INT10228

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Context Info
Confidence 0.67
First Reported 1982
Last Reported 2010
Negated 2
Speculated 2
Reported most in Body
Documents 49
Total Number 51
Disease Relevance 28.72
Pain Relevance 7.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
B cells 2
His bundle 2
respiratory 2
plasma 1
internal 1
PCS (Homo sapiens)
Pain Link Frequency Relevance Heat
Versed 3 100.00 Very High Very High Very High
Fibrositis 66 99.44 Very High Very High Very High
Morphine 28 99.38 Very High Very High Very High
narcan 2 98.60 Very High Very High Very High
Ultiva 2 97.96 Very High Very High Very High
rheumatoid arthritis 101 97.92 Very High Very High Very High
Pain 130 97.76 Very High Very High Very High
backache 5 97.60 Very High Very High Very High
withdrawal 1 96.44 Very High Very High Very High
analgesia 13 94.12 High High
Disease Link Frequency Relevance Heat
Systemic Lupus Erythematosus 945 100.00 Very High Very High Very High
Rheumatoid Arthritis 111 100.00 Very High Very High Very High
Sleep Disorders 26 100.00 Very High Very High Very High
Head Trauma 5 100.00 Very High Very High Very High
Respiratory Disease 27 99.90 Very High Very High Very High
Weight Loss 7 99.90 Very High Very High Very High
Body Weight 7 99.86 Very High Very High Very High
Bursitis 56 99.82 Very High Very High Very High
Fibromyalgia 62 99.44 Very High Very High Very High
Diabetes Mellitus 89 99.28 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: In our cohort, the majority (83%) of the patients activated PCS during surgery under central neuraxial blocks at median time of 30 min and (17%) did not activate PCS.
Neg (not) Positive_regulation (activate) of PCS
1) Confidence 0.67 Published 2009 Journal J Postgrad Med Section Body Doc Link 19550055 Disease Relevance 0 Pain Relevance 0
To determine whether coronary sinus outflow pressure (Pcs) or intramyocardial tissue pressure (IMP) is the effective back pressure in the different layers of the left ventricular (LV) myocardium, we increased Pcs in 14 open-chest dogs under maximal coronary artery vasodilation.
Positive_regulation (increased) of Pcs in coronary artery associated with increased venous pressure under development
2) Confidence 0.67 Published 1992 Journal J. Appl. Physiol. Section Abstract Doc Link 1474101 Disease Relevance 0.10 Pain Relevance 0
RESULTS: In our cohort, the majority (83%) of the patients activated PCS during surgery under central neuraxial blocks at median time of 30 min and (17%) did not activate PCS.
Positive_regulation (activated) of PCS
3) Confidence 0.59 Published 2009 Journal J Postgrad Med Section Body Doc Link 19550055 Disease Relevance 0 Pain Relevance 0
Identifying acute PCS (within the first 14 days after injury) may optimise initial recovery and rehabilitation, identify those at risk and increase understanding of PCS.
Positive_regulation (increase) of PCS associated with head trauma and injury
4) Confidence 0.57 Published 2008 Journal J. Neurol. Neurosurg. Psychiatr. Section Abstract Doc Link 17702772 Disease Relevance 0.72 Pain Relevance 0
In SLE patients, we found disturbances of peripheral B-cell homeostasis with accumulation of IgD+ CD38++ transitional B cells and CD27++ PCs.
Positive_regulation (accumulation) of PCs in B cells associated with systemic lupus erythematosus
5) Confidence 0.44 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.58 Pain Relevance 0.08
One SLE patient (patient #1) showed an increase in the number of PCs at day 7 compared with day 3 that coincided with worsening of the patient's clinical condition (see the section on Materials and Methods).
Positive_regulation (increase) of PCs associated with systemic lupus erythematosus
6) Confidence 0.44 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.85 Pain Relevance 0
These findings may indicate that autoantibody production is not preceded by accumulation of CD27++ PCs.
Positive_regulation (accumulation) of PCs
7) Confidence 0.44 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 1.03 Pain Relevance 0
PCs was slightly increased compared with controls (P = 0.03).
Positive_regulation (increased) of PCs
8) Confidence 0.44 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.51 Pain Relevance 0
The patients preferred PCS to ACS on the basis of self-control, and because they had less discomfort during the recovery period.
