GOS:endoplasmic reticulum

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This page displays the top molecular interactions and top single events that were mentioned in the literature for endoplasmic reticulum. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for endoplasmic reticulum. They are ordered first by their pain relevance and then by number of times they were reported for endoplasmic reticulum. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Disease Relevance TM Confidence Documents Genes linked to endoplasmic reticulum Pain Relevance
1 INT221180 Binding of OPRM1 and Flna 0.22 0.09 1 1 12.65
2 INT206768 TP53 Positive_regulation of Ltp 5.83 0.01 2 1 10.21
3 INT98346 Negative_regulation of Binding of CPOX and PTGS1 2.91 0.10 1 1 6.54
4 INT251170 Clu Positive_regulation of Trpv1 2.61 0.28 1 1 6.49
5 INT296275 Binding of Dlg4 and Kcnip3 3.58 0.39 1 1 5.6
6 INT296484 Binding of Gria2 and GRIP1 4.52 0.04 1 2 4.59
7 INT51497 Cck Negative_regulation of Localization of Trim13 0 0.34 1 1 4.53
8 INT7022 Drd1a Positive_regulation of Npr1 0.26 0.05 6 1 4.32
9 INT107801 Ugt1a5 Positive_regulation of Localization of Prl 1 0.76 3 1 3.9
10 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 0.43 0.27 2 1 3.88
11 INT220623 Binding of Stat1 and Bace1 10.33 0.25 11 1 3.81
12 INT134284 Binding of OPRM1 and PLD2 0 0.52 1 1 3.72
13 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1.25 0.00 1 1 3.63
14 INT152035 Binding of HLA-A and MRAP 6.95 0.31 2 1 3.4
15 INT48162 RIMS3 Regulation of Localization of LTC4S 2.14 0.10 1 1 3.25
16 INT349584 Binding of Cyp2e1 and Aap 1.56 0.10 1 2 3.24
17 INT37162 Binding of Calca and Cckar 0.55 0.04 1 1 3.01
18 INT118158 Binding of Prkca and Prkcz 1.14 0.07 1 1 2.98
19 INT349589 Aap Positive_regulation of Cyp2e1 1.84 0.21 1 2 2.71
20 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 0.55 0.17 1 1 2.7
21 INT91350 Binding of Pla2g4a and RYBP 1.15 0.00 1 1 2.65
22 INT351444 Grin1 Positive_regulation of Gria2 1.5 0.22 1 1 2.64
23 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 0.86 0.38 1 2 2.63
24 INT104219 SCD Positive_regulation of Cnr1 2.67 0.00 1 1 2.54
25 INT42727 Binding of Oprm1 and Trim13 0 0.14 1 1 2.54
26 INT253988 Binding of Cd74 and Mif 6.57 0.36 1 2 2.52
27 INT156799 Gria1 Regulation of Grm8 1.29 0.11 1 1 2.45
28 INT147659 Prkce Positive_regulation of TRPV1 1.42 0.04 1 1 2.43
29 INT81657 Binding of CPOX and PTGS1 1.9 0.15 5 1 2.37
30 INT284860 Binding of Pdzd2 and Nav1 2.33 0.29 9 1 2.34
31 INT88730 Binding of OPRM1 and Mop3 0 0.00 1 1 2.34
32 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 0.08 0.00 1 1 2.31
33 INT321474 Binding of Slc6a2 and Ubqln1 0.8 0.00 1 3 2.27
34 INT321477 Binding of Ubqln1 and Flvcr2 0.81 0.00 1 3 2.26
35 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 0 0.01 1 1 2.26
36 INT85251 Chi3l1 Positive_regulation of Casp3 0 0.01 1 1 2.25
37 INT251164 Binding of Clu and Trpv1 0.44 0.19 1 1 2.23
38 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 0.92 0.24 1 1 2.2
39 INT146520 Tmem132a Regulation of Gene_expression of Fos 0.5 0.69 1 1 2.18
40 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 0.46 0.17 1 1 2.13
41 INT18593 Binding of Sst and Fdft1 0.08 0.11 2 2 2.12
42 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 0.53 0.33 1 1 2.1
