GOS:methyltransferase activity

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This page displays the top molecular interactions and top single events that were mentioned in the literature for methyltransferase activity. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for methyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported for methyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to methyltransferase activity Documents TM Confidence Disease Relevance Pain Relevance
1 INT91271 Mtr Regulation of Gene_expression of Il6 2 1 0.20 0 3.17
2 INT73116 TYMS Negative_regulation of DNMT3B 1 1 0.24 0 1.6
3 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 1 0.24 0 1.6
4 INT172203 Binding of Comt and Maoa 1 1 0.31 0.98 1.43
5 INT27425 Mtr Positive_regulation of Gene_expression of Il1f5 2 1 0.06 0 1.3
6 INT262377 Binding of Comt and Fmod 1 1 0.06 1.47 1.29
7 INT45891 Tyms Positive_regulation of Localization of Acot1 1 1 0.02 0 1.23
8 INT107561 Mtr Positive_regulation of Localization of Il1b 2 1 0.04 0.09 1.09
9 INT107563 Penk Regulation of Mtr 2 1 0.00 0.1 1.04
10 INT107565 Hps4 Regulation of Mtr 2 1 0.00 0.1 1.04
11 INT72213 Positive_regulation of PRKCA Regulation of Gene_expression of METTL3 1 1 0.05 0.17 0.93
12 INT91273 Mtr Positive_regulation of Localization of Il6 2 1 0.17 0 0.88
13 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 1 0.32 1.26 0.84
14 INT340115 Comt Regulation of Localization of Dusp1 1 1 0.12 0.83 0.83
15 INT340114 Comt Regulation of Localization of Pain1 1 1 0.02 0.83 0.83
16 INT340113 Comt Regulation of Bdnf 1 1 0.21 0.74 0.82
17 INT54669 Mtr Regulation of Gene_expression of Il1 2 1 0.02 0.2 0.77
18 INT54668 Mtr Regulation of Gene_expression of Il1f5 2 1 0.00 0.2 0.76
19 INT327707 Binding of Comt and Drd1a 1 1 0.18 0.27 0.74
20 INT327702 Binding of Comt and Drd2 1 1 0.28 0.27 0.74
21 INT327712 Binding of Comt and Rbm39 1 1 0.00 0.27 0.74
22 INT46657 Mtr Regulation of Gnrh1 2 1 0.01 0 0.71
23 INT46656 Mtr Regulation of Prl 2 1 0.05 0 0.7
24 INT38820 Binding of MTR and PDYN 1 1 0.03 0.19 0.65
25 INT27426 Mtr Positive_regulation of Localization of Il1f5 2 1 0.06 0 0.63
26 INT50935 Mtr Regulation of Gene_expression of Il6 2 1 0.00 0 0.53
27 INT168256 Binding of MLL and TNFRSF1B 1 1 0.00 1.2 0.53
28 INT321598 Binding of MLL and TNF 1 1 0.05 1.07 0.49
29 INT101327 Binding of Cnr1 and Amt 1 1 0.25 0 0.47
30 INT28863 Mtr Negative_regulation of Dhfr 2 1 0.04 0.87 0.45
31 INT189681 Negative_regulation of PRKCA Negative_regulation of Gene_expression of METTL3 1 1 0.00 0.16 0.41
32 INT13715 PDYN Positive_regulation of TYMS 1 1 0.27 0 0.39
33 INT151694 Binding of FBL and RNF130 1 1 0.40 0.23 0.36
34 INT330464 Setd1a Regulation of Gene_expression of RT1-CE1 1 1 0.00 0.47 0.35
35 INT327701 Comt Regulation of Npcd 1 1 0.01 0 0.29
36 INT327706 Comt Regulation of Gopc 1 1 0.10 0 0.29
37 INT51088 Binding of CDS1 and PRMT1 1 1 0.06 0 0.28
38 INT105003 Binding of PDYN and SHMT2 1 1 0.04 0.49 0.26
39 INT216040 Binding of Comt and Prodh 1 1 0.30 1.71 0.26
40 INT101326 Negative_regulation of Binding of Cnr1 and Amt 1 1 0.29 0 0.25
41 INT330463 Setd1a Positive_regulation of Regulation of Adh1 1 1 0.00 0.09 0.23
42 INT50934 Mtr Positive_regulation of Gene_expression of Il6 2 1 0.00 0 0.2
43 INT327700 Binding of Comt and 4930579C15Rik 1 1 0.08 0 0.15
44 INT73923 FBL Positive_regulation of Localization of COL7A1 1 1 0.36 0.33 0.13
45 INT327703 Cish Regulation of Transcription of Comt 1 1 0.13 0.77 0.12
46 INT84867 Ptger1 Negative_regulation of SETD2 1 1 0.00 1.09 0.11
47 INT83827 Negative_regulation of Binding of Adrb1 and Pnmt 1 1 0.02 0 0.1
48 INT83831 Binding of PNMT and Adrb1 1 1 0.02 0 0.1
49 INT83828 Binding of Adrb1 and Pnmt 1 1 0.01 0 0.1
50 INT232653 Binding of CD2 and MLL 1 1 0.02 0.27 0.1
51 INT83832 Negative_regulation of Binding of PNMT and Adrb1 1 1 0.02 0 0.1
52 INT215461 Binding of MLL and TNFSF13B 1 1 0.01 1.62 0.1
53 INT327709 Uts2r Positive_regulation of Comt 1 1 0.14 0.47 0.1
54 INT299955 Binding of KDR and FTSJ3 1 1 0.04 1.07 0.09
55 INT165619 Binding of LPL and TGS1 1 1 0.04 0.61 0.09
56 INT48194 Pdgfb Positive_regulation of Setd1a 1 1 0.23 0 0.09
57 INT299953 Binding of CD34 and FTSJ3 1 1 0.04 1.07 0.09
58 INT330855 Binding of Ins1 and Tgs1 1 1 0.02 0.86 0.09
59 INT66171 Negative_regulation of Adra2a Negative_regulation of Positive_regulation of Pnmt 1 1 0.38 0 0.08
60 INT130958 Binding of Eif4h and Ash1l 1 1 0.07 0.29 0.08
61 INT66166 Negative_regulation of Binding of Pnmt and Adra2a 1 1 0.38 0 0.07
62 INT245985 Binding of MTR and Mtrr 1 1 0.06 0.8 0.07
63 INT66167 Negative_regulation of Pnmt Negative_regulation of Adra2a 1 1 0.38 0 0.07
64 INT66172 Binding of Pnmt and Adra2a 1 1 0.33 0 0.07
65 INT156144 MLL Positive_regulation of Epcam 1 1 0.00 0.47 0.06
66 INT312940 Chol1 Positive_regulation of Setd1a 1 1 0.00 0 0.06
67 INT156143 MLL Positive_regulation of PECAM1 1 1 0.00 0.47 0.06
68 INT321399 Positive_regulation of SETD7 Positive_regulation of SETDB1 2 1 0.00 1.25 0.06
69 INT245986 MTR Regulation of Mthfr 1 1 0.07 0.18 0.05
70 INT267158 Binding of IRS1 and SHMT2 1 1 0.02 0.46 0.05
71 INT245966 TCN1 Regulation of MTR 1 1 0.02 0.18 0.05
72 INT299954 Negative_regulation of LXN Negative_regulation of FTSJ3 1 1 0.00 0.75 0.05
73 INT245967 Negative_regulation of TCN1 Regulation of MTR 1 1 0.02 0.18 0.05
74 INT290727 Binding of Prdm6 and Arsi 1 1 0.01 0.17 0.04
75 INT245987 Binding of MTR and Mthfr 1 1 0.11 0.48 0.03
76 INT332938 Suv39h1 Positive_regulation of Hist1h3f 1 1 0.06 0.12 0.03
77 INT332937 Hnmt Positive_regulation of Hist1h3f 1 1 0.01 0.12 0.03
78 INT241459 Gart Positive_regulation of Racgap1 1 1 0.01 0 0.03
79 INT321398 SETD7 Positive_regulation of SETDB1 2 1 0.00 0.62 0.03
80 INT183412 Dnmt3a Positive_regulation of Tbx15 1 1 0.05 0.27 0
81 INT301474 Binding of Helz and Smyd2 1 1 0.40 0.14 0
82 INT348584 EZH2 Regulation of Gene_expression of PPARG 1 1 0.30 0.43 0
83 INT279905 Binding of SNRNP70 and TGS1 1 1 0.01 1.85 0
84 INT250953 Binding of USO1 and SETDB1 1 1 0.00 0.09 0
85 INT279900 Binding of RS1 and TGS1 1 1 0.00 1.12 0
86 INT225550 Binding of Mybbp1a and Carm1 1 1 0.06 0 0
87 INT339096 Ezh2 Regulation of Rcc1 1 1 0.02 1.1 0
88 INT348588 MECP2 Positive_regulation of Gene_expression of EZH2 1 1 0.28 0.42 0
89 INT301464 Binding of Smyd3 and Dhx8 1 1 0.05 0.08 0
90 INT348596 EZH2 Positive_regulation of Gene_expression of MECP2 1 1 0.28 0.42 0
91 INT279894 Binding of USF1 and TGS1 1 1 0.11 3.52 0
92 INT183413 Dnmt3a Positive_regulation of Gene_expression of Dnmt3b 2 1 0.10 0.28 0
93 INT301473 Binding of Dhx8 and Smyd2 1 1 0.06 0.14 0
94 INT225521 Binding of Prmt1 and Mybbp1a 1 1 0.05 0 0
95 INT229884 Gart Regulation of AKT1 1 1 0.02 0.4 0
96 INT183415 Dnmt3b Positive_regulation of Gene_expression of Dnmt3a 2 1 0.10 0.28 0
97 INT301466 Smyd2 Negative_regulation of Binding of Trp53 and 1 1 0.20 0.3 0
98 INT348591 EZH2 Regulation of Negative_regulation of MECP2 1 1 0.15 0.73 0
99 INT301468 Smyd2 Negative_regulation of Trp53 1 1 0.20 0.31 0
100 INT301467 Binding of Smyd3 and Helz 1 1 0.30 0.08 0
101 INT301469 Negative_regulation of Binding of Sin3a and Smyd2 1 1 0.28 0.31 0
102 INT301478 Smyd2 Negative_regulation of Binding of Smyd2 and Hdac1 1 1 0.36 0.31 0
103 INT312939 Binding of Hes3 and Setd1a 1 1 0.01 0.66 0
104 INT301477 Smyd2 Negative_regulation of Binding of Sin3a and Smyd2 1 1 0.33 0.31 0
105 INT183410 Dnmt3b Positive_regulation of Tbx15 1 1 0.05 0.27 0
106 INT279909 Binding of FADS3 and TGS1 1 1 0.12 6 0
107 INT301475 Binding of Sin3a and Smyd2 1 1 0.32 0.31 0
108 INT250955 Binding of HLA-B and SETDB1 1 1 0.01 0.08 0
109 INT312945 ANTXR1 Regulation of Setd1a 1 1 0.00 0.36 0
110 INT335607 Binding of INS and TGS1 1 1 0.04 0.95 0
111 INT225537 Binding of Paxip1 and Mll2 1 1 0.12 0 0
112 INT301472 Binding of Polr2a and Smyd3 1 1 0.06 0.08 0
113 INT301470 Binding of Smyd2 and Hdac1 1 1 0.35 0.31 0
114 INT348585 EZH2 Regulation of PPARG 1 1 0.41 0.73 0
115 INT297846 Nanos2 Regulation of Dnmt3l 1 1 0.34 0.6 0
116 INT191135 Binding of DNMT3A and DNMT3B 1 1 0.09 0 0
117 INT279910 SNRNP70 Regulation of TGS1 1 1 0.01 0.76 0
118 INT301463 Negative_regulation of Smyd2 Positive_regulation of Gene_expression of Smyd1 1 1 0.54 0.1 0
119 INT147144 E2F1 Positive_regulation of Transcription of TYMS 1 1 0.26 0 0
120 INT227843 Binding of ERCC6 and MLL 1 1 0.00 0.34 0
121 INT342096 Binding of Polr2f and Ehmt1 1 1 0.00 0.73 0
122 INT225544 Binding of Prmt1 and Pprc1 1 1 0.00 0 0
123 INT342439 PPP2CA Negative_regulation of PRMT1 1 1 0.12 0.63 0
124 INT254850 Setd1a Negative_regulation of Rac1 1 1 0.00 0 0
125 INT194925 Binding of CD22 and MLL2 1 1 0.08 0.18 0
126 INT301471 Binding of Smyd1 and Smyd2 1 1 0.40 0.2 0
127 INT234144 Fig4 Negative_regulation of Transcription of Tyms 1 1 0.05 0.18 0
128 INT301476 Binding of Polr2a and Smyd2 1 1 0.08 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for methyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported in methyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13
