GOS:cytoskeleton

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoskeleton. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cytoskeleton. They are ordered first by their pain relevance and then by number of times they were reported for cytoskeleton. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Genes linked to cytoskeleton	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT317511	Ppp1r9b Regulation of Oprm1	1	3	0.27	0.33	3.85
2	INT317517	Binding of Nos1 and Oprm1	1	1	0.17	0.22	3.85
3	INT143946	Binding of Pebp1 and Mastl	1	1	0.00	2.04	3.82
4	INT180813	Ngf Positive_regulation of Sorbs1	1	1	0.04	2.09	3.79
5	INT302118	Binding of Oprm1 and Ppp1r9b	1	2	0.24	0.26	3.45
6	INT108472	Binding of NOS1 and PNOC	1	1	0.32	0.64	3.27
7	INT317522	Akt1 Positive_regulation of Phosphorylation of Nos1	1	1	0.43	0.4	3.13
8	INT100835	Binding of Calca and Akap12	1	1	0.07	0.41	2.92
9	INT229497	Binding of Vim and Ndel1	2	1	0.33	3.5	2.81
10	INT87267	Binding of BMP8B and KRIT1	1	1	0.06	0.16	2.69
11	INT259231	Binding of Oprm1 and Ppp1r9b	1	1	0.01	0	2.67
12	INT251150	Binding of Nos1 and Dlg2	1	1	0.30	1.98	2.62
13	INT223866	Ltp Positive_regulation of Positive_regulation of Mapk1	1	2	0.46	0.75	2.61
14	INT317528	Ppp1r9b Regulation of Grin1	1	1	0.18	0.2	2.48
15	INT107578	Kitl Negative_regulation of Grin2b	1	1	0.12	2.05	2.36
16	INT238914	Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1	1	1	0.19	3.22	2.35
17	INT284860	Binding of Pdzd2 and Nav1	1	9	0.29	2.33	2.34
18	INT128778	Binding of Mcam and Nav1	1	1	0.03	0.51	2.28
19	INT128777	Binding of Cntn1 and Nav1	1	1	0.48	0.51	2.28
20	INT140019	Avp Positive_regulation of Localization of Kitl	1	1	0.00	1	2.13
21	INT351380	Ngf Regulation of TPM1	1	1	0.44	2.17	2.11
22	INT133946	Binding of DNM2 and OPRK1	1	1	0.11	0	2.1
23	INT122660	Binding of CACNA1A and DNAH8	1	2	0.28	2.68	2.08
24	INT281084	Prkaca Positive_regulation of Mapk1	1	2	0.25	0	2.06
25	INT349608	Binding of DIO2 and LMOD1	1	1	0.23	0.41	2.01
26	INT69556	Slc7a11 Regulation of Cpe	1	2	0.06	0.46	1.95
27	INT227493	Binding of TCEA1 and SIRT2	1	1	0.01	1.55	1.93
28	INT151965	SORBS1 Positive_regulation of TRPV1	1	1	0.18	0	1.89
29	INT169346	Nxn Negative_regulation of Dynll1	2	1	0.06	1.22	1.87
30	INT13940	DNM2 Regulation of Localization of CGA	1	1	0.11	0	1.86
31	INT349658	Nos2 Regulation of Gene_expression of Nos1	1	1	0.63	2.86	1.84
32	INT142899	Chn1 Negative_regulation of Positive_regulation of NOS1	1	1	0.01	1.07	1.75
33	INT346217	Braf Positive_regulation of Phosphorylation of Map2k1	1	1	0.22	3.23	1.72
34	INT282398	Binding of Mefv and Nlrp3	1	1	0.40	6.8	1.72
35	INT30134	Binding of TPP1 and S100A9	1	1	0.13	0.74	1.69
36	INT278223	Binding of NOS3 and ACSM3	1	1	0.41	6.32	1.65
37	INT168612	Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9	1	1	0.23	0.45	1.62
38	INT140023	Avp Positive_regulation of Gene_expression of Kitl	1	1	0.00	0.76	1.62
39	INT107965	Binding of HLA-B and Mefv	1	2	0.34	3.91	1.61
40	INT168607	Negative_regulation of Nos1 Negative_regulation of Mmp9	1	1	0.23	0.45	1.61
41	INT180812	Gdnf Positive_regulation of Gene_expression of Sorbs1	1	1	0.02	0.83	1.61
42	INT180811	Gdnf Positive_regulation of Regulation of Sorbs1	1	1	0.01	0.83	1.61
43	INT12327	Igh-Dex Positive_regulation of Plec	1	1	0.03	0.73	1.57
44	INT144280	ACP1 Negative_regulation of Phosphorylation of MAPK1	1	1	0.37	0.78	1.56
