INT104827

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Context Info
Confidence 0.07
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.13
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (IRF6, IL12A) cytosol (IRF6) extracellular space (IL12A)
extracellular region (IL12A) nucleus (IRF6) DNA binding (IRF6)
Anatomy Link Frequency
monocytes 1
IRF6 (Homo sapiens)
IL12A (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 11 87.88 High High
Opioid 1 84.12 Quite High
chemokine 6 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
diclofenac 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sarcoidosis 40 72.72 Quite High
Disease 9 46.72 Quite Low
Syndrome 19 44.92 Quite Low
Lymphocytosis 1 44.80 Quite Low
Nicotine Addiction 16 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Pulmonary Fibrosis 2 5.00 Very Low Very Low Very Low
Pulmonary Sarcoidosis 2 5.00 Very Low Very Low Very Low
Fibrosis 1 5.00 Very Low Very Low Very Low
Cough 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, they suppressed LPS-stimulated IL-10 and IL-12 production in THP-1 matured to monocytes by 1alpha,25-dihydroxyvitamin D3.
LPS Positive_regulation (stimulated) of IL-12 in monocytes
1) Confidence 0.07 Published 2002 Journal Scand. J. Immunol. Section Abstract Doc Link 12193227 Disease Relevance 0 Pain Relevance 0.16
LPS upregulated IL-12p35 and IL-23p19 in both groups (this was not statistically significant for IL-12p35 in controls, probably because of too few individuals).
LPS Positive_regulation (upregulated) of IL-12p35
2) Confidence 0.06 Published 2010 Journal Respir Res Section Body Doc Link PMC2939603 Disease Relevance 0.13 Pain Relevance 0

General Comments

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