GOS:lysosome

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This page displays the top molecular interactions and top single events that were mentioned in the literature for lysosome. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for lysosome. They are ordered first by their pain relevance and then by number of times they were reported for lysosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Disease Relevance TM Confidence Documents Genes linked to lysosome Pain Relevance
1 INT137918 Oprm1 Positive_regulation of Pdgfrb 0 0.41 1 1 3.31
2 INT7190 Syt17 Positive_regulation of Ctsb 0 0.16 1 3 3.23
3 INT37162 Binding of Calca and Cckar 0.55 0.04 1 1 3.01
4 INT150632 Ea1 Negative_regulation of Mpo 1.55 0.17 1 1 2.9
5 INT103669 Hps4 Positive_regulation of Mors1 0 0.01 1 2 2.7
6 INT253988 Binding of Cd74 and Mif 6.57 0.36 1 2 2.52
7 INT14687 Binding of Penk and Ppt1 0 0.41 1 3 2.46
8 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 0 0.10 1 3 2.25
9 INT18197 Ghrh Positive_regulation of Localization of Ggh 0 0.46 4 1 2.23
10 INT279359 Binding of ADA and TNF 2.61 0.20 1 1 1.91
11 INT43447 Binding of H3 and Hps4 0 0.07 1 2 1.82
12 INT302646 ARSA Positive_regulation of TGFB1 0.52 0.10 1 1 1.76
13 INT30134 Binding of TPP1 and S100A9 0.74 0.13 1 2 1.69
14 INT102447 Binding of CALCA and CALCRL 0.33 0.26 2 1 1.67
15 INT288731 Binding of Got1 and Gpt 1.25 0.23 1 1 1.61
16 INT44505 Mt1a Positive_regulation of Mt1a Positive_regulation of Prl 0 0.19 1 1 1.48
17 INT44504 Mt1a Positive_regulation of Prl 0 0.37 1 1 1.48
18 INT104972 MITF Regulation of Transcription of TYR 0.35 0.20 1 1 1.45
19 INT31391 Binding of PRCP and Abpa 0.16 0.03 1 1 1.42
20 INT298458 Binding of Calcrl and Adarb1 0.23 0.00 1 1 1.41
21 INT169163 Binding of Calca and Ctbs 0.51 0.00 1 1 1.4
22 INT299311 Binding of RPTOR and RICTOR 0.21 0.38 1 1 1.4
23 INT167528 Ppt1 Negative_regulation of Gene_expression of Tac4 0.49 0.06 1 3 1.39
24 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 0.49 0.26 1 3 1.38
25 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 0.73 0.49 2 1 1.36
26 INT115272 Neu1 Positive_regulation of Coq10a 0.41 0.43 1 1 1.35
27 INT115271 Neu1 Positive_regulation of Coq10a 0.41 0.01 1 1 1.35
28 INT299281 Binding of RPTOR and MAPKAP1 0.21 0.23 1 1 1.3
29 INT86518 Ass1 Positive_regulation of Hmox2 0.08 0.03 1 1 1.27
30 INT70181 PRCP Positive_regulation of FOS 0.36 0.58 1 1 1.26
31 INT42580 CAT Negative_regulation of POMC 0.42 0.20 1 1 1.26
32 INT7200 Reg3b Negative_regulation of Syt17 Positive_regulation of Ctsb 0 0.01 1 3 1.22
33 INT7198 Magt1 Negative_regulation of Syt17 Positive_regulation of Ctsb 0 0.03 1 3 1.22
34 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 0 0.03 1 3 1.21
35 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 0 0.03 1 3 1.21
36 INT222516 Binding of Calcrl and Ramp1 0.11 0.17 5 1 1.12
37 INT107567 Hps4 Positive_regulation of Localization of Il1b 0.09 0.01 1 2 1.08
38 INT305734 Binding of Sort1 and Trpv1 0.5 0.01 1 1 1.08
39 INT172757 Rnpep Positive_regulation of Hps4 0 0.00 1 2 1.08
40 INT107564 Hps4 Regulation of Localization of Il1b 0.1 0.01 1 2 1.07
41 INT7199 Syt17 Regulation of Syt17 Positive_regulation of Ctsb 0 0.02 1 3 1.05
42 INT56990 Cat Regulation of Efs 0 0.26 1 1 1.05
