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Context Info
Confidence 0.31
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (CALCA) intracellular (CALCA) cell-cell signaling (CALCA)
cytoplasm (CALCA) signal transducer activity (HTR1D) extracellular space (CALCA)
Anatomy Link Frequency
cranial 2
HTR1D (Homo sapiens)
CALCA (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 6 99.80 Very High Very High Very High
agonist 1 96.44 Very High Very High Very High
Migraine 1 95.28 Very High Very High Very High
headache 1 94.52 High High
medulla 2 82.80 Quite High
Disease Link Frequency Relevance Heat
Headache 2 95.28 Very High Very High Very High
Syndrome 1 94.00 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This suggests that 5-HT1D-receptors can regulate the release of CGRP and substance P and may be relevant to the clinical effectiveness of 5-HT1B/1D-receptor agonists in the treatment of migraine and other cranial pain syndromes.
5-HT1D Regulation (regulate) of Localization (release) of CGRP in cranial associated with syndrome, migraine, agonist, headache and substance p
1) Confidence 0.31 Published 2002 Journal Cephalalgia Section Abstract Doc Link 12133041 Disease Relevance 0.28 Pain Relevance 0.58

General Comments

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