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Context Info
Confidence 0.03
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Plat, NFKB1) nucleoplasm (NFKB1) mitochondrion (NFKB1)
cytosol (NFKB1) signal transduction (NFKB1) extracellular space (Plat)
Anatomy Link Frequency
HL-60 2
Plat (Mus musculus)
NFKB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 7 99.98 Very High Very High Very High
Inflammation 1 83.56 Quite High
Disease Link Frequency Relevance Heat
Cancer 2 96.60 Very High Very High Very High
Leukemia 2 94.88 High High
Nociception 1 84.40 Quite High
INFLAMMATION 1 83.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present work, we have found that capsaicin suppresses TPA-stimulated activation of NF-kappaB through inhibition of IkappaB alpha degradation and blockade of subsequent nuclear translocation of p65 in human promyelocytic leukemia HL-60 cells.
Negative_regulation (suppresses) of TPA Positive_regulation (activation) of NF-kappaB in HL-60 associated with leukemia and qutenza
1) Confidence 0.03 Published 2002 Journal Arch. Pharm. Res. Section Abstract Doc Link 12214859 Disease Relevance 0.53 Pain Relevance 0.54

General Comments

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