INT102007

From wiki-pain
Revision as of 12:32, 14 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 2002
Last Reported 2006
Negated 1
Speculated 0
Reported most in Abstract
Documents 7
Total Number 8
Disease Relevance 6.03
Pain Relevance 6.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Calca) aging (Calca) extracellular region (Calca)
nucleus (Calca) intracellular (Calca) cytoplasm (Calca)
Anatomy Mention Frequency
sciatic nerve 2
neurons 2
dorsal horn 2
bladder 1
DRG 1
Calca (Rattus norvegicus)
Pain Term Frequency Confidence Heat
Calcitonin gene-related peptide 45 100.00 Very High Very High Very High
Inflammation 18 100.00 Very High Very High Very High
substance P 8 99.90 Very High Very High Very High
Dorsal horn 6 98.92 Very High Very High Very High
Spinal cord 8 98.40 Very High Very High Very High
Sciatic nerve 6 97.24 Very High Very High Very High
dorsal root ganglion 12 97.08 Very High Very High Very High
unmyelinated 3 94.48 High High
allodynia 4 94.24 High High
peripheral neuropathy 2 93.48 High High
Disease Term Frequency Confidence Heat
INFLAMMATION 14 100.00 Very High Very High Very High
Hypersensitivity 2 98.64 Very High Very High Very High
Nervous System Injury 10 97.38 Very High Very High Very High
Ganglion Cysts 12 97.08 Very High Very High Very High
Neuropathic Pain 10 94.24 High High
Nociception 9 93.96 High High
Peripheral Neuropathy 2 93.48 High High
Increased Venous Pressure Under Development 9 92.64 High High
Injury 6 92.28 High High
Shock 4 91.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunocytochemical detection of calcitonin gene-related peptide (CGRP) and isolectin B4 (IB4) binding was used to visualize the dorsal horn distribution of the boutons from the peptidergic and non-peptidergic fibers respectively.
isolectin B4 Binding (binding) of CGRP in dorsal horn associated with dorsal horn and calcitonin gene-related peptide
1) Confidence 0.50 Published 2006 Journal Neuroscience Section Abstract Doc Link 16413131 Disease Relevance 0.90 Pain Relevance 0.80
Immunocytochemical detection of calcitonin gene-related peptide (CGRP) and isolectin B4 (IB4) binding was used to visualize the dorsal horn distribution of the boutons from the peptidergic and non-peptidergic fibers respectively.
isolectin B4 Binding (binding) of calcitonin gene-related peptide in dorsal horn associated with dorsal horn and calcitonin gene-related peptide
2) Confidence 0.39 Published 2006 Journal Neuroscience Section Abstract Doc Link 16413131 Disease Relevance 0.91 Pain Relevance 0.80
Following sciatic nerve injury in adult rats and treatment with BRX-220, the following features of the sensory system were studied: (a) expression of calcitonin gene-related peptide (CGRP); (b) binding of isolectin B4 (IB4) in dorsal root ganglia (DRG) and spinal cord; (c) stimulation-evoked release of substance P (SP) in an in vitro spinal cord preparation and (d) nociceptive responses of partially denervated rats.
isolectin B4 Binding (binding) of CGRP in sciatic nerve associated with nociception, nervous system injury, sciatic nerve, substance p, spinal cord and calcitonin gene-related peptide
3) Confidence 0.38 Published 2003 Journal Exp. Neurol. Section Abstract Doc Link 14769355 Disease Relevance 0.62 Pain Relevance 0.46
Following sciatic nerve injury in adult rats and treatment with BRX-220, the following features of the sensory system were studied: (a) expression of calcitonin gene-related peptide (CGRP); (b) binding of isolectin B4 (IB4) in dorsal root ganglia (DRG) and spinal cord; (c) stimulation-evoked release of substance P (SP) in an in vitro spinal cord preparation and (d) nociceptive responses of partially denervated rats.
isolectin B4 Binding (binding) of gene-related peptide in sciatic nerve associated with nociception, nervous system injury, sciatic nerve, substance p, spinal cord and calcitonin gene-related peptide
4) Confidence 0.33 Published 2003 Journal Exp. Neurol. Section Abstract Doc Link 14769355 Disease Relevance 0.62 Pain Relevance 0.46
One-third of CGRP-IR neurons that appear after inflammation also had isolectin B4 binding, suggesting that some mechanoreceptors became CGRP-IR.
isolectin B4 Binding (binding) of CGRP-IR in neurons associated with inflammation and calcitonin gene-related peptide
5) Confidence 0.29 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 16207882 Disease Relevance 1.41 Pain Relevance 1.51
One-third of CGRP-IR neurons that appear after inflammation also had isolectin B4 binding, suggesting that some mechanoreceptors became CGRP-IR.
isolectin B4 Binding (binding) of CGRP-IR in neurons associated with inflammation and calcitonin gene-related peptide
6) Confidence 0.29 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 16207882 Disease Relevance 1.41 Pain Relevance 1.51
In the bladder, most fibres were also substance P- or calcitonin gene-related peptide-immunoreactive but did not bind isolectin B4.
isolectin B4 Neg (not) Binding (bind) of calcitonin in bladder associated with calcitonin gene-related peptide and substance p
7) Confidence 0.28 Published 2002 Journal Neuroscience Section Abstract Doc Link 11927161 Disease Relevance 0.09 Pain Relevance 0.39
This antibody stained practically all DRG cells that contained calcitonin gene-related peptide and neurokinins and those that bound isolectin B4.
isolectin B4 Binding (bound) of calcitonin in DRG associated with calcitonin gene-related peptide
8) Confidence 0.21 Published 2002 Journal J. Comp. Neurol. Section Abstract Doc Link 11954032 Disease Relevance 0.07 Pain Relevance 0.31

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox