INT103130

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Context Info
Confidence 0.09
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL8) extracellular space (IL8) extracellular region (IL8)
intracellular (IL8) plasma membrane (DCSTAMP)
DCSTAMP (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 6 97.54 Very High Very High Very High
Disease Link Frequency Relevance Heat
Skin Cancer 8 99.84 Very High Very High Very High
Necrosis 1 88.08 High High
Cancer 1 87.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Addition of capsaicin (8-methyl-N-vanillyl-6-nonenamide), a known inhibitor of NF-kappaB, resulted in the inhibition of constitutive as well as IL-1beta-induced and TNF-alpha-induced IL-8 expression in melanoma cells.
IL-1beta-induced Positive_regulation (induced) of Gene_expression (expression) of IL-8 associated with qutenza and skin cancer
1) Confidence 0.09 Published 2002 Journal J. Interferon Cytokine Res. Section Abstract Doc Link 12034025 Disease Relevance 0.65 Pain Relevance 0.39

General Comments

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