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Context Info
Confidence 0.50
First Reported 2002
Last Reported 2002
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK3) mitochondrion (MAPK3) Golgi apparatus (MAPK3)
protein complex assembly (MAPK3) protein complex (MAPK3) cytoplasm (MAPK3)
DYT10 (Homo sapiens)
MAPK3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 3 100.00 Very High Very High Very High
tolerance 3 93.16 High High
MU agonist 1 92.04 High High
agonist 2 75.00 Quite High
orphanin 2 73.00 Quite High
opioid receptor 1 43.56 Quite Low
Disease Link Frequency Relevance Heat
Neuroblastoma 1 46.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also demonstrate that chronic OFQ/N-mediated desensitization of ORL1 and mu receptors occurs via cell-specific pathways, involving ERK1/2-dependent GRK2, or PKC-dependent and ERK1/2-independent GRK3 induction.
PKC Neg (independent) Positive_regulation (induction) of ERK1 associated with kinase c
1) Confidence 0.50 Published 2002 Journal Neuropharmacology Section Abstract Doc Link 12423667 Disease Relevance 0 Pain Relevance 0.42

General Comments

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