45	INT315284	PRKG1 Positive_regulation of Nos1	1	1	0.33	0.85	1.56
46	INT113337	EPO Positive_regulation of JAK2	1	1	0.76	2.8	1.55
47	INT249498	Src Positive_regulation of Phosphorylation of Grin2b	1	1	0.22	1.11	1.54
48	INT253863	Binding of LBP and PNP	1	1	0.13	1.5	1.5
49	INT45502	TNS1 Positive_regulation of VIP	1	1	0.47	0.52	1.5
50	INT93781	Racgap1 Positive_regulation of Positive_regulation of Gnptab	1	1	0.02	0.07	1.49
51	INT93782	Racgap1 Positive_regulation of Rgs9	1	1	0.55	0.07	1.49
52	INT93783	Racgap1 Positive_regulation of Gnptab	1	1	0.02	0.07	1.49
53	INT334633	Binding of Cntnap1 and Nav1	1	1	0.10	1.36	1.48
54	INT158711	Cdk5 Positive_regulation of Phosphorylation of Trh	1	1	0.02	0	1.46
55	INT131040	Binding of Oprm1 and S100a9	1	1	0.24	0	1.45
56	INT169800	Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1	1	1	0.39	1.04	1.45
57	INT150392	Binding of MEFV and PSTPIP1	2	2	0.51	10.49	1.44
58	INT180804	Bdnf Positive_regulation of Gene_expression of Sorbs1	1	1	0.01	0	1.44
59	INT261831	Mapk1 Negative_regulation of Hspg2	1	1	0.00	1.26	1.42
60	INT148450	Gene_expression of Inhbe Positive_regulation of Mapk1	1	1	0.07	1.35	1.41
61	INT161670	H2-M3 Positive_regulation of Positive_regulation of Mapk1	1	1	0.14	0.73	1.41
62	INT180809	Ngf Positive_regulation of Positive_regulation of Sorbs1	1	1	0.03	0.84	1.4
63	INT134764	Ghrl Regulation of Gene_expression of NOS3	1	1	0.02	2.66	1.4
64	INT180808	Ngf Positive_regulation of Gene_expression of Sorbs1	1	1	0.03	0.84	1.4
65	INT197111	Binding of IL1B and MCF2	1	1	0.02	2.12	1.4
66	INT133933	Binding of DNM2 and TP53INP2	1	1	0.00	0	1.38
67	INT87266	Negative_regulation of Binding of BMP8B and KRIT1	1	1	0.05	0.07	1.37
68	INT229496	Binding of Ndel1 and Gopc	1	1	0.08	2.05	1.36
69	INT106062	Positive_regulation of Oprl1 Positive_regulation of Mapk1	1	1	0.13	0.16	1.35
70	INT106071	Positive_regulation of Oprl1 Positive_regulation of MAPK3	1	1	0.12	0.16	1.34
71	INT180802	Gdnf Positive_regulation of Sorbs1	1	1	0.02	0.98	1.34
72	INT259211	Binding of Ppp1r9b and Flna	1	1	0.06	0	1.33
73	INT145473	Mastl Positive_regulation of Dnahc8	2	1	0.07	0.06	1.33
74	INT180807	Calca Regulation of Sorbs1	1	1	0.02	0	1.32
75	INT130786	Positive_regulation of Oprm1 Positive_regulation of Arc	1	1	0.27	0.9	1.31
76	INT198957	Binding of Cnr1 and Mastl	1	1	0.00	0	1.31
77	INT341336	Binding of Pepd and Nav1	1	1	0.07	0.92	1.3
78	INT261841	Mastl Positive_regulation of Trpa1	1	1	0.00	0.82	1.3
79	INT113844	CDKN1A Negative_regulation of CDK2	1	4	0.49	1.18	1.27
80	INT84886	APC Regulation of PPARD	1	1	0.51	1.57	1.26
81	INT121464	Negative_regulation of Oprm1 Positive_regulation of Dnm2	1	1	0.34	0	1.26
82	INT73710	Mastl Positive_regulation of Localization of Oprl1	1	1	0.02	0	1.26
83	INT342165	Binding of Aqp1 and Nav1	1	1	0.25	0.57	1.25
84	INT317569	Prkca Positive_regulation of Phosphorylation of Src	1	1	0.11	0	1.25
85	INT132465	Ltf Positive_regulation of Nos1	1	1	0.35	0.05	1.24
86	INT121465	Binding of Dnm2 and Oprm1	1	1	0.23	0	1.24
87	INT136257	Tff3 Regulation of SGCG	1	1	0.00	0.18	1.24
88	INT21858	Maoa Regulation of Gene_expression of Spna1	1	1	0.12	0.18	1.24
89	INT136256	Creb1 Regulation of SGCG	1	1	0.26	0.18	1.23
90	INT249487	Binding of Ephb1 and Src	1	1	0.17	0.74	1.23
91	INT21859	Maoa Regulation of Spna1	1	1	0.12	0.18	1.23
92	INT166388	Binding of Gnb2l1 and Mapk1	2	1	0.49	0.49	1.21
93	INT299299	VEGFA Positive_regulation of SRC	1	1	0.20	0.91	1.2
