GOS:cell proliferation

This page displays the top molecular interactions and top single events that were mentioned in the literature for cell proliferation. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported for cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Disease Relevance	TM Confidence	Documents	Genes linked to cell proliferation	Pain Relevance
1	INT206768	TP53 Positive_regulation of Ltp	5.83	0.01	2	1	10.21
2	INT259228	Binding of Oprm1 and Glul	0.08	0.00	1	1	7.22
3	INT254001	Binding of Cxcr4 and Mif	14.17	0.52	1	1	7.18
4	INT170447	Binding of Pax3 and Spr	0.1	0.01	1	1	5.37
5	INT126335	Binding of Pax3 and Tac1	6.22	0.07	6	1	5.27
6	INT180774	Gdnf Positive_regulation of Trpv1	2.43	0.33	1	1	4.37
7	INT259209	Binding of Glul and Flna	0	0.03	1	1	4.2
8	INT146412	Tnf Positive_regulation of Gene_expression of Trpv1	5.22	0.66	2	1	3.22
9	INT140024	Tnf Positive_regulation of Gene_expression of Il1b	2.75	0.49	2	1	2.61
10	INT253988	Binding of Cd74 and Mif	6.57	0.36	1	4	2.52
11	INT356289	Binding of Egfr and Egf	3.02	0.13	1	1	2.52
12	INT151826	Tnf Positive_regulation of TNF	3.38	0.04	1	1	2.51
13	INT122775	Gdnf Regulation of Gene_expression of Trpv1	2.72	0.59	4	1	2.42
14	INT61733	Tlr4 Positive_regulation of Gene_expression of Tnf	1.99	0.26	3	1	2.36
15	INT106750	Pes1 Negative_regulation of Positive_regulation of Casp3	0	0.23	3	2	2.35
16	INT106753	Pes1 Negative_regulation of Gene_expression of Casp3	0	0.12	2	2	2.19
17	INT273120	NOVA2 Regulation of Gene_expression of MET	1.17	0.23	1	1	2.11
18	INT190524	Ros1 Positive_regulation of Nfkb1	4.24	0.02	3	1	2.06
19	INT115042	Gdnf Regulation of Calca	0.25	0.53	1	1	2.03
20	INT140032	Tnf Positive_regulation of Gene_expression of Ifng	2.23	0.43	2	1	2
21	INT140026	Il1b Positive_regulation of Gene_expression of Tnf	2.23	0.49	2	1	2
22	INT213973	Binding of Pax3 and Mthfd1	0.16	0.00	1	1	1.99
23	INT281381	FSCN1 Positive_regulation of Gene_expression of Gfap	1.13	0.06	1	1	1.98
24	INT163266	Crh Negative_regulation of Tyr	0.45	0.01	1	2	1.98
25	INT129212	RYBP Positive_regulation of Tnf	1.9	0.03	2	1	1.95
26	INT169570	Binding of ROS1 and TRPV1	3.07	0.33	3	1	1.89
27	INT135582	Prok2 Positive_regulation of Localization of Prkce	1.02	0.06	1	2	1.87
28	INT349588	Aap Positive_regulation of Gene_expression of Ros1	0.73	0.06	1	2	1.85
29	INT169468	Binding of Egfr and Spink3	3.73	0.37	1	1	1.83
30	INT122966	FSCN1 Positive_regulation of FSCN1 Positive_regulation of Bdnf	1.14	0.02	1	1	1.79
31	INT122964	FSCN1 Positive_regulation of Bdnf	1.14	0.01	1	1	1.79
32	INT203149	Binding of Mif and Osm	2.93	0.02	1	1	1.78
33	INT346217	Braf Positive_regulation of Phosphorylation of Map2k1	3.23	0.22	1	1	1.72
34	INT175986	Ros1 Positive_regulation of Gtf3a	4.75	0.01	2	1	1.71
35	INT169464	Akt1 Positive_regulation of Egfr	1.63	0.28	1	1	1.7
36	INT167427	Mapk8 Regulation of Regulation of Tnf	2.83	0.26	1	1	1.7
37	INT150232	Samhd1 Positive_regulation of Gene_expression of TNFSF13B	1.74	0.01	1	1	1.67
38	INT86637	POMC Regulation of Gene_expression of KRT16	1.22	0.47	2	1	1.61
39	INT180812	Gdnf Positive_regulation of Gene_expression of Sorbs1	0.83	0.02	1	1	1.61
40	INT180811	Gdnf Positive_regulation of Regulation of Sorbs1	0.83	0.01	1	1	1.61
41	INT130839	Gfap Positive_regulation of S100B	1.9	0.51	1	1	1.56
42	INT198653	TNF Positive_regulation of MIF	3.81	0.15	1	1	1.55