43 INT51198 Positive_regulation of Binding of OPRM1 and PDYN 0.3 0.18 2 1 2.08
44 INT296277 Binding of Car2 and Kcnip3 1.09 0.18 5 1 2.06
45 INT53751 Positive_regulation of Cyp2e1 Positive_regulation of RYBP 0.89 0.14 1 1 1.98
46 INT113572 Binding of DMRT1 and OPRM1 0 0.01 1 1 1.9
47 INT129903 Nr1i2 Regulation of Cyp3a11 1.26 0.64 1 1 1.9
48 INT135582 Prok2 Positive_regulation of Localization of Prkce 1.02 0.06 1 1 1.87
49 INT169468 Binding of Egfr and Spink3 3.73 0.37 1 1 1.83
50 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 0.1 0.05 2 1 1.81
51 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 0.23 0.17 1 1 1.8
52 INT150456 Binding of Sort1 and Nts 0.64 0.45 3 1 1.79
53 INT115048 Kcnip3 Regulation of Gene_expression of Pdyn 0.71 0.27 2 1 1.78
54 INT167319 Binding of OPRM1 and PCSK2 0.63 0.22 1 1 1.77
55 INT167321 Binding of ENG and OPRM1 0.63 0.27 1 1 1.76
56 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 0 0.23 1 1 1.76
57 INT129953 Oprd1 Regulation of Cspg5 0.15 0.17 1 1 1.74
58 INT167765 Prkca Positive_regulation of Sigmar1 0.63 0.41 1 2 1.74
59 INT157524 Binding of GRM5 and OPRM1 0 0.36 1 1 1.74
60 INT92369 Binding of CYP2D6 and RYBP 0.15 0.25 1 1 1.73
61 INT139156 Binding of Gria1 and Gria2 0.64 0.23 1 2 1.72
62 INT169464 Akt1 Positive_regulation of Egfr 1.63 0.28 1 1 1.7
63 INT80199 Ngf Regulation of Transcription of Rab38 1.48 0.01 1 1 1.68
64 INT102447 Binding of CALCA and CALCRL 0.33 0.26 2 1 1.67
65 INT101926 Binding of Dio1 and Drd2 0.39 0.28 4 1 1.66
66 INT142437 Urb1 Negative_regulation of Faah 2.12 0.41 3 1 1.66
67 INT83093 IL1B Positive_regulation of BDKRB1 0.44 0.51 1 1 1.65
68 INT134742 Binding of OPRM1 and SV2A 0.18 0.33 1 2 1.64
69 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 0 0.12 1 2 1.62
70 INT32937 Binding of Pgrmc1 and Dtnb 0 0.20 1 2 1.61
71 INT109739 Binding of ITPA and Pcyt1b 0.72 0.16 1 1 1.6
72 INT195930 OPRM1 Regulation of Prkaca 0 0.01 1 1 1.59
73 INT326509 Binding of ACE and VWF 2.07 0.05 1 1 1.59
74 INT111076 Psen1 Regulation of Psenen 0.76 0.17 1 3 1.58
75 INT342993 PHEX Regulation of Protein_catabolism of SFTPA1 2.84 0.00 1 1 1.58
76 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 0.56 0.27 1 1 1.58
77 INT221182 Negative_regulation of Binding of OPRM1 and Flna 0 0.07 1 1 1.57
78 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 0.08 0.36 1 1 1.56
79 INT118159 Binding of Prkca and Prkcz Positive_regulation of Prkcz 0.58 0.02 1 1 1.54
80 INT100784 RYBP Positive_regulation of CYP3A4 0 0.44 1 1 1.54
81 INT66713 Binding of BDKRB1 and KNG1 0.39 0.22 2 1 1.53
82 INT63490 Negative_regulation of Dio1 Positive_regulation of Rtcd1 0.58 0.01 1 1 1.51
83 INT166676 Binding of PRKCA and UGT1A6 0 0.30 1 2 1.5
84 INT136844 Binding of Prkca and Nrgn 0 0.33 1 1 1.47
85 INT156008 Bcl2 Regulation of Localization of Aifm1 1.92 0.17 1 2 1.47
86 INT161870 OPRM1 Positive_regulation of Prkcg 0.12 0.01 1 1 1.47
87 INT201950 IFNA1 Positive_regulation of Binding of DPP4 and 2.17 0.12 1 1 1.47
88 INT123899 Binding of CYP3A4 and UGT2B7 0 0.52 1 2 1.46
89 INT141676 OPRM1 Positive_regulation of Ltp 0 0.04 1 1 1.46
90 INT201946 IFNA1 Positive_regulation of DPP4 2.16 0.17 1 1 1.46
91 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1.26 0.06 1 1 1.45
