INT100325

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Context Info
Confidence 0.69
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (AQP2) plasma membrane (AQP2) protein complex (AQP2)
transmembrane transport (AQP2) lysosome (AQP2) cytoplasm (AQP2)
Anatomy Link Frequency
nephron 1
urine 1
AQP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 4 45.72 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 45.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We suggest that the increased excretion of AQP2 can be explained by an increase in the ratio of AQP2 that is shed into the urine because the endocytic retrieval of AQP2 from the apical membrane is impaired.
Positive_regulation (increase) of AQP2 in urine
1) Confidence 0.69 Published 2001 Journal Scand. J. Clin. Lab. Invest. Section Abstract Doc Link 11768323 Disease Relevance 0 Pain Relevance 0
Inhibition of renal prostaglandin synthesis by ibuprofen affects the distal part of the nephron by increasing u-AQP2.
Positive_regulation (increasing) of AQP2 in nephron
2) Confidence 0.60 Published 2001 Journal Scand. J. Clin. Lab. Invest. Section Abstract Doc Link 11768323 Disease Relevance 0 Pain Relevance 0

General Comments

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