43	INT106751	Pes1 Negative_regulation of Casp3	0	0.23	2	2	1.54
44	INT249498	Src Positive_regulation of Phosphorylation of Grin2b	1.11	0.22	1	1	1.54
45	INT140029	Ifng Positive_regulation of Gene_expression of Tnf	1.69	0.43	1	1	1.5
46	INT156008	Bcl2 Regulation of Localization of Aifm1	1.92	0.17	1	1	1.47
47	INT276687	Pax3 Positive_regulation of Nkx1-1	0.59	0.00	1	1	1.47
48	INT180791	Negative_regulation of Gdnf Regulation of Calca	0	0.17	1	1	1.47
49	INT104972	MITF Regulation of Transcription of TYR	0.35	0.20	1	1	1.45
50	INT221242	Ros1 Positive_regulation of Prkca	0.39	0.02	1	1	1.44
51	INT180790	Gdnf Regulation of Localization of Trpv1	1.21	0.15	1	1	1.43
52	INT224404	Binding of GYPC and PYY	1.48	0.04	1	1	1.42
53	INT202910	Uchl1 Positive_regulation of Gene_expression of Tacr1	1.65	0.05	1	2	1.42
54	INT116827	Binding of UCHL1 and TRPV1	0.88	0.41	1	1	1.39
55	INT117871	Sct Positive_regulation of Pes1	0	0.10	1	2	1.36
56	INT83197	Binding of Ntrk1 and Gdnf	1.05	0.01	1	1	1.36
57	INT161513	Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf	0.27	0.33	1	1	1.35
58	INT145930	ecs Positive_regulation of Gene_expression of Bcl2	2.06	0.01	1	1	1.34
59	INT180802	Gdnf Positive_regulation of Sorbs1	0.98	0.02	1	1	1.34
60	INT281382	FSCN1 Positive_regulation of Sds	0.84	0.02	1	1	1.33
61	INT180764	Calca Regulation of Positive_regulation of Gdnf	0	0.21	1	1	1.32
62	INT242605	Gdnf Positive_regulation of Trpv1	0.17	0.26	1	1	1.3
63	INT169297	TRPV1 Positive_regulation of EGFR	0.37	0.64	1	1	1.3
64	INT158144	Binding of Gpx1 and Glyat	0	0.31	2	1	1.29
65	INT130333	FUT3 Negative_regulation of Positive_regulation of Tnf	0.36	0.01	1	1	1.29
66	INT86636	POMC Positive_regulation of Gene_expression of KRT16	0.83	0.39	2	1	1.28
67	INT114929	Positive_regulation of Binding of Oprm1 and Crebbp	0.14	0.06	1	1	1.28
68	INT114925	Binding of Oprm1 and Crebbp	0.14	0.06	1	1	1.27
69	INT87026	ZAK Positive_regulation of Gene_expression of IL12A	2.55	0.12	3	1	1.26
70	INT84886	APC Regulation of PPARD	1.57	0.51	1	2	1.26
71	INT30128	Binding of MET and Gast	0.18	0.06	1	1	1.25
72	INT317569	Prkca Positive_regulation of Phosphorylation of Src	0	0.11	1	1	1.25
73	INT249487	Binding of Ephb1 and Src	0.74	0.17	1	1	1.23
74	INT52955	Binding of Slc6a3 and Pdpn	1.11	0.17	1	2	1.22
75	INT253999	Binding of Cxcl12 and Mif	2.26	0.41	1	1	1.22
76	INT281383	FSCN1 Positive_regulation of Fig4	0.44	0.02	1	1	1.19
77	INT281379	Tcf21 Regulation of FSCN1	0.66	0.01	1	1	1.19
78	INT180814	Binding of Ret and Gdnf	1.31	0.01	1	1	1.17
79	INT353338	F2r Positive_regulation of Localization of Mif	1.25	0.68	1	1	1.16
80	INT189017	Binding of Pax3 and Lmna	0.42	0.14	1	1	1.16
81	INT19535	Binding of ADRA1D and ALB	0.8	0.42	3	1	1.15
82	INT314206	Mapk14 Positive_regulation of Pax3	0.67	0.08	1	1	1.15
83	INT242625	Gdnf Positive_regulation of Pax3	0.34	0.01	1	2	1.15
84	INT125284	FSCN1 Positive_regulation of Positive_regulation of EPHB2	0.4	0.04	1	1	1.14
85	INT294911	Pax3 Positive_regulation of Il6	1.78	0.06	1	1	1.14
86	INT225104	CNR1 Positive_regulation of Gene_expression of RETNLB	1.41	0.01	1	1	1.14
87	INT289659	Tnfrsf1b Negative_regulation of Mcpt3	0.82	0.02	1	1	1.13
88	INT332776	FSCN1 Positive_regulation of Grin1	0.21	0.02	1	1	1.12
89	INT108547	AKT1 Regulation of MAPKAPK5	1.2	0.04	1	1	1.08
90	INT79094	PDYN Positive_regulation of PRL	0.09	0.35	1	1	1.07