2 INT3362 Negative_regulation of Emg1 21 0.57 10.03 15.93
3 INT1672 Gene_expression of Mtr 18 0.67 3.39 13.32
4 INT101119 Negative_regulation of Comt 19 0.58 8.77 13.09
5 INT18539 Gene_expression of Pnmt 33 0.78 3.08 12.47
6 INT3922 Negative_regulation of Pnmt 29 0.59 3.18 8.96
7 INT44537 Positive_regulation of Comt 7 0.69 2.62 7.78
8 INT72219 Gene_expression of METTL3 45 0.24 9.58 7.61
9 INT9802 Positive_regulation of Mtr 9 0.60 3.69 7.43
10 INT101121 Regulation of Comt 19 0.53 10.66 7.22
11 INT35811 Positive_regulation of Emg1 10 0.41 4.41 6.92
12 INT23132 Positive_regulation of Pnmt 17 0.67 2.02 6.84
13 INT46518 Localization of Mtr 12 0.65 1.31 6.55
14 INT150825 Binding of Comt 13 0.42 6.65 6.42
15 INT32778 Gene_expression of Mettl15 6 0.70 0.98 5.86
16 INT10006 Regulation of Mtr 9 0.23 3.56 5.42
17 INT12250 Negative_regulation of Mtr 19 0.50 6.9 5.35
18 INT14455 Transcription of Pnmt 17 0.72 2.13 4.95
19 INT12380 Localization of Pnmt 10 0.80 0.07 4.7
20 INT9803 Positive_regulation of Gene_expression of Mtr 3 0.60 1.45 4.36
21 INT172197 Positive_regulation of Gene_expression of Comt 12 0.69 7.61 4.06
22 INT18538 Regulation of Pnmt 11 0.60 1.03 3.84
23 INT27595 Negative_regulation of EMG1 14 0.38 4.26 3.61
24 INT14319 Localization of SHMT2 3 0.03 1.91 3.61
25 INT172198 Protein_catabolism of Comt 7 0.88 2.78 3.6
26 INT206598 Regulation of Gene_expression of Comt 9 0.60 6 3.56
27 INT195964 Transcription of Comt 8 0.71 4.72 3.4
28 INT24751 Gene_expression of Mtr 8 0.36 1.34 3.34
29 INT42578 Regulation of Mettl15 1 0.49 0.34 3.29
30 INT19145 Negative_regulation of Edf1 7 0.00 0.29 3.25
31 INT66347 Gene_expression of MLL 29 0.65 14.82 3.18
32 INT3869 Gene_expression of SHMT2 7 0.37 3.6 3.03
33 INT271463 Gene_expression of Rg9mtd2 6 0.06 22.25 2.99
34 INT52911 Gene_expression of Tyms 10 0.42 2.24 2.66
35 INT3123 Localization of Tyms 6 0.78 0.85 2.6
36 INT206593 Negative_regulation of Gene_expression of Comt 3 0.56 1.68 2.52
37 INT213681 Gene_expression of TYMS 9 0.33 8.96 2.45
38 INT68443 Positive_regulation of METTL3 9 0.12 3.54 2.39
39 INT28468 Positive_regulation of Transcription of Pnmt 4 0.67 0.63 2.04
40 INT68638 Negative_regulation of Hnmt 1 0.58 0.63 2.04
41 INT260964 Positive_regulation of Rg9mtd2 7 0.07 5.08 1.95
42 INT74122 Gene_expression of Emg1 2 0.47 0.51 1.89
43 INT131817 Negative_regulation of Asmt 1 0.02 1.59 1.85
44 INT213676 Negative_regulation of Gene_expression of TYMS 2 0.08 1.95 1.83
45 INT174240 Negative_regulation of TYMS 12 0.57 6.35 1.82
46 INT25582 Regulation of Mtr 2 0.03 0.4 1.76
47 INT73927 Gene_expression of FBL 10 0.48 3.55 1.72
48 INT77818 Positive_regulation of EMG1 24 0.54 2.73 1.59
49 INT180185 Gene_expression of MGMT 22 0.65 15.02 1.57
50 INT144537 Negative_regulation of TPMT 1 0.59 0.63 1.57
51 INT44493 Regulation of SHMT2 3 0.29 0.45 1.55
52 INT32779 Positive_regulation of Gene_expression of Mettl15 1 0.63 0.3 1.55
