INT106676

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(Generated page)
 
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|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2002
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2002|2002]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
Line 48: Line 48:
 
fontcolor=white,
 
fontcolor=white,
 
label="Binding",
 
label="Binding",
URL=Binding
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=E:Binding"
 
];
 
];
 
node2
 
node2
Line 56: Line 56:
 
fontcolor=white,
 
fontcolor=white,
 
label="Trpv1",
 
label="Trpv1",
URL="Trpv1"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:83810"
 
];
 
];
 
node3
 
node3
Line 64: Line 64:
 
fontcolor=white,
 
fontcolor=white,
 
label="Phax",
 
label="Phax",
URL="Phax"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:286917"
 
];
 
];
 
subgraph cluster_0 {
 
subgraph cluster_0 {
Line 78: Line 78:
 
{| cellspacing=5 cellpadding=2
 
{| cellspacing=5 cellpadding=2
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[nucleoplasm]] ([[Phax]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:nucleoplasm|nucleoplasm]] ([[G:286917|Phax]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[cytosol]] ([[Trpv1]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:cytosol|cytosol]] ([[G:83810|Trpv1]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[RNA binding]] ([[Phax]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:RNA binding|RNA binding]] ([[G:286917|Phax]])
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[nucleus]] ([[Phax]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:nucleus|nucleus]] ([[G:286917|Phax]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[plasma membrane]] ([[Trpv1]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:plasma membrane|plasma membrane]] ([[G:83810|Trpv1]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[cytoplasm]] ([[Phax]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:cytoplasm|cytoplasm]] ([[G:286917|Phax]])
 
|-
 
|-
 
|}
 
|}
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{| cellpadding=3 cellspacing=0  
 
{| cellpadding=3 cellspacing=0  
 
|-
 
|-
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Mention
+
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[CL:0000540|neurons]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:neurons|neurons]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|3
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|3
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:364|spinal cord]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:spinal cord|spinal cord]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:3477|paw]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:paw|paw]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
|-
 
|-
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[antagonist]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:qutenza|qutenza]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 60
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 231
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[TRP channel]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:antagonist|antagonist]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[qutenza]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:agonist|agonist]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 231
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[agonist]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:TRP channel|TRP channel]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 60
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 100.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Hyperalgesia]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Hyperalgesia|Hyperalgesia]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 82
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 82
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.62
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.62
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Analgesic]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Analgesic|Analgesic]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 44
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 44
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Lasting pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Lasting pain|Lasting pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 12
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 12
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.44
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.44
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Inflammation]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Inflammation|Inflammation]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 265
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 265
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Action potential]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Action potential|Action potential]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 17
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 17
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.20
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.20
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[IPN]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:IPN|IPN]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 10
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 10
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.24
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.24
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Hyperalgesia]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Hyperalgesia|Hyperalgesia]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 102
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 102
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.62
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.62
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Pain|Pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 109
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 109
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.44
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.44
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[INFLAMMATION]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:INFLAMMATION|INFLAMMATION]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 245
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 245
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Inflammatory Pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Inflammatory Pain|Inflammatory Pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 10
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 10
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.24
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 97.24
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Neuropathic Pain]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Neuropathic Pain|Neuropathic Pain]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 11
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 11
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 96.36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 96.36
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Nociception]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Nociception|Nociception]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 76
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 76
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 86.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 86.84
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Bone Cancer]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Bone Cancer|Bone Cancer]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 76.16
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 76.16
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Ganglion Cysts]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Ganglion Cysts|Ganglion Cysts]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 56
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 56
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 72.64
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 72.64
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Overactive Bladder]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Overactive Bladder|Overactive Bladder]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 65.68
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 65.68
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Abnormal Reflex]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Abnormal Reflex|Abnormal Reflex]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 56.32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 56.32
Line 259: Line 259:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''TRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">affinity</span>) of <span style="color:#800000">'''RTX'''</span> associated with <span style="color:#FF0000">'''qutenza'''</span>
+
|  [[G:83810|<span style="color:#800000">'''TRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">affinity</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]] associated with <span style="color:#FF0000">'''qutenza'''</span>
 