91	INT263048	Tgfb1 Positive_regulation of Gene_expression of Mmp2	0.81	0.13	1	1	1.07
92	INT297491	Positive_regulation of Lta Positive_regulation of Ltp	0.16	0.00	1	1	1.06
93	INT73311	Binding of Oprm1 and Pdpn	0.71	0.08	1	2	1.06
94	INT243494	Binding of Vta1 and LOC308670	0.06	0.01	1	1	1.06
95	INT8410	IL1A Positive_regulation of Vip	0.68	0.02	1	1	1.05
96	INT335401	Hgf Positive_regulation of Ngf	1.13	0.30	1	2	1.04
97	INT117908	Em Regulation of Localization of Pax3	0.07	0.00	1	1	1.03
98	INT118859	GNA14 Positive_regulation of STAT3	0.38	0.01	1	1	1.03
99	INT87025	ZAK Positive_regulation of Gene_expression of IL6	1.59	0.11	2	1	1.02
100	INT49164	Binding of Pax3 and Nka1	0.37	0.01	1	1	1.01
101	INT33135	Binding of NFKBIL1 and PRL	0.29	0.09	1	1	1.01
102	INT25155	TRH Positive_regulation of PRL	0.4	0.50	2	1	1
103	INT317518	Src Regulation of Negative_regulation of Oprm1	0.07	0.16	1	1	1
104	INT142202	FL Positive_regulation of Bcl2	0.39	0.05	1	1	0.99
105	INT170449	Pax3 Positive_regulation of Spr	0.26	0.01	1	1	0.99
106	INT143915	Src Regulation of Rbm39	0.18	0.03	1	1	0.99
107	INT180770	Gdnf Positive_regulation of Zbtb38	0.27	0.00	1	1	0.99
108	INT129216	Negative_regulation of RYBP Positive_regulation of Tnf	1.24	0.01	1	1	0.98
109	INT147504	Binding of Ncam1 and Gdnf	0.87	0.31	1	1	0.98
110	INT41659	IL31RA Regulation of PRL	1.07	0.22	1	1	0.98
111	INT49163	Binding of Pax3 and Calca	0.37	0.03	1	1	0.98
112	INT4916	Binding of Pax3 and Wdyhv1	0	0.00	1	1	0.98
113	INT54972	Binding of EDNRA and EDNRB	3.31	0.52	7	1	0.97
114	INT133616	Map2k1 Regulation of Fadd	0.29	0.04	1	1	0.97
115	INT133614	Map2k1 Regulation of Daxx	0.29	0.02	1	1	0.97
116	INT133615	Regulation of Map2k1 Regulation of Fadd	0.29	0.04	1	1	0.97
117	INT86960	ADRA1D Negative_regulation of Prl	0	0.00	1	1	0.97
118	INT119276	Negative_regulation of CYBB Negative_regulation of Positive_regulation of ROS1	1.18	0.09	1	1	0.97
119	INT137919	Binding of Oprm1 and Stat3	0	0.30	1	1	0.97
120	INT121744	Src Positive_regulation of Positive_regulation of Ephb1	0	0.35	1	1	0.96
121	INT73461	PTPLA Positive_regulation of Transcription of TP53	0.99	0.06	1	1	0.96
122	INT180780	Ngf Regulation of Gdnf	0.28	0.22	1	1	0.96
123	INT281380	Fos Negative_regulation of Gene_expression of FSCN1	0.4	0.07	1	1	0.96
124	INT182203	Binding of CXCL1 and CXCR2	1.25	0.14	1	1	0.95
125	INT107951	Pax3 Positive_regulation of Tac1	1.21	0.11	1	1	0.95
126	INT163265	Sst Negative_regulation of Tyr	0.22	0.00	1	2	0.95
127	INT180803	Sorbs1 Regulation of Gdnf	0.28	0.01	1	1	0.95
128	INT73466	PTPLA Positive_regulation of Transcription of Hras1	0.98	0.21	1	1	0.95
129	INT199396	Prok2 Regulation of Trpv1	1.23	0.43	1	1	0.94
130	INT232426	HRH2 Regulation of Localization of PRL	0.38	0.15	1	1	0.94
131	INT182199	Binding of CXCR5 and CXCL1	1.24	0.16	1	1	0.94
132	INT129211	RYBP Positive_regulation of Gene_expression of Tnf	1.04	0.01	1	1	0.94
133	INT330629	TP53 Negative_regulation of Gene_expression of Fos	1.76	0.30	1	1	0.94
134	INT281377	FSCN1 Positive_regulation of Gene_expression of Fos	0.49	0.08	1	1	0.93
135	INT182189	Binding of CXCL1 and CXCL13	1.24	0.14	1	1	0.93
136	INT122269	Src Negative_regulation of Positive_regulation of Grin2b	0.44	0.27	1	1	0.92
137	INT147505	Binding of Ret and Gdnf	0.81	0.27	1	1	0.92
138	INT161455	Mmp7 Positive_regulation of Egfr	0.19	0.03	1	1	0.92