43 INT107566 Penk Regulation of Hps4 0.1 0.00 1 2 1.04
44 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 0 0.13 1 3 1.04
45 INT7201 Syt17 Negative_regulation of Syt17 Positive_regulation of Ctsb 0 0.03 1 3 1.04
46 INT107565 Hps4 Regulation of Mtr 0.1 0.00 1 2 1.04
47 INT352295 Binding of P2RY2 and Agtr1a 0.08 0.01 1 1 1.02
48 INT153727 Sds Negative_regulation of RYBP Positive_regulation of Slc17a5 0.68 0.02 1 2 1.01
49 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 0.13 0.07 1 1 0.99
50 INT61637 Binding of P2ry2 and Gtpbp4 0.1 0.02 1 1 0.99
51 INT38579 Binding of POMC and Hps4 0.32 0.00 1 2 0.99
52 INT130232 Binding of Cat and Sod1 0.3 0.35 1 1 0.98
53 INT90385 EXTL3 Regulation of Ctsl 1.1 0.00 1 1 0.98
54 INT153729 RYBP Positive_regulation of Slc17a5 0.65 0.02 1 2 0.97
55 INT25272 Binding of Ggh and Ghrh 0 0.22 1 1 0.97
56 INT219279 Ctss Positive_regulation of Gene_expression of Fam64a 1.39 0.06 1 2 0.96
57 INT219273 Fam64a Positive_regulation of Gene_expression of Ctss 1.39 0.06 1 2 0.96
58 INT206857 Binding of Calca and Calcrl 1.9 0.37 4 1 0.95
59 INT302309 Hps4 Positive_regulation of Cia1 1.34 0.01 1 2 0.95
60 INT70802 Ngf Regulation of Ppt1 0.39 0.21 1 3 0.93
61 INT161769 Cck Regulation of Cckar 0.53 0.27 1 1 0.92
62 INT124742 ARSA Positive_regulation of Localization of CSF2 0.15 0.10 1 1 0.91
63 INT141965 Binding of ADM and CALCRL 3.6 0.33 5 1 0.89
64 INT305742 Binding of Sort1 and Gtf3a 0.64 0.01 1 1 0.88
65 INT124743 ARSA Negative_regulation of PTGER2 0.15 0.03 1 1 0.85
66 INT194856 Positive_regulation of Adora2b Negative_regulation of Positive_regulation of Mmp13 0.73 0.01 1 1 0.85
67 INT238642 Binding of TNF and Ada 0.86 0.03 1 1 0.84
68 INT335644 CTSB Positive_regulation of F2RL1 2.58 0.02 1 1 0.82
69 INT296829 USE1 Regulation of CASP4 0.17 0.01 1 1 0.81
70 INT141605 Gene_expression of Ctsl Positive_regulation of Positive_regulation of MET 0 0.34 1 1 0.8
71 INT127383 Neo1 Regulation of Localization of Mpo 0.7 0.14 1 1 0.79
72 INT63588 Aap Positive_regulation of Positive_regulation of Got1 0.6 0.31 1 1 0.79
73 INT209043 Binding of Fn1 and Slc11a1 1.91 0.03 3 1 0.78
74 INT141963 Binding of CALCRL and RAMP1 0.81 0.43 2 1 0.78
75 INT296787 Tbrs1 Positive_regulation of Gene_expression of Tlr9 1.37 0.06 1 1 0.78
76 INT168457 Sult1a1 Positive_regulation of Cat 1.56 0.15 1 1 0.78
77 INT346133 RAMP2 Regulation of ADM 2.06 0.13 1 1 0.78
78 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1.37 0.03 1 1 0.77
79 INT266108 Binding of COMT and HPS1 1.21 0.23 1 1 0.74
80 INT19577 Gabrg1 Negative_regulation of Got1 0.16 0.04 1 1 0.74
81 INT63589 Binding of Got1 and Gpt 0.56 0.36 1 1 0.74
82 INT44502 Regulation of Mt1a Positive_regulation of Prl 0 0.14 1 1 0.74
83 INT162241 Binding of COL7A1 and MMP13 0.86 0.03 2 1 0.73
84 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1.8 0.03 1 1 0.73
85 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 0.73 0.65 1 1 0.73
86 INT228499 Binding of FAS and Fasl 2.75 0.15 1 1 0.73
87 INT31389 Negative_regulation of Binding of PRCP and Abpa 0.09 0.02 1 1 0.72
88 INT101675 Bcl2l11 Regulation of Localization of Ggh 0 0.03 1 1 0.72
89 INT216654 Binding of P2ry2 and DRGX 1.59 0.01 1 1 0.71
90 INT31390 Positive_regulation of Binding of PRCP and Abpa 0.08 0.04 1 1 0.71
91 INT239538 Binding of CXCR4 and CALCRL 0.35 0.00 1 1 0.71
92 INT84605 Binding of Avp and Avp Regulation of Aqp2 0 0.07 1 1 0.7
93 INT121697 IL4I1 Positive_regulation of Gene_expression of MMP3 0.27 0.06 1 1 0.7
94 INT51705 Binding of Penk and Naga 0.08 0.19 1 1 0.69
95 INT102762 Binding of POMC and TYR 0.35 0.12 1 1 0.69
96 INT302642 Binding of ARSA and TGFB1 0.28 0.05 1 1 0.68
97 INT125543 Arsa Negative_regulation of Phosphorylation of Nfkbia 0.52 0.00 1 2 0.68
98 INT299282 PTPN3 Negative_regulation of Positive_regulation of RPTOR 0.48 0.07 1 1 0.67
99 INT109718 Tac1 Negative_regulation of Mpo 0.81 0.25 1 1 0.67
100 INT296790 Tlr9 Regulation of Bax 0.76 0.14 1 1 0.65
101 INT209063 Slc11a1 Positive_regulation of Il17a 0.4 0.11 1 1 0.65
102 INT216644 Binding of P2ry1 and P2ry2 0.55 0.24 1 1 0.64
103 INT333544 CTSB Regulation of Protein_catabolism of APP 0.53 0.01 1 1 0.62
104 INT94075 ARSA Negative_regulation of Gene_expression of IL4 0.26 0.28 1 1 0.62
105 INT13618 Acyp2-ps1 Negative_regulation of Localization of Ggh 0 0.07 1 1 0.62
106 INT79210 Hps4 Negative_regulation of Mme 0 0.00 1 2 0.62
107 INT333543 CTSB Regulation of APP 0.53 0.01 1 1 0.62
108 INT36320 PDYN Negative_regulation of Ctsb 0 0.00 1 3 0.61
109 INT77120 Pomc Regulation of HYAL1 0 0.01 1 1 0.61
110 INT31392 Binding of PRCP and Gpr37 0.1 0.01 1 1 0.6
111 INT178087 EDN1 Positive_regulation of MMP13 1.58 0.23 2 1 0.59
112 INT316674 Binding of CRP and SFTPD 2.02 0.16 1 1 0.59
113 INT202160 Binding of ARSD and CSF1R 1.69 0.16 1 1 0.59
114 INT250054 Positive_regulation of Binding of Gpr143 and Spdya 0.52 0.04 1 1 0.59
115 INT125546 Arsa Negative_regulation of Gene_expression of PTGS2 0.53 0.00 1 2 0.58
116 INT345303 MMP15 Positive_regulation of MMP13 1.18 0.00 1 1 0.58
117 INT116787 CALCRL Regulation of Trpv1 0 0.01 1 1 0.56
118 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 0 0.00 1 1 0.56
119 INT195773 Binding of Cd74 and Mif 2.78 0.25 2 1 0.55
120 INT131316 Tnf Positive_regulation of Mpo 0.65 0.29 1 1 0.55
121 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 0.28 0.08 1 1 0.55
122 INT18116 NPC1 Negative_regulation of Binding of NPC1 and Oprd1 0 0.13 1 1 0.54
123 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 0.54 0.01 1 1 0.54
124 INT13191 FPR1 Positive_regulation of Localization of GUSB 0 0.31 1 1 0.53
125 INT13192 FPR1 Positive_regulation of Localization of LRBA 0 0.47 1 1 0.53
126 INT253767 Binding of Hmgb1 and Tlr9 1.78 0.12 2 1 0.52
127 INT144128 Binding of Gja1 and Prkce 0.5 0.40 1 1 0.52
128 INT275388 Binding of Lamp1 and Cxcr4 1.45 0.01 1 3 0.52
129 INT1006 Sst Negative_regulation of Ggh 0 0.24 1 1 0.52
130 INT144130 Binding of Gja1 and Prkcg 0.5 0.48 1 1 0.52
131 INT275387 Binding of Lamp1 and Ccr5 1.45 0.01 1 3 0.52
132 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 0.29 0.04 1 1 0.51
133 INT346205 Binding of CD74 and TPPP 0.87 0.02 1 1 0.51
134 INT37583 Naga Regulation of Odc1 0 0.20 1 1 0.51
135 INT248135 Binding of IDS and ACCS 1.12 0.09 1 1 0.51
136 INT66188 Binding of ADRB2 and CDSN 0 0.01 1 1 0.51
137 INT334901 LDLR Positive_regulation of Crp 1.48 0.00 1 1 0.51
138 INT302647 ARSA Positive_regulation of TGFBR1 0.29 0.03 1 1 0.51