92 INT221242 Ros1 Positive_regulation of Prkca 0.39 0.02 1 1 1.44
93 INT111760 Dio1 Positive_regulation of Binding of Cpe and 0.34 0.04 1 1 1.44
94 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 0.17 0.37 1 1 1.44
95 INT128915 PENK Regulation of Gene_expression of OPRM1 0.07 0.22 1 1 1.43
96 INT111756 Dio1 Positive_regulation of Cpe 0.34 0.04 1 1 1.42
97 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1.65 0.05 1 1 1.42
98 INT29554 Ebp Positive_regulation of LH 0.12 0.40 2 2 1.41
99 INT298458 Binding of Calcrl and Adarb1 0.23 0.00 1 1 1.41
100 INT128914 COMT Regulation of OPRM1 0.07 0.39 1 1 1.39
101 INT116827 Binding of UCHL1 and TRPV1 0.88 0.41 1 1 1.39
102 INT29599 Binding of Cyp21a1 and Adarb1 0 0.01 1 1 1.38
103 INT158762 Binding of Vwf and Mthfr 1.85 0.05 1 2 1.37
104 INT279165 Calca Regulation of Gene_expression of Fdft1 0.41 0.02 1 2 1.37
105 INT51203 Binding of OPRK1 and OPRM1 0.3 0.29 2 1 1.36
106 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 0.54 0.16 1 1 1.35
107 INT158079 Binding of Esr1 and Gper 0.97 0.31 1 1 1.35
108 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 0.54 0.14 1 1 1.35
109 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 0.54 0.20 1 1 1.35
110 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 0.54 0.18 1 1 1.35
111 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 0.54 0.09 1 1 1.35
112 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 0.54 0.13 1 1 1.35
113 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 2.06 0.01 1 2 1.34
114 INT90221 Binding of CYP2D6 and Cyp1a2 0.09 0.03 1 2 1.31
115 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 0.81 0.01 1 1 1.31
116 INT314211 Ngf Positive_regulation of Gene_expression of Agtrap 1.15 0.04 1 1 1.3
117 INT201942 DPP4 Negative_regulation of CXCL10 0.9 0.33 1 1 1.3
118 INT148778 Binding of Usf1 and Rtn1 0.85 0.40 1 2 1.3
119 INT169297 TRPV1 Positive_regulation of EGFR 0.37 0.64 1 1 1.3
120 INT138211 Mzb1 Regulation of Sst 0.41 0.05 1 1 1.29
121 INT138212 Mzb1 Regulation of Localization of Sst 0.41 0.12 1 1 1.29
122 INT138213 Mzb1 Regulation of Localization of Tac1 0.41 0.01 1 1 1.29
123 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 0.69 0.06 1 1 1.28
124 INT138214 Mzb1 Regulation of Tac1 0.41 0.01 1 1 1.28
125 INT195929 Binding of OPRM1 and Prkaca 0.33 0.02 1 1 1.27
126 INT105295 WAS Regulation of PTGS1 0.13 0.02 1 1 1.27
127 INT86518 Ass1 Positive_regulation of Hmox2 0.08 0.03 1 2 1.27
128 INT73598 BAX Positive_regulation of Casp1 0.63 0.06 1 1 1.27
129 INT64077 Trpv1 Positive_regulation of Kcnma1 0.37 0.00 1 1 1.27
130 INT42580 CAT Negative_regulation of POMC 0.42 0.20 1 1 1.26
131 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 0.88 0.47 1 1 1.26
132 INT110542 SIGMAR1 Regulation of OPRM1 0.33 0.04 1 2 1.25
133 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 0.33 0.04 1 2 1.25
134 INT352269 Binding of Jund and Adora1 1.2 0.15 1 1 1.25
135 INT317569 Prkca Positive_regulation of Phosphorylation of Src 0 0.11 1 1 1.25
136 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1.09 0.06 1 1 1.24
137 INT167278 Binding of OPRM1 and REST 0.94 0.08 1 1 1.24
138 INT158545 Binding of Trpc3 and Jph2 0 0.55 1 1 1.24
139 INT136255 Tff3 Regulation of GRIA1 0.18 0.00 1 1 1.24
