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Context Info
Confidence 0.19
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 1.02

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extracellular space (POMC, FN1) extracellular region (POMC, FN1) small molecule metabolic process (POMC)
cell-cell signaling (POMC) cytoplasm (POMC) generation of precursor metabolites and energy (POMC)
POMC (Homo sapiens)
FN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 15 99.40 Very High Very High Very High
Disease Link Frequency Relevance Heat
Skin Cancer 11 89.36 High High
Adhesions 1 75.00 Quite High
Cancer 2 58.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, binding to fibronectin was significantly reduced by alphaMSH in the wild type transfectants whereas this was not observed in the variant transfected clones; binding to laminin was not affected by alphaMSH in this cell line.
alphaMSH Negative_regulation (reduced) of fibronectin Binding (binding) of
1) Confidence 0.19 Published 2002 Journal Oncogene Section Abstract Doc Link 12439754 Disease Relevance 0.79 Pain Relevance 1.02

General Comments

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