139 INT23091 Tnf Positive_regulation of Localization of Ggh 0.15 0.05 1 1 0.5
140 INT292873 Binding of Fas and Fasl 15.74 0.26 5 1 0.49
141 INT14992 FPR1 Positive_regulation of Localization of MPO 1.1 0.56 2 1 0.49
142 INT17622 Ass1 Positive_regulation of Lhb 1.22 0.02 1 1 0.49
143 INT288729 Positive_regulation of Binding of Got1 and Gpt 0.61 0.25 1 1 0.49
144 INT47226 Asap1 Regulation of Hps4 0.18 0.10 1 2 0.49
145 INT31531 Mif-ps1 Regulation of TYR 0 0.11 1 1 0.49
146 INT118485 CST3 Regulation of CTSH 0 0.36 1 2 0.49
147 INT302643 ARSA Positive_regulation of Localization of TGFB1 0.12 0.08 1 1 0.49
148 INT165078 Binding of CTSB and Notch1 1.08 0.00 1 1 0.48
149 INT173597 Negative_regulation of Binding of MMP2 and Mmp13 0.83 0.14 1 1 0.48
150 INT88889 Binding of HSPG2 and CALCRL 0 0.00 1 1 0.48
151 INT58633 Negative_regulation of Il1f5 Negative_regulation of Mpo 0.98 0.15 1 1 0.48
152 INT173595 Binding of MMP2 and Mmp13 0.83 0.12 1 1 0.48
153 INT114593 Il1b Positive_regulation of Gene_expression of Ppt1 0.06 0.05 1 3 0.48
154 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 0.09 0.07 1 1 0.48
155 INT173596 Binding of MMP3 and Mmp13 0.84 0.06 1 1 0.48
156 INT58634 Negative_regulation of Il1 Negative_regulation of Mpo 0.98 0.20 1 1 0.47
157 INT70180 Binding of PRCP and NCOR2 Positive_regulation of Positive_regulation of FOS 0.08 0.06 1 1 0.47
158 INT70183 Binding of PRCP and NCOR2 0.08 0.04 1 1 0.46
159 INT291018 Binding of NSF and USE1 0.98 0.03 1 1 0.46
160 INT195774 Binding of MIF and Cd74 1.15 0.02 1 1 0.46
161 INT177440 Binding of HPSE and Gnrh1 1.82 0.00 1 1 0.45
162 INT222923 Negative_regulation of Pde4a Negative_regulation of Positive_regulation of Mpo 0.59 0.04 1 1 0.45
163 INT345305 MMP14 Positive_regulation of MMP13 0.33 0.00 1 1 0.45
164 INT224686 S100a4 Positive_regulation of Gene_expression of Mmp13 0.85 0.05 1 1 0.45
165 INT191489 Positive_regulation of P2ry2 Negative_regulation of Positive_regulation of Trpv1 0.08 0.03 1 1 0.44
166 INT12702 Regulation of Binding of FPR1 and GUSB 0.18 0.43 1 1 0.44
167 INT241912 Cat Positive_regulation of Ros1 0.76 0.03 1 1 0.44
168 INT296827 Binding of BGN and USE1 0 0.01 1 1 0.44
169 INT209049 Slc11a1 Positive_regulation of Localization of Il12a 0.09 0.04 1 1 0.44
170 INT12703 Binding of FPR1 and GUSB 0.18 0.36 1 1 0.44
171 INT279360 ADA Negative_regulation of Gene_expression of IFNG 0.51 0.06 1 1 0.44
172 INT8356 Binding of YY1 and Smpd1 0 0.32 1 1 0.43
173 INT270043 Binding of Ldlr and Hdl1 2.3 0.01 1 1 0.43
174 INT321046 Anpep Regulation of Negative_regulation of Hps4 0.25 0.02 1 2 0.43
175 INT63152 Ppt1 Regulation of Gene_expression of Pd 0 0.01 1 3 0.43
176 INT56577 Mt1a Positive_regulation of Localization of Gnrh1 0 0.04 1 1 0.43
177 INT90079 Ass1 Positive_regulation of Casp1 0.99 0.02 1 1 0.43
178 INT296831 Binding of CASP4 and USE1 0 0.01 1 1 0.43
179 INT316121 IL10 Regulation of Gene_expression of HLA-DRA 0.46 0.09 1 1 0.42
180 INT244421 Binding of DST and Ctss 0.42 0.02 1 2 0.41
181 INT327562 Binding of MCS and AKR1B10 0.5 0.00 1 1 0.41
182 INT114601 Il1b Positive_regulation of Transcription of Ppt1 0.1 0.35 1 3 0.41
183 INT92744 Binding of ADRB2 and NF2 0.1 0.00 1 1 0.41
184 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 0.8 0.00 1 1 0.41