139	INT112765	Binding of Nfkb1 and Bcl2	1.37	0.00	1	1	0.91
140	INT135446	Map2k1 Positive_regulation of Mapk3	0.25	0.54	1	1	0.91
141	INT165280	Tnf Positive_regulation of Gene_expression of Nos2	1.02	0.24	1	1	0.91
142	INT334529	Pax3 Positive_regulation of Gene_expression of Ngf	0.31	0.03	1	1	0.91
143	INT169469	Binding of Egfr and Tgfa	1.87	0.19	1	1	0.91
144	INT53152	Rac1 Regulation of Scg2	0	0.03	1	1	0.9
145	INT199393	Prok2 Positive_regulation of Prokr1	1.3	0.48	1	1	0.9
146	INT40636	Mif Negative_regulation of Pomc	0.07	0.25	1	1	0.9
147	INT35160	GH1 Regulation of PRL	0	0.37	2	1	0.89
148	INT134454	EGF Positive_regulation of EGFR	1.32	0.56	3	1	0.88
149	INT199189	Binding of Aldh2 and Ros1	0.3	0.06	1	1	0.88
150	INT167466	Ccdc80 Negative_regulation of Tnf	0.76	0.01	1	1	0.88
151	INT242621	Gdnf Positive_regulation of Gene_expression of Scn11a	0.12	0.05	1	1	0.88
152	INT134453	Negative_regulation of EGF Positive_regulation of EGFR	0.35	0.35	1	1	0.88
153	INT149559	Tgfb1 Positive_regulation of Gene_expression of Ccr5	0	0.00	1	2	0.88
154	INT134311	Tnf Positive_regulation of Protein_catabolism of Nfkbia	0.57	0.18	1	1	0.88
155	INT253992	Cxcl12 Positive_regulation of Mif	1.31	0.46	1	1	0.88
156	INT149562	Tgfb1 Positive_regulation of CXCL10	0	0.00	1	2	0.88
157	INT14626	Binding of Dpep1 and Pax3	0	0.01	1	1	0.87
158	INT203148	Mif Positive_regulation of Gene_expression of S100a8	1.56	0.00	1	1	0.87
159	INT185329	Pax3 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy	0.22	0.00	1	1	0.87
160	INT213977	Pax3 Negative_regulation of Gene_expression of Il2	0.25	0.00	1	1	0.86
161	INT166634	Binding of Bcl2 and Becn1	0.5	0.20	1	1	0.86
162	INT114324	RAF1 Positive_regulation of Phosphorylation of ADCY6	0.05	0.02	1	1	0.85
163	INT114323	Binding of ADCY6 and RAF1	0.05	0.02	1	1	0.85
164	INT128702	Ednra Regulation of EDNRA	0.58	0.00	1	1	0.84
165	INT106457	SPOP Positive_regulation of Negative_regulation of ADRA1D	0.56	0.02	1	1	0.84
166	INT97057	Bcl2l1 Regulation of Gene_expression of Trp53	0.51	0.36	1	1	0.83
167	INT149561	Tgfb1 Positive_regulation of Gene_expression of CCL2	0	0.00	1	2	0.83
168	INT46085	Binding of MET and Penk	0.06	0.02	1	1	0.83
169	INT149626	Il1b Regulation of Gene_expression of Tnf	0.83	0.41	1	1	0.83
170	INT102201	Tnf Regulation of Il1b	2.57	0.39	3	1	0.82
171	INT149558	Tgfb1 Positive_regulation of Gene_expression of Cxcr4	0	0.00	1	2	0.82
172	INT317513	Oprm1 Regulation of Positive_regulation of Src	0.4	0.09	1	1	0.82
173	INT317570	Oprm1 Regulation of Src	0.4	0.04	1	1	0.82
174	INT320120	MTX1 Positive_regulation of PTEN	0.09	0.04	1	1	0.82
175	INT322266	Binding of LIG4 and NOS3	2.35	0.02	1	1	0.82
176	INT117341	ADAM17 Positive_regulation of EGFR	3.56	0.16	1	1	0.82
177	INT122728	Pes1 Positive_regulation of Transcription of Penk	0	0.07	1	2	0.81
178	INT122727	Pes1 Positive_regulation of Penk	0	0.07	1	2	0.81
179	INT164607	Positive_regulation of GSR Positive_regulation of Gpx1	0.33	0.01	1	1	0.81
180	INT103331	Ngf Positive_regulation of Gdnf	0.57	0.01	1	1	0.8
181	INT164606	GSR Positive_regulation of Gpx1	0.32	0.01	1	1	0.8
182	INT322397	Egfr Positive_regulation of Adarb1	0.08	0.00	1	1	0.8
183	INT141605	Gene_expression of Ctsl Positive_regulation of Positive_regulation of MET	0	0.34	1	1	0.8
184	INT306271	IL1A Positive_regulation of Gene_expression of IL6	0.85	0.30	1	1	0.8
