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Context Info
Confidence 0.09
First Reported 2002
Last Reported 2003
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.86
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (DCSTAMP)
DCSTAMP (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 6 99.78 Very High Very High Very High
dexamethasone 1 97.36 Very High Very High Very High
cINOD 6 93.84 High High
COX-2 inhibitor 1 70.52 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Skin Cancer 8 99.36 Very High Very High Very High
INFLAMMATION 2 75.00 Quite High
Necrosis 1 69.52 Quite High
Cancer 1 69.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment with Flur, NS-398, Cig, and 15d-PGJ(2) alone, but not Indo and WY-14643, elevated COX activity; however, neither enhanced IL-1beta-induced COX activity.
Neg (neither) Positive_regulation (induced) of IL-1beta-induced
1) Confidence 0.09 Published 2003 Journal J. Immunol. Section Abstract Doc Link 12517972 Disease Relevance 0.14 Pain Relevance 0.37
Treatment of melanoma cells with capsaicin inhibited activation of constitutive and IL-1beta-induced NF-kappaB, but not AP-1, leading to inhibition of IL-8 expression.
Positive_regulation (activation) of IL-1beta-induced associated with qutenza and skin cancer
2) Confidence 0.06 Published 2002 Journal J. Interferon Cytokine Res. Section Abstract Doc Link 12034025 Disease Relevance 0.73 Pain Relevance 0.43

General Comments

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