185 INT91545 Binding of HTR1B and CALCRL 0.09 0.01 1 1 0.41
186 INT13620 Acyp2-ps1 Regulation of Localization of Ggh 0 0.07 1 1 0.41
187 INT335643 CTSB Positive_regulation of PAR4 1.3 0.01 1 1 0.41
188 INT37584 Naga Positive_regulation of Odc1 0 0.51 1 1 0.4
189 INT273893 ARSA Positive_regulation of HSD11B1 0.61 0.00 1 1 0.4
190 INT75149 Binding of CALCRL and ZNF594 0.08 0.00 1 1 0.39
191 INT75150 ZNF594 Negative_regulation of Binding of CALCRL and ZNF594 0.08 0.00 1 1 0.39
192 INT181862 Binding of MPO and PRTN3 1.18 0.16 2 1 0.38
193 INT136821 Binding of CALCRL and OGFR 0.36 0.02 1 1 0.38
194 INT296828 USE1 Regulation of Gene_expression of BGN 0.17 0.01 1 1 0.37
195 INT316675 Binding of CALR and SFTPD 0.96 0.35 1 1 0.37
196 INT277353 VEGFA Regulation of Mtor 1.11 0.02 1 1 0.37
197 INT296826 USE1 Regulation of Gene_expression of CASP4 0.17 0.02 1 1 0.37
198 INT277354 Gene_expression of VEGFA Regulation of Mtor 1.1 0.02 1 1 0.37
199 INT70185 PRCP Positive_regulation of Gene_expression of FOS 0.1 0.05 1 1 0.37
200 INT299288 AKT1 Positive_regulation of RPTOR 0.05 0.34 1 1 0.36

Single Events

The table below shows the top 100 pain related interactions that have been reported for lysosome. They are ordered first by their pain relevance and then by number of times they were reported in lysosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Disease Relevance TM Confidence Documents Pain Relevance
1 INT2604 Positive_regulation of Got1 154.78 0.70 223 49.51
2 INT14575 Positive_regulation of Ppt1 9.97 0.70 60 27.4
3 INT129956 Gene_expression of MMP13 60.48 0.72 145 26.98
4 INT13415 Positive_regulation of Hpse 24.9 0.70 58 25.53
5 INT93626 Gene_expression of Fasl 115.24 0.75 118 25.11
6 INT58301 Positive_regulation of Mpo 80.19 0.70 87 23.99
7 INT37889 Gene_expression of P2ry2 26.01 0.65 75 23.8
8 INT4890 Gene_expression of Ppt1 8.93 0.77 51 21.83
9 INT4894 Transcription of Ppt1 5.93 0.67 34 21.06
10 INT116282 Gene_expression of Mmp13 45.4 0.75 83 20.18
11 INT6993 Negative_regulation of Mpo 61.83 0.59 72 19.51
12 INT76924 Positive_regulation of Slc17a5 41.21 0.70 71 19.31
13 INT4420 Positive_regulation of GOT1 88.4 0.64 103 18.38
14 INT61519 Gene_expression of Mpo 89.29 0.78 112 18.22
15 INT9246 Positive_regulation of Cat 52.73 0.70 113 18.04
16 INT22068 Binding of CALCRL 6.14 0.41 53 17.32
17 INT3206 Positive_regulation of Got1 19.36 0.69 39 17.02
18 INT1000 Localization of Ggh 2.74 0.75 31 16.41
19 INT2480 Negative_regulation of Got1 14.47 0.51 43 16.09
20 INT14152 Gene_expression of Slc17a5 20.01 0.61 46 15.9
21 INT12950 Gene_expression of Cat 35.94 0.75 85 15.76
22 INT42810 Gene_expression of CALCRL 10.87 0.77 53 15.42
23 INT30440 Gene_expression of Hps4 2.39 0.29 15 15.31
24 INT1284 Negative_regulation of Mmp13 36.21 0.57 20 14.91
25 INT32802 Negative_regulation of Ada 4.03 0.57 21 14.87
26 INT18430 Positive_regulation of Hps4 0.81 0.24 14 14.82
27 INT61635 Positive_regulation of P2ry2 12.08 0.56 35 14.68
28 INT4726 Negative_regulation of PPT1 10.09 0.57 15 14.17
29 INT10585 Localization of NAGLU 23.32 0.80 53 12.75
30 INT123779 Positive_regulation of MMP13 24.3 0.65 42 12.45
31 INT63104 Negative_regulation of CALCRL 13.62 0.37 29 12.42
32 INT104569 Gene_expression of Aqp2 16.56 0.60 23 12.23
33 INT93620 Positive_regulation of Gene_expression of Fasl 59.45 0.66 51 12.04
34 INT16772 Gene_expression of MPO 90.98 0.78 81 11.9
35 INT149985 Gene_expression of Tlr9 29.83 0.75 32 11.86
36 INT30236 Negative_regulation of Hps4 1.03 0.15 8 11.4
37 INT5464 Regulation of CALCRL 4.2 0.16 24 11.19
38 INT15305 Positive_regulation of Mtor 8.28 0.67 51 11
39 INT3851 Gene_expression of Got1 29.15 0.65 58 10.52
40 INT15888 Positive_regulation of Nbr1 35.76 0.69 42 10.48
41 INT6431 Positive_regulation of Ass1 8.08 0.24 36 10.43
42 INT20166 Negative_regulation of Mtor 10.64 0.56 32 10.25
43 INT79720 Positive_regulation of Cat 31.81 0.70 57 10.11
44 INT49474 Gene_expression of Hpse 20.11 0.55 24 10.03
45 INT11238 Positive_regulation of ADA 39.7 0.70 33 9.98
46 INT5465 Positive_regulation of CALCRL 7.24 0.49 25 9.8
47 INT120509 Gene_expression of Cat 50.9 0.77 65 9.75
48 INT140191 Positive_regulation of Gene_expression of Mmp13 13.47 0.67 25 9.71
49 INT105816 Gene_expression of P2RY2 16.47 0.78 53 9.67
50 INT15307 Regulation of Mtor 4.7 0.48 27 9.34
51 INT47301 Gene_expression of Ctsl 7.72 0.76 27 9.32
52 INT18429 Localization of Hps4 1.23 0.31 8 9.01
53 INT13010 Gene_expression of TYR 14.81 0.65 38 8.84
54 INT29411 Positive_regulation of ADRB2 5.42 0.65 13 8.78
55 INT3622 Regulation of CTSB 16.08 0.58 34 8.76
56 INT129962 Positive_regulation of Gene_expression of MMP13 20.74 0.65 41 8.54
57 INT24651 Positive_regulation of Transcription of Ppt1 2.88 0.47 12 8.42
58 INT127378 Localization of Mpo 26.36 0.78 21 8.28
59 INT56223 Positive_regulation of MPO 43 0.70 35 8.2
60 INT4663 Positive_regulation of Ada 9.48 0.69 17 7.93
61 INT5164 Negative_regulation of Ldlr 55.01 0.58 83 7.87
62 INT87623 Gene_expression of PPT1 5.32 0.75 9 7.65
63 INT5431 Gene_expression of Glb1 6.53 0.75 23 7.58
64 INT7168 Positive_regulation of Ctsb 0.3 0.70 9 7.58
65 INT43441 Binding of Hps4 0.46 0.24 7 7.43
66 INT7883 Binding of ADRB2 5.49 0.47 18 7.37
67 INT15887 Gene_expression of Nbr1 23.91 0.77 39 7.34
68 INT76253 Positive_regulation of P2RY2 13.99 0.70 29 7.33
69 INT153794 Gene_expression of Ctsk 24.99 0.77 51 7.28
70 INT327801 Positive_regulation of Gene_expression of Aqp2 7.67 0.44 6 7.24
71 INT4228 Gene_expression of CAT 20.62 0.75 50 7.18
72 INT78199 Gene_expression of Neu1 62.88 0.75 65 7.16
73 INT5774 Regulation of Ppt1 4.97 0.60 22 7.1
74 INT10863 Positive_regulation of Ldlr 31.06 0.68 45 7.05
75 INT27916 Gene_expression of Mt1a 4.4 0.47 6 7.04
76 INT1973 Positive_regulation of NAGLU 14.78 0.65 36 7
77 INT99942 Positive_regulation of Fasl 32.61 0.68 37 6.92
78 INT95466 Regulation of P2ry2 3.66 0.56 23 6.86
79 INT31911 Regulation of Hps4 2.16 0.19 5 6.83
80 INT4208 Regulation of Got1 6.72 0.44 23 6.62
81 INT207892 Binding of Tlr9 26.66 0.46 35 6.61
82 INT87775 Phosphorylation of Gja1 2.75 0.82 13 6.56
83 INT250050 Gene_expression of Gpr143 5.76 0.48 1 6.53
84 INT112459 Localization of Gba 1.45 0.80 12 6.4
85 INT168383 Positive_regulation of Mmp13 17.9 0.67 27 6.27
86 INT11826 Positive_regulation of LDLR 45.09 0.62 62 6.21
87 INT88245 Gene_expression of Slc11a1 18.86 0.53 42 6.2
88 INT154229 Gene_expression of ARSD 12.5 0.57 22 6.19
89 INT181017 Gene_expression of Ctss 9.82 0.65 6 6.19