140 INT136258 Creb1 Regulation of GRIA1 0.18 0.26 1 1 1.23
141 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 0.61 0.27 2 1 1.22
142 INT310068 Pain1 Positive_regulation of Faah 1.3 0.03 1 1 1.22
143 INT7198 Magt1 Negative_regulation of Syt17 Positive_regulation of Ctsb 0 0.03 1 1 1.22
144 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1.24 0.29 1 1 1.22
145 INT59707 PSENEN Regulation of Negative_regulation of YY1 0.07 0.12 1 1 1.21
146 INT281373 Tcf21 Regulation of Fig4 0.67 0.03 1 1 1.2
147 INT83428 Binding of ADIPOQ and FRTS 2.02 0.18 3 1 1.19
148 INT281077 Binding of Gria2 and Gria3 0.35 0.24 2 1 1.19
149 INT281383 FSCN1 Positive_regulation of Fig4 0.44 0.02 1 1 1.19
150 INT184402 Binding of HLA-DRB4 and HLA-E 3.1 0.00 1 1 1.19
151 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 2.4 0.03 1 1 1.18
152 INT120205 Binding of App and Ern1 2.55 0.05 1 1 1.18
153 INT20929 Binding of Trim13 and Vas1 0 0.10 1 1 1.18
154 INT169082 Binding of GRIA1 and MOCOS 1.23 0.07 2 1 1.17
155 INT57823 Binding of Trim13 and Atxn2l 0.08 0.00 1 1 1.17
156 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 3 1.16
157 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 3.26 0.10 1 1 1.16
158 INT215648 Binding of Adora1 and Gabrd 0.06 0.03 1 1 1.16
159 INT117082 TNS3 Regulation of Ssr1 0 0.05 1 1 1.16
160 INT76256 Binding of Slc6a3 and Sigmar1 0 0.20 1 2 1.16
161 INT299985 BDKRB2 Regulation of Gene_expression of BDKRB1 0.75 0.21 1 1 1.16
162 INT137144 ITIH4 Regulation of OPRM1 1.13 0.20 1 1 1.16
163 INT125696 Binding of OPRM1 and SNRNP70 0.99 0.06 1 1 1.15
164 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 4.75 0.26 1 2 1.15
165 INT18596 Fdft1 Regulation of Localization of Acot1 0 0.06 1 2 1.14
166 INT262336 Binding of Abat and Tmem132a 1.39 0.00 1 1 1.14
167 INT123387 Binding of Camk2a and Gria2 0.32 0.13 1 1 1.14
168 INT197051 Binding of HLA-E and ATP8A1 6.52 0.00 1 1 1.14
169 INT321473 Binding of Slc6a3 and Ubqln1 0.41 0.00 1 3 1.13
170 INT7024 Regulation of Drd1a Positive_regulation of Npr1 0.07 0.04 1 1 1.13
171 INT222516 Binding of Calcrl and Ramp1 0.11 0.17 5 1 1.12
172 INT221183 Binding of OPRM1 and Mors1 0 0.00 1 1 1.12
173 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 0 0.15 1 1 1.11
174 INT285659 Binding of Faah and Mgll 0.99 0.15 1 1 1.11
175 INT113540 Binding of OPRM1 and Tac1 0.1 0.04 1 1 1.1
176 INT107266 Binding of HLA-DRB1 and TNF 1.41 0.29 1 1 1.1
177 INT317512 Binding of Oprm1 and Prkca 0.13 0.07 1 1 1.1
178 INT107265 Binding of HLA-DRB1 and ITGAL 1.41 0.01 1 1 1.1
179 INT323175 PRKCA Positive_regulation of Akt1 0 0.02 1 1 1.1
180 INT127133 Positive_regulation of OPRM1 Positive_regulation of Protein_catabolism of SUCLG2 0.2 0.20 1 1 1.1
181 INT74185 Cck Negative_regulation of Drd1a 0.1 0.30 1 1 1.1
182 INT264988 Binding of CYP2C19 and CYP3A4 0.72 0.18 1 2 1.09
183 INT44838 Pitpnm1 Negative_regulation of Th 0 0.02 1 1 1.09
184 INT90145 Binding of OPRL1 and OPRM1 0.31 0.27 2 1 1.08
185 INT14197 Pde2a Positive_regulation of Localization of Gh1 0 0.04 2 2 1.08
186 INT305734 Binding of Sort1 and Trpv1 0.5 0.01 1 1 1.08
187 INT28186 CYP2E1 Regulation of Positive_regulation of RYBP 0.33 0.04 1 1 1.08
188 INT264987 Binding of CYP2C9 and CYP3A4 0.71 0.19 1 2 1.08
189 INT37153 Binding of Mpz and Ptpn2 0.68 0.12 1 1 1.08