53 INT67447 Binding of Aldh1l1 1 0.42 0.7 1.48
54 INT47446 Regulation of Localization of Mtr 1 0.05 0.07 1.42
55 INT28478 Regulation of Gene_expression of Pnmt 5 0.44 0 1.41
56 INT52994 Positive_regulation of Positive_regulation of Emg1 1 0.41 0.86 1.41
57 INT79361 Negative_regulation of Prdm6 5 0.51 3.79 1.4
58 INT299978 Regulation of FTSJ3 1 0.07 8.47 1.36
59 INT19619 Positive_regulation of SHMT2 6 0.08 1.05 1.35
60 INT9217 Negative_regulation of MTR 17 0.58 1.13 1.32
61 INT48192 Gene_expression of Setd1a 8 0.42 4.41 1.26
62 INT2595 Binding of Mtr 1 0.29 0 1.24
63 INT52912 Binding of Tyms 5 0.46 0.78 1.16
64 INT22480 Binding of SHMT2 5 0.19 2.31 1.14
65 INT72218 Regulation of METTL3 5 0.08 1.62 1.14
66 INT101323 Negative_regulation of Amt 1 0.40 0 1.14
67 INT28469 Positive_regulation of Gene_expression of Pnmt 4 0.49 0.73 1.11
68 INT23717 Localization of PNMT 1 0.28 0.06 1.1
69 INT177910 Gene_expression of AS3MT 7 0.23 6.94 1.08
70 INT81418 Positive_regulation of Localization of SHMT2 1 0.02 0.75 1.06
71 INT47131 Negative_regulation of Localization of Mtr 1 0.41 0 1.06
72 INT157361 Localization of MTR 2 0.31 1.4 1.05
73 INT72215 Regulation of Gene_expression of METTL3 2 0.08 0.25 1.04
74 INT24750 Negative_regulation of Mtr 1 0.22 0.06 1.04
75 INT66430 Localization of Trmt12 1 0.11 0 1.01
76 INT103240 Negative_regulation of Tyms 4 0.57 1.7 0.99
77 INT51089 Negative_regulation of PRMT1 3 0.24 1.18 0.98
78 INT299964 Positive_regulation of FTSJ3 1 0.08 7.32 0.98
79 INT299967 Negative_regulation of FTSJ3 1 0.07 11.72 0.97
80 INT52995 Regulation of Positive_regulation of Emg1 1 0.24 0.75 0.93
81 INT170813 Gene_expression of Prdm6 11 0.65 4.35 0.88
82 INT72220 Negative_regulation of METTL3 6 0.10 1.76 0.88
83 INT31014 Negative_regulation of Setd1a 4 0.27 1.11 0.88
84 INT282479 Regulation of Protein_catabolism of Comt 2 0.45 1.17 0.85
85 INT67446 Negative_regulation of Aldh1l1 1 0.59 0.27 0.82
86 INT47518 Negative_regulation of Positive_regulation of Pnmt 2 0.42 0.32 0.8
87 INT153120 Gene_expression of Gnmt 2 0.02 0.17 0.78
88 INT32777 Regulation of Gene_expression of Mettl15 1 0.56 0.2 0.78
89 INT195983 Localization of Comt 2 0.74 0.93 0.76
90 INT299981 Gene_expression of FTSJ3 6 0.09 3.08 0.74
91 INT165621 Negative_regulation of TGS1 4 0.14 4.5 0.72
92 INT108170 Gene_expression of Tyms 6 0.69 1.97 0.71
93 INT271460 Regulation of Rg9mtd2 1 0.05 3.57 0.71
94 INT90496 Gene_expression of Dnmt1 9 0.60 5.44 0.7
95 INT24584 Positive_regulation of MTR 4 0.44 0.07 0.7
96 INT41532 Gene_expression of PNMT 2 0.61 0.89 0.69
97 INT12379 Regulation of Localization of Pnmt 1 0.17 0 0.69
98 INT68639 Regulation of Hnmt 1 0.45 0.15 0.68
99 INT151745 Negative_regulation of Gene_expression of METTL3 2 0.11 0.58 0.64
100 INT146710 Negative_regulation of Mepce 1 0.01 0.68 0.63
101 INT307096 Regulation of Prmt1 1 0.01 0.92 0.63
102 INT307095 Negative_regulation of Regulation of Prmt1 1 0.02 0.93 0.63