185	INT126555	Binding of Ighg1 and Tnf	2.2	0.35	1	1	0.8
186	INT274785	S100B Positive_regulation of Ngf	0.61	0.05	1	1	0.8
187	INT104831	Binding of GLI2 and NFKB1	0	0.08	1	1	0.8
188	INT180793	Binding of Bdnf and Gdnf Positive_regulation of Sorbs1	0.77	0.01	1	1	0.79
189	INT107917	RETNLB Positive_regulation of Gene_expression of App	1.2	0.01	1	1	0.79
190	INT2000	ASNA1 Positive_regulation of Localization of PRL	0	0.07	1	1	0.79
191	INT188531	Binding of TNF and PDXK	1.99	0.03	1	1	0.78
192	INT16491	Binding of ADRA1D and Serpinf2	0.78	0.02	1	1	0.78
193	INT184116	Il10 Positive_regulation of Stat3	1.15	0.18	2	1	0.77
194	INT103334	Gdnf Regulation of Gene_expression of TRPV1	0.53	0.02	1	1	0.77
195	INT103333	Gdnf Regulation of TRPV1	0.53	0.02	1	1	0.77
196	INT180496	Binding of CTS and PDXK	0.69	0.04	1	1	0.77
197	INT118854	GNA14 Positive_regulation of Positive_regulation of STAT3	0.31	0.02	1	1	0.76
198	INT49585	Binding of Glul and Selenbp2	0.19	0.20	1	1	0.76
199	INT134051	Jak2 Positive_regulation of Stat3	0.22	0.44	1	2	0.76
200	INT161945	TGFB2 Positive_regulation of TGFBR1	0.99	0.08	1	1	0.76

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported in cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Disease Relevance	TM Confidence	Documents	Pain Relevance
1	INT6488	Gene_expression of Tnf	339.61	0.78	484	191.58
2	INT915	Positive_regulation of PRL	141.96	0.70	342	104.31
3	INT8534	Localization of Pax3	28.71	0.59	85	82.82
4	INT14624	Gene_expression of Pax3	33.22	0.38	100	69.47
5	INT6489	Positive_regulation of Gene_expression of Tnf	92.31	0.70	140	67.85
6	INT6486	Positive_regulation of Tnf	123.47	0.70	168	66.05
7	INT253	Regulation of PRL	47.27	0.62	184	65.79
8	INT55344	Gene_expression of Ros1	217.64	0.54	396	59.98
9	INT1579	Gene_expression of PRL	119.2	0.78	279	55.41
10	INT82650	Gene_expression of Bcl2	211.71	0.78	312	55.03
11	INT66029	Negative_regulation of Tnf	84.28	0.59	100	48.16
12	INT55670	Negative_regulation of Gene_expression of Tnf	57.16	0.59	83	46.33
13	INT4913	Binding of Pax3	9.57	0.28	52	42.67
14	INT918	Positive_regulation of Localization of PRL	23.97	0.70	90	40.3
15	INT65889	Gene_expression of RETNLB	60.98	0.34	73	38.3
16	INT916	Regulation of Localization of PRL	22.98	0.62	92	38.13
17	INT77307	Gene_expression of Bcl2	319.77	0.77	399	38
18	INT74563	Positive_regulation of Gene_expression of ROS1	168.18	0.61	258	34.08
19	INT14823	Gene_expression of MET	51.92	0.75	103	32.48
20	INT35406	Localization of Tnf	64.63	0.81	94	31.65
21	INT48890	Gene_expression of Gdnf	28.62	0.77	91	31.49
22	INT10285	Binding of ADRA1D	25.82	0.47	102	31.11
23	INT19396	Regulation of Rac1	37.41	0.53	66	30.01
24	INT28361	Gene_expression of TP53	384.86	0.78	443	28.8
25	INT116737	Localization of Mif	52.97	0.81	63	28.11
26	INT52722	Localization of RETNLB	48.63	0.38	54	27.98
27	INT133876	Positive_regulation of Gene_expression of Ros1	75.55	0.32	141	27.45
28	INT5206	Gene_expression of AR	113.83	0.78	316	27.29
29	INT145426	Positive_regulation of Ros1	106.76	0.56	185	27.21
30	INT17739	Gene_expression of S100B	132.7	0.78	226	26.4
31	INT11159	Gene_expression of EGFR	548.93	0.78	698	25.69
32	INT28336	Positive_regulation of Pax3	20.94	0.33	37	25.66
33	INT68758	Positive_regulation of Ros1	82.72	0.46	125	25.27
34	INT77793	Positive_regulation of Gdnf	23.76	0.70	54	25.08