190 INT12684 Binding of Bcar3 and Trim13 0 0.03 1 1 1.08
191 INT81583 Cyp3a23/3a1 Positive_regulation of st 0 0.04 1 1 1.08
192 INT81580 Cyp3a23/3a1 Positive_regulation of Nudt14 0 0.01 1 1 1.08
193 INT296458 Binding of Gria2 and Pick1 1.86 0.24 3 1 1.07
194 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 0.42 0.32 1 1 1.07
195 INT96905 Plxna3 Regulation of Regulation of Prkce 0.71 0.18 1 2 1.07
196 INT77083 Das Negative_regulation of Cyp2e1 0.59 0.20 1 1 1.06
197 INT296460 Binding of Gria2 and Myo18a 1.49 0.01 1 1 1.06
198 INT56990 Cat Regulation of Efs 0 0.26 1 1 1.05
199 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 0 0.40 1 1 1.05
200 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1.05 0.00 1 1 1.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for endoplasmic reticulum. They are ordered first by their pain relevance and then by number of times they were reported in endoplasmic reticulum. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Disease Relevance TM Confidence Documents Pain Relevance
1 INT6580 Negative_regulation of Ptgs1 381.53 0.59 929 376.26
2 INT11624 Gene_expression of OPRM1 72.36 0.78 445 294.36
3 INT2391 Negative_regulation of PTGS1 207.62 0.59 501 205.6
4 INT4768 Positive_regulation of OPRM1 31.09 0.70 212 164.28
5 INT50674 Gene_expression of PTGS2 253.33 0.78 459 118.51
6 INT8413 Gene_expression of Ptgs1 110.17 0.78 248 108.58
7 INT940 Negative_regulation of Ptgs1 104.34 0.59 219 95.97
8 INT1639 Negative_regulation of OPRM1 13.86 0.59 107 90.37
9 INT73340 Negative_regulation of Faah 38.67 0.59 134 85.03
10 INT7528 Regulation of OPRM1 20.63 0.62 100 80.57
11 INT920 Localization of PLOD1 42.25 0.81 223 78.7
12 INT29708 Gene_expression of Gria1 56.36 0.78 177 77.37
13 INT15613 Negative_regulation of Ptgs2 71.08 0.59 160 65.08
14 INT39153 Positive_regulation of PTGS2 96.16 0.70 182 60.6
15 INT9196 Gene_expression of PTGS1 96.99 0.77 215 60.5
16 INT64159 Gene_expression of Prkca 34.65 0.78 90 55.97
17 INT52692 Gene_expression of Ptgs2 85.06 0.78 160 55.73
18 INT82650 Gene_expression of Bcl2 211.71 0.78 312 55.03
19 INT8071 Positive_regulation of Gria1 26.61 0.70 102 53.37
20 INT52611 Negative_regulation of Ptgs2 66.31 0.59 142 52.71
21 INT69484 Positive_regulation of Gene_expression of OPRM1 12.86 0.70 75 52.27
22 INT5858 Positive_regulation of Drd1a 4.51 0.69 66 51.73
23 INT50405 Negative_regulation of CYP3A4 53.65 0.59 238 51.51
24 INT53083 Gene_expression of Ptgs2 90.04 0.78 153 50.39
25 INT7093 Negative_regulation of CYP2B6 37.3 0.58 146 48.39
26 INT1564 Localization of OPRM1 8.03 0.80 41 44.67
27 INT8465 Regulation of Ptgs1 36.03 0.57 100 44.41
28 INT3933 Positive_regulation of PLOD1 30.76 0.70 128 42.03
29 INT57442 Phosphorylation of Prkca 31.58 0.70 98 41.04
30 INT55135 Positive_regulation of Gene_expression of PTGS2 80.32 0.70 137 38.46
31 INT77307 Gene_expression of Bcl2 319.77 0.77 399 38
32 INT56870 Gene_expression of CYP2D6 8.83 0.78 87 37.53
33 INT95646 Negative_regulation of Faah 25.61 0.59 63 36.78
34 INT77407 Regulation of Gene_expression of OPRM1 12.58 0.62 51 35.75
35 INT10796 Gene_expression of CYP2B6 30.14 0.77 131 35.27
36 INT40160 Positive_regulation of Adora1 26.36 0.70 74 33.03
37 INT20307 Positive_regulation of Cyp2e1 23.59 0.70 70 32.49