103 INT10007 Regulation of Gene_expression of Mtr 2 0.23 1.17 0.61
104 INT41533 Regulation of PNMT 1 0.44 0.07 0.61
105 INT14109 Positive_regulation of Mtr 1 0.03 0.49 0.6
106 INT299980 Positive_regulation of Gene_expression of FTSJ3 1 0.08 1.48 0.6
107 INT60829 Negative_regulation of Negative_regulation of Emg1 1 0.38 0.78 0.6
108 INT151697 Binding of FBL 2 0.36 2.06 0.59
109 INT139312 Negative_regulation of Gene_expression of MLL 2 0.00 1.22 0.56
110 INT252576 Binding of Emg1 1 0.32 0.77 0.56
111 INT168257 Binding of MLL 4 0.02 4.25 0.53
112 INT13717 Positive_regulation of TYMS 3 0.40 1.64 0.49
113 INT117358 Positive_regulation of Pnmt 1 0.40 0.1 0.49
114 INT14458 Transcription of PNMT 1 0.69 0.09 0.49
115 INT14459 Positive_regulation of Transcription of PNMT 1 0.45 0.09 0.49
116 INT327677 Regulation of Transcription of Comt 2 0.60 1.49 0.48
117 INT46821 Positive_regulation of Negative_regulation of EMG1 2 0.36 0.67 0.48
118 INT78201 Regulation of MLL 2 0.02 0.79 0.48
119 INT106120 Transcription of Pnmt 1 0.52 0.28 0.48
120 INT187557 Localization of METTL3 1 0.01 2.3 0.47
121 INT213434 Gene_expression of HNMT 4 0.64 4.33 0.46
122 INT117357 Negative_regulation of Pnmt 1 0.37 0.09 0.46
123 INT144002 Positive_regulation of Gene_expression of METTL3 2 0.02 0.16 0.44
124 INT66991 Positive_regulation of Prdm6 2 0.16 0.86 0.44
125 INT107502 Negative_regulation of Gamt 3 0.59 1.18 0.43
126 INT250961 Gene_expression of SETDB1 1 0.03 0.75 0.43
127 INT24583 Protein_catabolism of MTR 1 0.57 0 0.42
128 INT232362 Gene_expression of Mgmt 10 0.76 8.08 0.41
129 INT156944 Positive_regulation of Setd1a 2 0.30 1.31 0.41
130 INT51090 Gene_expression of PRMT1 1 0.59 0.27 0.41
131 INT65944 Positive_regulation of Dnmt1 2 0.33 0.76 0.39
132 INT48359 Positive_regulation of Positive_regulation of Nsd1 1 0.41 0 0.39
133 INT306690 Negative_regulation of Dnmt3b 1 0.00 0.56 0.39
134 INT180184 Positive_regulation of Gene_expression of MGMT 5 0.48 4.75 0.38
135 INT48360 Positive_regulation of Nsd1 1 0.41 0 0.38
136 INT54952 Binding of Mtr 1 0.03 0.58 0.37
137 INT238902 Binding of TGS1 3 0.07 2.86 0.36
138 INT151695 Positive_regulation of FBL 2 0.49 0.65 0.36
139 INT189726 Positive_regulation of Positive_regulation of METTL3 1 0.01 0.16 0.36
140 INT113283 Negative_regulation of Tyms 2 0.41 0.4 0.35
141 INT160666 Binding of Prdm6 2 0.31 0.73 0.35
142 INT350211 Gene_expression of Tfb2m 1 0.08 0.71 0.35
143 INT101539 Regulation of EMG1 23 0.48 0.99 0.33
144 INT26194 Regulation of MTR 1 0.19 1.1 0.33
145 INT166893 Negative_regulation of Gene_expression of Mtr 1 0.03 0.57 0.33
146 INT37319 Localization of Pnmt 1 0.78 0.34 0.33
147 INT156943 Negative_regulation of Negative_regulation of Setd1a 1 0.18 0.71 0.32
148 INT106025 Binding of TPMT 1 0.37 0.74 0.32
149 INT73925 Regulation of FBL 3 0.22 2.19 0.31
150 INT221798 Negative_regulation of Whsc1 1 0.01 0.31 0.31
151 INT297458 Positive_regulation of Trmt12 1 0.01 0.9 0.31
152 INT65943 Binding of Dnmt1 1 0.16 0.43 0.3