Positive_regulation (preferred) of PCS
9) Confidence 0.43 Published 2008 Journal Burns Section Body Doc Link 18603377 Disease Relevance 0.13 Pain Relevance 0
There was a three-fold increase in the total number of personal computers (PCs) and particularly fast-processor PCs along with printers.
Positive_regulation (increase) of PCs
10) Confidence 0.42 Published 2007 Journal Global Health Section Body Doc Link PMC2206017 Disease Relevance 0.12 Pain Relevance 0
There was a three-fold increase in the total number of personal computers (PCs) and particularly fast-processor PCs along with printers.
Positive_regulation (increase) of PCs
11) Confidence 0.42 Published 2007 Journal Global Health Section Body Doc Link PMC2206017 Disease Relevance 0.12 Pain Relevance 0
In this study, we report increased mean PCS scores with increasing education, which has also been observed in a study of health-related quality of life among a cohort of 1991 Gulf War and Germany-deployed veterans [9].
Positive_regulation (increased) of PCS
12) Confidence 0.41 Published 2007 Journal BMC Public Health Section Body Doc Link PMC2212642 Disease Relevance 0.53 Pain Relevance 0.25
We observed the time to first PCS activation by patient, duration of surgery, propofol dose, sedation score, hemodynamic stability, patient's acceptability, and the factors correlating with the PCS use.
Positive_regulation (activation) of PCS
13) Confidence 0.39 Published 2009 Journal J Postgrad Med Section Body Doc Link 19550055 Disease Relevance 0 Pain Relevance 0
For example, for a subject with no problems in the musculoskeletal, neurological and vascular domains and no or mild problems in the psychiatric and upper gastrointestinal domains, the PCS for moderate or severe respiratory problem and severe cardiac problem can be estimated as:
Positive_regulation (estimated) of PCS in respiratory
14) Confidence 0.37 Published 2007 Journal Health Qual Life Outcomes Section Body Doc Link PMC2042974 Disease Relevance 0.51 Pain Relevance 0
For PCS, an increase in HRQL was likely to be associated with a higher educational level, while lower PCS scores were associated with: age 75+, inadequate household income, unmarried status, infrequency of seeing/meeting friends, too high a mean distance from own home to relatives' homes, lack of leisure time spent in recreational activities, living in the Centre-South of Italy, chronic diseases, reduced autonomy, and use of drugs during the previous two days.
Positive_regulation (increase) of PCS associated with chronic disease
15) Confidence 0.36 Published 2008 Journal BMC Public Health Section Abstract Doc Link PMC2569037 Disease Relevance 0.15 Pain Relevance 0
Eliminating effects of stimulus intensity resulted in two PCs (PC2, PC4) which distinguished exclusively between non-pain and pain.
Positive_regulation (resulted) of PCs associated with pain
16) Confidence 0.35 Published 1982 Journal Electroencephalogr Clin Neurophysiol Section Abstract Doc Link 6173204 Disease Relevance 0.32 Pain Relevance 0.35
It is unknown whether the presence of serum ANAs coincide with elevated frequencies of CD27++ PCs.
Spec (whether) Positive_regulation (frequencies) of PCs
17) Confidence 0.32 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 1.64 Pain Relevance 0
The frequency of CD27++ PCs has been shown to significantly correlate with SLE-disease activity: patients with active SLE had higher frequencies of PCs than patients with inactive SLE (12, 25).
Positive_regulation (frequency) of PCs associated with disease and systemic lupus erythematosus
18) Confidence 0.32 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 1.72 Pain Relevance 0
The frequency of CD27++ PCs has been shown to significantly correlate with SLE-disease activity: patients with active SLE had higher frequencies of PCs than patients with inactive SLE (12, 25).
Positive_regulation (frequencies) of PCs associated with disease and systemic lupus erythematosus
19) Confidence 0.32 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 1.71 Pain Relevance 0
Patients with systemic lupus erythematosus (SLE) exhibit an expanded population of CD27++ PCs, while the number of CD27?
Positive_regulation (population) of PCs associated with systemic lupus erythematosus
20) Confidence 0.32 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.82 Pain Relevance 0

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