|-
 
|-
 
|}
 
|}
Line 270: Line 270:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.34
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.34
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2009
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2009|2009]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Neuroscience|Neuroscience]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Neuroscience|Neuroscience]]
Line 290: Line 290:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''TRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">affinity</span>) of <span style="color:#800000">'''RTX'''</span> in <span style="color:#808000">paw</span> associated with <span style="color:#FF0000">'''qutenza'''</span> and <span style="color:#FF0000">'''antagonist'''</span>
+
|  [[G:83810|<span style="color:#800000">'''TRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">affinity</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]] in [[A:paw|<span style="color:#808000">paw</span>]] associated with <span style="color:#FF0000">'''qutenza'''</span> and <span style="color:#FF0000">'''antagonist'''</span>
 
|-
 
|-
 
|}
 
|}
Line 301: Line 301:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.26
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2002
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2002|2002]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:J. Pharmacol. Exp. Ther.|J. Pharmacol. Exp. Ther.]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:J. Pharmacol. Exp. Ther.|J. Pharmacol. Exp. Ther.]]
Line 321: Line 321:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''TRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binding</span>) of <span style="color:#800000">'''RTX'''</span> in <span style="color:#808000">neurons</span>
+
|  [[G:83810|<span style="color:#800000">'''TRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binding</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]] in [[A:neurons|<span style="color:#808000">neurons</span>]]
 
|-
 
|-
 
|}
 
|}
Line 332: Line 332:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.11
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.11
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mol Pain|Mol Pain]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mol Pain|Mol Pain]]
Line 352: Line 352:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''vanilloid subfamily member 1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binds</span>) of <span style="color:#800000">'''RTX'''</span> in <span style="color:#808000">neurons</span> associated with <span style="color:#FF0000">'''trp channel'''</span>, <span style="color:#FF0000">'''qutenza'''</span> and <span style="color:#FF0000">'''agonist'''</span>
+
|  [[G:83810|<span style="color:#800000">'''vanilloid subfamily member 1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binds</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]] in [[A:neurons|<span style="color:#808000">neurons</span>]] associated with <span style="color:#FF0000">'''trp channel'''</span>, <span style="color:#FF0000">'''qutenza'''</span> and <span style="color:#FF0000">'''agonist'''</span>
 
|-
 
|-
 
|}
 
|}
Line 363: Line 363:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.11
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.11
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mol Pain|Mol Pain]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mol Pain|Mol Pain]]
Line 383: Line 383:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''TRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binds</span>) of <span style="color:#800000">'''RTX'''</span> in <span style="color:#808000">neurons</span> associated with <span style="color:#FF0000">'''trp channel'''</span>, <span style="color:#FF0000">'''qutenza'''</span> and <span style="color:#FF0000">'''agonist'''</span>
+
|  [[G:83810|<span style="color:#800000">'''TRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binds</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]] in [[A:neurons|<span style="color:#808000">neurons</span>]] associated with <span style="color:#FF0000">'''trp channel'''</span>, <span style="color:#FF0000">'''qutenza'''</span> and <span style="color:#FF0000">'''agonist'''</span>
 
|-
 
|-
 
|}
 
|}
Line 394: Line 394:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.11
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.11
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mol Pain|Mol Pain]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mol Pain|Mol Pain]]
Line 414: Line 414:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''TRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binds</span>) of <span style="color:#800000">'''RTX'''</span>
+
|  [[G:83810|<span style="color:#800000">'''TRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binds</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 425: Line 425:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.10
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.10
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2009
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2009|2009]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
Line 445: Line 445:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''TRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binds</span>) of <span style="color:#800000">'''RTX'''</span> in <span style="color:#808000">spinal cord</span> associated with <span style="color:#FF0000">'''spinal cord'''</span>
+
|  [[G:83810|<span style="color:#800000">'''TRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binds</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]] in [[A:spinal cord|<span style="color:#808000">spinal cord</span>]] associated with <span style="color:#FF0000">'''spinal cord'''</span>
 
