INT107705

Context Info Confidence 0.07 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0.36

nucleoplasm (NFKB1) mitochondrion (NFKB1) cytoplasm (NFKB1) cytosol (NFKB1) signal transduction (NFKB1) nucleolus (NFKB1)

DCSTAMP (Homo sapiens) NFKB1 (Homo sapiens)

Pain Link Frequency Relevance Heat dexamethasone 1 90.56 cINOD 6 81.92 COX-2 inhibitor 1 58.60 COX2 1 25.00

Disease Link Frequency Relevance Heat INFLAMMATION 2 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Unlike IL-1beta, NS-398 and Cig did not cause NF-kappaB (p65) nuclear translocation, nor did they further enhance IL-1beta-induced NF-kappaB translocation, but they stimulated PPARgamma translocation.

IL-1beta-induced Positive_regulation (induced) of Localization (translocation) of NF-kappaB

1) Confidence 0.07 Published 2003 Journal J. Immunol. Section Abstract Doc Link 12517972 Disease Relevance 0.07 Pain Relevance 0.36

General Comments

This test has worked.