INT102621

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Context Info
Confidence 0.13
First Reported 2002
Last Reported 2009
Negated 0
Speculated 2
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.78
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CPOX) extracellular space (IL6) small molecule metabolic process (CPOX)
oxidoreductase activity (CPOX) aging (IL6) extracellular region (IL6)
Anatomy Link Frequency
platelet 4
IL6 (Homo sapiens)
CPOX (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 5 98.28 Very High Very High Very High
Osteoarthritis 63 93.36 High High
imagery 1 26.88 Quite Low
COX2 2 10.00 Low Low
Inflammation 8 5.00 Very Low Very Low Very Low
cINOD 7 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Esophageal Cancer 4 94.44 High High
Disease Progression 2 93.48 High High
Osteoarthritis 66 93.36 High High
Obesity 15 5.00 Very Low Very Low Very Low
INFLAMMATION 11 5.00 Very Low Very Low Very Low
Osteophyte 2 5.00 Very Low Very Low Very Low
Skin Cancer 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Adenocarcinoma 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
METHODS: 59 ESCC samples were used to assess COX-2 expression in the tumor cells and four ESCC cell lines to investigate the effects of phorbol myristate acetate (PMA), platelet activating factor (PAF), n-sodium butyrate (n-BT) and interleukin-6 (IL-6) on the expression of COX-2.
IL-6 Spec (investigate) Regulation (effects) of Gene_expression (expression) of COX in platelet
1) Confidence 0.13 Published 2002 Journal Scand. J. Gastroenterol. Section Body Doc Link 11989839 Disease Relevance 0.19 Pain Relevance 0
METHODS: 59 ESCC samples were used to assess COX-2 expression in the tumor cells and four ESCC cell lines to investigate the effects of phorbol myristate acetate (PMA), platelet activating factor (PAF), n-sodium butyrate (n-BT) and interleukin-6 (IL-6) on the expression of COX-2.
interleukin-6 Spec (investigate) Regulation (effects) of Gene_expression (expression) of COX in platelet
2) Confidence 0.13 Published 2002 Journal Scand. J. Gastroenterol. Section Body Doc Link 11989839 Disease Relevance 0.19 Pain Relevance 0
(10 pg/mL) had a slight stimulatory effect on NO, PGE2, IL-6, and IL-8 production and iNOS and COX-2 expression (Figure 2).
IL-6 Regulation (effect) of Gene_expression (expression) of COX
3) Confidence 0.03 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2726438 Disease Relevance 0.41 Pain Relevance 0.25

General Comments

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