|-
 
|-
 
|}
 
|}
Line 456: Line 456:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.10
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.10
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2009
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2009|2009]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:PLoS ONE|PLoS ONE]]
Line 478: Line 478:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''TRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binds</span>) of <span style="color:#800000">'''RTX'''</span> associated with <span style="color:#FF0000">'''hyperalgesia'''</span>, <span style="color:#FF0000">'''trp channel'''</span>, <span style="color:#FF0000">'''qutenza'''</span> and <span style="color:#FF0000">'''inflammation'''</span>
+
|  [[G:83810|<span style="color:#800000">'''TRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binds</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]] associated with <span style="color:#FF0000">'''hyperalgesia'''</span>, <span style="color:#FF0000">'''trp channel'''</span>, <span style="color:#FF0000">'''qutenza'''</span> and <span style="color:#FF0000">'''inflammation'''</span>
 
|-
 
|-
 
|}
 
|}
Line 489: Line 489:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.08
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.08
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mol Pain|Mol Pain]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mol Pain|Mol Pain]]
Line 511: Line 511:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''vanilloid subfamily member 1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binds</span>) of <span style="color:#800000">'''RTX'''</span> associated with <span style="color:#FF0000">'''hyperalgesia'''</span>, <span style="color:#FF0000">'''trp channel'''</span>, <span style="color:#FF0000">'''qutenza'''</span> and <span style="color:#FF0000">'''inflammation'''</span>
+
|  [[G:83810|<span style="color:#800000">'''vanilloid subfamily member 1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binds</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]] associated with <span style="color:#FF0000">'''hyperalgesia'''</span>, <span style="color:#FF0000">'''trp channel'''</span>, <span style="color:#FF0000">'''qutenza'''</span> and <span style="color:#FF0000">'''inflammation'''</span>
 
|-
 
|-
 
|}
 
|}
Line 522: Line 522:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.08
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.08
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mol Pain|Mol Pain]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Mol Pain|Mol Pain]]
Line 543: Line 543:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''TRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binds</span>) of <span style="color:#800000">'''Resiniferatoxin'''</span> associated with <span style="color:#FF0000">'''qutenza'''</span>
+
|  [[G:83810|<span style="color:#800000">'''TRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binds</span>) of [[G:286917|<span style="color:#800000">'''Resiniferatoxin'''</span>]] associated with <span style="color:#FF0000">'''qutenza'''</span>
 
|-
 
|-
 
|}
 
|}
Line 554: Line 554:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.05
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.05
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2004
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2004|2004]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]
Line 575: Line 575:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''capsaicin receptor'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binds</span>) of <span style="color:#800000">'''Resiniferatoxin'''</span> associated with <span style="color:#FF0000">'''qutenza'''</span>
+
|  [[G:83810|<span style="color:#800000">'''capsaicin receptor'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binds</span>) of [[G:286917|<span style="color:#800000">'''Resiniferatoxin'''</span>]] associated with <span style="color:#FF0000">'''qutenza'''</span>
 
|-
 
|-
 
|}
 
|}
Line 586: Line 586:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.05
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.05
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2004
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2004|2004]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]
Line 606: Line 606:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''TRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">bind</span>) of <span style="color:#800000">'''Resiniferatoxin'''</span> associated with <span style="color:#FF0000">'''antagonist'''</span> and <span style="color:#FF0000">'''agonist'''</span>
+
|  [[G:83810|<span style="color:#800000">'''TRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">bind</span>) of [[G:286917|<span style="color:#800000">'''Resiniferatoxin'''</span>]] associated with <span style="color:#FF0000">'''antagonist'''</span> and <span style="color:#FF0000">'''agonist'''</span>
 
