INT107596

Context Info Confidence 0.00 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.13 Pain Relevance 0.77

cytosol (PPA1) cytoplasm (PPA1)

Anatomy Link Frequency OPLL 1 PPA1 (Homo sapiens) OPLL (Homo sapiens)

Pain Link Frequency Relevance Heat spinal inflammation 9 98.64

Disease Link Frequency Relevance Heat Seronegative Spondarthritis 10 98.64 Heterotopic Ossification 2 96.60 Rheumatic Diseases 2 92.28

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Recently, nucleotide pyrophosphatase (NPPS) was implicated in the aetiology of OPLL: an Npps mutation was found to cause OPLL in mice, and an association between a polymorphism of the human NPPS gene and OPLL was identified.

pyrophosphatase Binding (association) of OPLL in OPLL

1) Confidence 0.00 Published 2003 Journal Rheumatology (Oxford) Section Abstract Doc Link 12509614 Disease Relevance 1.13 Pain Relevance 0.77

General Comments

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