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Context Info
Confidence 0.35
First Reported 1992
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 3.10
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ANXA3) cytoplasm (ANXA3)
Anatomy Link Frequency
plasma 1
ANXA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 6 96.84 Very High Very High Very High
Chronic low back pain 1 90.84 High High
metalloproteinase 5 89.12 High High
cytokine 1 54.72 Quite High
antagonist 1 31.44 Quite Low
depression 8 5.00 Very Low Very Low Very Low
palliative 4 5.00 Very Low Very Low Very Low
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
tricyclic antidepressant 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 15 99.40 Very High Very High Very High
Cv General 3 Under Development 6 96.84 Very High Very High Very High
Myocardial Infarction 4 95.48 Very High Very High Very High
Cancer 108 93.56 High High
Low Back Pain 1 90.84 High High
Disease 63 89.28 High High
Breast Cancer 10 85.88 High High
Thrombosis 1 83.36 Quite High
Bladder Cancer 7 77.00 Quite High
Affective Disorder 12 75.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Six proteins (ANXA3, BMP4, LCN2, SPARC, MMP7, and MMP11) were found to be over-expressed in colorectal tumoral tissues by using immunoblotting and tissue microarray analysis.
Gene_expression (expressed) of ANXA3
1) Confidence 0.35 Published 2007 Journal Mol Cancer Section Body Doc Link PMC1852117 Disease Relevance 0.95 Pain Relevance 0
The rise of DSM-III
Gene_expression (rise) of DSM-III
2) Confidence 0.11 Published 2009 Journal Philos Ethics Humanit Med Section Body Doc Link PMC2724409 Disease Relevance 0.59 Pain Relevance 0
Gerald Klerman, who coined the term 'neo-Kraepelinian' [6], outlined the benefits of DSM-III as follows:
Gene_expression (benefits) of DSM-III
3) Confidence 0.11 Published 2009 Journal Philos Ethics Humanit Med Section Body Doc Link PMC2724409 Disease Relevance 0.52 Pain Relevance 0
In degeneration, synthesis of matrix molecules changes, leading to an increase in the synthesis of collagens type I and III and a decreased production of aggrecan.
Gene_expression (synthesis) of and III
4) Confidence 0.10 Published 2007 Journal Biochem. Soc. Trans. Section Abstract Doc Link 17635113 Disease Relevance 0.27 Pain Relevance 0.19
Plasma antigen concentrations and/or activities of high-molecular-weight kininogen (HMWK), fibrinogen, fibronectin, plasminogen, D-dimer, tissue plasminogen activator (t-PA), alpha 2-antiplasmin, alpha 2-macroglobulin, alpha 1-antitrypsin, protein C, total and free protein S, antithrombin III (AT-III), von Willebrand factor (vWF), factors (F) XII, XI, IX, VIII, VII, X, V, II, and XIII, and plasma antiplasmin activity were measured using appropriate functional or immunologic assays.
Gene_expression (concentrations) of AT-III in plasma
5) Confidence 0.01 Published 1992 Journal Am. J. Med. Section Abstract Doc Link 1466361 Disease Relevance 0.77 Pain Relevance 0.35

General Comments

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