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2004
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2004|2004]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]
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{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
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| <span style="color:#800000">'''TRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">bind</span>) of <span style="color:#800000">'''RTX'''</span> associated with <span style="color:#FF0000">'''antagonist'''</span> and <span style="color:#FF0000">'''agonist'''</span>
+
|  [[G:83810|<span style="color:#800000">'''TRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">bind</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]] associated with <span style="color:#FF0000">'''antagonist'''</span> and <span style="color:#FF0000">'''agonist'''</span>
 
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! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]
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{| cellpadding=4 cellspacing=2  
 
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| <span style="color:#800000">'''VR1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">ligand</span>) of <span style="color:#800000">'''RTX'''</span>
+
|  [[G:83810|<span style="color:#800000">'''VR1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">ligand</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]]
 
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2006
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2006|2006]]
 
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:J Negat Results Biomed|J Negat Results Biomed]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:J Negat Results Biomed|J Negat Results Biomed]]
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{| cellpadding=4 cellspacing=2  
 
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|-
 
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| <span style="color:#800000">'''rTRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">bind</span>) of <span style="color:#800000">'''Resiniferatoxin'''</span> associated with <span style="color:#FF0000">'''antagonist'''</span> and <span style="color:#FF0000">'''agonist'''</span>
+
|  [[G:83810|<span style="color:#800000">'''rTRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">bind</span>) of [[G:286917|<span style="color:#800000">'''Resiniferatoxin'''</span>]] associated with <span style="color:#FF0000">'''antagonist'''</span> and <span style="color:#FF0000">'''agonist'''</span>
 
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2004
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]
 
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| <span style="color:#800000">'''TRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">bind</span>) of <span style="color:#800000">'''RTX'''</span> associated with <span style="color:#FF0000">'''antagonist'''</span> and <span style="color:#FF0000">'''agonist'''</span>
+
|  [[G:83810|<span style="color:#800000">'''TRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">bind</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]] associated with <span style="color:#FF0000">'''antagonist'''</span> and <span style="color:#FF0000">'''agonist'''</span>
 
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]
 
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| <span style="color:#800000">'''rTRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binding</span>) of <span style="color:#800000">'''RTX'''</span>
+
|  [[G:83810|<span style="color:#800000">'''rTRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binding</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]]
 
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2004
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]
 
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| <span style="color:#800000">'''rTRPV1'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">bind</span>) of <span style="color:#800000">'''RTX'''</span> associated with <span style="color:#FF0000">'''antagonist'''</span> and <span style="color:#FF0000">'''agonist'''</span>
+
|  [[G:83810|<span style="color:#800000">'''rTRPV1'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">bind</span>) of [[G:286917|<span style="color:#800000">'''RTX'''</span>]] associated with <span style="color:#FF0000">'''antagonist'''</span> and <span style="color:#FF0000">'''agonist'''</span>
 
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Biochemistry|Biochemistry]]

Latest revision as of 11:51, 20 September 2012

Context Info
Confidence 0.34
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 18
Total Number 18
Disease Relevance 4.19
Pain Relevance 12.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Phax) cytosol (Trpv1) RNA binding (Phax)
nucleus (Phax) plasma membrane (Trpv1) cytoplasm (Phax)
Anatomy Link Frequency
neurons 3
spinal cord 1
paw 1
Trpv1 (Rattus norvegicus)
Phax (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 231 100.00 Very High Very High Very High
antagonist 60 100.00 Very High Very High Very High
agonist 60 100.00 Very High Very High Very High
TRP channel 8 100.00 Very High Very High Very High
Hyperalgesia 82 99.62 Very High Very High Very High
Analgesic 44 99.52 Very High Very High Very High
Lasting pain 12 99.44 Very High Very High Very High
Inflammation 265 99.36 Very High Very High Very High
Action potential 17 98.20 Very High Very High Very High
IPN 10 97.24 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hyperalgesia 102 99.62 Very High Very High Very High
Pain 109 99.44 Very High Very High Very High
INFLAMMATION 245 99.36 Very High Very High Very High
Inflammatory Pain 10 97.24 Very High Very High Very High
Neuropathic Pain 11 96.36 Very High Very High Very High
Nociception 76 86.84 High High
Bone Cancer 6 76.16 Quite High
Ganglion Cysts 56 72.64 Quite High
Overactive Bladder 2 65.68 Quite High
Abnormal Reflex 2 56.32 Quite High