38 INT124860 Gene_expression of Bace1 157.11 0.78 330 31.65
39 INT86780 Positive_regulation of Hmox1 117.09 0.70 145 31.18
40 INT10797 Binding of CYP2D6 15.09 0.48 86 31.16
41 INT64164 Regulation of Prkca 10.44 0.62 34 30.99
42 INT49110 Regulation of Grip2 13.57 0.61 46 30.87
43 INT52690 Positive_regulation of Ptgs2 39.51 0.68 65 30.02
44 INT7664 Negative_regulation of Grip2 10.11 0.49 68 29.93
45 INT64918 Gene_expression of Gria2 29.95 0.74 108 29.67
46 INT72252 Gene_expression of Kcnma1 20.47 0.64 63 29.56
47 INT12751 Gene_expression of Pigm 22.42 0.58 91 29.2
48 INT651 Positive_regulation of PTGS1 37.27 0.69 93 29.18
49 INT49431 Phosphorylation of OPRM1 2.2 0.82 31 29.09
50 INT2389 Regulation of PTGS1 31.23 0.61 86 28.95
51 INT28361 Gene_expression of TP53 384.86 0.78 443 28.8
52 INT56525 Gene_expression of Gria2 23.15 0.75 74 28.6
53 INT52712 Negative_regulation of PRKCA 23.11 0.57 64 28.43
54 INT22211 Positive_regulation of CYP3A4 22 0.70 110 28.27
55 INT177581 Regulation of Fig4 39.26 0.41 113 27.75
56 INT12129 Gene_expression of CYP3A4 23.11 0.78 107 27.6
57 INT1638 Negative_regulation of PLOD1 21.69 0.59 92 26.61
58 INT56524 Gene_expression of Grip2 14.77 0.74 67 26.23
59 INT48832 Positive_regulation of Grip2 12.13 0.69 48 25.99
60 INT50490 Regulation of PTGS2 39.51 0.48 80 25.85
61 INT11159 Gene_expression of EGFR 548.93 0.78 698 25.69
62 INT2040 Positive_regulation of CYP2B6 34.3 0.69 95 25.6
63 INT9886 Gene_expression of Ptgs1 40.66 0.77 92 25.31
64 INT100423 Gene_expression of Bax 98.43 0.75 141 24.48
65 INT64076 Positive_regulation of Kcnma1 11.52 0.40 47 24.19
66 INT67585 Gene_expression of UGT2B7 2.33 0.78 52 24.13
67 INT101225 Positive_regulation of Gria2 28.1 0.64 62 23.93
68 INT917 Positive_regulation of Localization of PLOD1 8.53 0.69 51 22.87
69 INT76249 Gene_expression of Gria1 15.07 0.75 67 22.78
70 INT102112 Gene_expression of Prnp 209.32 0.78 440 22.5
71 INT21503 Binding of Ptgs1 15.6 0.48 45 22.29
72 INT39914 Negative_regulation of Cyp1a2 10.04 0.58 44 22
73 INT7573 Positive_regulation of Nr3c2 20 0.67 38 21.84
74 INT47859 Negative_regulation of Cyp2e1 16.92 0.59 41 21.72
75 INT49623 Negative_regulation of Gria1 12.4 0.59 39 21.59
76 INT52693 Positive_regulation of Gene_expression of Ptgs2 25.51 0.70 57 21.18
77 INT129987 Phosphorylation of Gria1 20.65 0.80 63 21.02
78 INT11161 Gene_expression of HLA-DRB1 75.33 0.78 121 20.96
79 INT73593 Gene_expression of BAX 147.81 0.76 173 20.94
80 INT17848 Binding of PTGS2 32.1 0.46 70 20.6
81 INT45840 Positive_regulation of Gene_expression of Ptgs1 16.07 0.50 35 20.49
82 INT79805 Phosphorylation of PRKCA 23.33 0.81 57 20.41
83 INT8765 Positive_regulation of Cyp3a23/3a1 22.28 0.67 63 20.39
84 INT7680 Regulation of Drd1a 4.52 0.45 27 18.86
85 INT56239 Positive_regulation of Rtn4 14.05 0.26 20 18.8
86 INT113399 Positive_regulation of Pla2g4a 33.83 0.67 36 18.78
87 INT636 Binding of MRAP 40.36 0.48 54 18.77
88 INT3060 Negative_regulation of Bche 46.75 0.59 94 18.51
89 INT93734 Positive_regulation of Gene_expression of Bcl2 61.95 0.70 76 18.46
90 INT68347 Negative_regulation of Cyp2d4 7.62 0.58 34 18.35
91 INT30197 Positive_regulation of Ubqln1 2.07 0.08 26 18.28
92 INT14724 Negative_regulation of CYP19A1 96.56 0.59 233 18.26
93 INT187513 Positive_regulation of Pla2g4a 34.09 0.62 5 18.22