35	INT17625	Localization of GCG	55.69	0.80	210	24.97
36	INT23937	Gene_expression of EDNRA	55.63	0.65	103	24.67
37	INT100423	Gene_expression of Bax	98.43	0.75	141	24.48
38	INT47459	Gene_expression of Rac1	45.27	0.68	101	24.33
39	INT9155	Gene_expression of Glul	17.97	0.77	60	23.95
40	INT15458	Gene_expression of NPY	22.67	0.76	50	23.03
41	INT956	Negative_regulation of PRL	42.72	0.59	94	23.01
42	INT72060	Positive_regulation of Gene_expression of Ros1	76.76	0.41	127	20.91
43	INT3593	Gene_expression of ADRA1D	29.48	0.75	70	20.87
44	INT85952	Positive_regulation of AR	64.36	0.67	168	20.66
45	INT53575	Regulation of Gene_expression of Tnf	34.35	0.62	46	20.63
46	INT6699	Positive_regulation of ADRA1D	22.72	0.70	65	20.31
47	INT40750	Gene_expression of Mif	34.59	0.78	61	20.28
48	INT104523	Positive_regulation of FSCN1	10.09	0.12	14	20.08
49	INT53574	Regulation of Tnf	40.68	0.62	45	19.71
50	INT89396	Phosphorylation of AKT1	111.66	0.82	225	19.61
51	INT104527	Binding of FSCN1	14.75	0.23	18	19.6
52	INT7994	Gene_expression of Lta	69.81	0.67	113	19.59
53	INT86187	Positive_regulation of AKT1	122.13	0.69	199	19.44
54	INT11243	Localization of NPY	11.18	0.78	33	19.24
55	INT16445	Gene_expression of IL1A	44.46	0.78	60	19.19
56	INT93734	Positive_regulation of Gene_expression of Bcl2	61.95	0.70	76	18.46
57	INT56749	Gene_expression of PCNA	111.25	0.77	219	18.42
58	INT1060	Negative_regulation of Pla2g1b	22.91	0.57	50	18.12
59	INT107454	Positive_regulation of Stat3	19.63	0.68	43	17.69
60	INT61513	Positive_regulation of Gpx1	37.91	0.64	71	17.07
61	INT65659	Positive_regulation of STAT3	69.56	0.70	132	15.95
62	INT13400	Negative_regulation of Enpep	4.23	0.50	30	15.86
63	INT11508	Positive_regulation of TGFBI	19.81	0.70	24	15.78
64	INT97245	Gene_expression of AKT1	119.63	0.77	217	15.59
65	INT124371	Negative_regulation of Gsk3b	87.92	0.55	170	15.51
66	INT116736	Positive_regulation of Mif	31.93	0.70	40	15.37
67	INT24798	Negative_regulation of Glul	27.25	0.55	52	15.17
68	INT129584	Positive_regulation of Stat3	87.07	0.68	97	14.86
69	INT109511	Gene_expression of Bax	113.22	0.78	133	14.36
70	INT86383	Negative_regulation of EGFR	173.94	0.59	258	13.32
71	INT80222	Negative_regulation of Bcl2	69.16	0.58	82	13.18
72	INT12464	Binding of MET	10.3	0.47	38	13.15
73	INT91817	Positive_regulation of RETNLB	21.4	0.34	22	13.12
74	INT89842	Phosphorylation of Src	9.57	0.69	34	13.08
75	INT46619	Gene_expression of CSF1	36.63	0.73	80	12.94
76	INT2385	Gene_expression of MIF	40.74	0.68	57	12.78
77	INT107875	Phosphorylation of Stat3	13.18	0.80	49	12.66
78	INT89395	Negative_regulation of AKT1	70.27	0.58	127	12.54
79	INT222660	Phosphorylation of Tyr	5.31	0.06	2	12.33
80	INT69436	Negative_regulation of Gene_expression of ROS1	46.58	0.38	81	12.22
81	INT70556	Positive_regulation of Localization of Pax3	3.13	0.34	9	12.11
82	INT121223	Positive_regulation of Gene_expression of Pax3	4.52	0.16	17	12.06
83	INT70555	Regulation of Pax3	3.62	0.35	13	12.05
84	INT100821	Localization of Ros1	45.26	0.60	59	11.92
85	INT70905	Positive_regulation of EDNRA	24.33	0.67	49	11.79
86	INT41313	Gene_expression of Gpx1	34.24	0.78	68	11.77
87	INT81640	Positive_regulation of Gene_expression of Bcl2	84.58	0.69	106	11.63
88	INT19795	Positive_regulation of EGFR	103.69	0.70	161	11.55
89	INT148639	Gene_expression of Uchl1	16.76	0.59	30	11.54