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Resiniferatoxin (RTX) has a much higher affinity for TRPV1 than capsaicin, but its ability to modulate excitatory transmission is unclear.
TRPV1 Binding (affinity) of RTX associated with qutenza
1) Confidence 0.34 Published 2009 Journal Neuroscience Section Abstract Doc Link 19778582 Disease Relevance 0 Pain Relevance 0.50
Despite this activity and the high affinity of I-RTX for rat TRPV1, only capsazepine proved to be an effective antagonist of capsaicin-induced paw flinching in rats.
TRPV1 Binding (affinity) of RTX in paw associated with qutenza and antagonist
2) Confidence 0.26 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12438527 Disease Relevance 0.06 Pain Relevance 0.53
The binding of RTX leads to a sustained influx of sodium and calcium through TRPV1 channels [12] leading to channel desensitization and/or the loss of TRPV1-expressing DRG neurons and/or their fibers and terminals via calcium-induced cytotoxicity [13,14].
TRPV1 Binding (binding) of RTX in neurons
3) Confidence 0.11 Published 2010 Journal Mol Pain Section Body Doc Link PMC3019206 Disease Relevance 0.57 Pain Relevance 1.40
Resiniferatoxin (RTX), an ultrapotent capsaicin analog, is a vanilloid agonist that binds to the transient receptor potential channel, vanilloid subfamily member 1 (TRPV1), a non-selective cation ion channel expressed in small- and medium-sized neurons in sensory ganglia [1-3].
vanilloid subfamily member 1 Binding (binds) of RTX in neurons associated with trp channel, qutenza and agonist
4) Confidence 0.11 Published 2008 Journal Mol Pain Section Body Doc Link PMC2242785 Disease Relevance 0.48 Pain Relevance 0.57
Resiniferatoxin (RTX), an ultrapotent capsaicin analog, is a vanilloid agonist that binds to the transient receptor potential channel, vanilloid subfamily member 1 (TRPV1), a non-selective cation ion channel expressed in small- and medium-sized neurons in sensory ganglia [1-3].
TRPV1 Binding (binds) of RTX in neurons associated with trp channel, qutenza and agonist
5) Confidence 0.11 Published 2008 Journal Mol Pain Section Body Doc Link PMC2242785 Disease Relevance 0.49 Pain Relevance 0.57
These studies suggest that RTX binds to TRPV1 with high affinity and does not readily desensitize the receptor.
TRPV1 Binding (binds) of RTX
6) Confidence 0.10 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2737142 Disease Relevance 0.49 Pain Relevance 0.97
Since RTX binds to TRPV1 irreversibly and with high affinity, we propose this property will aid in its localization in a given segment of the spinal cord by slow infusion using osmotic mini pumps.
TRPV1 Binding (binds) of RTX in spinal cord associated with spinal cord
7) Confidence 0.10 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2737142 Disease Relevance 0.27 Pain Relevance 0.68
Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia

Resiniferatoxin (RTX) is an ultrapotent capsaicin analog that binds to the transient receptor potential channel, vanilloid subfamily member 1 (TRPV1).

TRPV1 Binding (binds) of RTX associated with hyperalgesia, trp channel, qutenza and inflammation
8) Confidence 0.08 Published 2008 Journal Mol Pain Section Title Doc Link PMC2242785 Disease Relevance 0.92 Pain Relevance 0.61
Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia

Resiniferatoxin (RTX) is an ultrapotent capsaicin analog that binds to the transient receptor potential channel, vanilloid subfamily member 1 (TRPV1).