94	INT228681	Fkbp4 Negative_regulation of Trib3	1	1	0.00	0.57	1.2
95	INT70288	Negative_regulation of Atxn2l Positive_regulation of Racgap1	1	1	0.02	0.3	1.19
96	INT75483	Binding of SGCG and TGFB1	1	1	0.52	2.27	1.19
97	INT139736	Htr1a Positive_regulation of Mapk3	1	1	0.54	0.13	1.19
98	INT94091	Binding of Pnoc and Tbce	1	1	0.03	0.19	1.19
99	INT121191	KCNMA1 Positive_regulation of Phosphorylation of MAPK1	1	1	0.06	0.61	1.18
100	INT107579	Kitl Negative_regulation of Grin2a	1	1	0.10	1.02	1.18
101	INT150835	Gper Positive_regulation of Localization of Prkce	1	1	0.15	0.62	1.18
102	INT49956	OPRM1 Positive_regulation of SGCG	1	1	0.53	0.3	1.18
103	INT146352	Binding of Rgs14 and Mors1	1	1	0.23	0.27	1.17
104	INT153588	Binding of HINT1 and Oprm1	1	1	0.06	0	1.17
105	INT169557	Cacna1h Positive_regulation of Mapk1	1	1	0.07	0.91	1.17
106	INT238916	CNR1 Positive_regulation of Phosphorylation of MAPK1	1	1	0.19	1.61	1.17
107	INT161510	Tlr4 Positive_regulation of Mapk1	1	1	0.14	0.3	1.16
108	INT70289	Atxn2l Positive_regulation of Racgap1	1	1	0.04	0.29	1.15
109	INT69504	Binding of Nos1 and Gatm	1	1	0.05	0	1.13
110	INT249488	Positive_regulation of Binding of Ephb1 and Src	1	1	0.23	0.68	1.12
111	INT161512	Ppig Negative_regulation of Positive_regulation of S100a8	1	1	0.02	0.23	1.12
112	INT99577	Binding of KITLG and Kit	1	3	0.34	2.33	1.11
113	INT142572	D5Pas1 Negative_regulation of Nos1	1	2	0.02	0.14	1.11
114	INT62381	ADCY10 Positive_regulation of Localization of IGHG3	1	1	0.04	0.36	1.11
115	INT62380	ADCY10 Positive_regulation of IGHG3	1	1	0.03	0.36	1.11
116	INT317527	Binding of Hint1 and Nos1	1	1	0.27	0.1	1.11
117	INT134870	Regulation of Binding of Calm3 and Nav1	1	1	0.17	0.42	1.1
118	INT134869	Binding of Calm3 and Nav1	1	1	0.31	0.42	1.1
119	INT164378	MAPK3 Positive_regulation of Transcription of PDYN	1	1	0.50	0.2	1.09
120	INT164382	MAPK3 Positive_regulation of Gene_expression of Fos	1	1	0.75	0.2	1.08
121	INT164383	Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos	1	1	0.54	0.2	1.08
122	INT96905	Plxna3 Regulation of Regulation of Prkce	1	1	0.18	0.71	1.07
123	INT81582	Plec Positive_regulation of st	1	1	0.02	0	1.07
124	INT81581	Plec Positive_regulation of Nudt14	1	1	0.01	0	1.07
125	INT83936	Binding of Mtap2 and Penk	1	1	0.22	0.19	1.07
126	INT218846	Ppp1r9a Regulation of Ltp	1	1	0.15	2.24	1.07
127	INT296460	Binding of Gria2 and Myo18a	1	1	0.01	1.49	1.06
128	INT18828	DNM2 Positive_regulation of Localization of LTB4R	1	1	0.01	0.07	1.06
129	INT146496	Snta1 Positive_regulation of Gene_expression of Adrbk1	1	1	0.13	0.73	1.05
130	INT119887	Binding of Atf4 and Usf1	1	1	0.21	0.15	1.05
131	INT97013	Negative_regulation of Binding of CALM3 and OPRM1	1	1	0.40	0	1.05
132	INT97011	Binding of CALM3 and OPRM1	1	1	0.35	0	1.05
133	INT180806	Ngf Positive_regulation of Regulation of Sorbs1	1	1	0.03	0.28	1.04
134	INT128700	BBS9 Negative_regulation of Il12a	1	1	0.47	0.76	1.03
135	INT132464	Ltf Negative_regulation of Positive_regulation of Nos1	1	1	0.33	0	1.03
136	INT101067	MAP3K15 Positive_regulation of MAPK1	1	1	0.21	0.47	1.03
137	INT225158	Binding of CDK2 and CDKN1A	1	7	0.30	3.26	1.02
138	INT229914	Egr1 Positive_regulation of Phosphorylation of Mapk3	1	1	0.46	1.03	1.02
139	INT121743	Negative_regulation of Src Negative_regulation of Ephb1	1	1	0.27	0	1.02
140	INT144661	Dnm1 Negative_regulation of Binding of Hbegf and	1	1	0.24	0	1.01