94 INT9900 Positive_regulation of Vwf 51.85 0.69 80 18.13
95 INT9246 Positive_regulation of Cat 52.73 0.70 113 18.04
96 INT1642 Negative_regulation of Localization of PLOD1 10.67 0.58 40 17.95
97 INT14111 Positive_regulation of Cyp2c22 7.24 0.67 41 17.88
98 INT5922 Gene_expression of Rtn4 12.7 0.48 27 17.86
99 INT29709 Positive_regulation of Gene_expression of Gria1 9.43 0.69 36 17.83
100 INT50403 Negative_regulation of CYP2C19 8.97 0.59 55 17.79
101 INT80223 Positive_regulation of Hmox1 77.71 0.68 128 17.64
102 INT84464 Gene_expression of DPP4 56.15 0.78 101 17.53
103 INT51779 Gene_expression of Drd1a 11.18 0.66 46 17.51
104 INT101140 Negative_regulation of Tap1 9.08 0.50 7 17.46
105 INT50404 Negative_regulation of CYP1A2 8.61 0.59 49 17.35
106 INT22068 Binding of CALCRL 6.14 0.41 53 17.32
107 INT76406 Gene_expression of Hmox1 85.86 0.78 140 17.15
108 INT195831 Phosphorylation of Pla2g4a 34.43 0.74 15 17.14
109 INT7020 Negative_regulation of Drd1a 1.84 0.57 25 17.1
110 INT48690 Localization of Grip2 6.13 0.61 33 16.81
111 INT32753 Positive_regulation of Positive_regulation of OPRM1 3.3 0.62 19 16.73
112 INT170033 Positive_regulation of Gene_expression of Fig4 20.99 0.43 59 16.69
113 INT93361 Gene_expression of Trp53 175.35 0.78 208 16.65
114 INT117500 Gene_expression of Adipoq 67.79 0.74 90 16.58
115 INT1020 Negative_regulation of BCHE 44.86 0.59 109 16.4
116 INT49263 Binding of Grip2 9.86 0.41 31 16.38
117 INT59987 Gene_expression of BDKRB1 11.95 0.77 25 15.93
118 INT50618 Gene_expression of Dio1 17.37 0.74 48 15.91
119 INT111073 Gene_expression of Psen1 78.65 0.76 167 15.83
120 INT79458 Localization of Prkca 11.13 0.81 30 15.78
121 INT12950 Gene_expression of Cat 35.94 0.75 85 15.76
122 INT20336 Positive_regulation of CYP2E1 19.26 0.70 48 15.66
123 INT5859 Positive_regulation of Positive_regulation of Drd1a 2.05 0.55 20 15.61
124 INT15102 Gene_expression of Trim13 0.43 0.67 18 15.49
125 INT61172 Gene_expression of PRKCA 8.89 0.77 34 15.47
126 INT42810 Gene_expression of CALCRL 10.87 0.77 53 15.42
127 INT59929 Negative_regulation of CYP2C9 16.33 0.59 60 15.39
128 INT25872 Positive_regulation of Adora1 4.9 0.69 19 15.01
129 INT114510 Positive_regulation of Gria2 14.91 0.57 36 14.85
130 INT109031 Positive_regulation of Eif2ak3 21.11 0.69 44 14.72
131 INT9904 Gene_expression of CYP2E1 13.11 0.78 64 14.65
132 INT26975 Gene_expression of Adipoq 106.71 0.75 113 14.46
133 INT52696 Positive_regulation of Ptgs2 27.65 0.70 48 14.44
134 INT53080 Positive_regulation of Ptgs1 23.58 0.42 42 14.37
135 INT109511 Gene_expression of Bax 113.22 0.78 133 14.36
136 INT61864 Regulation of Gene_expression of Gria1 13.27 0.62 24 14.3
137 INT69743 Gene_expression of Hmox2 20.77 0.78 36 14.26
138 INT109034 Gene_expression of Eif2ak3 17.11 0.77 37 14.19
139 INT80228 Positive_regulation of Gene_expression of Hmox1 62.88 0.70 68 14.01
140 INT1873 Gene_expression of MRAP 31.75 0.76 51 13.92
141 INT91544 Gene_expression of CHI3L1 77.72 0.75 60 13.9
142 INT7997 Gene_expression of Ltc4s 34.28 0.76 51 13.8
143 INT6645 Positive_regulation of BDKRB1 12.17 0.66 14 13.79
144 INT49089 Gene_expression of Rab38 6.79 0.45 22 13.76
145 INT76863 Negative_regulation of Gene_expression of OPRM1 6.56 0.57 21 13.69
146 INT56651 Binding of HLA-DRB1 52.25 0.48 58 13.68