vanilloid subfamily member 1 Binding (binds) of RTX associated with hyperalgesia, trp channel, qutenza and inflammation
9) Confidence 0.08 Published 2008 Journal Mol Pain Section Title Doc Link PMC2242785 Disease Relevance 0.92 Pain Relevance 0.61
Resiniferatoxin binds to the capsaicin receptor (TRPV1) near the extracellular side of the S4 transmembrane domain.
TRPV1 Binding (binds) of Resiniferatoxin associated with qutenza
10) Confidence 0.05 Published 2004 Journal Biochemistry Section Title Doc Link 14992587 Disease Relevance 0 Pain Relevance 0.76
Resiniferatoxin binds to the capsaicin receptor (TRPV1) near the extracellular side of the S4 transmembrane domain.
capsaicin receptor Binding (binds) of Resiniferatoxin associated with qutenza
11) Confidence 0.05 Published 2004 Journal Biochemistry Section Title Doc Link 14992587 Disease Relevance 0 Pain Relevance 0.76
Resiniferatoxin (RTX), a potent agonist of TRPV1, and iodoresiniferatoxin (I-RTX), a potent antagonist of TRPV1, both bind with higher affinity to the rat TRPV1 (rTRPV1) than the human (hTRPV1) isoform.
TRPV1 Binding (bind) of Resiniferatoxin associated with antagonist and agonist
12) Confidence 0.04 Published 2004 Journal Biochemistry Section Abstract Doc Link 14992587 Disease Relevance 0 Pain Relevance 0.61
Resiniferatoxin (RTX), a potent agonist of TRPV1, and iodoresiniferatoxin (I-RTX), a potent antagonist of TRPV1, both bind with higher affinity to the rat TRPV1 (rTRPV1) than the human (hTRPV1) isoform.
TRPV1 Binding (bind) of RTX associated with antagonist and agonist
13) Confidence 0.04 Published 2004 Journal Biochemistry Section Abstract Doc Link 14992587 Disease Relevance 0 Pain Relevance 0.60
Interestingly, RTX, a high affinity ligand for VR1, did alter regularly discharging BRs even at higher relative concentrations [20].
VR1 Binding (ligand) of RTX
14) Confidence 0.03 Published 2006 Journal J Negat Results Biomed Section Body Doc Link PMC1481593 Disease Relevance 0 Pain Relevance 0.79
Resiniferatoxin (RTX), a potent agonist of TRPV1, and iodoresiniferatoxin (I-RTX), a potent antagonist of TRPV1, both bind with higher affinity to the rat TRPV1 (rTRPV1) than the human (hTRPV1) isoform.
rTRPV1 Binding (bind) of Resiniferatoxin associated with antagonist and agonist
15) Confidence 0.03 Published 2004 Journal Biochemistry Section Abstract Doc Link 14992587 Disease Relevance 0 Pain Relevance 0.61
Resiniferatoxin (RTX), a potent agonist of TRPV1, and iodoresiniferatoxin (I-RTX), a potent antagonist of TRPV1, both bind with higher affinity to the rat TRPV1 (rTRPV1) than the human (hTRPV1) isoform.
TRPV1 Binding (bind) of RTX associated with antagonist and agonist
16) Confidence 0.03 Published 2004 Journal Biochemistry Section Abstract Doc Link 14992587 Disease Relevance 0 Pain Relevance 0.59
To identify the structural features responsible for this difference in affinity, [(3)H]RTX binding to chimeras between hTRPV1 and rTRPV1 was characterized.
rTRPV1 Binding (binding) of RTX
17) Confidence 0.03 Published 2004 Journal Biochemistry Section Abstract Doc Link 14992587 Disease Relevance 0 Pain Relevance 0.61
Resiniferatoxin (RTX), a potent agonist of TRPV1, and iodoresiniferatoxin (I-RTX), a potent antagonist of TRPV1, both bind with higher affinity to the rat TRPV1 (rTRPV1) than the human (hTRPV1) isoform.
rTRPV1 Binding (bind) of RTX associated with antagonist and agonist
18) Confidence 0.03 Published 2004 Journal Biochemistry Section Abstract Doc Link 14992587 Disease Relevance 0 Pain Relevance 0.59

[edit] General Comments

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