90	INT3597	Positive_regulation of Pla2g1b	17.94	0.63	37	11.41
91	INT2260	Gene_expression of Tyr	7.05	0.49	30	11.31
92	INT15238	Positive_regulation of NPY	11.86	0.67	24	11.26
93	INT48203	Positive_regulation of Tgfb1	41.31	0.70	67	11.07
94	INT221448	Gene_expression of CREG1	27.44	0.05	8	10.87
95	INT79981	Positive_regulation of Gene_expression of Gdnf	12.49	0.70	27	10.77
96	INT60434	Negative_regulation of Positive_regulation of Tnf	10.01	0.46	20	10.64
97	INT15804	Gene_expression of ISG20	44.33	0.75	83	10.58
98	INT82950	Positive_regulation of Gdnf	11.72	0.51	36	10.5
99	INT85844	Regulation of Gdnf	11.08	0.50	18	10.43
100	INT94784	Binding of ROS1	71.57	0.40	113	10.26
101	INT99505	Gene_expression of Bcl2l1	33.12	0.77	42	10.15
102	INT158863	Negative_regulation of Ros1	40.3	0.35	84	10.14
103	INT35612	Gene_expression of REG3A	33.33	0.78	37	10.13
104	INT5788	Gene_expression of IL2RA	40.67	0.75	60	9.98
105	INT44602	Gene_expression of TNFSF13B	30.98	0.75	37	9.96
106	INT7995	Positive_regulation of Lta	14.98	0.66	28	9.8
107	INT203020	Positive_regulation of PYY	18.81	0.68	37	9.63
108	INT102110	Positive_regulation of Gene_expression of Bax	35.77	0.67	42	9.51
109	INT26492	Negative_regulation of Localization of GCG	22.2	0.58	73	9.48
110	INT98111	Negative_regulation of Gdnf	10.85	0.59	12	9.29
111	INT135372	Positive_regulation of Gsk3b	50.03	0.70	72	9.28
112	INT102106	Positive_regulation of Bax	30.62	0.67	48	9.28
113	INT87193	Gene_expression of Tnfrsf1b	29.4	0.58	30	9.22
114	INT64346	Positive_regulation of S100B	63.11	0.70	95	9.17
115	INT89845	Positive_regulation of Src	7.5	0.44	19	9.01
116	INT35366	Binding of AR	30.52	0.47	87	8.9
117	INT141185	Regulation of Ros1	20.73	0.24	30	8.88
118	INT43811	Positive_regulation of Tyr	2.52	0.45	14	8.86
119	INT13010	Gene_expression of TYR	14.81	0.65	38	8.84
120	INT55597	Negative_regulation of Gpx1	28.3	0.55	59	8.83
121	INT109724	Phosphorylation of FSCN1	3.15	0.07	5	8.82
122	INT121599	Negative_regulation of Gene_expression of RETNLB	9.28	0.21	7	8.8
123	INT117553	Regulation of MIF	12.76	0.56	10	8.67
124	INT50767	Positive_regulation of Nanog	3.63	0.67	14	8.56
125	INT77795	Localization of Gdnf	6.29	0.81	26	8.55
126	INT91370	Phosphorylation of STAT3	49.25	0.82	123	8.42
127	INT86672	Negative_regulation of Bcl2	34.16	0.53	50	8.37
128	INT15529	Gene_expression of GCG	18.55	0.75	51	8.35
129	INT114873	Phosphorylation of Stat3	30.19	0.82	63	8.23
130	INT77794	Binding of Gdnf	8.38	0.48	15	8.22
131	INT18185	Gene_expression of Tyr	12.52	0.76	32	8.17
132	INT39170	Gene_expression of TSPO	24.11	0.78	76	8.05
133	INT135443	Phosphorylation of Map2k1	2.44	0.80	11	8.01
134	INT171367	Phosphorylation of Map2k1	32.87	0.58	31	8
135	INT7588	Regulation of NPY	6.97	0.44	13	7.97
136	INT135441	Positive_regulation of Map2k1	6.6	0.67	15	7.87
137	INT80220	Positive_regulation of Bcl2	57.73	0.58	71	7.86
138	INT54978	Binding of EDNRA	14.97	0.41	36	7.86
139	INT28358	Gene_expression of Nanog	3.52	0.70	25	7.85
140	INT92003	Positive_regulation of Transcription of Gdnf	5.54	0.66	10	7.84
141	INT86639	Gene_expression of KRT16	12.44	0.68	19	7.79
142	INT32210	Gene_expression of Mif	28.48	0.75	13	7.79
143	INT87546	Transcription of Gdnf	7.49	0.71	15	7.76
144	INT77306	Negative_regulation of Gene_expression of Bcl2	38.05	0.58	46	7.71
145	INT9398	Localization of MET	2.34	0.78	15	7.69
