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Context Info
Confidence 0.37
First Reported 2001
Last Reported 2002
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.10
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (P2ry2) aging (P2ry2) plasma membrane (P2ry2)
embryo development (P2ry2) lysosome (P2ry2) signal transducer activity (P2ry2)
Anatomy Link Frequency
sensory neurons 1
P2ry2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opiate 1 99.22 Very High Very High Very High
Action potential 1 88.44 High High
unmyelinated 1 76.08 Quite High
nociceptor 2 75.56 Quite High
narcan 1 65.72 Quite High
Disease Link Frequency Relevance Heat
Nociception 1 98.56 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, it is suggested that the inhibition by met-Enk of I(ATP) is caused by activation of opiate receptor, which eventually results in phosphorylation of ATP receptor, mediated by modulation of G protein coupling and intracellular signal transduction.
Phosphorylation (phosphorylation) of ATP receptor associated with opiate
1) Confidence 0.37 Published 2001 Journal Sheng Li Xue Bao Section Abstract Doc Link 12589405 Disease Relevance 0 Pain Relevance 0.13
ATP and UTP excite sensory neurons and induce CREB phosphorylation through the metabotropic receptor, P2Y2.
Phosphorylation (phosphorylation) of P2Y2 in sensory neurons
2) Confidence 0.24 Published 2002 Journal Eur. J. Neurosci. Section Title Doc Link 12453048 Disease Relevance 0.10 Pain Relevance 0.22

General Comments

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