141	INT119914	Olr1714 Negative_regulation of Nos1	1	1	0.02	0.47	1.01
142	INT30135	S100A9 Positive_regulation of REN	1	1	0.32	0.32	1
143	INT53844	Penk Regulation of Kitl	1	1	0.00	0.9	1
144	INT317518	Src Regulation of Negative_regulation of Oprm1	1	1	0.16	0.07	1
145	INT317555	Nos1 Regulation of Negative_regulation of Oprm1	1	1	0.21	0.07	1
146	INT221747	Gtf3a Positive_regulation of Positive_regulation of Racgap1	1	1	0.00	0.33	1
147	INT53845	Positive_regulation of Penk Regulation of Kitl	1	1	0.00	0.9	1
148	INT18139	Binding of Penk and Stmn1	1	1	0.08	0	0.99
149	INT143915	Src Regulation of Rbm39	1	1	0.03	0.18	0.99
150	INT59518	YY1 Positive_regulation of SGCG	1	1	0.50	0.32	0.99
151	INT140652	IGF1 Positive_regulation of Phosphorylation of MAPK1	1	1	0.26	0.63	0.98
152	INT133616	Map2k1 Regulation of Fadd	1	1	0.04	0.29	0.97
153	INT133614	Map2k1 Regulation of Daxx	1	1	0.02	0.29	0.97
154	INT133615	Regulation of Map2k1 Regulation of Fadd	1	1	0.04	0.29	0.97
155	INT346204	Binding of S100A10 and TPPP	1	1	0.02	1.62	0.97
156	INT89828	Atp4b Positive_regulation of Localization of Grip2	1	1	0.10	0.54	0.97
157	INT121744	Src Positive_regulation of Positive_regulation of Ephb1	1	1	0.35	0	0.96
158	INT317567	Binding of Akt1 and Nos1	1	1	0.22	0	0.96
159	INT180803	Sorbs1 Regulation of Gdnf	1	1	0.01	0.28	0.95
160	INT100018	TNF Positive_regulation of MAPK1	1	3	0.24	1.56	0.94
161	INT214411	DNAH8 Regulation of CAPN1	1	1	0.00	1.01	0.94
162	INT214408	ATP1A4 Regulation of DNAH8	1	1	0.04	1.01	0.94
163	INT139330	Binding of SGCG and Stat1	1	1	0.37	0.75	0.94
164	INT252877	Prkaca Positive_regulation of Regulation of Grip2	1	1	0.01	0.22	0.94
165	INT144281	ACP1 Negative_regulation of Positive_regulation of MAPK1	1	1	0.27	0.58	0.94
166	INT252878	Prkaca Regulation of Regulation of Grip2	1	1	0.01	0.22	0.94
167	INT144285	ACP1 Negative_regulation of MAPK1	1	1	0.37	0.58	0.93
168	INT116930	OPRK1 Positive_regulation of Binding of PTK2 and	1	1	0.28	0.35	0.93
169	INT223871	Ltp Positive_regulation of Gene_expression of Mapk1	1	1	0.33	0	0.93
170	INT65462	Bri3 Negative_regulation of Racgap1	1	1	0.02	0.39	0.93
171	INT220031	Casp3 Positive_regulation of Gene_expression of Nos3	1	1	0.04	0	0.92
172	INT122269	Src Negative_regulation of Positive_regulation of Grin2b	1	1	0.27	0.44	0.92
173	INT151263	Jun Positive_regulation of S100a8	1	1	0.00	0.95	0.92
174	INT302828	Mapkapk5 Positive_regulation of Mapk1	1	1	0.07	1.38	0.91
175	INT135446	Map2k1 Positive_regulation of Mapk3	2	1	0.54	0.25	0.91
176	INT343918	IgG Positive_regulation of Phosphorylation of MAPK1	1	1	0.01	3.57	0.91
177	INT63488	Sptan1 Positive_regulation of Rtcd1	1	1	0.03	0.34	0.91
178	INT109842	Prkce Positive_regulation of Localization of Trpv1	1	1	0.13	1.31	0.91
179	INT54202	Gnai1 Negative_regulation of Binding of Pag1 and Agp2	1	1	0.01	0.18	0.91
180	INT122266	Src Negative_regulation of Grin2b	1	1	0.27	0.43	0.91
181	INT54200	Gnai1 Negative_regulation of Pag1	1	1	0.05	0.18	0.9
182	INT54197	Binding of Gnai1 and Pag1	1	1	0.04	0.18	0.9
183	INT317530	Negative_regulation of Binding of Nos1 and Oprm1	1	1	0.21	0.06	0.9
184	INT52759	Oprd1 Regulation of Sptan1	1	1	0.03	0	0.9
185	INT54187	Gnai1 Negative_regulation of Binding of Oprd1 and Pag1	1	1	0.00	0.18	0.9
186	INT54854	Sorbs1 Regulation of Ins1	1	1	0.34	0.23	0.9
187	INT52761	Dll1 Regulation of Sptan1	1	1	0.07	0	0.89
