INT102447

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Context Info
Confidence 0.26
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.33
Pain Relevance 1.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (CALCRL) aging (CALCA) endoplasmic reticulum (CALCRL)
intracellular (CALCA) signal transducer activity (CALCRL) cell-cell signaling (CALCA)
CALCA (Homo sapiens)
CALCRL (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 19 100.00 Very High Very High Very High
Neuropeptide 5 100.00 Very High Very High Very High
Migraine 5 93.84 High High
headache 3 93.12 High High
antagonist 14 86.00 High High
agonist 4 75.00 Quite High
Potency 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Migraine Disorders 4 93.84 High High
Headache Disorders 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The calcitonin receptor-like receptor (CLR) associates with the accessory protein RAMP1 to form a receptor for the neuropeptide calcitonin gene-related peptide (CGRP).
CGRP Binding (associates) of calcitonin receptor-like receptor associated with neuropeptide and calcitonin gene-related peptide
1) Confidence 0.26 Published 2010 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 20188075 Disease Relevance 0.16 Pain Relevance 0.73
CRLR combined with RAMP binds calcitonin gene-related peptide with high affinity, whereas CRLR coexpression with RAMP2 or -3 confers high-affinity binding of adrenomedullin.
gene-related peptide Binding (binds) of CRLR associated with calcitonin gene-related peptide
2) Confidence 0.24 Published 2002 Journal J. Cereb. Blood Flow Metab. Section Abstract Doc Link 11973435 Disease Relevance 0 Pain Relevance 0.22
The calcitonin receptor-like receptor (CLR) associates with the accessory protein RAMP1 to form a receptor for the neuropeptide calcitonin gene-related peptide (CGRP).
gene-related peptide Binding (associates) of calcitonin receptor-like receptor associated with neuropeptide and calcitonin gene-related peptide
3) Confidence 0.22 Published 2010 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 20188075 Disease Relevance 0.16 Pain Relevance 0.72

General Comments

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