90 INT57562 Gene_expression of GLA 24.62 0.77 52 6.14
91 INT250048 Positive_regulation of Gpr143 5.85 0.43 12 6.1
92 INT113961 Regulation of PPT1 3.87 0.26 6 6.09
93 INT35780 Positive_regulation of Mt1a 4.9 0.55 9 6.08
94 INT17551 Positive_regulation of Gene_expression of HLA-DRA 15.39 0.70 31 6
95 INT1002 Regulation of Localization of Ggh 0.63 0.58 10 5.98
96 INT52907 Regulation of Gene_expression of HLA-DRA 5.94 0.34 28 5.96
97 INT163540 Gene_expression of HYAL1 12.11 0.68 27 5.95
98 INT4888 Positive_regulation of Gene_expression of Ppt1 2.78 0.54 9 5.83
99 INT1242 Negative_regulation of Slc17a5 4.06 0.42 14 5.78
100 INT29674 Gene_expression of Ada 4.59 0.78 16 5.69
101 INT3731 Negative_regulation of Neu1 8.35 0.39 17 5.67
102 INT1243 Regulation of ADRB2 1.84 0.54 16 5.66
103 INT30206 Negative_regulation of ADA 10.03 0.59 17 5.63
104 INT102836 Binding of LRP2 11.27 0.38 12 5.58
105 INT118124 Binding of USE1 16.64 0.16 24 5.44
106 INT55353 Negative_regulation of Positive_regulation of Ppt1 0.31 0.57 9 5.37
107 INT38366 Regulation of Cat 23.45 0.62 45 5.34
108 INT23725 Gene_expression of CCKAR 0.14 0.55 14 5.3
109 INT12854 Negative_regulation of Gusb 3.25 0.42 11 5.28
110 INT3550 Negative_regulation of GLA 33.93 0.59 52 5.26
111 INT102547 Gene_expression of Cd68 14.47 0.75 25 5.22
112 INT24080 Negative_regulation of Mtor 41.56 0.37 64 5.19
113 INT68202 Gene_expression of ADA 23.15 0.68 26 5.18
114 INT65554 Positive_regulation of Hpse 8.16 0.69 13 5.17
115 INT36256 Regulation of Ada 4.99 0.62 9 5.07
116 INT9767 Negative_regulation of Ada 0.06 0.55 5 5.06
117 INT23611 Gene_expression of Mtor 3.57 0.66 23 5.02
118 INT7479 Positive_regulation of Ggh 5.71 0.62 13 5.02
119 INT3163 Gene_expression of NAGLU 15.23 0.75 28 4.98
120 INT1285 Localization of Mmp13 8.98 0.78 12 4.93
121 INT201653 Gene_expression of Sort1 6.29 0.75 6 4.89
122 INT3476 Phosphorylation of Npc1 0 0.48 7 4.84
123 INT7170 Positive_regulation of Positive_regulation of Ctsb 0 0.40 1 4.76
124 INT188672 Positive_regulation of Tlr9 13.1 0.67 15 4.48
125 INT36237 Gene_expression of Ass1 2.31 0.24 11 4.38
126 INT32569 Localization of GGH 2.46 0.80 18 4.3
127 INT87780 Gene_expression of Gja1 5.84 0.77 22 4.24
128 INT129964 Negative_regulation of MMP13 6.48 0.55 23 4.21
129 INT1701 Localization of Neu1 6.36 0.69 11 4.18
130 INT149986 Positive_regulation of Gene_expression of Tlr9 8.18 0.67 5 4.15
131 INT173910 Gene_expression of LRP2 19.99 0.75 24 4.09
132 INT253970 Positive_regulation of Cd74 8.16 0.48 3 4.09
133 INT47298 Localization of Ctsl 3.77 0.79 13 4.08
134 INT76227 Binding of NPC1 32.31 0.41 30 4.05
135 INT169555 Gene_expression of Acpp 5.55 0.68 8 4.01
136 INT183207 Negative_regulation of USE1 10.97 0.18 14 4
137 INT204529 Positive_regulation of TLR9 15.62 0.62 18 3.99
138 INT4530 Regulation of Ggh 2.5 0.54 9 3.96
139 INT134590 Localization of ADA 8.43 0.65 7 3.96
140 INT14619 Positive_regulation of Localization of NAGLU 7.73 0.62 18 3.94
141 INT15133 Regulation of HLA-DRA 5.84 0.34 19 3.9
142 INT119330 Binding of Calcrl 1.96 0.37 8 3.85
143 INT94406 Regulation of Slc17a5 3.71 0.44 10 3.77
144 INT102452 Gene_expression of RAMP2 7.11 0.69 6 3.77
145 INT149614 Localization of MMP13 6.12 0.81 13 3.65
146 INT2877 Localization of GUSB 0.81 0.80 9 3.63
