1 0.02 0.4 0.05
23 INT221654 Fes Positive_regulation of Phosphorylation of Crmp1 1 0.18 0.37 0.04
24 INT178501 Angpt1 Positive_regulation of Tek 1 0.06 0.78 0.04
25 INT298703 Angpt1 Regulation of Tek 1 0.12 0.27 0.03
26 INT219352 CDK5 Negative_regulation of PAK1 1 0.22 0.72 0.03
27 INT221623 Fyn Regulation of Fes 1 0.14 0.2 0.03
28 INT200812 Akt1 Positive_regulation of Negative_regulation of Hck 1 0.25 1.02 0
29 INT298702 Tek Regulation of Kdr 1 0.03 0.33 0
30 INT268887 Binding of ANGPT1 and Tek 1 0.10 0 0
31 INT176096 Regulation of Binding of Angpt1 and Tek 1 0.07 0.54 0
32 INT176097 Binding of Angpt1 and Tek 1 0.06 0.48 0
33 INT333560 NOS3 Regulation of HCK 1 0.01 0.2 0
34 INT347226 Hck Regulation of Gene_expression of Lyn 1 0.10 0.08 0
35 INT347225 Hck Regulation of Positive_regulation of Bcr 1 0.15 0.07 0
36 INT221622 Dpysl2 Positive_regulation of Fes 1 0.24 0 0
37 INT298704 Tek Regulation of Manea 1 0.02 0.33 0
38 INT221635 Dpysl2 Negative_regulation of Phosphorylation of Fes 1 0.20 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of actin cytoskeleton reorganization. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of actin cytoskeleton reorganization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19
2 INT153719 Gene_expression of TEK 10 0.49 9.82 1.88
3 INT221560 Gene_expression of Fes 36 0.72 6.63 1.51
4 INT127452 Positive_regulation of CDK5 5 0.32 1.88 0.87
5 INT221543 Binding of Fes 1 0.45 1.79 0.83
6 INT219358 Gene_expression of CDK5 9 0.58 5.65 0.81
7 INT221557 Phosphorylation of Fes 1 0.76 2.49 0.76
8 INT145932 Gene_expression of Hck 5 0.77 2.69 0.73
9 INT90181 Binding of Hck 2 0.36 0.08 0.49
10 INT176085 Regulation of Tek 6 0.37 3.36 0.4
11 INT176079 Positive_regulation of Tek 6 0.41 3.15 0.36
12 INT221973 Negative_regulation of CDK5 4 0.57 2.26 0.36
13 INT254367 Transcription of TEK 1 0.14 1.08 0.36
14 INT181921 Binding of TEK 2 0.09 1.88 0.32
15 INT254372 Negative_regulation of TEK 1 0.12 1.05 0.31
16 INT181788 Positive_regulation of Gene_expression of TEK 1 0.27 1.26 0.2
17 INT219375 Localization of CDK5 4 0.52 2.8 0.19
18 INT178481 Binding of Tek 2 0.28 1.55 0.19
19 INT221535 Regulation of Fes 1 0.25 0.19 0.19
20 INT221549 Localization of Fes 1 0.70 0.66 0.19
21 INT221532 Positive_regulation of Fes 1 0.47 0.59 0.19
22 INT221974 Phosphorylation of CDK5 1 0.56 0.99 0.19
23 INT176091 Regulation of Positive_regulation of Tek 1 0.37 0.22 0.18
24 INT221972 Regulation of CDK5 1 0.42 1.87 0.16
25 INT298697 Negative_regulation of Tek 2 0.35 0.85 0.14
26 INT221571 Negative_regulation of Fes 1 0.55 0.56 0.12
27 INT221577 Negative_regulation of Phosphorylation of Fes 1 0.40 0.37 0.12
28 INT226281 Regulation of TEK 1 0.60 1.33 0.11
29 INT341559 Positive_regulation of Gene_expression of CDK5 1 0.23 0.25 0.11
30 INT221530 Negative_regulation of Binding of Fes 1 0.40 0.17 0.08
31 INT341567 Negative_regulation of Gene_expression of CDK5 1 0.27 0.24 0.07
32 INT219355 Binding of CDK5 3 0.35 2.02 0.06
33 INT178495 Negative_regulation of Positive_regulation of Tek 1 0.14 1.05 0.06
34 INT200861 Negative_regulation of Binding of Tek 1 0.32 0.3 0.06
35 INT178484 Positive_regulation of Phosphorylation of Tek 1 0.23 0.79 0.04
36 INT178486 Phosphorylation of Tek 1 0.27 0.73 0.04
37 INT221565 Regulation of Binding of Fes 1 0.42 0.05 0.03
38 INT312928 Localization of Tek 1 0.31 0.66 0.03
39 INT200789 Negative_regulation of Hck 1 0.53 1.01 0
40 INT312931 Negative_regulation of Regulation of Tek 1 0.19 0.23 0
41 INT218765 Regulation of Localization of TEK 1 0.02 0.87 0
42 INT221567 Transcription of Fes 1 0.64 0 0
43 INT200860 Transcription of Tek 1 0.39 0.26 0
44 INT333612 Phosphorylation of HCK 1 0.17 0.17 0
45 INT218764 Localization of TEK 1 0.04 0.87 0
46 INT221563 Positive_regulation of Localization of Fes 1 0.47 0.05 0
47 INT243005 Positive_regulation of Positive_regulation of Tek 1 0.10 0.98 0
48 INT221524 Regulation of Localization of Fes 1 0.42 0.06 0
49 INT221523 Negative_regulation of Gene_expression of Fes 1 0.40 0 0
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