153 INT65945 Positive_regulation of Binding of Dnmt1 1 0.21 0.43 0.3
154 INT135759 Positive_regulation of Setmar 1 0.05 0.48 0.3
155 INT68442 Transcription of METTL3 2 0.03 0.98 0.29
156 INT232656 Localization of MLL 2 0.05 2.33 0.29
157 INT232363 Positive_regulation of Gene_expression of Mgmt 8 0.49 6.01 0.28
158 INT156942 Positive_regulation of Gene_expression of Setd1a 1 0.21 0.58 0.28
159 INT299983 Localization of FTSJ3 1 0.09 3.24 0.28
160 INT271465 Regulation of Localization of Rg9mtd2 1 0.04 1.24 0.28
161 INT271468 Localization of Rg9mtd2 1 0.07 1.23 0.28
162 INT83525 Negative_regulation of Transcription of Pnmt 3 0.57 0 0.27
163 INT282213 Negative_regulation of Regulation of Mtr 1 0.01 0.82 0.27
164 INT81122 Positive_regulation of Edf1 4 0.41 0 0.26
165 INT285145 Positive_regulation of MGMT 3 0.48 4.09 0.26
166 INT83829 Negative_regulation of PNMT 3 0.57 0 0.26
167 INT344908 Negative_regulation of Bhmt 1 0.57 0.5 0.26
168 INT102828 Protein_catabolism of SHMT2 1 0.02 0 0.26
169 INT344907 Negative_regulation of Negative_regulation of Bhmt 1 0.41 0.5 0.26
170 INT344904 Regulation of Gnmt 1 0.60 0.26 0.25
171 INT83526 Negative_regulation of Gene_expression of Pnmt 1 0.41 0 0.25
172 INT191147 Negative_regulation of Gene_expression of Dnmt1 3 0.45 3.03 0.24
173 INT7259 Negative_regulation of Nsd1 1 0.18 0.06 0.24
174 INT300944 Regulation of DNMT3A 1 0.21 0.91 0.24
175 INT323229 Positive_regulation of Tgs1 2 0.17 4.63 0.23
176 INT237464 Positive_regulation of Negative_regulation of TYMS 2 0.20 0.53 0.23
177 INT310319 Gene_expression of Coq3 1 0.65 0.51 0.23
178 INT275355 Negative_regulation of Gene_expression of Rg9mtd2 1 0.04 0.33 0.23
179 INT81123 Regulation of Edf1 3 0.37 0 0.21
180 INT233294 Positive_regulation of Mgmt 2 0.49 4.07 0.21
181 INT126854 Regulation of Emg1 2 0.24 0.67 0.21
182 INT70913 Gene_expression of MTR 2 0.12 0.44 0.21
183 INT107342 Binding of INMT 1 0.06 0.93 0.21
184 INT187554 Positive_regulation of Transcription of METTL3 1 0.01 0.98 0.21
185 INT299968 Regulation of Negative_regulation of FTSJ3 1 0.05 1.24 0.2
186 INT327698 Regulation of Binding of Comt 1 0.39 0 0.2
187 INT183714 Gene_expression of EMG1 17 0.60 1.59 0.19
188 INT227872 Positive_regulation of MLL 7 0.01 2.44 0.19
189 INT183713 Localization of EMG1 5 0.58 0.37 0.19
190 INT233296 Negative_regulation of Mgmt 3 0.57 1.9 0.19
191 INT261365 Binding of Tgs1 2 0.04 1.96 0.19
192 INT183712 Binding of EMG1 2 0.29 0.27 0.19
193 INT163512 Positive_regulation of TRMT12 1 0.58 0.38 0.19
194 INT16756 Regulation of Transcription of Pnmt 2 0.39 0.08 0.18
195 INT327691 Negative_regulation of Transcription of Comt 1 0.37 0.33 0.18
196 INT299970 Negative_regulation of Negative_regulation of FTSJ3 1 0.05 0.85 0.18
197 INT48193 Regulation of Setd1a 3 0.15 0.92 0.17
198 INT273293 Gene_expression of Hnmt 1 0.46 0.34 0.17
199 INT301442 Gene_expression of Smyd2 1 0.77 2.97 0.17
200 INT258302 Positive_regulation of PNMT 1 0.04 0.81 0.17
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