147 INT80883 Positive_regulation of Phosphorylation of OPRM1 1.03 0.69 13 13.65
148 INT12321 Binding of Nr3c2 5.44 0.46 19 13.46
149 INT64563 Gene_expression of UGT1A1 3.31 0.75 27 13.43
150 INT53747 Positive_regulation of Cyp2e1 29.03 0.70 34 13.39
151 INT18191 Negative_regulation of Cyp3a23/3a1 10.21 0.57 48 13.38
152 INT76469 Positive_regulation of Gene_expression of Prkca 7.9 0.46 18 13.36
153 INT49538 Binding of Gria1 2.66 0.47 22 13.35
154 INT69569 Positive_regulation of Prnp 96.31 0.70 175 13.34
155 INT86383 Negative_regulation of EGFR 173.94 0.59 258 13.32
156 INT59665 Positive_regulation of Ugt1a6 7.24 0.69 24 13.25
157 INT101147 Gene_expression of Uchl1 14.73 0.76 31 13.22
158 INT80222 Negative_regulation of Bcl2 69.16 0.58 82 13.18
159 INT6749 Binding of Dio1 4.41 0.38 25 13.07
160 INT28014 Localization of Cyp3a23/3a1 9.8 0.77 34 12.96
161 INT116528 Gene_expression of HMOX1 86.13 0.78 106 12.8
162 INT78797 Regulation of Tmem132a 3.61 0.45 8 12.73
163 INT28420 Gene_expression of Ptgds 31.72 0.78 59 12.67
164 INT3040 Gene_expression of MIA3 53.61 0.24 81 12.62
165 INT879 Localization of Fdft1 1.11 0.59 16 12.59
166 INT63104 Negative_regulation of CALCRL 13.62 0.37 29 12.42
167 INT59080 Negative_regulation of Gene_expression of PTGS2 22.92 0.58 55 12.39
168 INT27507 Positive_regulation of Dio1 3.43 0.44 23 12.11
169 INT117502 Positive_regulation of Adipoq 40.43 0.63 70 12.03
170 INT111948 Positive_regulation of Gria1 7.55 0.61 23 12.03
171 INT49087 Positive_regulation of Rab38 8.01 0.00 20 12
172 INT149985 Gene_expression of Tlr9 29.83 0.75 32 11.86
173 INT7682 Binding of Drd1a 1.8 0.48 22 11.83
174 INT81640 Positive_regulation of Gene_expression of Bcl2 84.58 0.69 106 11.63
175 INT20457 Regulation of Ptgs1 11.63 0.48 23 11.56
176 INT19795 Positive_regulation of EGFR 103.69 0.70 161 11.55
177 INT787 Localization of Ptgs1 12.36 0.80 31 11.55
178 INT148639 Gene_expression of Uchl1 16.76 0.59 30 11.54
179 INT1735 Gene_expression of HSD11B1 257.87 0.75 199 11.5
180 INT72221 Localization of PRKCA 1.23 0.81 17 11.47
181 INT173272 Phosphorylation of Fig4 13.85 0.48 45 11.42
182 INT53082 Positive_regulation of Gene_expression of Ptgs2 25.39 0.64 47 11.39
183 INT13338 Regulation of Sigmar1 2.91 0.57 22 11.35
184 INT270238 Localization of Pla2g4a 17.99 0.72 1 11.35
185 INT10798 Positive_regulation of CYP2D6 5.82 0.56 24 11.31
186 INT17199 Negative_regulation of Cspg5 3.07 0.56 7 11.26
187 INT5464 Regulation of CALCRL 4.2 0.16 24 11.19
188 INT6748 Regulation of Dio1 2.63 0.45 15 11.18
189 INT88650 Negative_regulation of Prkce 11.93 0.57 13 11.16
190 INT71189 Gene_expression of Cyp1a2 11.39 0.78 24 11.12
191 INT30193 Localization of Ubqln1 1.69 0.12 20 11.09
192 INT62580 Gene_expression of Cyp2e1 15.4 0.78 31 11.08
193 INT57069 Regulation of Gria2 10.11 0.44 28 11.06
194 INT192967 Gene_expression of Hp 8.06 0.43 14 11.01
195 INT15305 Positive_regulation of Mtor 8.28 0.67 51 11
196 INT52918 Positive_regulation of Prkca 1.67 0.64 13 11
197 INT111223 Positive_regulation of HMOX1 39.14 0.70 47 10.92
198 INT273123 Binding of Hp 3.56 0.25 1 10.9
199 INT52916 Negative_regulation of Prkca 2.4 0.54 9 10.79
200 INT83886 Negative_regulation of HMOX2 11.69 0.43 27 10.78
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