188	INT292988	Negative_regulation of SGCG Positive_regulation of GABRB3	1	1	0.01	0.3	0.89
189	INT301079	Binding of GNAT1 and INPP5E	1	1	0.00	0.59	0.89
190	INT284855	Binding of S100a10 and Nav1	1	4	0.21	0.99	0.88
191	INT159962	Rock2 Regulation of Localization of Il6	1	1	0.09	2.7	0.88
192	INT326663	Bdnf Regulation of Positive_regulation of Arc	1	1	0.16	1.46	0.88
193	INT188196	LIF Regulation of MAPK1	1	1	0.21	2.26	0.87
194	INT97738	Mdk Positive_regulation of Mapk3	1	1	0.08	0.66	0.87
195	INT292990	SGCG Positive_regulation of Gene_expression of GABRB3	1	1	0.01	0.29	0.87
196	INT203148	Mif Positive_regulation of Gene_expression of S100a8	1	1	0.00	1.56	0.87
197	INT292987	SGCG Positive_regulation of NCOR2	1	1	0.00	0.29	0.87
198	INT343847	IRF6 Positive_regulation of TBCE	1	1	0.01	1.11	0.87
199	INT292989	SGCG Positive_regulation of GABRB3	1	1	0.01	0.29	0.87
200	INT188214	OSM Regulation of MAPK1	1	1	0.20	2.27	0.87

Single Events

The table below shows the top 100 pain related interactions that have been reported for cytoskeleton. They are ordered first by their pain relevance and then by number of times they were reported in cytoskeleton. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT94450	Gene_expression of Nav1	359	0.78	131.85	275.46
2	INT95787	Positive_regulation of Mapk1	568	0.70	226.51	220.94
3	INT62124	Gene_expression of NOS1	444	0.78	218.08	114.85
4	INT48593	Positive_regulation of NOS1	420	0.68	226.15	114.71
5	INT49171	Gene_expression of Nos1	241	0.78	140.7	104.76
6	INT74058	Gene_expression of Nos1	260	0.78	80.04	95.71
7	INT48767	Negative_regulation of NOS1	312	0.59	154.25	90.32
8	INT71789	Positive_regulation of MAPK1	396	0.70	234.44	89.27
9	INT82448	Gene_expression of S100a8	246	0.77	236.72	84.02
10	INT92434	Phosphorylation of Mapk1	287	0.82	91.65	83.46
11	INT48934	Positive_regulation of Mapk1	157	0.70	60.61	61.72
12	INT79093	Positive_regulation of Nos1	101	0.70	46.89	59.61
13	INT49170	Negative_regulation of Nos1	116	0.59	60.66	58.87
14	INT647	Gene_expression of SGCG	211	0.75	78.46	55.82
15	INT61873	Gene_expression of Arc	128	0.78	128.25	52.24
16	INT64110	Positive_regulation of Gene_expression of Nos1	68	0.70	58.11	51.64
17	INT83199	Gene_expression of Nos3	193	0.78	100.72	51.57
18	INT49028	Positive_regulation of Nos1	102	0.70	34.73	51.05
19	INT111051	Negative_regulation of Nav1	64	0.59	25.51	47.27
20	INT71786	Phosphorylation of MAPK1	256	0.82	110.09	46.17
21	INT1726	Positive_regulation of Kitl	65	0.70	38.81	44.85
22	INT65245	Gene_expression of Nos3	121	0.78	98.14	41.56
23	INT97596	Localization of S100a8	94	0.78	90.69	40.41
24	INT92437	Positive_regulation of Phosphorylation of Mapk1	113	0.70	32.19	40.29
25	INT114751	Gene_expression of Mapk1	137	0.76	60.14	39.98
26	INT102611	Negative_regulation of Positive_regulation of Mapk1	74	0.58	35.57	39.37
27	INT103261	Positive_regulation of Nav1	68	0.70	24.25	39.27
28	INT116321	Regulation of Nav1	38	0.62	26.62	37.97
29	INT48933	Gene_expression of Mapk3	93	0.75	44.39	37.92
30	INT64558	Negative_regulation of Nos1	88	0.58	26.76	36.78
31	INT111052	Positive_regulation of Gene_expression of Nav1	44	0.70	18.98	35.28
32	INT103262	Localization of Nav1	53	0.81	19.23	34.44
33	INT109434	Phosphorylation of Mapk1	110	0.82	61.64	34.05
34	INT48924	Positive_regulation of Mapk3	107	0.67	50.53	34.05
35	INT48925	Gene_expression of Mapk1	95	0.74	42.21	32.91
36	INT117112	Negative_regulation of Mapk1	87	0.56	40.34	31.18