147 INT32464 Regulation of Mmp13 6.46 0.44 12 3.61
148 INT129960 Negative_regulation of Gene_expression of MMP13 7.17 0.53 19 3.55
149 INT55352 Regulation of Gene_expression of Ppt1 0.4 0.44 9 3.51
150 INT61734 Regulation of HPSE 13.05 0.60 16 3.5
151 INT183371 Positive_regulation of Galc 7.27 0.67 11 3.49
152 INT57728 Regulation of LDLR 13.18 0.41 25 3.46
153 INT118270 Regulation of P2RY2 7.02 0.45 16 3.45
154 INT187168 Binding of Cd74 11.2 0.27 13 3.44
155 INT1970 Localization of Gusb 3.46 0.75 11 3.42
156 INT40844 Localization of Naga 2.88 0.53 2 3.42
157 INT116281 Negative_regulation of Gene_expression of Mmp13 9.96 0.41 15 3.41
158 INT126560 Binding of P2RY2 6.43 0.44 12 3.4
159 INT72798 Binding of ADA 7.84 0.47 12 3.39
160 INT13321 Negative_regulation of Hpse 4.64 0.56 11 3.39
161 INT28390 Negative_regulation of Mt1a 1.13 0.36 4 3.39
162 INT14994 Positive_regulation of Localization of MPO 6.85 0.70 12 3.37
163 INT148892 Binding of HPS1 19.21 0.37 13 3.35
164 INT111369 Transcription of Mt1a 1.01 0.68 4 3.35
165 INT87517 Gene_expression of LDLR 37.35 0.69 73 3.32
166 INT5166 Binding of Ldlr 11.95 0.48 14 3.32
167 INT102347 Localization of P2ry2 1.23 0.56 4 3.31
168 INT14857 Negative_regulation of Gene_expression of Ppt1 1.16 0.42 7 3.3
169 INT24983 Binding of MPO 17.56 0.42 18 3.29
170 INT3919 Localization of Got1 2.95 0.71 10 3.28
171 INT1972 Negative_regulation of Localization of Gusb 3.24 0.55 8 3.27
172 INT28249 Positive_regulation of HLA-DRA 13.63 0.70 25 3.25
173 INT102451 Localization of CALCRL 0 0.69 9 3.25
174 INT124606 Positive_regulation of Gene_expression of Mpo 12.66 0.49 14 3.24
175 INT188406 Binding of Fasl 24.67 0.44 19 3.17
176 INT19392 Gene_expression of Ada 7.4 0.77 9 3.17
177 INT131123 Gene_expression of Gba 3.74 0.78 22 3.14
178 INT12948 Positive_regulation of Gene_expression of Cat 6.46 0.67 17 3.12
179 INT34604 Binding of Ada 4.15 0.31 11 3.1
180 INT84320 Negative_regulation of Positive_regulation of Mpo 8 0.46 11 3.09
181 INT9766 Positive_regulation of Ada 0.4 0.47 2 3.09
182 INT137961 Localization of Ppt1 2.89 0.64 1 3.09
183 INT27446 Negative_regulation of CTSA 5.58 0.57 11 3.08
184 INT174117 Gene_expression of Cd1d1 12.07 0.75 26 3.07
185 INT4728 Negative_regulation of Positive_regulation of PPT1 0.29 0.42 2 3.07
186 INT7909 Positive_regulation of Positive_regulation of Got1 6.44 0.49 8 3.06
187 INT10057 Gene_expression of Ldlr 23.99 0.67 35 3.05
188 INT58302 Regulation of Mpo 11.14 0.62 13 3.04
189 INT41474 Gene_expression of ADRB2 1.56 0.75 10 2.94
190 INT108501 Binding of ARSD 11.5 0.32 14 2.93
191 INT153946 Localization of Slc17a5 4.83 0.66 8 2.93
192 INT90818 Gene_expression of Cckar 0 0.77 1 2.93
193 INT260424 Negative_regulation of Tlr9 8.19 0.41 8 2.92
194 INT79722 Regulation of Cat 5.88 0.62 14 2.86
195 INT85947 Regulation of Cckar 2.4 0.36 2 2.86
196 INT187073 Positive_regulation of Gene_expression of ARSD 4.49 0.28 1 2.85
197 INT45971 Negative_regulation of GOT1 6.2 0.51 9 2.84
198 INT78568 Negative_regulation of Gene_expression of Glb1 0.78 0.30 4 2.84
199 INT41721 Negative_regulation of MTOR 32.49 0.58 40 2.83
200 INT325976 Negative_regulation of Gene_expression of Ifi30 0.56 0.19 1 2.78
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