146	INT113705	Gene_expression of Egfr	149.05	0.78	228	7.59
147	INT19475	Positive_regulation of IL1A	17.99	0.67	20	7.57
148	INT57748	Positive_regulation of Gene_expression of TP53	79.55	0.69	85	7.49
149	INT68299	Binding of Tnf	12.55	0.39	17	7.49
150	INT91445	Regulation of Bcl2	38.8	0.56	50	7.41
151	INT224864	Positive_regulation of KLF10	2.48	0.67	1	7.37
152	INT96994	Phosphorylation of EGFR	52.75	0.82	99	7.33
153	INT9491	Positive_regulation of Ptpn6	2.33	0.51	11	7.32
154	INT151823	Binding of Tnfrsf1b	17.92	0.42	19	7.31
155	INT185905	Gene_expression of CDC25A	4.63	0.41	2	7.29
156	INT72166	Positive_regulation of Gene_expression of RETNLB	10.23	0.24	14	7.27
157	INT29210	Negative_regulation of Terc	1.6	0.37	7	7.21
158	INT83531	Gene_expression of KITLG	26	0.65	54	7.07
159	INT128369	Localization of PYY	10.39	0.79	27	7.06
160	INT127691	Gene_expression of CXCL1	18.11	0.66	23	7.04
161	INT11747	Positive_regulation of IL2RA	16.55	0.67	22	6.95
162	INT118782	Protein_catabolism of Pax3	0.46	0.94	7	6.95
163	INT256	Localization of ADRA1D	2.91	0.78	11	6.85
164	INT69441	Regulation of Gene_expression of ROS1	26.78	0.50	38	6.78
165	INT93101	Regulation of Gene_expression of Bcl2	18.45	0.62	26	6.71
166	INT43721	Gene_expression of Vegfa	36.18	0.77	49	6.63
167	INT61114	Gene_expression of Ppard	14.98	0.75	23	6.62
168	INT50387	Negative_regulation of AR	26.31	0.45	67	6.61
169	INT13385	Gene_expression of Bad	41.86	0.76	60	6.52
170	INT93137	Negative_regulation of Map2k1	4.51	0.42	17	6.49
171	INT98837	Positive_regulation of Bax	63.14	0.61	72	6.41
172	INT21613	Gene_expression of Pla2g1b	9.05	0.68	25	6.39
173	INT11154	Binding of EGFR	96.23	0.48	149	6.29
174	INT129918	Positive_regulation of Phosphorylation of Stat3	5.42	0.63	17	6.28
175	INT38595	Localization of BCAR1	2.9	0.73	8	6.25
176	INT14258	Regulation of TSPO	10.16	0.60	32	6.24
177	INT4911	Negative_regulation of Binding of Pax3	1.89	0.22	7	6.17
178	INT15528	Positive_regulation of GCG	20.47	0.63	38	6.14
179	INT189177	Positive_regulation of Gene_expression of FSCN1	3.77	0.11	12	6.12
180	INT99506	Negative_regulation of Bcl2l1	15.7	0.58	25	6.09
181	INT121370	Positive_regulation of MIF	17.79	0.70	22	6.08
182	INT516	Negative_regulation of Mif	6.69	0.59	13	6.08
183	INT144086	Positive_regulation of Prok2	9.54	0.69	12	6.06
184	INT178604	Gene_expression of TPX2	20.29	0.37	13	6.04
185	INT143357	Binding of Ros1	27.76	0.36	48	6
186	INT91159	Negative_regulation of Ros1	26.12	0.44	35	5.97
187	INT103918	Phosphorylation of Tyr	10.12	0.47	12	5.96
188	INT6913	Negative_regulation of Amelx	2.32	0.32	6	5.95
189	INT93684	Gene_expression of STAT3	34.42	0.78	66	5.94
190	INT87548	Negative_regulation of Gene_expression of Gdnf	5.67	0.54	9	5.94
191	INT8157	Binding of Tyr	0.64	0.09	14	5.89
192	INT95616	Gene_expression of Thpo	21.51	0.78	48	5.88
193	INT115087	Negative_regulation of Gdnf	5.78	0.51	10	5.73
194	INT31227	Regulation of Localization of GCG	4.86	0.48	28	5.72
195	INT50975	Localization of Ptpn6	2.64	0.65	8	5.7
196	INT6487	Positive_regulation of Positive_regulation of Tnf	16.06	0.56	21	5.64
197	INT131944	Gene_expression of Mki67	6.58	0.53	30	5.63
198	INT112124	Positive_regulation of Egfr	47.82	0.70	71	5.61
199	INT102836	Binding of LRP2	11.27	0.38	12	5.58
200	INT58468	Negative_regulation of Gene_expression of IL1A	9.39	0.58	10	5.57