37	INT49110	Regulation of Grip2	46	0.61	13.57	30.87
38	INT72375	Phosphorylation of Mapk3	87	0.80	43.66	30.27
39	INT719	Negative_regulation of SGCG	96	0.57	47.91	30.22
40	INT7664	Negative_regulation of Grip2	68	0.49	10.11	29.93
41	INT64113	Positive_regulation of Gene_expression of NOS1	110	0.60	71.03	29.72
42	INT83708	Negative_regulation of MAPK1	156	0.57	84.93	27.85
43	INT56524	Gene_expression of Grip2	67	0.74	14.77	26.23
44	INT48832	Positive_regulation of Grip2	48	0.69	12.13	25.99
45	INT95788	Positive_regulation of Positive_regulation of Mapk1	83	0.69	24.75	25.84
46	INT12124	Gene_expression of MAPK1	141	0.75	82.4	25.58
47	INT74688	Regulation of Nos1	55	0.62	22.16	25.3
48	INT10929	Positive_regulation of FLII	46	0.67	13.17	24.63
49	INT48766	Regulation of NOS1	73	0.61	37.01	24.59
50	INT71781	Phosphorylation of MAPK3	62	0.80	27.73	23.73
51	INT49172	Regulation of Nos1	43	0.52	27.53	23.66
52	INT9292	Positive_regulation of SGCG	93	0.67	35.13	23.48
53	INT1221	Regulation of SGCG	65	0.60	24.21	22.94
54	INT83797	Gene_expression of Bcl2l1	124	0.77	94.55	22.39
55	INT1558	Positive_regulation of Dnahc8	30	0.69	5.78	22.19
56	INT70504	Regulation of Gene_expression of NOS1	30	0.51	21.72	21.72
57	INT74059	Positive_regulation of Gene_expression of Nos1	55	0.70	11.5	21.39
58	INT1561	Negative_regulation of Dnahc8	59	0.59	18.12	20.99
59	INT1756	Negative_regulation of DNAH8	105	0.59	42.73	20.24
60	INT292049	Gene_expression of Csnk1a1	1	0.59	28.22	19.53
61	INT12725	Positive_regulation of Racgap1	66	0.68	32.74	19.29
62	INT91462	Positive_regulation of Phosphorylation of MAPK1	99	0.67	40.28	18.99
63	INT71787	Positive_regulation of MAPK3	37	0.67	17.5	17.88
64	INT83198	Positive_regulation of Nos3	78	0.64	35.69	17.71
65	INT10555	Gene_expression of FLII	37	0.75	7.81	17.6
66	INT3364	Binding of SGCG	87	0.47	31.93	17.24
67	INT111050	Negative_regulation of Gene_expression of Nav1	23	0.58	5.97	17.06
68	INT24225	Gene_expression of Alms1	93	0.62	52.75	16.93
69	INT48690	Localization of Grip2	33	0.61	6.13	16.81
70	INT49263	Binding of Grip2	31	0.41	9.86	16.38
71	INT5841	Gene_expression of Vim	181	0.72	138.54	16.33
72	INT95790	Regulation of Mapk1	55	0.61	21.17	16.31
73	INT10214	Gene_expression of VIM	153	0.78	115.88	16.29
74	INT113384	Regulation of Gene_expression of Nav1	20	0.62	8.57	16.15
75	INT114025	Transcription of Nos1	20	0.70	16.48	15.63
76	INT20966	Positive_regulation of Arc	30	0.70	24.38	15.62
77	INT111462	Negative_regulation of Phosphorylation of Mapk1	45	0.57	19.49	15.59
78	INT112207	Binding of Nav1	27	0.47	7.1	15.43
79	INT75531	Regulation of MAPK1	70	0.61	34.39	15.42
80	INT152730	Positive_regulation of S100a8	48	0.68	47.67	15.4
81	INT128401	Positive_regulation of Positive_regulation of Mapk1	39	0.70	10.88	15.38
82	INT116465	Gene_expression of Birc5	241	0.78	192.31	15.32
83	INT170335	Gene_expression of INCENP	176	0.54	91.62	15.31
84	INT16167	Negative_regulation of DMD	186	0.57	108.71	15.25
85	INT16166	Positive_regulation of DMD	348	0.67	133.22	15.06
86	INT74098	Negative_regulation of Gene_expression of Nos1	36	0.59	16.25	14.82
87	INT64112	Regulation of Gene_expression of Nos1	22	0.62	21.45	14.76
88	INT1556	Regulation of Dnahc8	20	0.61	3.23	14.44
89	INT36262	Positive_regulation of Tbce	35	0.49	28.79	14.33
90	INT80688	Positive_regulation of Positive_regulation of MAPK1	72	0.69	39.35	14.11
91	INT36177	Binding of Alms1	70	0.31	35.47	13.81
92	INT5207	Negative_regulation of Alms1	70	0.41	41.56	13.68
93	INT152729	Negative_regulation of Gene_expression of S100a8	33	0.42	32.25	13.64
94	INT12325	Gene_expression of Plec	47	0.72	11.92	13.35
95	INT30117	Gene_expression of Calm1	18	0.71	17.45	13.18
96	INT89842	Phosphorylation of Src	34	0.69	9.57	13.08
97	INT121783	Positive_regulation of Gene_expression of Arc	30	0.70	29.22	13.02
98	INT83200	Positive_regulation of Gene_expression of Nos3	48	0.70	24.75	12.99
99	INT174838	Localization of INCENP	80	0.64	19.05	12.89
100	INT123593	Gene_expression of Snca	58	0.78	35.76	12.87
101	INT48927	Regulation of Mapk3	25	0.60	14.06	12.82
102	INT109223	Negative_regulation of Cdk5	14	0.59	3.27	12.73
103	INT121242	Positive_regulation of Gene_expression of Nos3	37	0.69	31.96	12.71
104	INT74838	Positive_regulation of Sorbs1	18	0.34	6.93	12.63
105	INT83201	Gene_expression of NOS3	93	0.78	47.16	12.48
106	INT90909	Negative_regulation of Gene_expression of NOS1	44	0.55	23.83	12.47
107	INT35801	Regulation of Alms1	34	0.38	20.88	12.38
108	INT150676	Positive_regulation of Gene_expression of Mapk1	30	0.45	10.06	12.37
109	INT119396	Regulation of Positive_regulation of Mapk1	22	0.61	7.88	12.25
110	INT48335	Negative_regulation of NOSTRIN	38	0.56	16.22	12.05
111	INT146197	Positive_regulation of Rhoa	60	0.68	34.12	12.02
112	INT8533	Regulation of Sorbs1	9	0.27	3.01	11.98
113	INT127565	Positive_regulation of ENC1	2	0.39	11.67	11.82
114	INT21850	Gene_expression of Spna1	107	0.50	51.4	11.81
115	INT73431	Positive_regulation of Nos3	82	0.65	53.22	11.61
116	INT47702	Gene_expression of Sptan1	24	0.76	7.6	11.36
117	INT80251	Binding of Nos1	21	0.30	8.24	11.31
118	INT73959	Positive_regulation of NOSTRIN	49	0.61	31.1	11.27
119	INT25963	Gene_expression of DES	122	0.75	98.81	11.25
120	INT88650	Negative_regulation of Prkce	13	0.57	11.93	11.16
121	INT75525	Negative_regulation of Positive_regulation of MAPK1	40	0.59	25.15	11.15
122	INT60500	Negative_regulation of Tbce	21	0.41	13.3	11.1
123	INT91357	Regulation of Dnm2	5	0.61	0	11.06
124	INT48912	Localization of NOS1	52	0.77	24.14	10.92
125	INT62895	Gene_expression of NOSTRIN	51	0.75	28.8	10.68
126	INT90114	Regulation of Gene_expression of Nos1	18	0.62	6.38	10.52
127	INT228884	Localization of Akap12	1	0.52	1.72	10.52
128	INT1934	Positive_regulation of Cys1	68	0.68	60.56	10.47
129	INT86464	Binding of LMOD1	31	0.44	10.23	10.46
130	INT86361	Positive_regulation of Positive_regulation of NOS1	39	0.53	18.93	10.42
131	INT48921	Regulation of Mapk1	25	0.49	19.51	10.41
132	INT91948	Positive_regulation of Prkce	16	0.64	11.36	10.32
133	INT110017	Phosphorylation of Nos1	12	0.60	1.64	10.3
134	INT790	Gene_expression of Mastl	22	0.68	4.56	10.23
135	INT99505	Gene_expression of Bcl2l1	42	0.77	33.12	10.15
136	INT127123	Positive_regulation of Snca	35	0.70	14.76	10.1
137	INT98130	Positive_regulation of CASP8	79	0.67	65.29	10.08
138	INT61171	Gene_expression of S100A8	92	0.76	57.74	9.98
139	INT108405	Gene_expression of FAAH	48	0.78	28.22	9.97
140	INT95271	Negative_regulation of Nos3	46	0.53	24.1	9.71
141	INT159116	Gene_expression of Gnb2l1	12	0.77	2.79	9.49
142	INT56985	Gene_expression of MEFV	56	0.71	46.71	9.47
143	INT62254	Negative_regulation of FLII	20	0.48	4.11	9.44
144	INT133118	Negative_regulation of FAAH	25	0.59	13.05	9.37
145	INT106595	Negative_regulation of Dnm2	10	0.58	0.15	9.29
146	INT21846	Localization of Spna1	27	0.78	5.14	9.22
147	INT63701	Localization of KRIT1	11	0.78	2.02	9.17
148	INT94196	Negative_regulation of Phosphorylation of MAPK1	60	0.59	31.64	9.16
149	INT8535	Localization of Sorbs1	9	0.80	2.71	9.07
150	INT163054	Gene_expression of Msn	20	0.66	0.6	9.06
151	INT35269	Localization of SGCG	38	0.78	14.68	9.01
152	INT89845	Positive_regulation of Src	19	0.44	7.5	9.01
153	INT156874	Positive_regulation of Gene_expression of S100a8	26	0.49	32.8	8.99
154	INT109432	Negative_regulation of Phosphorylation of Mapk1	19	0.54	7.01	8.98
155	INT101602	Positive_regulation of Cdk5	15	0.70	4.1	8.96
156	INT111133	Negative_regulation of Mapk3	31	0.57	10.89	8.9
157	INT97312	Gene_expression of S100a8	19	0.78	16.26	8.88
158	INT232307	Localization of Calm1	5	0.74	9.99	8.71
159	INT57057	Gene_expression of APC	131	0.78	122.24	8.7
160	INT127555	Negative_regulation of Cdk5	59	0.59	50.2	8.45
161	INT48908	Transcription of NOS1	27	0.55	13.46	8.39
162	INT126848	Positive_regulation of Phosphorylation of Mapk1	30	0.50	15.94	8.34
163	INT4991	Positive_regulation of Vim	74	0.69	69.84	8.33
164	INT157580	Phosphorylation of Cdk5	4	0.77	0.73	8.33
165	INT114171	Phosphorylation of Grip2	11	0.49	5.75	8.31
166	INT84672	Negative_regulation of Positive_regulation of Nos1	12	0.48	3.76	8.27
167	INT71785	Gene_expression of MAPK3	22	0.75	11.35	8.21
168	INT63852	Gene_expression of Gphn	21	0.63	5.64	8.2
169	INT60285	Negative_regulation of Racgap1	27	0.56	21.71	8.14
170	INT72539	Gene_expression of Sorbs1	10	0.78	4.98	8.14
171	INT95414	Positive_regulation of Alms1	40	0.41	20.3	8.1
172	INT67374	Gene_expression of Mefv	15	0.74	49.1	8.07
173	INT114023	Positive_regulation of Transcription of Nos1	7	0.60	5.35	8.06
174	INT71381	Localization of Nos1	33	0.79	11.46	8.05
175	INT135443	Phosphorylation of Map2k1	11	0.80	2.44	8.01
176	INT171367	Phosphorylation of Map2k1	31	0.58	32.87	8
177	INT42707	Gene_expression of Tbce	24	0.65	12.92	7.93
178	INT76091	Positive_regulation of NOS3	48	0.61	18.4	7.92
179	INT82762	Positive_regulation of Positive_regulation of Mapk3	23	0.67	7.72	7.91
180	INT135441	Positive_regulation of Map2k1	15	0.67	6.6	7.87
181	INT172789	Regulation of Gene_expression of Nos3	15	0.53	16.23	7.86
182	INT25585	Positive_regulation of DNAH8	39	0.70	17.96	7.85
183	INT165036	Gene_expression of S100a9	38	0.77	38.33	7.84
184	INT57176	Positive_regulation of Dynll1	9	0.49	4.76	7.71
185	INT306287	Binding of TPPP	4	0.24	14.81	7.71
186	INT72372	Positive_regulation of Phosphorylation of Mapk3	30	0.67	13.6	7.69
187	INT91618	Positive_regulation of Phosphorylation of MAPK3	21	0.67	7.99	7.65
188	INT14207	Gene_expression of DNM2	20	0.67	5.76	7.64
189	INT65246	Negative_regulation of Nos3	36	0.50	25.65	7.62
190	INT1664	Gene_expression of Kitl	30	0.65	13.63	7.47
191	INT26462	Gene_expression of DNAH8	44	0.78	19.36	7.31
192	INT73181	Gene_expression of Hspb1	24	0.78	15.84	7.31
193	INT13348	Negative_regulation of Mastl	11	0.36	3.33	7.28
194	INT82610	Positive_regulation of SRC	53	0.67	26.89	7.27
195	INT132246	Negative_regulation of S100a8	19	0.43	22	7.25
196	INT74099	Negative_regulation of Dynll1	8	0.56	3.43	7.25
197	INT10478	Protein_catabolism of Alms1	25	0.47	12.95	7.19
198	INT145299	Negative_regulation of Jak3	25	0.48	17.66	7.13
199	INT16631	Negative_regulation of APC	46	0.57	30.53	7.11
200	INT83531	Gene_expression of KITLG	54	0.65	26	7.07